-
1
-
-
9244234710
-
Pharmacology of the lower urinary tract: Basis for current and future treatments of urinary incontinence
-
Andersson KE, Wein AJ. Pharmacology of the lower urinary tract: basis for current and future treatments of urinary incontinence. Pharmacol Rev 2004; 56: 581-631
-
(2004)
Pharmacol Rev
, vol.56
, pp. 581-631
-
-
Andersson, K.E.1
Wein, A.J.2
-
2
-
-
0034997781
-
Neurotransmission and drug effects in urethral smooth muscle
-
Andersson KE. Neurotransmission and drug effects in urethral smooth muscle. Scand J Urol Nephrol Suppl 2001; 207: 26-34
-
(2001)
Scand J Urol Nephrol Suppl
, vol.207
, pp. 26-34
-
-
Andersson, K.E.1
-
3
-
-
0035188826
-
Cyclic nucleotide phosphodiesterases
-
Essayan DM. Cyclic nucleotide phosphodiesterases. J Allergy Clin Immunol 2001; 108: 671-80
-
(2001)
J Allergy Clin Immunol
, vol.108
, pp. 671-680
-
-
Essayan, D.M.1
-
4
-
-
0029933970
-
Cyclic nucleotide phosphodiesterase (PDE) isoenzymes in the human detrusor smooth muscle. I. Identification and characterization
-
Truss MC, Uckert S, Stief CG, Kuczyk M, Jonas U. Cyclic nucleotide phosphodiesterase (PDE) isoenzymes in the human detrusor smooth muscle. I. Identification and characterization. Urol Res 1996; 24: 123-8
-
(1996)
Urol Res
, vol.24
, pp. 123-128
-
-
Truss, M.C.1
Uckert, S.2
Stief, C.G.3
Kuczyk, M.4
Jonas, U.5
-
5
-
-
0028846996
-
Porcine detrusor cyclic nucleotide phosphodiesterase isoenzymes: Characterization and functional effects of various phosphodiesterase inhibitors in vitro
-
Truss MC, Uckert S, Stief CG et al. Porcine detrusor cyclic nucleotide phosphodiesterase isoenzymes: characterization and functional effects of various phosphodiesterase inhibitors in vitro. Urology 1995; 45: 893-901
-
(1995)
Urology
, vol.45
, pp. 893-901
-
-
Truss, M.C.1
Uckert, S.2
Stief, C.G.3
-
6
-
-
0035174618
-
Characterization and functional relevance of cyclic nucleotide phosphodiesterase isoenzymes of the human prostate
-
Uckert S, Kuthe A, Jonas U, Stief CG. Characterization and functional relevance of cyclic nucleotide phosphodiesterase isoenzymes of the human prostate. J Urol 2001; 166: 2484-90
-
(2001)
J Urol
, vol.166
, pp. 2484-2490
-
-
Uckert, S.1
Kuthe, A.2
Jonas, U.3
Stief, C.G.4
-
7
-
-
31144460516
-
Phosphodiesterase inhibitors in female sexual dysfunction
-
Mayer M, Stief CG, Truss MC, Uckert S. Phosphodiesterase inhibitors in female sexual dysfunction. World J Urol 2005; 23: 393-7
-
(2005)
World J Urol
, vol.23
, pp. 393-397
-
-
Mayer, M.1
Stief, C.G.2
Truss, M.C.3
Uckert, S.4
-
8
-
-
15244344073
-
Cyclic adenosine monophosphate and cyclic guanosine monophosphate- phosphodiesterase isoenzymes in human vagina: Relation to nitric oxide synthase isoforms and vasoactive intestinal polypeptide-containing nerves
-
Uckert S, Oelke M, Waldkirch E et al. Cyclic adenosine monophosphate and cyclic guanosine monophosphate-phosphodiesterase isoenzymes in human vagina: relation to nitric oxide synthase isoforms and vasoactive intestinal polypeptide-containing nerves. Urology 2005; 65: 604-10
-
(2005)
Urology
, vol.65
, pp. 604-610
-
-
Uckert, S.1
Oelke, M.2
Waldkirch, E.3
-
9
-
-
0035512476
-
Phosphodiesterase 1 inhibition in the treatment of lower urinary tract dysfunction: From bench to bedside
-
Truss MC, Stief CG, Uckert S et al. Phosphodiesterase 1 inhibition in the treatment of lower urinary tract dysfunction: from bench to bedside. World J Urol 2001; 19: 344-50
-
(2001)
World J Urol
, vol.19
, pp. 344-350
-
-
