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Volumn 393, Issue 4, 2010, Pages 812-817

Transplanted neural progenitor cells expressing mutant NT3 promote myelination and partial hindlimb recovery in the chronic phase after spinal cord injury

Author keywords

Chronic phase; Neural progenitor cells; Neurotrophins; Spinal cord injury; Transplantation

Indexed keywords

ABELSON KINASE; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; NEUROTROPHIC FACTOR; NEUTROTROPHIN 3; UNCLASSIFIED DRUG;

EID: 77949487367     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2010.02.088     Document Type: Article
Times cited : (46)

References (34)
  • 1
    • 0029082495 scopus 로고
    • Developmental changes in NT3 signalling via TrkA and TrkB in embryonic neurons
    • Davies A.M., Minichiello L., and Klein R. Developmental changes in NT3 signalling via TrkA and TrkB in embryonic neurons. EMBO J. 14 (1995) 4482-4489
    • (1995) EMBO J. , vol.14 , pp. 4482-4489
    • Davies, A.M.1    Minichiello, L.2    Klein, R.3
  • 2
    • 0029583047 scopus 로고
    • Early expression of the nerve growth factor receptor ctrkA in chick sympathetic and sensory ganglia
    • Schröpel A., von Schack D., Dechant G., and Barde Y.A. Early expression of the nerve growth factor receptor ctrkA in chick sympathetic and sensory ganglia. Mol. Cell. Neurosci. 6 (1995) 544-566
    • (1995) Mol. Cell. Neurosci. , vol.6 , pp. 544-566
    • Schröpel, A.1    von Schack, D.2    Dechant, G.3    Barde, Y.A.4
  • 3
    • 0034803770 scopus 로고    scopus 로고
    • Complete ablation of the neurotrophin receptor p75NTR causes defects both in the nervous and the vascular system
    • von Schack D., Casademunt E., Schweigreiter R., Meyer M., Bibel M., and Dechant G. Complete ablation of the neurotrophin receptor p75NTR causes defects both in the nervous and the vascular system. Nat. Neurosci. 4 (2001) 977-978
    • (2001) Nat. Neurosci. , vol.4 , pp. 977-978
    • von Schack, D.1    Casademunt, E.2    Schweigreiter, R.3    Meyer, M.4    Bibel, M.5    Dechant, G.6
  • 4
    • 0141535172 scopus 로고    scopus 로고
    • Chronic neurotrophin-3 strengthens synaptic connections to motoneurons in the neonatal rat
    • Arvanian V.L., Horner P.J., Gage F.H., and Mendell L.M. Chronic neurotrophin-3 strengthens synaptic connections to motoneurons in the neonatal rat. J. Neurosci. 23 (2003) 8706-8712
    • (2003) J. Neurosci. , vol.23 , pp. 8706-8712
    • Arvanian, V.L.1    Horner, P.J.2    Gage, F.H.3    Mendell, L.M.4
  • 5
    • 37549055474 scopus 로고    scopus 로고
    • Selective deletion of BDNF in the ventromedial and dorsomedical hypothalamus of adult mice results in hyperphagic behavior and obesity
    • Unger T.J., Calderon G.A., Bradley L.C., Sena-Esteves M., and Rios M. Selective deletion of BDNF in the ventromedial and dorsomedical hypothalamus of adult mice results in hyperphagic behavior and obesity. J. Neurosci. 27 (2007) 14265-14274
    • (2007) J. Neurosci. , vol.27 , pp. 14265-14274
    • Unger, T.J.1    Calderon, G.A.2    Bradley, L.C.3    Sena-Esteves, M.4    Rios, M.5
  • 6
    • 40149098353 scopus 로고    scopus 로고
    • Presynaptic functional trkB receptors mediate the release of excitatory neurotransmitters from primary afferent terminals in lamina II (substantia gelatinosa) of postnatal rat spinal cord
    • Merighi A., Bardoni R., Salio C., Lossi L., Ferrini F., Prandini M., Zonta M., Gustincich S., and Carmignoto G. Presynaptic functional trkB receptors mediate the release of excitatory neurotransmitters from primary afferent terminals in lamina II (substantia gelatinosa) of postnatal rat spinal cord. Dev. Neurobiol. 68 (2008) 457-475
