메뉴 건너뛰기




Volumn 20, Issue 1, 2013, Pages 21-27

Common theme for drugs effective in overactive bladder treatment: Inhibition of afferent signaling from the bladder

Author keywords

Mirabegron; Mucosal signaling; Myogenic pathway; Onabotulinum toxin A; Tadalafil

Indexed keywords

4 [2 [[2 (3 CHLOROPHENYL) 2 HYDROXYETHYL]AMINO]PROPYL]PHENOXYACETIC ACID; 5 [2 [[2 (3 CHLOROPHENYL) 2 HYDROXYETHYL]AMINO]PROPYL] 1,3 BENZODIOXOLE 2,2 DICARBOXYLIC ACID; BOTULINUM TOXIN A; MIRABEGRON; SILDENAFIL; TADALAFIL; TOLTERODINE; VARDENAFIL;

EID: 84871937932     PISSN: 09198172     EISSN: 14422042     Source Type: Journal    
DOI: 10.1111/j.1442-2042.2012.03196.x     Document Type: Review
Times cited : (29)

References (71)
  • 1
    • 77949336457 scopus 로고    scopus 로고
    • Bladder afferent signaling: recent findings
    • Kanai A, Andersson KE. Bladder afferent signaling: recent findings. J. Urol. 2010; 183: 1288-1295.
    • (2010) J. Urol. , vol.183 , pp. 1288-1295
    • Kanai, A.1    Andersson, K.E.2
  • 2
    • 79551485468 scopus 로고    scopus 로고
    • Antimuscarinic mechanisms and the overactive detrusor: an update
    • Andersson KE. Antimuscarinic mechanisms and the overactive detrusor: an update. Eur. Urol. 2011; 59: 377-386.
    • (2011) Eur. Urol. , vol.59 , pp. 377-386
    • Andersson, K.E.1
  • 3
    • 0031444212 scopus 로고    scopus 로고
    • A neurologic basis for the overactive bladder
    • de Groat WC. A neurologic basis for the overactive bladder. Urology 1997; 50: 36-52.
    • (1997) Urology , vol.50 , pp. 36-52
    • de Groat, W.C.1
  • 4
    • 3042637079 scopus 로고    scopus 로고
    • Urinary bladder contraction and relaxation: physiology and pathophysiology
    • Andersson KE, Arner A. Urinary bladder contraction and relaxation: physiology and pathophysiology. Physiol. Rev. 2004; 84: 935-986.
    • (2004) Physiol. Rev. , vol.84 , pp. 935-986
    • Andersson, K.E.1    Arner, A.2
  • 5
    • 1342299961 scopus 로고    scopus 로고
    • The autonomous bladder: a view of the origin of bladder overactivity and sensory urge
    • Gillespie JI. The autonomous bladder: a view of the origin of bladder overactivity and sensory urge. BJU Int. 2004; 93: 478-483.
    • (2004) BJU Int. , vol.93 , pp. 478-483
    • Gillespie, J.I.1
  • 6
    • 66149135242 scopus 로고    scopus 로고
    • On the origins of the sensory output from the bladder: the concept of afferent noise
    • Gillespie JI, van Koeveringe GA, de Wachter SG, de Vente J. On the origins of the sensory output from the bladder: the concept of afferent noise. BJU Int. 2009; 103: 1324-1333.
    • (2009) BJU Int. , vol.103 , pp. 1324-1333
    • Gillespie, J.I.1    van Koeveringe, G.A.2    de Wachter, S.G.3    de Vente, J.4
  • 7
    • 33846054863 scopus 로고    scopus 로고
    • Mechanisms of disease: involvement of the urothelium in bladder dysfunction
    • Birder LA, de Groat WC. Mechanisms of disease: involvement of the urothelium in bladder dysfunction. Nat. Clin. Pract. Urol. 2007; 4: 46-54.
    • (2007) Nat. Clin. Pract. Urol. , vol.4 , pp. 46-54
    • Birder, L.A.1    de Groat, W.C.2
  • 8
  • 9
    • 0037830662 scopus 로고    scopus 로고
    • A quantitative analysis of mRNA expression of alpha 1 and β-adrenoreceptor subtypes and their functional roles in human normal and obstructed bladders
    • Nomiya M, Yamaguchi O. A quantitative analysis of mRNA expression of alpha 1 and β-adrenoreceptor subtypes and their functional roles in human normal and obstructed bladders. J. Urol. 2003; 170 (2 Pt 1): 649-653.
    • (2003) J. Urol. , vol.170 , Issue.2 PART 1 , pp. 649-653
    • Nomiya, M.1    Yamaguchi, O.2
  • 10
    • 32544437708 scopus 로고    scopus 로고
    • Alpha1-, alpha2- and β-adrenoreceptors in the urinary bladder, urethra and prostate
    • Michel MC, Vrydag W. Alpha1-, alpha2- and β-adrenoreceptors in the urinary bladder, urethra and prostate. Br. J. Pharmacol. 2006; 147 (Suppl 2): S88.
