Identification of the Molecular Site of Ivabradine Binding to HCN4 Channels

PLoS ONE

Volumn 8, Issue 1, 2013, Pages

  Bucchi, Annalisa ^a   Baruscotti, Mirko ^a   Nardini, Marco ^a   Barbuti, Andrea ^a   Micheloni, Stefano ^a   Bolognesi, Martino ^a   DiFrancesco, Dario ^a  

^a UNIVERSITY OF MILAN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

HCN4 CHANNEL; ION CHANNEL; IVABRADINE; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; COMPUTER MODEL; CONTROLLED STUDY; DRUG PROTEIN BINDING; HUMAN; HUMAN CELL; HYDROPHOBICITY; MOLECULAR DOCKING; MUTAGENESIS; PROTEIN EXPRESSION; PROTEIN STRUCTURE; SENSITIVITY ANALYSIS; SEQUENCE HOMOLOGY; VOLTAGE CLAMP; X RAY ANALYSIS;

AMINO ACID SEQUENCE; BENZAZEPINES; BINDING SITES; CYCLIC NUCLEOTIDE-GATED CATION CHANNELS; HEK293 CELLS; HUMANS; MOLECULAR DOCKING SIMULATION; MOLECULAR SEQUENCE DATA; MUSCLE PROTEINS; POINT MUTATION; SEQUENCE ALIGNMENT; SINOATRIAL NODE;

ANGINA;

EID: 84871868714     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0053132     Document Type: Article

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