Comparative analysis of sample preparation methods to handle the complexity of the blood fluid metabolome: When less is more

Analytical Chemistry

Volumn 85, Issue 1, 2013, Pages 341-348

  Tulipani, Sara ^a,b   Llorach, Rafael ^a,b   Urpi Sarda, Mireia ^a,b   Andres Lacueva, Cristina ^a,b  

^a UNIVERSITY OF BARCELONA   (Spain)

^b Ministry of Science and Innovation   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ANALYTICAL PROCEDURE; BIOLOGICAL VARIATION; BLOOD SAMPLES; COMPARATIVE ANALYSIS; DEPROTEINIZATION; ENDOGENOUS COMPOUND; ERROR PRONES; EXTRACTION PROCEDURE; HYBRID METHOD; INFORMATION COVERAGE; ION SUPPRESSION; LOW-MOLECULAR-WEIGHT SPECIES; MATRIX EFFECTS; METABOLOMES; METABOLOMIC ANALYSIS; METABOLOMIC STUDY; METABOLOMICS; PREPARATION METHOD; REPRODUCIBILITIES; SAMPLE HANDLING; SAMPLE PREPARATION; SAMPLE PREPARATION METHODS; SAMPLE PREPARATION PROCEDURE; SAMPLE PREPARATION TECHNIQUES; SELECTIVE REMOVAL; SERUM SAMPLES; SOLVENT FREE; SPIKED SAMPLES;

ACETONITRILE; BIOMOLECULES; BLOOD; DIGITAL STORAGE; METABOLITES; METHANOL; PHOSPHOLIPIDS; SAMPLING; SOLVENT EXTRACTION; ULTRAFILTRATION;

ORGANIC SOLVENTS;

ACETONITRILE; ACETONITRILE DERIVATIVE; ALCOHOL; METHANOL; PHOSPHOLIPID;

ARTICLE; BODY FLUID; CACAO; CHEMISTRY; COMPARATIVE STUDY; ELECTROSPRAY MASS SPECTROMETRY; FRACTIONATION; HUMAN; METABOLISM; METABOLOME; SOLID PHASE EXTRACTION; ULTRAFILTRATION;

ACETONITRILES; BODY FLUIDS; CACAO; CHEMICAL FRACTIONATION; ETHANOL; HUMANS; METABOLOME; METHANOL; PHOSPHOLIPIDS; SOLID PHASE EXTRACTION; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; ULTRAFILTRATION;

EID: 84871784197     PISSN: 00032700     EISSN: 15206882     Source Type: Journal    
DOI: 10.1021/ac302919t     Document Type: Article

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