    • (2006) Br. J. Pharmacol. , vol.147 , Issue.SUPPL. 2
    • Michel, M.C.1    Vrydag, W.2
  • 11
    • 78650897515 scopus 로고    scopus 로고
    • β3-adrenoreceptor agonists: possible role in the treatment of overactive bladder
    • Igawa Y, Aizawa N, Homma Y. β3-adrenoreceptor agonists: possible role in the treatment of overactive bladder. Korean J. Urol. 2010; 51: 811-818.
    • (2010) Korean J. Urol. , vol.51 , pp. 811-818
    • Igawa, Y.1    Aizawa, N.2    Homma, Y.3
  • 12
    • 3142617911 scopus 로고
    • Tension receptors in the stomach and the urinary bladder
    • Iggo A. Tension receptors in the stomach and the urinary bladder. J. Physiol. 1955; 128: 593-607.
    • (1955) J. Physiol. , vol.128 , pp. 593-607
    • Iggo, A.1
  • 13
    • 33750891388 scopus 로고    scopus 로고
    • The effects of a new selective beta3-adrenoceptor agonist (GW427353) on spontaneous activity and detrusor relaxation in human bladder
    • Biers SM, Reynard JM, Brading AF. The effects of a new selective beta3-adrenoceptor agonist (GW427353) on spontaneous activity and detrusor relaxation in human bladder. BJU Int. 2006; 98: 1310-1314.
    • (2006) BJU Int. , vol.98 , pp. 1310-1314
    • Biers, S.M.1    Reynard, J.M.2    Brading, A.F.3
  • 14
    • 77955557104 scopus 로고    scopus 로고
    • Effects of CL316,243, a β3 adrenoreceptor agonist, and intravesical prostaglandin E2 on the primary bladder afferent activity of the rat
    • Aizawa N, Igawa Y, Nishizawa O, Wyndaele JJ. Effects of CL316, 243, a β3 adrenoreceptor agonist, and intravesical prostaglandin E2 on the primary bladder afferent activity of the rat. Neurourol. Urodyn. 2010; 29: 771-776.
    • (2010) Neurourol. Urodyn. , vol.29 , pp. 771-776
    • Aizawa, N.1    Igawa, Y.2    Nishizawa, O.3    Wyndaele, J.J.4
  • 15
    • 84863551967 scopus 로고    scopus 로고
    • Modulation of non-voiding activity by the muscarinergic antagonist tolterodine and the β(3) -adrenoceptor agonist mirabegron in conscious rats with partial outflow obstruction
    • Gillespie JI, Palea S, Guilloteau V, Guerard M, Lluel P, Korstanje C. Modulation of non-voiding activity by the muscarinergic antagonist tolterodine and the β(3) -adrenoceptor agonist mirabegron in conscious rats with partial outflow obstruction. BJU Int. 2012; 110 (2 Pt B): E132-142.
    • (2012) BJU Int. , vol.110 , Issue.2 PART B
    • Gillespie, J.I.1    Palea, S.2    Guilloteau, V.3    Guerard, M.4    Lluel, P.5    Korstanje, C.6
  • 16
    • 79959839075 scopus 로고    scopus 로고
    • Researching bladder afferents - determining the effects of β3-adrenergic receptor agonists and botulinum toxin type-A
    • Kanai A, Wyndaele J, Andersson KE etal. Researching bladder afferents - determining the effects of β3-adrenergic receptor agonists and botulinum toxin type-A. Neurourol. Urodyn. 2011; 30: 684-691.
    • (2011) Neurourol. Urodyn. , vol.30 , pp. 684-691
    • Kanai, A.1    Wyndaele, J.2    Andersson, K.E.3
  • 17
    • 78651107932 scopus 로고    scopus 로고
    • Urothelial β-3 adrenergic receptors in the rat bladder
    • Kullmann FA, Downs TR, Artim DE etal. Urothelial β-3 adrenergic receptors in the rat bladder. Neurourol. Urodyn. 2011; 30: 144-150.
    • (2011) Neurourol. Urodyn. , vol.30 , pp. 144-150
    • Kullmann, F.A.1    Downs, T.R.2    Artim, D.E.3
  • 19
    • 0031846997 scopus 로고    scopus 로고
    • Adrenergic- and capsaicin-evoked nitric oxide release from urothelium and afferent nerves in urinary bladder
    • Birder LA, Apodaca G, de Groat WC, Kanai AJ. Adrenergic- and capsaicin-evoked nitric oxide release from urothelium and afferent nerves in urinary bladder. Am. J. Physiol. 1998; 275: F226-229.
    • (1998) Am. J. Physiol. , vol.275
    • Birder, L.A.1    de Apodaca, G.2    Groat, W.C.3    Kanai, A.J.4
  • 22
    • 47149090579 scopus 로고    scopus 로고
    • 3 adrenoreceptor agonist YM178 is effective and well tolerated in the treatment of symptoms of overactive bladder
    • abstract 674
    • 3 adrenoreceptor agonist YM178 is effective and well tolerated in the treatment of symptoms of overactive bladder. Eur. Urol. Suppl. 2008; 7: 239 (abstract 674).