    • (2008) Dev. Neurobiol. , vol.68 , pp. 457-475
    • Merighi, A.1    Bardoni, R.2    Salio, C.3    Lossi, L.4    Ferrini, F.5    Prandini, M.6    Zonta, M.7    Gustincich, S.8    Carmignoto, G.9
  • 7
    • 58249110567 scopus 로고    scopus 로고
    • Cardiovascular actions of neurotrophins
    • Caporali A., and Emanueli C. Cardiovascular actions of neurotrophins. Physiol. Rev. 89 (2009) 279-308
    • (2009) Physiol. Rev. , vol.89 , pp. 279-308
    • Caporali, A.1    Emanueli, C.2
  • 8
    • 0030973478 scopus 로고    scopus 로고
    • Functional characterization of NGF-secreting cell grafts to the acutely injured spinal cord
    • Tuszynski M.H., Murai K., Blesch A., Grill R., and Miller I. Functional characterization of NGF-secreting cell grafts to the acutely injured spinal cord. Cell Transplant. 6 (1997) 361-368
    • (1997) Cell Transplant. , vol.6 , pp. 361-368
    • Tuszynski, M.H.1    Murai, K.2    Blesch, A.3    Grill, R.4    Miller, I.5
  • 9
    • 0031919140 scopus 로고    scopus 로고
    • Grafts of genetically modified Schwann cells to the spinal cord: survival, axon growth, and myelination
    • Tuszynski M.H., Weidner N., McCormack M., Miller I., Powell H., and Conner J. Grafts of genetically modified Schwann cells to the spinal cord: survival, axon growth, and myelination. Cell Transplant. 7 (1998) 187-196
    • (1998) Cell Transplant. , vol.7 , pp. 187-196
    • Tuszynski, M.H.1    Weidner, N.2    McCormack, M.3    Miller, I.4    Powell, H.5    Conner, J.6
  • 10
    • 11844273931 scopus 로고    scopus 로고
    • BDNF-expressing marrow stromal cells support extensive axonal growth at sites of spinal cord injury
    • Lu P., Jones L.L., and Tuszynski M.H. BDNF-expressing marrow stromal cells support extensive axonal growth at sites of spinal cord injury. Exp. Neurol. 191 (2005) 344-360
    • (2005) Exp. Neurol. , vol.191 , pp. 344-360
    • Lu, P.1    Jones, L.L.2    Tuszynski, M.H.3
  • 11
    • 22044438251 scopus 로고    scopus 로고
    • Transplants of fibroblasts expressing BDNF and NT-3 promote recovery of bladder and hindlimb function following spinal contusion injury in rats
    • Mitsui T., Fischer I., Shumsky J.S., and Murray M. Transplants of fibroblasts expressing BDNF and NT-3 promote recovery of bladder and hindlimb function following spinal contusion injury in rats. Exp. Neurol. 194 (2005) 410-431
    • (2005) Exp. Neurol. , vol.194 , pp. 410-431
    • Mitsui, T.1    Fischer, I.2    Shumsky, J.S.3    Murray, M.4
  • 12
    • 0028559164 scopus 로고
    • The binding epitopes of neurotrophin-3 to its receptors trkC and gp75 and the design of a multifunctional human neurotrophin
    • Urfer R., Tsoulfas P., Soppet D., Escandón E., Parada L.F., and Presta L.G. The binding epitopes of neurotrophin-3 to its receptors trkC and gp75 and the design of a multifunctional human neurotrophin. EMBO J. 13 (1994) 5896-5909
    • (1994) EMBO J. , vol.13 , pp. 5896-5909
    • Urfer, R.1    Tsoulfas, P.2    Soppet, D.3    Escandón, E.4    Parada, L.F.5    Presta, L.G.6
  • 13
    • 0032534610 scopus 로고    scopus 로고
    • NT-3-mediated TrkC receptor activation promotes proliferation and cell survival of rodent progenitor oligodendrocyte cells in vitro and in vivo
    • Kumar S., Kahn M.A., Dinh L., and de Vellis J. NT-3-mediated TrkC receptor activation promotes proliferation and cell survival of rodent progenitor oligodendrocyte cells in vitro and in vivo. J. Neurosci. Res. 54 (1998) 754-765
