Associations of human leukocyte antigen-G with resistance and susceptibility to HIV-1 infection in the Pumwani sex worker cohort

AIDS

Volumn 27, Issue 1, 2013, Pages 7-15

  Turk, William J R ^a   Kimani, Joshua ^b,c   Bielawny, Tomasz ^a   Wachihi, Charles ^c   Ball, Terry Blake ^a,b,c   Plummer, Francis A ^a,b   Luo, Ma ^a,b  

^a PUBLIC HEALTH AGENCY OF CANADA   (Canada)

^b UNIVERSITY OF MANITOBA   (Canada)

^c UNIVERSITY OF NAIROBI   (Kenya)

Author keywords

disease association; highly exposed seronegative; HIV 1; human leukocyte antigens G; sequence based typing

Indexed keywords

HLA ANTIGEN CLASS 1; HLA ANTIGEN CLASS 2; HLA G ANTIGEN;

ADULT; ALLELE; ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE PREDISPOSITION; DISEASE RESISTANCE; FEMALE; GENOTYPE; HIGH RISK POPULATION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; IMMUNITY; INFLAMMATION; KAPLAN MEIER METHOD; KENYA; MAJOR CLINICAL STUDY; MOLECULE; PRIORITY JOURNAL; PROSTITUTION; SEQUENCE ANALYSIS; SEROCONVERSION;

ADOLESCENT; ADULT; COHORT STUDIES; DISEASE RESISTANCE; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HIV INFECTIONS; HIV-1; HLA-G ANTIGENS; HUMANS; IMMUNITY, MUCOSAL; IMMUNOHISTOCHEMISTRY; KENYA; POLYMORPHISM, SINGLE NUCLEOTIDE; PROSPECTIVE STUDIES; SEX WORKERS;

EID: 84871611416     PISSN: 02699370     EISSN: 14735571     Source Type: Journal    
DOI: 10.1097/QAD.0b013e32835ab1f2     Document Type: Article

References (99)