    • (2008) Eur. Urol. Suppl. , vol.7 , pp. 239
    • Chapple, C.R.1    Yamaguchi, O.2    Ridder, A.3
  • 24
    • 79956198842 scopus 로고    scopus 로고
    • The efficacy and safety of mirabegron in patients with overactive bladder syndrome - results from a North American Phase III trial
    • abstract 885
    • Nitti V, Herschorn S, Auerbach S, Ayers M, Lee M, Martin N. The efficacy and safety of mirabegron in patients with overactive bladder syndrome - results from a North American Phase III trial. Eur. Urol. Suppl 2011; 10: 278 (abstract 885).
    • (2011) Eur. Urol. Suppl , vol.10 , pp. 278
    • Nitti, V.1    Herschorn, S.2    Auerbach, S.3    Ayers, M.4    Lee, M.5    Martin, N.6
  • 25
    • 79956199048 scopus 로고    scopus 로고
    • The efficacy and tolerability of mirabegron in patients with overactive bladder - results from a European-Australian Phase III trial
    • abstract 886
    • Khullar V, Cabronero J, Strömberg P etal. The efficacy and tolerability of mirabegron in patients with overactive bladder - results from a European-Australian Phase III trial. Eur. Urol. Suppl 2011; 10: 278 (abstract 886).
    • (2011) Eur. Urol. Suppl , vol.10 , pp. 278
    • Khullar, V.1    Cabronero, J.2    Strömberg, P.3
  • 26
    • 79960902595 scopus 로고    scopus 로고
    • Treatment of erectile dysfunction and lower urinary tract symptoms by phosphodiesterase inhibitors
    • Uckert S, Stief CG. Treatment of erectile dysfunction and lower urinary tract symptoms by phosphodiesterase inhibitors. Handb. Exp. Pharmacol. 2011; 204: 307-322.
    • (2011) Handb. Exp. Pharmacol. , vol.204 , pp. 307-322
    • Uckert, S.1    Stief, C.G.2
  • 27
    • 79952749220 scopus 로고    scopus 로고
    • Tadalafil for the treatment of lower urinary tract symptoms secondary to benign prostatic hyperplasia: pathophysiology and mechanism(s) of action
    • Andersson KE, de Groat WC, McVary KT etal. Tadalafil for the treatment of lower urinary tract symptoms secondary to benign prostatic hyperplasia: pathophysiology and mechanism(s) of action. Neurourol. Urodyn. 2011; 30: 292-301.
    • (2011) Neurourol. Urodyn. , vol.30 , pp. 292-301
    • Andersson, K.E.1    de Groat, W.C.2    McVary, K.T.3
  • 28
    • 35148853274 scopus 로고    scopus 로고
    • Phosphodiesterases (PDEs) and PDE inhibitors for treatment of LUTS
    • Andersson KE, Uckert S, Stief C, Hedlund P. Phosphodiesterases (PDEs) and PDE inhibitors for treatment of LUTS. Neurourol. Urodyn. 2007; 26 (6 Suppl): 928-933.
    • (2007) Neurourol. Urodyn. , vol.26 , Issue.6 SUPPL. , pp. 928-933
    • Andersson, K.E.1    Uckert, S.2    Stief, C.3    Hedlund, P.4
  • 29
    • 74049146047 scopus 로고    scopus 로고
    • Characterization of phosphodiesterase type 5 expression and functional activity in the human male lower urinary tract
    • Fibbi B, Morelli A, Vignozzi L etal. Characterization of phosphodiesterase type 5 expression and functional activity in the human male lower urinary tract. J. Sex. Med. 2010; 7: 59-69.
    • (2010) J. Sex. Med. , vol.7 , pp. 59-69
    • Fibbi, B.1    Morelli, A.2    Vignozzi, L.3
  • 30
    • 75849123577 scopus 로고    scopus 로고
    • Urodynamic effects of once daily tadalafil in men with lower urinary tract symptoms secondary to clinical benign prostatic hyperplasia: a randomized, placebo controlled 12-week clinical trial
    • Dmochowski R, Roehrborn C, Klise S, Xu L, Kaminetsky J, Kraus S. Urodynamic effects of once daily tadalafil in men with lower urinary tract symptoms secondary to clinical benign prostatic hyperplasia: a randomized, placebo controlled 12-week clinical trial. J. Urol. 2010; 183: 1092-1097.
    • (2010) J. Urol. , vol.183 , pp. 1092-1097
    • Dmochowski, R.1    Roehrborn, C.2    Klise, S.3    Xu, L.4    Kaminetsky, J.5    Kraus, S.6
  • 31
    • 77953198703 scopus 로고    scopus 로고
    • Signalling pathways involved in sildenafil-induced relaxation of human bladder dome smooth muscle
    • Oger S, Behr-Roussel D, Gorny D etal. Signalling pathways involved in sildenafil-induced relaxation of human bladder dome smooth muscle. Br. J. Pharmacol. 2010; 160: 1135-1143.