    • (1998) J. Neurosci. Res. , vol.54 , pp. 754-765
    • Kumar, S.1    Kahn, M.A.2    Dinh, L.3    de Vellis, J.4
  • 14
    • 0033635904 scopus 로고    scopus 로고
    • Neurotrophins: key regulators of cell fate and cell shape in the vertebrate nervous system
    • Bibel M., and Barde Y.A. Neurotrophins: key regulators of cell fate and cell shape in the vertebrate nervous system. Genes Dev. 14 (2000) 2919-2937
    • (2000) Genes Dev. , vol.14 , pp. 2919-2937
    • Bibel, M.1    Barde, Y.A.2
  • 15
    • 0037044576 scopus 로고    scopus 로고
    • The neurotrophin receptor p75NTR as a positive modulator of myelination
    • Cosgaya J.M., Chan J.R., and Shooter E.M. The neurotrophin receptor p75NTR as a positive modulator of myelination. Science 298 (2002) 1245-1248
    • (2002) Science , vol.298 , pp. 1245-1248
    • Cosgaya, J.M.1    Chan, J.R.2    Shooter, E.M.3
  • 16
    • 23044446572 scopus 로고    scopus 로고
    • Functional recovery in traumatic spinal cord injury after transplantation of multineurotrophin-expressing glial restricted precursor cells
    • Cao Q., Xu X.M., Devries W.H., Enzmann G.U., Ping P., Tsoulfas P., Wood P.M., Bunge M.B., and Whittemore S.R. Functional recovery in traumatic spinal cord injury after transplantation of multineurotrophin-expressing glial restricted precursor cells. J. Neurosci. 25 (2005) 6947-6957
    • (2005) J. Neurosci. , vol.25 , pp. 6947-6957
    • Cao, Q.1    Xu, X.M.2    Devries, W.H.3    Enzmann, G.U.4    Ping, P.5    Tsoulfas, P.6    Wood, P.M.7    Bunge, M.B.8    Whittemore, S.R.9
  • 18
    • 0031408944 scopus 로고    scopus 로고
    • Robust growth of chronically injured spinal cord axons induced by grafts of genetically modified NGF-secreting cells
    • Grill R.J., Blesch A., and Tuszynski M.H. Robust growth of chronically injured spinal cord axons induced by grafts of genetically modified NGF-secreting cells. Exp. Neurol. 148 (1997) 444-452
    • (1997) Exp. Neurol. , vol.148 , pp. 444-452
    • Grill, R.J.1    Blesch, A.2    Tuszynski, M.H.3
  • 19
    • 0036434324 scopus 로고    scopus 로고
    • Transplants of fibroblasts genetically modified to express BDNF promote axonal regeneration from supraspinal neurons following chronic spinal cord injury
    • Jin Y., Fischer I., Tessler A., and Houle J.D. Transplants of fibroblasts genetically modified to express BDNF promote axonal regeneration from supraspinal neurons following chronic spinal cord injury. Exp. Neurol. 177 (2002) 265-275
    • (2002) Exp. Neurol. , vol.177 , pp. 265-275
    • Jin, Y.1    Fischer, I.2    Tessler, A.3    Houle, J.D.4
  • 20
    • 28644449557 scopus 로고    scopus 로고
    • Lentiviral vector-mediated transduction of neural progenitor cells before implantation into injured spinal cord and brain to detect their migration, deliver neurotrophic factors and repair tissue
    • Blits B., Kitay B.M., Farahvar A., Caperton C.V., Dietrich W.D., and Bunge M.B. Lentiviral vector-mediated transduction of neural progenitor cells before implantation into injured spinal cord and brain to detect their migration, deliver neurotrophic factors and repair tissue. Restor. Neurol. Neurosci. 23 (2005) 313-324
    • (2005) Restor. Neurol. Neurosci. , vol.23 , pp. 313-324
    • Blits, B.1    Kitay, B.M.2    Farahvar, A.3    Caperton, C.V.4    Dietrich, W.D.5    Bunge, M.B.6
  • 21
    • 0036370361 scopus 로고    scopus 로고
    • Generation of HIV-1 derived lentiviral vectors