1. UNAIDS. AIDS epidemic update: November 2009. Geneva: UNAIDS; 2009.
2. Fowke KR, Nagelkerke NJ, Kimani J, Simonsen JN, Anzala AO, Bwayo JJ, et al. Resistance to HIV-1 infection among persistently seronegative prostitutes in Nairobi, Kenya. Lancet 1996; 348:1347-1351. (Pubitemid 26383775)
3. Plummer FA, Ball TB, Kimani J, Fowke KR. Resistance to HIV-1 infection among highly exposed sex workers in Nairobi: what mediates protection and why does it develop? Immunol Lett 1999; 66:27-34. (Pubitemid 29136815)
4. Rowland-Jones S, Sutton J, Ariyoshi K, Dong T, Gotch F, McAdam S, et al. HIV-specific cytotoxic T-cells in HIVexposed but uninfected Gambian women. Nat Med 1995; 1:59-64.
5. Trachtenberg EA, Erlich HA. A review of the role of the human leukocyte antigen (HLA) system as a host immunogenetic factor influencing HIV transmission and progression to AIDS. In: Korber BT, Brander C, Haynes BF, Koup R, Kuiken C, Moore JP, et al., editors. HIV molecular immunology 2001. Los Alamos, NM: Theoretical Biology and Biophysics Group, Los Alamos National Laboratory; 2001.
6. Pereyra F, Addo MM, Kaufmann DE, Liu Y, Miura T, Rathod A, et al. Genetic and immunologic heterogeneity among persons who control HIV infection in the absence of therapy. J Infect Dis 2008; 197:563-571. (Pubitemid 351321534)
7. Koning FA, Jansen CA, Dekker J, Kaslow RA, Dukers N, van Baarle D, et al. Correlates of resistance to HIV-1 infection in homosexual men with high-risk sexual behaviour. AIDS 2004; 18:1117-1126. (Pubitemid 38738511)
8. Liu R, Paxton WA, Choe S, Ceradini D, Martin SR, Horuk R, et al. Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection. Cell 1996; 86:367-377. (Pubitemid 26272077)
9. Paxton WA, Martin SR, Tse D, O'Brien TR, Skurnick J, Van-Devanter NL, et al. Relative resistance to HIV-1 infection of CD4 lymphocytes from persons who remain uninfected despite multiple high-risk sexual exposure. Nat Med 1996; 2:412-417. (Pubitemid 26191912)
10. Liu H, Hwangbo Y, Holte S, Lee J, Wang C, Kaupp N, et al. Analysis of genetic polymorphisms in CCR5, CCR2, stromal cell-derived factor-1, RANTES, and dendritic cell-specific intercellular adhesion molecule-3-grabbing nonintegrin in seronegative individuals repeatedly exposed to HIV-1. J Infect Dis 2004; 190:1055-1058. (Pubitemid 39186790)
11. Ball TB, Ji H, Kimani J, McLaren P, Marlin C, Hill AV, et al. Polymorphisms in IRF-1 associated with resistance to HIV-1 infection in highly exposed uninfected Kenyan sex workers. AIDS 2007; 21:1091-1101. (Pubitemid 46763279)
12. Balotta C, Bagnarelli P, Violin M, Ridolfo AL, Zhou D, Berlusconi A, et al. Homozygous delta 32 deletion of the CCR-5 chemokine receptor gene in an HIV-1-infected patient. AIDS 1997; 11:F67-71. (Pubitemid 27298084)
13. Becker Y. The molecular mechanism of human resistance to HIV-1 infection in persistently infected individuals: a review, hypothesis and implications. Virus Genes 2005; 31:113-119.
14. Bhattacharya T, Stanton J, Kim EY, Kunstman KJ, Phair JP, Jacobson LP, et al. CCL3L1 and HIV/AIDS susceptibility. Nat Med 2009; 15:1112-1115.
15. Bienzle D, MacDonald KS, Smaill FM, Kovacs C, Baqi M, Courssaris B, et al. Factors contributing to the lack of human immunodeficiency virus type 1 (HIV-1) transmission in HIV-1-discordant partners. J Infect Dis 2000; 182:123-132. (Pubitemid 30497796)
16. Biti R, Ffrench R, Young J, Bennetts B, Stewart G, Liang T. HIV-1 infection in an individual homozygous for the CCR5 deletion allele. Nat Med 1997; 3:252-253. (Pubitemid 27112898)