    • (2010) Br. J. Pharmacol. , vol.160 , pp. 1135-1143
    • Oger, S.1    Behr-Roussel, D.2    Gorny, D.3
  • 32
    • 40649120162 scopus 로고    scopus 로고
    • Effects of phosphodiesterase inhibitors on tension induced by norepinephrine and accumulation of cyclic nucleotides in isolated human prostatic tissue
    • Uckert S, Sormes M, Kedia G etal. Effects of phosphodiesterase inhibitors on tension induced by norepinephrine and accumulation of cyclic nucleotides in isolated human prostatic tissue. Urology 2008; 71: 526-530.
    • (2008) Urology , vol.71 , pp. 526-530
    • Uckert, S.1    Sormes, M.2    Kedia, G.3
  • 33
    • 33745698509 scopus 로고    scopus 로고
    • Phosphodiesterase 5 in the female pig and human urethra: morphological and functional aspects
    • Werkström V, Svensson A, Andersson KE, Hedlund P. Phosphodiesterase 5 in the female pig and human urethra: morphological and functional aspects. BJU Int. 2006; 98: 414-423.
    • (2006) BJU Int. , vol.98 , pp. 414-423
    • Werkström, V.1    Svensson, A.2    Andersson, K.E.3    Hedlund, P.4
  • 34
    • 84871930031 scopus 로고    scopus 로고
    • In vitro functional responses of isolated human urethral tissue to phosphodiesterase (PDE) inhibitors
    • abstract 931
    • Kedia GT, Sonnenberg JE, Kuczyk MA, Uckert S. In vitro functional responses of isolated human urethral tissue to phosphodiesterase (PDE) inhibitors. Eur. Urol. Suppl. 2011; 10: 291-292 (abstract 931).
    • (2011) Eur. Urol. Suppl. , vol.10 , pp. 291-292
    • Kedia, G.T.1    Sonnenberg, J.E.2    Kuczyk, M.A.3    Uckert, S.4
  • 35
    • 78650681639 scopus 로고    scopus 로고
    • Nitric oxide/cyclic guanosine monophosphate signaling mediates an inhibitory action on sensory pathways of the micturition reflex in the rat
    • Caremel R, Oger-Roussel S, Behr-Roussel D, Grise P, Giuliano FA. Nitric oxide/cyclic guanosine monophosphate signaling mediates an inhibitory action on sensory pathways of the micturition reflex in the rat. Eur. Urol. 2010; 58: 616-625.
    • (2010) Eur. Urol. , vol.58 , pp. 616-625
    • Caremel, R.1    Oger-Roussel, S.2    Behr-Roussel, D.3    Grise, P.4    Giuliano, F.A.5
  • 36
    • 0026728299 scopus 로고
    • Effects of inhibition of the L-arginine/nitric oxide pathway in the rat lower urinary tract in vivo and in vitro
    • Persson K, Igawa Y, Mattiasson A, Andersson KE. Effects of inhibition of the L-arginine/nitric oxide pathway in the rat lower urinary tract in vivo and in vitro. Br. J. Pharmacol. 1992; 107: 178-184.
    • (1992) Br. J. Pharmacol. , vol.107 , pp. 178-184
    • Persson, K.1    Igawa, Y.2    Mattiasson, A.3    Andersson, K.E.4
  • 37
    • 0033941718 scopus 로고    scopus 로고
    • Intravesical oxyhemoglobin initiates bladder overactivity in conscious, normal rats
    • Pandita RK, Mizusawa H, Andersson KE. Intravesical oxyhemoglobin initiates bladder overactivity in conscious, normal rats. J. Urol. 2000; 164: 545-550.
    • (2000) J. Urol. , vol.164 , pp. 545-550
    • Pandita, R.K.1    Mizusawa, H.2    Andersson, K.E.3
  • 38
    • 50249167766 scopus 로고    scopus 로고
    • Nitric oxide-mediated suppression of detrusor overactivity by arginase inhibitor in rats with chronic spinal cord injury
    • Sesatomi K, Hiragata S, Miyazato M, Chancellor M, Morris S, Yoshimura N. Nitric oxide-mediated suppression of detrusor overactivity by arginase inhibitor in rats with chronic spinal cord injury. Urology 2008; 72: 696-700.
    • (2008) Urology , vol.72 , pp. 696-700
    • Sesatomi, K.1    Hiragata, S.2    Miyazato, M.3    Chancellor, M.4    Morris, S.5    Yoshimura, N.6
  • 39
    • 68049102221 scopus 로고    scopus 로고
    • Activation of the nitric oxide-cGMP pathway reduces phasic contractions in neonatal rat bladder strips via protein kinase G
    • Artim DE, Kullman FA, Daughtery SL, Wu H, de Groat WC. Activation of the nitric oxide-cGMP pathway reduces phasic contractions in neonatal rat bladder strips via protein kinase G. Am. J. Physiol. Renal Physiol. 2009; 297: F333-340.
