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Volumn 4, Issue 1, 2013, Pages 95-100

Optimisation of aqueous solubility in a series of G protein coupled receptor 119 (GPR119) agonists

(13) Scott, James S a Birch, Alan M a Brocklehurst, Katy J a Brown, Hayley S a Goldberg, Kristin a Groombridge, Sam D a Hudson, Julian A a Leach, Andrew G a MacFaul, Philip A a McKerrecher, Darren a Poultney, Ruth a Schofield, Paul a Svensson, Per H b

a ASTRAZENECA (United Kingdom)

b ROYAL INSTITUTE OF TECHNOLOGY (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIDIABETIC AGENT; CARBAMIC ACID DERIVATIVE; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR 119; G PROTEIN COUPLED RECEPTOR 119 AGONIST; OXADIAZOLE DERIVATIVE; SULFONE DERIVATIVE; TRIFUOROMETHYL OXETANE; UNCLASSIFIED DRUG;

AQUEOUS SOLUBILITY; ARTICLE; CONTROLLED STUDY; DRUG INTERACTION; DRUG METABOLISM; DRUG POTENCY; DRUG SOLUBILITY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HYDROGEN BOND; LIPOPHILICITY; NONHUMAN; PH; PRIORITY JOURNAL; SOLID STATE; X RAY CRYSTALLOGRAPHY;

EID: 84871765871 PISSN: 20402503 EISSN: 20402511 Source Type: Journal
DOI: 10.1039/c2md20130e Document Type: Article

Times cited : (15)

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