17. Broliden K, Hinkula J, Devito C, Kiama P, Kimani J, Trabbatoni D, et al. Functional HIV-1 specific IgA antibodies in HIV-1 exposed, persistently IgG seronegative female sex workers. Immunol Lett 2001; 79:29-36. (Pubitemid 32938205)
18. Carrington M, Dean M, Martin MP, O'Brien SJ. Genetics of HIV-1 infection: chemokine receptor CCR5 polymorphism and its consequences. Hum Mol Genet 1999; 8:1939-1945. (Pubitemid 29458672)
19. Devito C, Broliden K, Kaul R, Svensson L, Johansen K, Kiama P, et al. Mucosal and plasma IgA from HIV-1-exposed uninfected individuals inhibit HIV-1 transcytosis across human epithelial cells. J Immunol 2000; 165:5170-5176.
20. Kulkarni PS, Butera ST, Duerr AC. Resistance to HIV-1 infection: lessons learned from studies of highly exposed persistently seronegative (HEPS) individuals. AIDS Rev 2003; 5:87-103. (Pubitemid 36873898)
21. Rowland-Jones SL, Pinheiro S, Kaul R, Hansasuta P, Gillespie G, Dong T, et al. How important is the 'quality' of the cytotoxic T lymphocyte (CTL) response in protection against HIV infection? Immunol Lett 2001; 79:15-20. (Pubitemid 32938203)
22. Tang J, Shelton B, Makhatadze NJ, Zhang Y, Schaen M, Louie LG, et al. Distribution of chemokine receptor CCR2 and CCR5 genotypes and their relative contribution to human immunodeficiency virus type 1 (HIV-1) seroconversion, early HIV-1 RNA concentration in plasma, and later disease progression. J Virol 2002; 76:662-672. (Pubitemid 34033365)
23. Yang C, Li M, Limpakarnjanarat K, Young NL, Hodge T, Butera ST, et al. Polymorphisms in the CCR5 coding and noncoding regions among HIV type 1-exposed, persistently seronegative female sex-workers from Thailand. AIDS Res Hum Retroviruses 2003; 19:661-665. (Pubitemid 37047091)
24. Castelli EC, Mendes-Junior CT, Donadi EA. HLA-G alleles and HLA-G 14 bp polymorphisms in a Brazilian population. Tissue Antigens 2007; 70:62-68. (Pubitemid 46890284)
25. Castelli EC, Mendes-Junior CT, Deghaide NH, de Albuquerque RS, Muniz YC, Simoes RT, et al. The genetic structure of 3'untranslated region of the HLA-G gene: polymorphisms and haplotypes. Genes Immun 2010; 11:134-141.
26. Chen XY, Yan WH, Lin A, Xu HH, Zhang JG, Wang XX. The 14 bp deletion polymorphisms in HLA-G gene play an important role in the expression of soluble HLA-G in plasma. Tissue Antigens 2008; 72:335-341.
27. Colobran R, Adreani P, Ashhab Y, Llano A, Este JA, Dominguez O, et al. Multiple products derived from two CCL4 loci: high incidence of a new polymorphism in HIVR patients. J Immunol 2005; 174:5655-5664. (Pubitemid 40593207)
28. Duggal P, An P, Beaty TH, Strathdee SA, Farzadegan H, Markham RB, et al. Genetic influence of CXCR6 chemokine receptor alleles on PCP-mediated AIDS progression among African Americans. Genes Immun 2003; 4:245-250. (Pubitemid 39562122)
29. Fabris A, Catamo E, Segat L, Morgutti M, Arraes LC, de Lima-Filho JL, et al. Association between HLA-G 3'UTR 14-bp polymorphism and HIV vertical transmission in Brazilian children. AIDS 2009; 23:177-182.
30. Fellay J, Ge D, Shianna KV, Colombo S, Ledergerber B, Cirulli ET, et al. Common genetic variation and the control of HIV-1 in humans. PLoS Genet 2009; 5:e1000791.
31. Fellay J, Shianna KV, Ge D, Colombo S, Ledergerber B, Weale M, et al. A whole-genome association study of major determinants for host control of HIV-1. Science 2007; 317:944-947. (Pubitemid 47301321)
32. Geczy AF, Kuipers H, Coolen M, Ashton LJ, Kennedy C, Ng G, et al. HLA and other host factors in transfusion-acquired HIV-1 infection. Hum Immunol 2000; 61:172-176. (Pubitemid 30075240)