    • (2009) Am. J. Physiol. Renal Physiol. , vol.297
    • Artim, D.E.1    Kullman, F.A.2    Daughtery, S.L.3    de Wu, H.4    Groat, W.C.5
  • 40
    • 0034943472 scopus 로고    scopus 로고
    • Nitric oxide modulates Ca(2+) channels in dorsal root ganglion neurons innervating rat urinary bladder
    • Yoshimura N, Skei S, de Groat WC. Nitric oxide modulates Ca(2+) channels in dorsal root ganglion neurons innervating rat urinary bladder. J. Neurophysiol. 2001; 86: 304-311.
    • (2001) J. Neurophysiol. , vol.86 , pp. 304-311
    • Yoshimura, N.1    de Skei, S.2    Groat, W.C.3
  • 41
    • 84859102437 scopus 로고    scopus 로고
    • Mechanisms of action of botulinum neurotoxins, β3-adrenergic receptor agonists, and PDE5 inhibitors in modulating detrusor function in overactive bladders: ICI-RS 2011
    • Kanai A, Zabbarova I, Oefelein M, Radziszewski P, Ikeda Y, Andersson KE. Mechanisms of action of botulinum neurotoxins, β3-adrenergic receptor agonists, and PDE5 inhibitors in modulating detrusor function in overactive bladders: ICI-RS 2011. Neurourol. Urodyn. 2012; 31: 300-308.
    • (2012) Neurourol. Urodyn. , vol.31 , pp. 300-308
    • Kanai, A.1    Zabbarova, I.2    Oefelein, M.3    Radziszewski, P.4    Ikeda, Y.5    Andersson, K.E.6
  • 42
    • 34247278766 scopus 로고    scopus 로고
    • Neurokinins enhance excitability in capsaicin-responsive DRG neurons
    • Sculptoreanu A, de Groat WC. Neurokinins enhance excitability in capsaicin-responsive DRG neurons. Exp. Neurol. 2007; 205: 92-100.
    • (2007) Exp. Neurol. , vol.205 , pp. 92-100
    • Sculptoreanu, A.1    de Groat, W.C.2
  • 43
    • 69749099126 scopus 로고    scopus 로고
    • Neurokinins inhibit low threshold inactivating K+ currents in capsaicin responsive DRG neurons
    • Sculptoreanu A, Artim DE, de Groat WC. Neurokinins inhibit low threshold inactivating K+ currents in capsaicin responsive DRG neurons. Exp. Neurol. 2009; 219: 562-573.
    • (2009) Exp. Neurol. , vol.219 , pp. 562-573
    • Sculptoreanu, A.1    de Artim, D.E.2    Groat, W.C.3
  • 44
    • 78650702653 scopus 로고    scopus 로고
    • Vardenafil decrease bladder afferent nerve activity unanesthetized, decerebrate, spinal cord-injured rats
    • Behr-Roussel D, Oger S, Caisey S etal. Vardenafil decrease bladder afferent nerve activity unanesthetized, decerebrate, spinal cord-injured rats. Eur. Urol. 2011; 59: 272-279.
    • (2011) Eur. Urol. , vol.59 , pp. 272-279
    • Behr-Roussel, D.1    Oger, S.2    Caisey, S.3
  • 45
    • 84865511771 scopus 로고    scopus 로고
    • Inhibitory effects of phosphodiesterase 5 inhibitor, tadalafil, on mechanosensitive bladder afferent nerve activities of the rat and on acrolien-induced hyperactivity of these nerves
    • Minegawa T, Aizawa N, Igawa Y etal. Inhibitory effects of phosphodiesterase 5 inhibitor, tadalafil, on mechanosensitive bladder afferent nerve activities of the rat and on acrolien-induced hyperactivity of these nerves. BJU Int. 2012; 110: E259-266.
    • (2012) BJU Int. , vol.110
    • Minegawa, T.1    Aizawa, N.2    Igawa, Y.3
  • 46
    • 78650714708 scopus 로고    scopus 로고
    • Effects of nitric oxide on the primary bladder afferent activities of the rat with and without intravesical acrolein treatment
    • Aizawa N, Igawa Y, Nishizawa O etal. Effects of nitric oxide on the primary bladder afferent activities of the rat with and without intravesical acrolein treatment. Eur. Urol. 2011; 59: 264-271.
    • (2011) Eur. Urol. , vol.59 , pp. 264-271
    • Aizawa, N.1    Igawa, Y.2    Nishizawa, O.3
  • 47
    • 84872139801 scopus 로고    scopus 로고
    • Prophylactic effect of tadalafil on bladder function in a rat model of chronic bladder ischemia
    • doi: 10.1016/j.juro.2012.07.141.
    • Nomiya M, Burmeister DM, Sawada N etal. Prophylactic effect of tadalafil on bladder function in a rat model of chronic bladder ischemia. J. Urol. 2012; doi: 10.1016/j.juro.2012.07.141.
    • (2012) J. Urol.