Truss, M.C.1
Stief, C.G.2
Uckert, S.3
-
10
-
-
0025921705
-
NG-nitro-L-arginine inhibits non-adrenergic, non-cholinergic relaxation in rabbit urethral smooth muscle
-
Dokita S, Morgan WR, Wheeler MA, Yoshida M, Latifpour J, Weiss RM. NG-nitro-L-arginine inhibits non-adrenergic, non-cholinergic relaxation in rabbit urethral smooth muscle. Life Sci 1991; 48: 2429-36
-
(1991)
Life Sci
, vol.48
, pp. 2429-2436
-
-
Dokita, S.1
Morgan, W.R.2
Wheeler, M.A.3
Yoshida, M.4
Latifpour, J.5
Weiss, R.M.6
-
11
-
-
0028169071
-
Non-adrenergic, non-cholinergic relaxation and levels of cyclic nucleotides in rabbit lower urinary tract
-
Persson K, Andersson KE. Non-adrenergic, non-cholinergic relaxation and levels of cyclic nucleotides in rabbit lower urinary tract. Eur J Pharmacol 1994; 268: 159-67
-
(1994)
Eur J Pharmacol
, vol.268
, pp. 159-167
-
-
Persson, K.1
Andersson, K.E.2
-
12
-
-
0030154874
-
Sildenafil: An orally active type 5 cyclic GMP-specific phosphodiesterase inhibitor for the treatment of penile erectile dysfunction
-
Boolell M, Allen MJ, Ballard SA et al. Sildenafil: an orally active type 5 cyclic GMP-specific phosphodiesterase inhibitor for the treatment of penile erectile dysfunction. Int J Impot Res 1996; 8: 47-52
-
(1996)
Int J Impot Res
, vol.8
, pp. 47-52
-
-
Boolell, M.1
Allen, M.J.2
Ballard, S.A.3
-
13
-
-
0141992797
-
The discovery of tadalafil: A novel and highly selective PDE5 inhibitor. 1: 5,6,11,11a-tetrahydro-1H-imidazo[1′,5′:1,6]pyrido[3,4-b]indole-1, 3 (2H)-dione analogues
-
Daugan A, Grondin P, Ruault C et al. The discovery of tadalafil: a novel and highly selective PDE5 inhibitor. 1: 5,6,11,11a-tetrahydro-1H- imidazo[1′,5′:1,6]pyrido[3,4-b]indole-1,3 (2H)-dione analogues. J Med Chem 2003; 46: 4525-32
-
(2003)
J Med Chem
, vol.46
, pp. 4525-4532
-
-
Daugan, A.1
Grondin, P.2
Ruault, C.3
-
14
-
-
0035157613
-
The phosphodiesterase inhibitory selectivity and the in vitro and in vivo potency of the new PDE5 inhibitor vardenafil
-
Saenz de Tejada I, Angulo J, Cuevas P et al. The phosphodiesterase inhibitory selectivity and the in vitro and in vivo potency of the new PDE5 inhibitor vardenafil. Int J Impot Res 2001; 13: 282-90
-
(2001)
Int J Impot Res
, vol.13
, pp. 282-290
-
-
Saenz De Tejada, I.1
Angulo, J.2
Cuevas, P.3
-
15
-
-
0036883918
-
Sildenafil influences lower urinary tract symptoms
-
Sairam K, Kulinskaya E, McNicholas TA, Boustead GB, Hanbury DC. Sildenafil influences lower urinary tract symptoms. BJU Int 2002; 90: 836-9
-
(2002)
BJU Int
, vol.90
, pp. 836-839
-
-
Sairam, K.1
Kulinskaya, E.2
McNicholas, T.A.3
Boustead, G.B.4
Hanbury, D.C.5
-
16
-
-
0029089944
-
Factors involved in the relaxation of female pig urethra evoked by electrical field stimulation
-
Werkström V, Persson K, Ny L, Bridgewater M, Brading AF, Andersson KE. Factors involved in the relaxation of female pig urethra evoked by electrical field stimulation. Br J Pharmacol 1995; 116: 1599-604
-
(1995)
Br J Pharmacol
, vol.116
, pp. 1599-1604
-
-
Werkström, V.1
Persson, K.2
Ny, L.3
Bridgewater, M.4
Brading, A.F.5
Andersson, K.E.6
-
17
-
-
0032567131
-
Inhibitory innervation of the guinea-pig urethra; roles of CO, NO and VIP
-
Werkström V, Alm P, Persson K, Andersson KE. Inhibitory innervation of the guinea-pig urethra; roles of CO, NO and VIP. J Auton Nerv Syst 1998; 74: 33-42
-
(1998)
J Auton Nerv Syst
, vol.74
, pp. 33-42
-
-
Werkström, V.1
Alm, P.2
Persson, K.3
Andersson, K.E.4
-
18
-
-
0030021277
-
