A novel monoclonal antibody reveals a conformational alteration shared by amyotrophic lateral sclerosis-linked SOD1 mutants

Annals of Neurology

Volumn 72, Issue 5, 2012, Pages 739-749

  Fujisawa, Takao ^a   Homma, Kengo ^a   Yamaguchi, Namiko ^a   Kadowaki, Hisae ^a,c   Tsuburaya, Naomi ^a   Naguro, Isao ^a   Matsuzawa, Atsushi ^a   Takeda, Kohsuke ^a,d   Takahashi, Yuji ^b   Goto, Jun ^b   Tsuji, Shoji ^b   Nishitoh, Hideki ^a,c   Ichijo, Hidenori ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c UNIVERSITY OF MIYAZAKI   (Japan)

^d NAGASAKI UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

COPPER ZINC SUPEROXIDE DISMUTASE; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY MS785; UNCLASSIFIED DRUG;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL CELL; ARTICLE; B LYMPHOCYTE; CLINICAL ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN BINDING; RAT;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; ANTIBODIES, MONOCLONAL; CELL DEATH; CELLS, CULTURED; CULTURE MEDIA, SERUM-FREE; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; HUMANS; IMMUNOPRECIPITATION; MEMBRANE PROTEINS; MICE; MICE, INBRED ICR; MICE, TRANSGENIC; MOTOR NEURONS; MUTATION; PROTEIN BINDING; PROTEIN CONFORMATION; SPINAL CORD; SUPEROXIDE DISMUTASE; TRANSFECTION;

EID: 84871961507     PISSN: 03645134     EISSN: 15318249     Source Type: Journal    
DOI: 10.1002/ana.23668     Document Type: Article

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