    • Nomiya, M.1    Burmeister, D.M.2    Sawada, N.3
  • 48
    • 33947266450 scopus 로고    scopus 로고
    • Tadalafil relieves lower urinary tract symptoms secondary to benign prostatic hyperplasia
    • McVary KT, Roehrborn CG, Kaminetsky JC etal. Tadalafil relieves lower urinary tract symptoms secondary to benign prostatic hyperplasia. J. Urol. 2007; 177: 1401-1407.
    • (2007) J. Urol. , vol.177 , pp. 1401-1407
    • McVary, K.T.1    Roehrborn, C.G.2    Kaminetsky, J.C.3
  • 49
    • 50949119951 scopus 로고    scopus 로고
    • Tadalafil administered once daily for lower urinary tract symptoms secondary to benign prostatic hyperplasia: a dose finding study
    • Roehrborn CG, McVary KT, Elion-Mboussa A, Viktrup L. Tadalafil administered once daily for lower urinary tract symptoms secondary to benign prostatic hyperplasia: a dose finding study. J. Urol. 2008; 180: 1228-1234.
    • (2008) J. Urol. , vol.180 , pp. 1228-1234
    • Roehrborn, C.G.1    McVary, K.T.2    Elion-Mboussa, A.3    Viktrup, L.4
  • 50
    • 76149134714 scopus 로고    scopus 로고
    • Changes in peak urinary flow and voiding efficiency in men with signs and symptoms of benign prostatic hyperplasia during once daily tadalafil treatment
    • Roehrborn CG, Kaminetsky JC, Auerbach SM etal. Changes in peak urinary flow and voiding efficiency in men with signs and symptoms of benign prostatic hyperplasia during once daily tadalafil treatment. BJU Int. 2010; 105: 502-507.
    • (2010) BJU Int. , vol.105 , pp. 502-507
    • Roehrborn, C.G.1    Kaminetsky, J.C.2    Auerbach, S.M.3
  • 51
    • 42749084255 scopus 로고    scopus 로고
    • A randomised, placebo-controlled study to assess the efficacy of twice-daily vardenafil in the treatment of lower urinary tract symptoms secondary to benign prostatic hyperplasia
    • Stief CG, Porst H, Neuser D, Beneke M, Ulbrich E. A randomised, placebo-controlled study to assess the efficacy of twice-daily vardenafil in the treatment of lower urinary tract symptoms secondary to benign prostatic hyperplasia. Eur. Urol. 2008; 53: 1236-1244.
    • (2008) Eur. Urol. , vol.53 , pp. 1236-1244
    • Stief, C.G.1    Porst, H.2    Neuser, D.3    Beneke, M.4    Ulbrich, E.5
  • 52
    • 79960994565 scopus 로고    scopus 로고
    • Phosphodiesterase type 5 inhibitors in the management of non-neurogenic male lower urinary tract symptoms: critical analysis of current evidence
    • Martínez-Salamanca JI, Carballido J, Eardley I etal. Phosphodiesterase type 5 inhibitors in the management of non-neurogenic male lower urinary tract symptoms: critical analysis of current evidence. Eur. Urol. 2011; 60: 527-535.
    • (2011) Eur. Urol. , vol.60 , pp. 527-535
    • Martínez-Salamanca, J.I.1    Carballido, J.2    Eardley, I.3
  • 53
    • 0034121745 scopus 로고    scopus 로고
    • How botulinum and tetanus neurotoxins block neurotransmitter release
    • Humeau Y, Doussau F, Grant NJ, Poulain B. How botulinum and tetanus neurotoxins block neurotransmitter release. Biochimie 2000; 82: 427-446.
    • (2000) Biochimie , vol.82 , pp. 427-446
    • Humeau, Y.1    Doussau, F.2    Grant, N.J.3    Poulain, B.4
  • 54
    • 44949091513 scopus 로고    scopus 로고
    • Drug Insight: biological effects of botulinum toxin A in the lower urinary tract
    • Chancellor MB, Fowler CJ, Apostolidis A etal. Drug Insight: biological effects of botulinum toxin A in the lower urinary tract. Nat. Clin. Pract. Urol. 2008; 5: 319-328.
    • (2008) Nat. Clin. Pract. Urol. , vol.5 , pp. 319-328
    • Chancellor, M.B.1    Fowler, C.J.2    Apostolidis, A.3
  • 55
    • 84860271852 scopus 로고    scopus 로고
    • Spread of onabotulinumtoxinA after bladder injection. Experimental study using the distribution of cleaved SNAP-25 as the marker of the toxin action
    • Coelho A, Cruz F, Cruz CD, Avelino A. Spread of onabotulinumtoxinA after bladder injection. Experimental study using the distribution of cleaved SNAP-25 as the marker of the toxin action. Eur. Urol. 2012; 61: 1178-1184.
    • (2012) Eur. Urol. , vol.61 , pp. 1178-1184
    • Coelho, A.1    Cruz, F.2    Cruz, C.D.3    Avelino, A.4
  • 56
    • 84868529759 scopus 로고    scopus 로고
    • Botulinum neurotoxin serotype A suppresses neurotransmitter release from afferent as well as efferent nerves in the urinary bladder
    • doi:10.1016/j.eururo.2012.03.031.