33. Goldschmidt V, Bleiber G, May M, Martinez R, Ortiz M, Telenti A. Role of common human TRIM5alpha variants in HIV-1 disease progression. Retrovirology 2006; 3:54.
34. Gonzalez E, Dhanda R, Bamshad M, Mummidi S, Geevarghese R, Catano G, et al. Global survey of genetic variation in CCR5, RANTES, and MIP-1alpha: impact on the epidemiology of the HIV-1 pandemic. ProcNatl Acad SciUSA2001; 98:5199-5204.
35. Gonzalez E, Rovin BH, Sen L, Cooke G, Dhanda R, Mummidi S, et al. HIV-1 infection and AIDS dementia are influenced by a mutant MCP-1 allele linked to increased monocyte infiltration of tissues and MCP-1 levels. Proc Natl Acad Sci USA 2002; 99:13795-13800. (Pubitemid 35215460)
36. Gonzalez E, Kulkarni H, Bolivar H, Mangano A, Sanchez R, Catano G, et al. The influence of CCL3L1 gene-containing segmental duplications on HIV-1/AIDS susceptibility. Science 2005; 307:1434-1440. (Pubitemid 40321934)
37. Gonzalez S, Tirado G, Revuelta G, Yamamura Y, Lu Y, Nerurkar VR, et al. CCR5 chemokine receptor genotype frequencies among Puerto Rican HIV-1-seropositive individuals. Bol Asoc Med P R 1998; 90:12-15.
38. Haddad R, Ciliao Alves DC, Rocha-Junior MC, Azevedo R, do Socorro Pombo-de-Oliveira M, Takayanagui OM, et al. HLA-G 14-bp insertion/deletion polymorphism is a risk factor for HTLV-1 infection. AIDS Res Hum Retroviruses 2011; 27:283-288.
39. Harrison GA, Humphrey KE, Jakobsen IB, Cooper DW. A 14 bp deletion polymorphism in the HLA-G gene. Hum Mol Genet 1993; 2:2200. (Pubitemid 24003437)
40. Ji H, Ball TB, Kimani J, Plummer FA. Novel interferon regulatory factor-1 polymorphisms in a Kenyan population revealed by complete gene sequencing. J Hum Genet 2004; 49:528-535. (Pubitemid 39516981)
41. Ji H, Ball TB, Liang BB, Kimani J, Plummer FA. Human interferon regulatory factor-1 gene and its promoter sequences revealed by population-based complete gene sequencing. DNA Seq 2008; 19:326-331.
42. Liao HX, Montefiori DC, Patel DD, Lee DM, Scott WK, Pericak-Vance M, et al. Linkage of the CCR5 Delta 32 mutation with a functional polymorphism of CD45RA. J Immunol 2000; 165:148-157. (Pubitemid 30429502)
43. Libert F, Cochaux P, Beckman G, Samson M, Aksenova M, Cao A, et al. The deltaccr5 mutation conferring protection against HIV-1 in Caucasian populations has a single and recent origin in Northeastern Europe. Hum Mol Genet 1998; 7:399-406. (Pubitemid 28120628)
44. Lin A, Yan WH, Xu HH, Tang LJ, Chen XF, Zhu M, et al. 14 bp deletion polymorphism in the HLA-G gene is a risk factor for idiopathic dilated cardiomyopathy in a Chinese Han population. Tissue Antigens 2007; 70:427-431. (Pubitemid 47537405)
45. Martin MP, Carrington M, Dean M, O'Brien SJ, Sheppard HW, Wegner SA, et al. CXCR4 polymorphisms and HIV-1 pathogenesis. J Acquir Immune Defic Syndr HumRetrovirol 1998; 19:430.
46. Martin MP, Lederman MM, Hutcheson HB, Goedert JJ, Nelson GW, van Kooyk Y, et al. Association of DC-SIGN promoter polymorphism with increased risk for parenteral, but not mucosal, acquisition of human immunodeficiency virus type 1 infection. J Virol 2004; 78:14053-14056. (Pubitemid 39612803)
47. Matt C, Roger M. Genetic determinants of pediatric HIV-1 infection: vertical transmission and disease progression among children. Mol Med 2001; 7:583-589. (Pubitemid 34175286)
48. McDermott DH, Colla JS, Kleeberger CA, Plankey M, Rosenberg PS, Smith ED, et al. Genetic polymorphism in CX3CR1 and risk of HIV disease. Science 2000; 290:2031.
49. McDermott DH, Zimmerman PA, Guignard F, Kleeberger CA, Leitman SF, Murphy PM. CCR5 promoter polymorphism and HIV-1 disease progression. Multicenter AIDS Cohort Study (MACS). Lancet 1998; 352:866-870. (Pubitemid 28416720)