Distribution of nitric oxide synthase-immunoreactive nerves and identification of the cellular targets of nitric oxide in guinea-pig and human urinary bladder by cGMP immunohistochemistry
-
Smet PJ, Jonavicius J, Marshall VR, de Vente J. Distribution of nitric oxide synthase-immunoreactive nerves and identification of the cellular targets of nitric oxide in guinea-pig and human urinary bladder by cGMP immunohistochemistry. Neuroscience 1996; 71: 337-48
-
(1996)
Neuroscience
, vol.71
, pp. 337-348
-
-
Smet, P.J.1
Jonavicius, J.2
Marshall, V.R.3
De Vente, J.4
-
19
-
-
9644272419
-
cGMP-generating cells in the bladder wall: Identification of distinct networks of interstitial cells
-
Gillespie JI, Markerink-van Ittersum M, de Vente J. cGMP-generating cells in the bladder wall: identification of distinct networks of interstitial cells. BJU Int 2004; 94: 1114-24
-
(2004)
BJU Int
, vol.94
, pp. 1114-1124
-
-
Gillespie, J.I.1
Markerink-van Ittersum, M.2
De Vente, J.3
-
21
-
-
0034661464
-
Specialised pacemaking cells in the rabbit urethra
-
Sergeant GP, Hollywood MA, McCloskey KD, Thornbury KD, McHale NG. Specialised pacemaking cells in the rabbit urethra. J Physiol 2000; 526: 359-66
-
(2000)
J Physiol
, vol.526
, pp. 359-366
-
-
Sergeant, G.P.1
Hollywood, M.A.2
McCloskey, K.D.3
Thornbury, K.D.4
McHale, N.G.5
-
22
-
-
0031016768
-
Carbon monoxide-induced relaxation and distribution of haem oxygenase isoenzymes in the pig urethra and oesophagogastric junction
-
Werkström V, Ny L, Persson K, Andersson KE. Carbon monoxide-induced relaxation and distribution of haem oxygenase isoenzymes in the pig urethra and oesophagogastric junction. Br J Pharmacol 1997; 120: 312-8
-
(1997)
Br J Pharmacol
, vol.120
, pp. 312-318
-
-
Werkström, V.1
Ny, L.2
Persson, K.3
Andersson, K.E.4
-
23
-
-
0036129642
-
Carbon monoxide relaxes the female pig urethra as effectively as nitric oxide in the presence of YC-1
-
Schroder A, Hedlund P, Andersson KE. Carbon monoxide relaxes the female pig urethra as effectively as nitric oxide in the presence of YC-1. J Urol 2002; 167: 1892-6
-
(2002)
J Urol
, vol.167
, pp. 1892-1896
-
-
Schroder, A.1
Hedlund, P.2
Andersson, K.E.3
-
24
-
-
0031056182
-
Age-dependent changes in particulate and soluble guanylyl cyclase activities in urinary tract smooth muscle
-
Wheeler MA, Pontari M, Dokita S et al. Age-dependent changes in particulate and soluble guanylyl cyclase activities in urinary tract smooth muscle. Mol Cell Biochem 1997; 169: 115-24
-
(1997)
Mol Cell Biochem
, vol.169
, pp. 115-124
-
-
Wheeler, M.A.1
Pontari, M.2
Dokita, S.3
-
25
-
-
0033958337
-
Effects of sildenafil on cAMP and cGMP levels in isolated human cavernous and cardiac tissue
-
Stief CG, Uckert S, Becker AJ et al. Effects of sildenafil on cAMP and cGMP levels in isolated human cavernous and cardiac tissue. Urology 2000; 55: 146-50
-
(2000)
Urology
, vol.55
, pp. 146-150
-
-
Stief, C.G.1
Uckert, S.2
Becker, A.J.3
-
26
-
-
0031403328
-
Effects of sildenafil, a type-5 cGMP phosphodiesterase inhibitor, and papaverine on cyclic GMP and cyclic AMP levels in the rabbit corpus cavernosum in vitro
-
Jeremy JY, Ballard SA, Naylor AM, Miller MA, Angelini GD. Effects of sildenafil, a type-5 cGMP phosphodiesterase inhibitor, and papaverine on cyclic GMP and cyclic AMP levels in the rabbit corpus cavernosum in vitro. Br J Urol 1997; 79: 958-63
-
(1997)
Br J Urol
, vol.79
, pp. 958-963
-
-
Jeremy, J.Y.1
Ballard, S.A.2
Naylor, A.M.3
Miller, M.A.4
Angelini, G.D.5
-
27
-
-
4043052350
-
