2,5-Disubstituted pyridines as potent GPR119 agonists

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 8, 2010, Pages 2577-2581

  Wu, Yulin ^a   Kuntz, Judith D ^a   Carpenter, Andrew J ^a   Fang, Jing ^a   Sauls, Howard R ^a   Gomez, Daniel J ^a   Ammala, Carina ^a   Xu, Yun ^a   Hart, Shane ^a   Tadepalli, Sarva ^a  

^a GLAXOSMITHKLINE   (United States)

Author keywords

GPR119 receptor; SAR; Type 2 diabetes

Indexed keywords

G PROTEIN COUPLED RECEPTOR; PIPERAZINE DERIVATIVE; PYRIDINE DERIVATIVE;

ARTICLE; CHEMICAL REACTION; DRUG ACTIVITY; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; STRUCTURE ACTIVITY RELATION;

ANIMALS; HALF-LIFE; HUMANS; MICE; PYRIDINES; RECEPTORS, G-PROTEIN-COUPLED; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 77950062510     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.02.083     Document Type: Article

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