Miniaturized flow cytometric in vitro micronucleus assay represents an efficient tool for comprehensively characterizing genotoxicity dose-response relationships

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 703, Issue 2, 2010, Pages 191-199

  Bryce, Steven M ^a   Avlasevich, Svetlana L ^a   Bemis, Jeffrey C ^a   Phonethepswath, Souk ^a   Dertinger, Stephen D ^a  

^a LITRON LABORATORIES   (United States)

Author keywords

Flow cytometry; Genotoxicity; Micronuclei; Risk assessment; Threshold; TK6 cells

Indexed keywords

ALKYLATING AGENT; ANEUGEN; BLEOMYCIN; COLCHICINE; ETHYLNITROSOUREA; MESYLIC ACID ETHYL ESTER; MESYLIC ACID METHYL ESTER; METHYLNITROSOUREA; VINBLASTINE SULFATE;

ARTICLE; CELL DIVISION; CONTROLLED STUDY; DOSE RESPONSE; FLOW CYTOMETRY; GENOTOXICITY; HUMAN; HUMAN CELL; IN VITRO STUDY; MICRONUCLEUS TEST; PRIORITY JOURNAL;

CELL LINE; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; FLOW CYTOMETRY; HUMANS; MICRONUCLEUS TESTS; MUTAGENS;

EID: 78549250674     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2010.08.020     Document Type: Article

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