Relaxant action of sildenafil citrate (Viagra) on human myometrium of pregnancy
-
Khan RN, Hamoud H, Warren A, Wong LF, Arulkumaran S. Relaxant action of sildenafil citrate (Viagra) on human myometrium of pregnancy. Am J Obstet Gynecol 2004; 191: 315-21
-
(2004)
Am J Obstet Gynecol
, vol.191
, pp. 315-321
-
-
Khan, R.N.1
Hamoud, H.2
Warren, A.3
Wong, L.F.4
Arulkumaran, S.5
-
28
-
-
0033677435
-
Inhibition of neuroeffector transmission in human vas deferens by sildenafil
-
Medina P, Segarra G, Torondel B et al. Inhibition of neuroeffector transmission in human vas deferens by sildenafil. Br J Pharmacol 2000; 131: 871-4
-
(2000)
Br J Pharmacol
, vol.131
, pp. 871-874
-
-
Medina, P.1
Segarra, G.2
Torondel, B.3
-
29
-
-
13844256288
-
Sildenafil prevents endothelial dysfunction induced by ischemia and reperfusion via opening of adenosine triphosphate-sensitive potassium channels: A human in vivo study
-
Gori T, Sicuro S, Dragoni S, Donati G, Forconi S, Parker JD. Sildenafil prevents endothelial dysfunction induced by ischemia and reperfusion via opening of adenosine triphosphate-sensitive potassium channels: a human in vivo study. Circulation 2005; 111: 742-6
-
(2005)
Circulation
, vol.111
, pp. 742-746
-
-
Gori, T.1
Sicuro, S.2
Dragoni, S.3
Donati, G.4
Forconi, S.5
Parker, J.D.6
-
30
-
-
3042574999
-
Binding of tritiated sildenafil, tadalafil, or vardenafil to the phosphodiesterase-5 catalytic site displays potency, specificity, heterogeneity, and cGMP stimulation
-
Blount MA, Beasley A, Zoraghi R et al. Binding of tritiated sildenafil, tadalafil, or vardenafil to the phosphodiesterase-5 catalytic site displays potency, specificity, heterogeneity, and cGMP stimulation. Mol Pharmacol 2004; 66: 144-52
-
(2004)
Mol Pharmacol
, vol.66
, pp. 144-152
-
-
Blount, M.A.1
Beasley, A.2
Zoraghi, R.3
-
31
-
-
4243194585
-
Vardenafil: Structural basis for higher potency over sildenafil in inhibiting cGMP-specific phosphodiesterase-5 (PDE5)
-
Corbin JD, Beasley A, Blount MA, Francis SH. Vardenafil: structural basis for higher potency over sildenafil in inhibiting cGMP-specific phosphodiesterase-5 (PDE5). Neurochem Int 2004; 45: 859-63
-
(2004)
Neurochem Int
, vol.45
, pp. 859-863
-
-
Corbin, J.D.1
Beasley, A.2
Blount, M.A.3
Francis, S.H.4
-
32
-
-
0026549628
-
Nitric oxide and relaxation of pig lower urinary tract
-
Persson K, Andersson KE. Nitric oxide and relaxation of pig lower urinary tract. Br J Pharmacol 1992; 106: 416-22
-
(1992)
Br J Pharmacol
, vol.106
, pp. 416-422
-
-
Persson, K.1
Andersson, K.E.2
-
33
-
-
0028882434
-
Characteristics of the NANC post-stimulus ('rebound') contraction of the urinary bladder neck muscle in sheep
-
Thornbury KD, Donaghy KM, Peake J. Characteristics of the NANC post-stimulus ('rebound') contraction of the urinary bladder neck muscle in sheep. Br J Pharmacol 1995; 116: 2451-6
-
(1995)
Br J Pharmacol
, vol.116
, pp. 2451-2456
-
-
Thornbury, K.D.1
Donaghy, K.M.2
Peake, J.3
-
35
-
-
0036016111
-
An investigation of the effects of zaprinast, a PDE inhibitor, on the nitrergic control of the urethra in anaesthetized female rats
-
Wibberley A, Nunn PA, Naylor AM, Ramage AG. An investigation of the effects of zaprinast, a PDE inhibitor, on the nitrergic control of the urethra in anaesthetized female rats. Br J Pharmacol 2002; 136: 399-414
-
(2002)
Br J Pharmacol
, vol.136
, pp. 399-414
-
-
Wibberley, A.1
Nunn, P.A.2
Naylor, A.M.3
Ramage, A.G.4
-
36
-
-
0030915371
-