50. McDermott DH, Beecroft MJ, Kleeberger CA, Al-Sharif FM, Ollier WE, Zimmerman PA, et al. Chemokine RANTES promoter polymorphism affects risk of both HIV infection and disease progression in the Multicenter AIDS Cohort Study. AIDS 2000; 14:2671-2678. (Pubitemid 32118720)
51. Pelak K, Goldstein DB, Walley NM, Fellay J, Ge D, Shianna KV, et al. Host determinants of HIV-1 control in African Americans. J Infect Dis 2010; 201:1141-1149.
52. Petersen DC, Glashoff RH, Shrestha S, Bergeron J, Laten A, Gold B, et al. Risk for HIV-1 infection associated with a common CXCL12 (SDF1) polymorphism and CXCR4 variation in an African population. J Acquir Immune Defic Syndr 2005; 40:521-526. (Pubitemid 41669154)
53. Price H, Lacap P, Tuff J, Wachihi C, Kimani J, Ball TB, et al. A TRIM5alpha exon 2 polymorphism is associated with protection from HIV-1 infection in the Pumwani sex worker cohort. AIDS 2010; 24:1813-1821.
54. One copy of mutation may help resistance: study. AIDS Alert 2002; 17:23-24, 14.
55. An P, Martin MP, Nelson GW, Carrington M, Smith MW, Gong K, et al. Influence of CCR5 promoter haplotypes on AIDS progression in African-Americans. AIDS 2000; 14:2117-2122.
56. Arenzana-Seisdedos F, Virelizier JL, Rousset D, Clark-Lewis I, Loetscher P, Moser B, et al. HIV blocked by chemokine antagonist. Nature 1996; 383:400. (Pubitemid 26330820)
57. Blanpain C, Libert F, Vassart G, Parmentier M. CCR5 and HIV infection. Receptors Channels 2002; 8:19-31.
58. Chalmet K, Van Wanzeele F, Demecheleer E, Dauwe K, Pelgrom J, Van Der Gucht B, et al. Impact of Delta 32-CCR5 heterozygosity on HIV-1 genetic evolution and variability-a study of 4 individuals infected with closely related HIV-1 strains. Virology 2008; 379:213-222.
59. Bratt G, Sandstrom E, Albert J, Samson M, Wahren B. The influence of MT-2 tropism on the prognostic implications of the delta32 deletion in the CCR-5 gene. AIDS 1997; 11:1415-1419. (Pubitemid 27421172)
60. Diaz FJ, Vega JA, Patino PJ, Bedoya G, Nagles J, Villegas C, et al. Frequency of CCR5 delta-32 mutation in human immunodeficiency virus (HIV)-seropositive and HIV-exposed seronegative individuals and in general population of Medellin, Colombia. Mem Inst Oswaldo Cruz 2000; 95:237-242.
61. Gonzalez E, Bamshad M, Sato N, Mummidi S, Dhanda R, Catano G, et al. Race-specific HIV-1 disease-modifying effects associated with CCR5 haplotypes. Proc Natl Acad Sci USA 1999; 96:12004-12009. (Pubitemid 29502848)
62. Huang Y, Paxton WA, Wolinsky SM, Neumann AU, Zhang L, He T, et al. The role of a mutant CCR5 allele in HIV-1 transmission and disease progression. Nat Med 1996; 2: 1240-1243. (Pubitemid 26375409)
63. Hummel S, Schmidt D, Kremeyer B, Herrmann B, Oppermann M. Detection of the CCR5-Delta32 HIV resistance gene in Bronze Age skeletons. Genes Immun 2005; 6:371-374. (Pubitemid 40903412)
64. Kokkotou E, Philippon V, Gueye-Ndiaye A, Mboup S, Wang WK, Essex M, et al. Role of the CCR5 delta 32 allele in resistance to HIV-1 infection in west Africa. J Hum Virol 1998; 1:469-474. (Pubitemid 128543592)
65. Hedrick PW, Verrelli BC. "Ground truth" for selection on CCR5-Delta32. Trends Genet 2006; 22:293-296.
66. Speelmon EC, Livingston-Rosanoff D, Li SS, Vu Q, Bui J, Geraghty DE, et al. Genetic association of the antiviral restriction factor TRIM5alpha with human immunodeficiency virus type 1 infection. J Virol 2006; 80:2463-2471. (Pubitemid 43271552)
67. Diaz-Griffero F, Perron M, McGee-Estrada K, Hanna R, Maillard PV, Trono D, et al. A human TRIM5alpha B30. 2/SPRY domain mutant gains the ability to restrict and prematurely uncoat B-tropic murine leukemia virus. Virology 2008; 378:233-242.