    • Follenzi A., and Naldini L. Generation of HIV-1 derived lentiviral vectors. Methods Enzymol. 346 (2002) 454-465
    • (2002) Methods Enzymol. , vol.346 , pp. 454-465
    • Follenzi, A.1    Naldini, L.2
  • 22
    • 0030448423 scopus 로고    scopus 로고
    • Single factors direct the differentiation of stem cells from the fetal and adult central nervous system
    • Johe K.K., Hazel T.G., Muller T., Dugich-Djordjevic M.M., and McKay R.D. Single factors direct the differentiation of stem cells from the fetal and adult central nervous system. Genes Dev. 10 (1996) 3129-3140
    • (1996) Genes Dev. , vol.10 , pp. 3129-3140
    • Johe, K.K.1    Hazel, T.G.2    Muller, T.3    Dugich-Djordjevic, M.M.4    McKay, R.D.5
  • 23
    • 0030157694 scopus 로고    scopus 로고
    • Graded histological and locomotor outcomes after spinal cord contusion using the NYU weight-drop device versus transaction
    • Basso D.M., Beattie M.S., and Bresnahan J.C. Graded histological and locomotor outcomes after spinal cord contusion using the NYU weight-drop device versus transaction. Exp. Neurol. 139 (1996) 244-256
    • (1996) Exp. Neurol. , vol.139 , pp. 244-256
    • Basso, D.M.1    Beattie, M.S.2    Bresnahan, J.C.3
  • 24
    • 0032798378 scopus 로고    scopus 로고
    • Experimental spinal cord contusion injury: comparison of different outcome parameters
    • Lankhorst A.J., Verzijl M.R., and Hamers F.P.T. Experimental spinal cord contusion injury: comparison of different outcome parameters. Neurosci. Res. Commun. 24 (1999) 135-148
    • (1999) Neurosci. Res. Commun. , vol.24 , pp. 135-148
    • Lankhorst, A.J.1    Verzijl, M.R.2    Hamers, F.P.T.3
  • 25
    • 0032838089 scopus 로고    scopus 로고
    • Depletion of hematogenous macrophages promotes partial hindlimb recovery and neuroanatomical repair after experimental spinal cord injury
    • Popovich P.G., Guan Z., Wei P., Huitinga I., van Rooijen N., and Stokes B.T. Depletion of hematogenous macrophages promotes partial hindlimb recovery and neuroanatomical repair after experimental spinal cord injury. Exp. Neurol. 158 (1999) 351-365
    • (1999) Exp. Neurol. , vol.158 , pp. 351-365
    • Popovich, P.G.1    Guan, Z.2    Wei, P.3    Huitinga, I.4    van Rooijen, N.5    Stokes, B.T.6
  • 26
    • 33646576505 scopus 로고    scopus 로고
    • Functional considerations of stem cell transplantation therapy for spinal cord repair
    • Enzmann G.U., Benton R.L., Talbott J.F., Cao Q., and Whittemore S.R. Functional considerations of stem cell transplantation therapy for spinal cord repair. J. Neurotrauma 23 (2006) 479-495
    • (2006) J. Neurotrauma , vol.23 , pp. 479-495
    • Enzmann, G.U.1    Benton, R.L.2    Talbott, J.F.3    Cao, Q.4    Whittemore, S.R.5
  • 27
    • 0041317188 scopus 로고    scopus 로고
    • Adult neural progenitor cell grafts survive after acute spinal cord injury and integrate along axonal pathways
    • Vroemen M., Aigner L., Winkler J., and Weidner N. Adult neural progenitor cell grafts survive after acute spinal cord injury and integrate along axonal pathways. Eur. J. Neurosci. 18 (2003) 743-751
    • (2003) Eur. J. Neurosci. , vol.18 , pp. 743-751
    • Vroemen, M.1    Aigner, L.2    Winkler, J.3    Weidner, N.4
  • 28
    • 0037106211 scopus 로고    scopus 로고
    • Transplantation of in vitro-expanded fetal neural progenitor cells results in neurogenesis and functional recovery after spinal cord contusion injury in adult rats
