Time-dependent changes in the microenvironment of injured spinal cord affects the therapeutic potential of neural stem cell transplantation for spinal cord injury

Molecular Brain

Volumn 6, Issue 1, 2013, Pages

  Nishimura, Soraya ^a,b   Yasuda, Akimasa ^a   Iwai, Hiroki ^a,b   Takano, Morito ^a,b   Kobayashi, Yoshiomi ^a,b   Nori, Satoshi ^a   Tsuji, Osahiko ^c   Fujiyoshi, Kanehiro ^d   Ebise, Hayao ^e   Toyama, Yoshiaki ^a   Okano, Hideyuki ^b   Nakamura, Masaya ^a  

^a Department of Orthopaedic Surgery ^*  (Japan)

^b KEIO UNIVERSITY   (Japan)

^c Saitama Social Insurance Hospital   (Japan)

^d NATIONAL HOSPITAL ORGANIZATION MURAYAMA MEDICAL CENTER   (Japan)

^e DAINIPPON SUMITOMO PHARMA CO LTD   (Japan)

Author keywords

Cell transplantation; Chronic phase; Microenvironment; Neural stem progenitor cells; Spinal cord injury

Indexed keywords

CYTOKINE; GROWTH FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BRAIN CONTUSION; CELL DIFFERENTIATION; CELL FATE; CELL INFILTRATION; CELL SURVIVAL; CELL TRANSPLANTATION; CONTROLLED STUDY; CYTOKINE RELEASE; FEMALE; GENE EXPRESSION; GLIA CELL; GRAFT SURVIVAL; HISTOLOGY; IMMUNOHISTOLOGY; MACROPHAGE; MICROARRAY ANALYSIS; MICROENVIRONMENT; MOUSE; NEURAL STEM CELL; NEURAL STEM CELL TRANSPLANTATION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SCAR; SPINAL CORD INJURY;

ACTION POTENTIALS; ACUTE DISEASE; ANIMALS; AXONS; CELL DIFFERENTIATION; CELLULAR MICROENVIRONMENT; CHRONIC DISEASE; CICATRIX; FEMALE; LUCIFERASES; LUMINESCENT PROTEINS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MOTOR ACTIVITY; MYELIN SHEATH; NEURAL STEM CELLS; NEUROGLIA; PHENOTYPE; SPINAL CORD INJURIES; STEM CELL TRANSPLANTATION; TIME FACTORS;

ANIMALIA; MUS;

EID: 84871962001     PISSN: None     EISSN: 17566606     Source Type: Journal    
DOI: 10.1186/1756-6606-6-3     Document Type: Article

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