68. Takeuchi H, Matano T. Host factors involved in resistance to retroviral infection. Microbiol Immunol 2008; 52:318-325.
69. Su RC, Sivro A, Kimani J, Jaoko W, Plummer FA, Ball TB. Epigenetic control of IRF1 responses in HIV-exposed seronegative versus HIV-susceptible individuals. Blood 2011; 117: 2649-2657.
70. Hardie RA, Knight E, Bruneau B, Semeniuk C, Gill K, Nagelkerke N, et al. A common human leucocyte antigen-DP genotype is associated with resistance to HIV-1 infection in Kenyan sex workers. AIDS 2008; 22:2038-2042.
71. Hardie RA, Luo M, Bruneau B, Knight E, Nagelkerke NJ, Kimani J, et al. Human leukocyte antigen-DQ alleles and haplotypes and their associations with resistance and susceptibility to HIV-1 infection. AIDS 2008; 22:807-816. (Pubitemid 351563829)
72. Lacap PA, Huntington JD, Luo M, Nagelkerke NJ, Bielawny T, Kimani J, et al. Associations of human leukocyte antigen DRB with resistance or susceptibility to HIV-1 infection in the Pumwani Sex Worker Cohort. AIDS 2008; 22:1029-1038. (Pubitemid 351769741)
73. MacDonald KS, Fowke KR, Kimani J, Dunand VA, Nagelkerke NJ, Ball TB, et al. Influence of HLA supertypes on susceptibility and resistance to human immunodeficiency virus type 1 infection. J Infect Dis 2000; 181:1581-1589. (Pubitemid 30387748)
74. Alimonti JB, Kimani J, Matu L, Wachihi C, Kaul R, Plummer FA, et al. Characterization of CD8 T-cell responses in HIV-1-exposed seronegative commercial sex workers from Nairobi, Kenya. Immunol Cell Biol 2006; 84:482-485. (Pubitemid 44286043)
75. Alimonti JB, Koesters SA, Kimani J, Matu L, Wachihi C, Plummer FA, et al. CD4R T cell responses in HIV-exposed seronegative women are qualitatively distinct from those in HIV-infected women. J Infect Dis 2005; 191:20-24. (Pubitemid 40041395)
76. Kaul R, Dong T, Plummer FA, Kimani J, Rostron T, Kiama P, et al. CD8(R) lymphocytes respond to different HIV epitopes in seronegative and infected subjects. J Clin Invest 2001; 107: 1303-1310. (Pubitemid 32494547)
77. Kaul R, Plummer FA, Kimani J, Dong T, Kiama P, Rostron T, et al. HIV-1-specific mucosal CD8R lymphocyte responses in the cervix of HIV-1-resistant prostitutes in Nairobi. J Immunol 2000; 164:1602-1611. (Pubitemid 30067280)
78. Kaul R, Rutherford J, Rowland-Jones SL, Kimani J, Onyango JI, Fowke K, et al. HIV-1 Env-specific cytotoxic T-lymphocyte responses in exposed, uninfected Kenyan sex workers: a prospective analysis. AIDS 2004; 18:2087-2089. (Pubitemid 39463364)
79. McLaren PJ, Ball TB, Wachihi C, Jaoko W, Kelvin DJ, Danesh A, et al. HIV-exposed seronegative commercial sex workers show a quiescent phenotype in the CD4R T cell compartment and reduced expression of HIV-dependent host factors. J Infect Dis 2010; 202 (Suppl 3):S339-S344.
80. Songok EM, Luo M, Liang B, McLaren P, Kaefer N, Apidi W, et al. Microarray analysis of HIV resistant female sex workers reveal a gene expression signature pattern reminiscent of a lowered immune activation state. PLoS One 2012; 7:e30048.
81. Geraghty DE, Koller BH, Orr HT. A human major histocompatibility complex class I gene that encodes a protein with a shortened cytoplasmic segment. Proc Natl Acad Sci USA 1987; 84:9145-9149.
82. Arnaiz-Villena A, Martinez-Laso J, Serrano-Vela JI, Reguera R, Moscoso J. HLA-G polymorphism and evolution. Tissue Antigens 2007; 69 (Suppl 1):156-159. (Pubitemid 46625877)