    • Ogawa Y., Sawamoto K., Miyata T., Miyao S., Watanabe M., Nakamura M., Bregman B.S., Koike M., Uchiyama Y., Toyama Y., and Okano H. Transplantation of in vitro-expanded fetal neural progenitor cells results in neurogenesis and functional recovery after spinal cord contusion injury in adult rats. J. Neurosci. Res. 69 (2002) 925-933
    • (2002) J. Neurosci. Res. , vol.69 , pp. 925-933
    • Ogawa, Y.1    Sawamoto, K.2    Miyata, T.3    Miyao, S.4    Watanabe, M.5    Nakamura, M.6    Bregman, B.S.7    Koike, M.8    Uchiyama, Y.9    Toyama, Y.10    Okano, H.11
  • 29
    • 0035148507 scopus 로고    scopus 로고
    • Pluripotent stem cells engrafted into the normal or lesioned adult rat spinal cord are restricted to a glial lineage
    • Cao Q.L., Zhang Y.P., Howard R.M., Walters W.M., Tsoulfas P., and Whittemore S.R. Pluripotent stem cells engrafted into the normal or lesioned adult rat spinal cord are restricted to a glial lineage. Exp. Neurol. 167 (2001) 48-58
    • (2001) Exp. Neurol. , vol.167 , pp. 48-58
    • Cao, Q.L.1    Zhang, Y.P.2    Howard, R.M.3    Walters, W.M.4    Tsoulfas, P.5    Whittemore, S.R.6
  • 30
    • 0037362044 scopus 로고    scopus 로고
    • Migration and differentiation of neural progenitor cells from two different regions of embryonic central nervous system after transplantation into the intact spinal cord
    • Enomoto M., Shinomiya K., and Okabe S. Migration and differentiation of neural progenitor cells from two different regions of embryonic central nervous system after transplantation into the intact spinal cord. Eur. J. Neurosci. 17 (2003) 1223-1232
    • (2003) Eur. J. Neurosci. , vol.17 , pp. 1223-1232
    • Enomoto, M.1    Shinomiya, K.2    Okabe, S.3
  • 31
    • 0035873540 scopus 로고    scopus 로고
    • Neurotrophic factors and receptors in the immature and adult spinal cord after mechanical injury or kainic acid
    • Widenfalk J., Lundstromer K., Jubran M., Brene S., and Olson L. Neurotrophic factors and receptors in the immature and adult spinal cord after mechanical injury or kainic acid. J. Neurosci. 21 (2001) 3457-3475
    • (2001) J. Neurosci. , vol.21 , pp. 3457-3475
    • Widenfalk, J.1    Lundstromer, K.2    Jubran, M.3    Brene, S.4    Olson, L.5
  • 32
    • 0035152176 scopus 로고    scopus 로고
    • Regulation of Trk receptors following contusion of the rat spinal cord
    • Liebl D.J., Huang W., Young W., and Parada L.F. Regulation of Trk receptors following contusion of the rat spinal cord. Exp. Neurol. 167 (2001) 15-26
    • (2001) Exp. Neurol. , vol.167 , pp. 15-26
    • Liebl, D.J.1    Huang, W.2    Young, W.3    Parada, L.F.4
  • 33
    • 0038060385 scopus 로고    scopus 로고
    • Neurotrophins in myelination: a new role for a puzzling receptor
    • Notterpek L. Neurotrophins in myelination: a new role for a puzzling receptor. Trends Neurosci. 26 (2003) 232-234
    • (2003) Trends Neurosci. , vol.26 , pp. 232-234
    • Notterpek, L.1
  • 34
    • 0032529351 scopus 로고    scopus 로고
    • Transplanted olfactory ensheathing cells remyelinate and enhance axonal conduction in the demyelinated dorsal columns of the rat spinal cord
    • Imaizumi T., Lankford K.L., Waxman S.G., Greer C.A., and Kocsis J.D. Transplanted olfactory ensheathing cells remyelinate and enhance axonal conduction in the demyelinated dorsal columns of the rat spinal cord. J. Neurosci. 18 (1998) 6176-6185
    • (1998) J. Neurosci. , vol.18 , pp. 6176-6185
    • Imaizumi, T.1    Lankford, K.L.2    Waxman, S.G.3    Greer, C.A.4    Kocsis, J.D.5


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