Cyclosporin A impairs the secretion and activity of ADAMTS13 (A disintegrin and metalloprotease with thrombospondin type 1 repeat)

Journal of Biological Chemistry

Volumn 287, Issue 53, 2012, Pages 44361-44371

  Hershko, Klilah ^a   Simhadri, Vijaya L ^a   Blaisdell, Adam ^a   Hunt, Ryan C ^a   Newell, Jordan ^a   Tseng, Sandra C ^a   Hershko, Alon Y ^c   Choi, Jae Won ^b   Sauna, Zuben E ^a   Wu, Andrew ^a   Bram, Richard J ^b   Komar, Anton A ^d   Kimchi Sarfaty, Chava ^a  

^a CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

^b MAYO CLINIC   (United States)

^c MEIR MEDICAL CENTER   (Israel)

^d CLEVELAND STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ISOMERIZATION; PATIENT TREATMENT; PHYSIOLOGY;

CONFORMATIONAL CHANGE; CYCLOPHILIN; CYCLOSPORIN A; DISINTEGRINS; METALLO-PROTEASE; MULTIMERS; PLATELET AGGREGATION; PROTEOLYTIC ACTIVITIES; THROMBOSPONDIN; VON WILLEBRAND FACTOR;

PROTEINS;

CHAPERONE; CYCLOPHILIN B; CYCLOSPORIN A; VON WILLEBRAND FACTOR CLEAVING PROTEINASE;

ANIMAL CELL; ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVITY; ENZYME CONFORMATION; ENZYME DEGRADATION; ENZYME INHIBITION; ENZYME RELEASE; HUMAN; HUMAN CELL; MOLECULAR PATHOLOGY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; STRUCTURE ANALYSIS; THROMBOTIC THROMBOCYTOPENIC PURPURA;

MUS;

EID: 84871751028     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.383968     Document Type: Article

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