    • Ikeda Y, Zabbarova I, Birder L etal. Botulinum neurotoxin serotype A suppresses neurotransmitter release from afferent as well as efferent nerves in the urinary bladder. Eur. Urol. 2012; doi:10.1016/j.eururo.2012.03.031.
    • (2012) Eur. Urol.
    • Ikeda, Y.1    Zabbarova, I.2    Birder, L.3
  • 57
    • 26444469528 scopus 로고    scopus 로고
    • Review of a proposed mechanism for the antinociceptive action of botulinum toxin type A
    • Aoki KR. Review of a proposed mechanism for the antinociceptive action of botulinum toxin type A. Neurotoxicology 2005; 26: 785-793.
    • (2005) Neurotoxicology , vol.26 , pp. 785-793
    • Aoki, K.R.1
  • 58
    • 32044462256 scopus 로고    scopus 로고
    • Botulinum toxin type A inhibits calcitonin gen-related peptide release from isolated rat bladder
    • Rapp DE, Turk KW, Bales GT, Cook SP. Botulinum toxin type A inhibits calcitonin gen-related peptide release from isolated rat bladder. J. Urol. 2006; 175: 1138-1142.
    • (2006) J. Urol. , vol.175 , pp. 1138-1142
    • Rapp, D.E.1    Turk, K.W.2    Bales, G.T.3    Cook, S.P.4
  • 59
    • 34548567008 scopus 로고    scopus 로고
    • Synaptobrevin I mediates exocytosis of CGRP from sensory neurons and inhibition by botulinum toxins reflects their anti-nociceptive potential
    • Meng J, Wang J, Lawrence G, Dolly JO. Synaptobrevin I mediates exocytosis of CGRP from sensory neurons and inhibition by botulinum toxins reflects their anti-nociceptive potential. J. Cell Sci. 2007; 120 (Pt 16): 2864-2874.
    • (2007) J. Cell Sci. , vol.120 , Issue.PART 16 , pp. 2864-2874
    • Meng, J.1    Wang, J.2    Lawrence, G.3    Dolly, J.O.4
  • 60
    • 37849009378 scopus 로고    scopus 로고
    • Botulinum toxin type A inhibits sensory neuropeptide release in rat bladder models of acute injury and chronic inflammation
    • Lucioni A, Bales GT, Lotan TL, McGehee DS, Cook SP, Rapp DE. Botulinum toxin type A inhibits sensory neuropeptide release in rat bladder models of acute injury and chronic inflammation. BJU Int. 2008; 101: 366-370.
    • (2008) BJU Int. , vol.101 , pp. 366-370
    • Lucioni, A.1    Bales, G.T.2    Lotan, T.L.3    McGehee, D.S.4    Cook, S.P.5    Rapp, D.E.6
  • 61
    • 4444289380 scopus 로고    scopus 로고
    • Botulinum toxin A inhibits ATP release from bladder urothelium after chronic spinal cord injury
    • Khera M, Somogyi GT, Kiss S, Boone TB, Smith CP. Botulinum toxin A inhibits ATP release from bladder urothelium after chronic spinal cord injury. Neurochem. Int. 2004; 45: 987-993.
    • (2004) Neurochem. Int. , vol.45 , pp. 987-993
    • Khera, M.1    Somogyi, G.T.2    Kiss, S.3    Boone, T.B.4    Smith, C.P.5
  • 62
    • 41249102189 scopus 로고    scopus 로고
    • Botulinum toxin type A normalizes alterations in urothelial ATP and NO release induced by chronic spinal cord injury
    • Smith CP, Gangiano DA, Munoz A etal. Botulinum toxin type A normalizes alterations in urothelial ATP and NO release induced by chronic spinal cord injury. Neurochem. Int. 2008; 52: 1068-1075.
    • (2008) Neurochem. Int. , vol.52 , pp. 1068-1075
    • Smith, C.P.1    Gangiano, D.A.2    Munoz, A.3
  • 63
    • 23744514242 scopus 로고    scopus 로고
    • Decreased sensory receptors P2X3 and TRPV1 in suburothelial nerve fibers following intradetrusor injections of botulinum toxin for human detrusor overactivity
    • discussion 982-3.
    • Apostolidis A, Popta R, Yiangou Y etal. Decreased sensory receptors P2X3 and TRPV1 in suburothelial nerve fibers following intradetrusor injections of botulinum toxin for human detrusor overactivity. J. Urol. 2005; 174: 977-982; discussion 982-3.
    • (2005) J. Urol. , vol.174 , pp. 977-982
    • Apostolidis, A.1    Popta, R.2    Yiangou, Y.3
  • 64
    • 78349307168 scopus 로고    scopus 로고
    • Immunohistochemial exression of muscarinic receptors in the urothelium and suburothelium of neurogenic and idiopathic overactive human bladders, and changes with botulinum neurotoxin administration
    • Datta SN, Roosen A, Oullen A etal. Immunohistochemial exression of muscarinic receptors in the urothelium and suburothelium of neurogenic and idiopathic overactive human bladders, and changes with botulinum neurotoxin administration. J. Urol. 2010; 184: 2578-2585.