Urinary bladder-urethral sphincter dysfunction in mice with targeted disruption of neuronal nitric oxide synthase models idiopathic voiding disorders in humans
-
Burnett AL, Calvin DC, Chamness SL et al. Urinary bladder-urethral sphincter dysfunction in mice with targeted disruption of neuronal nitric oxide synthase models idiopathic voiding disorders in humans. Nat Med 1997; 3: 571-4
-
(1997)
Nat Med
, vol.3
, pp. 571-574
-
-
Burnett, A.L.1
Calvin, D.C.2
Chamness, S.L.3
-
37
-
-
0033834014
-
Functional characteristics of urinary tract smooth muscles in mice lacking cGMP protein kinase type I
-
Persson K, Pandita RK, Aszodi A et al. Functional characteristics of urinary tract smooth muscles in mice lacking cGMP protein kinase type I. Am J Physiol Regul Integr Comp Physiol 2000; 279: R1112-20
-
(2000)
Am J Physiol Regul Integr Comp Physiol
, vol.279
-
-
Persson, K.1
Pandita, R.K.2
Aszodi, A.3
-
38
-
-
0032855602
-
Alterations in the nitric oxide synthase binding sites and non-adrenergic, non-cholinergic mediated smooth muscle relaxation in the diabetic rabbit bladder outlet: Possible relevance to the pathogenesis of diabetic cystopathy
-
Mumtaz FH, Sullivan ME, Thompson CS et al. Alterations in the nitric oxide synthase binding sites and non-adrenergic, non-cholinergic mediated smooth muscle relaxation in the diabetic rabbit bladder outlet: possible relevance to the pathogenesis of diabetic cystopathy. J Urol 1999; 162: 558-66
-
(1999)
J Urol
, vol.162
, pp. 558-566
-
-
Mumtaz, F.H.1
Sullivan, M.E.2
Thompson, C.S.3
-
39
-
-
0033403043
-
Alterations in the formation of cyclic nucleotides and prostaglandins in the lower urinary tract of the diabetic rabbit
-
Mumtaz FH, Thompson CS, Khan MA et al. Alterations in the formation of cyclic nucleotides and prostaglandins in the lower urinary tract of the diabetic rabbit. Urol Res 1999; 27: 470-5
-
(1999)
Urol Res
, vol.27
, pp. 470-475
-
-
Mumtaz, F.H.1
Thompson, C.S.2
Khan, M.A.3
-
40
-
-
0034987458
-
Involvement of accumulated endogenous NOS inhibitors and decreased NOS activity in the impaired neurogenic relaxation of the rabbit proximal urethra with ischaemia
-
Masuda H, Tsujii T, Okuno T, Kihara K, Goto M, Azuma H. Involvement of accumulated endogenous NOS inhibitors and decreased NOS activity in the impaired neurogenic relaxation of the rabbit proximal urethra with ischaemia. Br J Pharmacol 2001; 133: 97-106
-
(2001)
Br J Pharmacol
, vol.133
, pp. 97-106
-
-
Masuda, H.1
Tsujii, T.2
Okuno, T.3
Kihara, K.4
Goto, M.5
Azuma, H.6
-
41
-
-
0032712151
-
Vesicourethral function in diabetic patients: Association of abnormal nerve conduction velocity with vesicourethral dysfunction
-
Mitsui T, Kakizaki H, Kobayashi S, Morita H, Matsumura K, Koyanagi T. Vesicourethral function in diabetic patients: association of abnormal nerve conduction velocity with vesicourethral dysfunction. Neurourol Urodyn 1999; 18: 639-45
-
(1999)
Neurourol Urodyn
, vol.18
, pp. 639-645
-
-
Mitsui, T.1
Kakizaki, H.2
Kobayashi, S.3
Morita, H.4
Matsumura, K.5
Koyanagi, T.6
-
42
-
-
0027296453
-
Nitric oxide synthase in pig lower urinary tract: Immunohistochemistry, NADPH diaphorase histochemistry and functional effects
-
Persson K, Alm P, Johansson K, Larsson B, Andersson KE. Nitric oxide synthase in pig lower urinary tract: immunohistochemistry, NADPH diaphorase histochemistry and functional effects. Br J Pharmacol 1993; 110: 521-30
-
(1993)
Br J Pharmacol
, vol.110
, pp. 521-530
-
-
Persson, K.1
Alm, P.2
Johansson, K.3
Larsson, B.4
Andersson, K.E.5
|