83. Ishitani A, Sageshima N, Lee N, Dorofeeva N, Hatake K, Marquardt H, et al. Protein expression and peptide binding suggest unique and interacting functional roles for HLA-E, F, and G in maternal-placental immune recognition. J Immunol 2003; 171:1376-1384. (Pubitemid 36900070)
84. Favier B, LeMaoult J, Rouas-Freiss N, Moreau P, Menier C, Carosella ED. Research on HLA-G: an update. Tissue Antigens 2007; 69:207-211. (Pubitemid 46696937)
85. Carosella ED. The tolerogenic molecule HLA-G. Immunol Lett 2011; 138:22-24.
86. Lajoie J, Massinga Loembe M, Poudrier J, Guedou F, Pepin J, Labbe AC, et al. Blood soluble human leukocyte antigen G levels are associated with human immunodeficiency virus type 1 infection in Beninese commercial sex workers. Hum Immunol 2010; 71:182-185.
87. Donaghy L, Gros F, Amiot L, Mary C, Maillard A, Guiguen C, et al. Elevated levels of soluble non-classical major histocompatibility class I molecule human leucocyte antigen (HLA)-G in the blood of HIV-infected patients with or without visceral leishmaniasis. Clin Exp Immunol 2007; 147:236-240. (Pubitemid 46096000)
88. Aikhionbare FO, Kumaresan K, Shamsa F, Bond VC. HLA-G DNA sequence variants and risk of perinatal HIV-1 transmission. AIDS Res Ther 2006; 3:28.
89. Matte C, Lajoie J, Lacaille J, Zijenah LS, Ward BJ, Roger M. Functionally active HLA-G polymorphisms are associated with the risk of heterosexual HIV-1 infection in African women. AIDS 2004; 18:427-431. (Pubitemid 38365869)
90. Segat L, Catamo E, Fabris A, Morgutti M, D'Agaro P, Campello C, et al. HLA-GM0105N allele is associated with augmented risk for HIV infection in white female patients. AIDS 2010; 24: 1961-1964.
91. Lajoie J, Hargrove J, Zijenah LS, Humphrey JH, Ward BJ, Roger M. Genetic variants in nonclassical major histocompatibility complex class I human leukocyte antigen (HLA)-E and HLA-G molecules are associated with susceptibility to heterosexual acquisition of HIV-1. J Infect Dis 2006; 193:298-301. (Pubitemid 43113493)
92. Luo M, Blanchard J, Pan Y, Brunham K, Brunham RC. Highresolution sequence typing of HLA-DQA1 and-DQB1 exon 2 DNA with taxonomy-based sequence analysis (TBSA) allele assignment. Tissue Antigens 1999; 54:69-82. (Pubitemid 29326932)
93. Luo M, Blanchard J, Brunham K, Pan Y, Shen CX, Lu H, et al. Two-step high resolution sequence-based HLA-DRB typing of exon 2 DNA with taxonomy-based sequence analysis allele assignment. Hum Immunol 2001; 62:1294-1310. (Pubitemid 33032283)
94. Hens N, Aerts M, Molenberghs G. Model selection for incomplete and design-based samples. Stat Med 2006; 25:2502-2520. (Pubitemid 44057052)
95. Luo M, Daniuk CA, Diallo TO, Capina RE, Kimani J, Wachihi C, et al. For protection from HIV-1 infection, more might not be better: a systematic analysis of HIV Gag epitopes of two alleles associated with different outcomes of HIV-1 infection. J Virol 2012; 86:1166-1180.
96. Park Y, Kim YS, Kwon OJ, Kim HS. Allele frequencies of human leukocyte antigen-G in a Korean population. Int J Immunogenet 2011; 39:39-45.
97. Donadi EA, Castelli EC, Arnaiz-Villena A, Roger M, Rey D, Moreau P. Implications of the polymorphism of HLA-G on its function, regulation, evolution and disease association. Cell Mol Life Sci 2011; 68:369-395.
98. Thibodeau V, Lajoie J, Labbe AC, Zannou MD, Fowke KR, Alary M, et al. High level of soluble HLA-G in the female genital tract of Beninese commercial sex workers is associated with HIV-1 infection. PLoS One 2011; 6:e25185.
99. Rebmann V, van der Ven K, Passler M, Pfeiffer K, Krebs D, Grosse-Wilde H. Association of soluble HLA-G plasma levels with HLA-G alleles. Tissue Antigens 2001; 57:15-21. (Pubitemid 32151071)