    • (2010) J. Urol. , vol.184 , pp. 2578-2585
    • Datta, S.N.1    Roosen, A.2    Oullen, A.3
  • 65
    • 80052264107 scopus 로고    scopus 로고
    • Contemporary management of lower urinary tract disease with botulinum toxin A: a systematic review of botox (onabotulinumtoxinA) and dysport (abobotulinumtoxinA)
    • Mangera A, Andersson KE, Apostolidis A etal. Contemporary management of lower urinary tract disease with botulinum toxin A: a systematic review of botox (onabotulinumtoxinA) and dysport (abobotulinumtoxinA). Eur. Urol. 2011; 60: 784-795.
    • (2011) Eur. Urol. , vol.60 , pp. 784-795
    • Mangera, A.1    Andersson, K.E.2    Apostolidis, A.3
  • 66
    • 34248208099 scopus 로고    scopus 로고
    • Efficacy of botulinum toxin A for treating idiopathic detrusor overactivity: results from a single center, randomized, double-blind, placebo controlled trial
    • Sahai A, Khan MS, Dasgupta P. Efficacy of botulinum toxin A for treating idiopathic detrusor overactivity: results from a single center, randomized, double-blind, placebo controlled trial. J. Urol. 2007; 177: 2231-2236.
    • (2007) J. Urol. , vol.177 , pp. 2231-2236
    • Sahai, A.1    Khan, M.S.2    Dasgupta, P.3
  • 67
    • 46549084672 scopus 로고    scopus 로고
    • Refractory idiopathic urge urinary incontinence and botulinum A injection
    • Brubaker L, Richter HE, Visco A etal. Refractory idiopathic urge urinary incontinence and botulinum A injection. J. Urol. 2008; 180: 217-222.
    • (2008) J. Urol. , vol.180 , pp. 217-222
    • Brubaker, L.1    Richter, H.E.2    Visco, A.3
  • 68
    • 84863720769 scopus 로고    scopus 로고
    • Botulinum toxin A versus placebo for refractory detrusor overactivity in women: a randomized blinded placebo-controlled trial of 240 women (the RELAX study)
    • Tincello DG, Kenyon S, Abrams KR etal. Botulinum toxin A versus placebo for refractory detrusor overactivity in women: a randomized blinded placebo-controlled trial of 240 women (the RELAX study). Eur. Urol. 2012; 62: 507-514.
    • (2012) Eur. Urol. , vol.62 , pp. 507-514
    • Tincello, D.G.1    Kenyon, S.2    Abrams, K.R.3
  • 69
    • 79954603137 scopus 로고    scopus 로고
    • Urodynamic results and clinical outcomes with intradetrusor injections of onabotulinumtoxinA in a randomized, placebo-controlled dose-finding study in idiopathic overactive bladder
    • Rovner E, Kennelly M, Schulte-Baukloh H, Zhou J, Haag-Molkenteller C, Dasgupta P. Urodynamic results and clinical outcomes with intradetrusor injections of onabotulinumtoxinA in a randomized, placebo-controlled dose-finding study in idiopathic overactive bladder. Neurourol. Urodyn. 2011; 30: 556-562.
    • (2011) Neurourol. Urodyn. , vol.30 , pp. 556-562
    • Rovner, E.1    Kennelly, M.2    Schulte-Baukloh, H.3    Zhou, J.4    Haag-Molkenteller, C.5    Dasgupta, P.6
  • 70
    • 84861126467 scopus 로고    scopus 로고
    • Role of botulinum toxin-A in refractory idiopathic overactive bladder patients without detrusor overactivity
    • Kanagarajah P, Ayyathurai R, Caruso DJ, Gomez C, Gousse AE. Role of botulinum toxin-A in refractory idiopathic overactive bladder patients without detrusor overactivity. Int. Urol. Nephrol. 2012; 44: 91-97.
    • (2012) Int. Urol. Nephrol. , vol.44 , pp. 91-97
    • Kanagarajah, P.1    Ayyathurai, R.2    Caruso, D.J.3    Gomez, C.4    Gousse, A.E.5
  • 71
    • 78349305456 scopus 로고    scopus 로고
    • Efficacy and safety of onabotulinumtoxin A for idiopathic overactive bladder: a double-blind, placebo controlled, randomized, dose ranging trial
    • Dmochowski R, Chapple C, Nitti VW etal. Efficacy and safety of onabotulinumtoxin A for idiopathic overactive bladder: a double-blind, placebo controlled, randomized, dose ranging trial. J. Urol. 2010; 184: 2416-2422.
    • (2010) J. Urol. , vol.184 , pp. 2416-2422
    • Dmochowski, R.1    Chapple, C.2    Nitti, V.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.