Molecular characterization of four ADAMTS13 mutations responsible for congenital thrombotic thrombocytopenic purpura (Upshaw-Schulman syndrome)

Thrombosis and Haemostasis

Volumn 98, Issue 3, 2007, Pages 593-599

  Hommais, Antoine ^a   Rayes, Julie ^a   Houllier, Anne ^a   Obert, Bernadette ^a   Legendre, Paulette ^a   Veyradier, Agnes ^a   Girma, Jean Pierre ^a   Ribba, Anne Sophie ^a  

^a UNIVERSITÉ PARIS SACLAY   (France)

Author keywords

ADAMTS13; Mutations; Recombinant proteins; Thrombotic thrombocytopenic purpura (TTP)

Indexed keywords

PROTEINASE; VON WILLEBRAND FACTOR CLEAVING PROTEINASE;

ANIMAL CELL; ARTICLE; CELL STRAIN COS7; CONTROLLED STUDY; ELECTROPHORESIS; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE MUTATION; HUMAN; HUMAN CELL; MOLECULAR MECHANICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN INTERACTION; PROTEIN SECRETION; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; THROMBOTIC THROMBOCYTOPENIC PURPURA; WILD TYPE;

ADAM PROTEINS; ANIMALS; BINDING SITES; CERCOPITHECUS AETHIOPS; COS CELLS; GENETIC PREDISPOSITION TO DISEASE; HELA CELLS; HUMANS; MUTAGENESIS, SITE-DIRECTED; MUTATION, MISSENSE; PEPTIDE FRAGMENTS; PROTEIN BINDING; PROTEIN FOLDING; PURPURA, THROMBOTIC THROMBOCYTOPENIC; RECOMBINANT PROTEINS; RISK FACTORS; SYNDROME; TRANSFECTION; VON WILLEBRAND FACTOR;

EID: 34548679153     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH07-01-0059     Document Type: Article

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