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Angewandte Chemie - International Edition

Volumn 52, Issue 2, 2013, Pages 508-516

Molecular alliance - From orthosteric and allosteric ligands to dualsteric/bitopic agonists at G protein coupled receptors

(5) Mohr, Klaus b Schmitz, Jens a Schrage, Ramona b Tränkle, Christian b Holzgrabe, Ulrike a

a UNIVERSITY OF WÜRZBURG (Germany)

b UNIVERSITY OF BONN (Germany)

Author keywords

agonists; allosterism; antagonists; dualsterism; receptors

Indexed keywords

AGONISTS; ALLOSTERISM; ANTAGONISTS; DUALSTERISM; RECEPTORS;

BINDING SITES; BIOLOGICAL MEMBRANES; LIGANDS;

DRUG INTERACTIONS;

G PROTEIN COUPLED RECEPTOR; LIGAND;

ALLOSTERISM; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG DESIGN; HUMAN; METABOLISM; PROTEIN BINDING; REVIEW; SIGNAL TRANSDUCTION;

ALLOSTERIC REGULATION; ALLOSTERIC SITE; DRUG DESIGN; HUMANS; LIGANDS; MODELS, MOLECULAR; PROTEIN BINDING; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION;

EID: 84871980480 PISSN: 14337851 EISSN: 15213773 Source Type: Journal
DOI: 10.1002/anie.201205315 Document Type: Review

Times cited : (77)

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