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Volumn 11, Issue 10, 1997, Pages

Homozygous Δ32 deletion of the CCR-5 chemokine receptor gene in an HIV-1-infected patient

Author keywords

32 32 deletion; CCR 5 gene; HIV 1 non syncytium inducing macrophage tropic isolates; HIV 1 syncytium inducing T cell tropic isolates

Indexed keywords

CD4 ANTIGEN; CHEMOKINE RECEPTOR; DNA;

EID: 8544234244     PISSN: 02699370     EISSN: None     Source Type: Journal    
DOI: 10.1097/00002030-199710000-00001     Document Type: Article
Times cited : (115)

References (20)
  • 1
    • 0030002637 scopus 로고    scopus 로고
    • HIV-1 entry cofactor: Functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor
    • Feng Y, Broder CC, Kennedy PE, Berger EA: HIV-1 entry cofactor: functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor. Science 1996, 272:872-877.
    • (1996) Science , vol.272 , pp. 872-877
    • Feng, Y.1    Broder, C.C.2    Kennedy, P.E.3    Berger, E.A.4
  • 2
    • 16044370087 scopus 로고    scopus 로고
    • The CXC chemokine SDF-1 is the ligand for LESTR/fusin and prevents infection by T-cell-line-adapted HIV-1
    • Oberlin E, Amara A, Bachelerie F, et al.: The CXC chemokine SDF-1 is the ligand for LESTR/fusin and prevents infection by T-cell-line-adapted HIV-1. Nature 1996, 382:833-835.
    • (1996) Nature , vol.382 , pp. 833-835
    • Oberlin, E.1    Amara, A.2    Bachelerie, F.3
  • 3
    • 0029775576 scopus 로고    scopus 로고
    • The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry
    • Bleul CC, Parolin C, Clark-Lewis I, et al.: The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry. Nature 1996, 382:829-832.
    • (1996) Nature , vol.382 , pp. 829-832
    • Bleul, C.C.1    Parolin, C.2    Clark-Lewis, I.3
  • 4
    • 15844389650 scopus 로고    scopus 로고
    • HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5
    • Dragic T, Litvin V, Allaway GP, et al.: HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5. Nature 1996, 381:667-673.
    • (1996) Nature , vol.381 , pp. 667-673
    • Dragic, T.1    Litvin, V.2    Allaway, G.P.3
  • 5
    • 15844419153 scopus 로고    scopus 로고
    • Identification of a major coreceptor for primary isolates of HIV-1
    • Deng H, Liu R, Ellmeier W, et al.: Identification of a major coreceptor for primary isolates of HIV-1. Nature 1996, 381:661-667.
    • (1996) Nature , vol.381 , pp. 661-667
    • Deng, H.1    Liu, R.2    Ellmeier, W.3
  • 6
    • 0030018156 scopus 로고    scopus 로고
    • CC CKR5: A RANTES, MIP-1α, MIP-1β receptor as a fusion cofactor for macrophage-tropic HIV-1
    • Alkhatib G, Combadiere C, Broder CC, et al.: CC CKR5: a RANTES, MIP-1α, MIP-1β receptor as a fusion cofactor for macrophage-tropic HIV-1. Science 1996, 272:1955-1958.
    • (1996) Science , vol.272 , pp. 1955-1958
    • Alkhatib, G.1    Combadiere, C.2    Broder, C.C.3
  • 7
    • 0030604727 scopus 로고    scopus 로고
    • A dual-tropic primary HIV-1 isolate that uses fusin and the beta-chemokine receptors CKR-5, CKR-3, and CKR-2b as fusion cofactors
    • Doranz BJ, Rucker J, Yi Y, et al.: A dual-tropic primary HIV-1 isolate that uses fusin and the beta-chemokine receptors CKR-5, CKR-3, and CKR-2b as fusion cofactors. Cell 1996, 85:1149-1158.
    • (1996) Cell , vol.85 , pp. 1149-1158
    • Doranz, B.J.1    Rucker, J.2    Yi, Y.3
  • 8
    • 16044373004 scopus 로고    scopus 로고
    • Resistance to HIV-1 infection in Caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene
    • Samson M, Libert F, Dorantz BJ, et al.: Resistance to HIV-1 infection in Caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene. Nature 1996, 382:722-725.
    • (1996) Nature , vol.382 , pp. 722-725
    • Samson, M.1    Libert, F.2    Dorantz, B.J.3
  • 9
    • 15844388931 scopus 로고    scopus 로고
    • Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection
    • Liu R, Paxton WA, Choe S, et al.: Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection. Cell 1996, 86:367-377.
    • (1996) Cell , vol.86 , pp. 367-377
    • Liu, R.1    Paxton, W.A.2    Choe, S.3
  • 10
    • 16044367526 scopus 로고    scopus 로고
    • The role of a mutant CCR5 allele in HIV-1 transmission and disease progression
    • Huang Y, Paxton WA, Wolinsky SM, et al.: The role of a mutant CCR5 allele in HIV-1 transmission and disease progression. Nature Med 1996, 2:1240-1243.
    • (1996) Nature Med , vol.2 , pp. 1240-1243
    • Huang, Y.1    Paxton, W.A.2    Wolinsky, S.M.3
  • 11
    • 0001633495 scopus 로고    scopus 로고
    • Genetic restriction of HIV-1 infection and progression to AIDS by a detection allele of the CKR5 structural gene
    • Dean M, Carrington M, Winkler C, et al.: Genetic restriction of HIV-1 infection and progression to AIDS by a detection allele of the CKR5 structural gene. Science 1996, 273:1856-1862.
    • (1996) Science , vol.273 , pp. 1856-1862
    • Dean, M.1    Carrington, M.2    Winkler, C.3
  • 12
    • 0027422278 scopus 로고
    • Genotypic and phenotypic characterization of HIV-1 in patients with primary infection
    • Zhu T, Mo H, Wang N, et al.: Genotypic and phenotypic characterization of HIV-1 in patients with primary infection. Science 1993, 261:1179-1181.
    • (1993) Science , vol.261 , pp. 1179-1181
    • Zhu, T.1    Mo, H.2    Wang, N.3
  • 13
    • 0027537480 scopus 로고
    • Prognostic value of human immunodeficiency virus type 1 biological phenotype for rate of CD4 depletion and progression to AIDS
    • Koot M, Keet IPM, Vos AVH, et al.: Prognostic value of human immunodeficiency virus type 1 biological phenotype for rate of CD4 depletion and progression to AIDS. Ann Intern Med 1993, 118:681-688.
    • (1993) Ann Intern Med , vol.118 , pp. 681-688
    • Koot, M.1    Keet, I.P.M.2    Vos, A.V.H.3
  • 14
    • 0026600926 scopus 로고
    • Biological phenotype of human immunodeficiency virus type 1 clones at different stages of infection: Progression of disease is associated with a shift from monocyte-tropic to T-cell tropic virus population
    • Schuitemaker H, Koot M, Kootstra NA, et al.: Biological phenotype of human immunodeficiency virus type 1 clones at different stages of infection: progression of disease is associated with a shift from monocyte-tropic to T-cell tropic virus population. J Virol 1992, 66:1354-1360.
    • (1992) J Virol , vol.66 , pp. 1354-1360
    • Schuitemaker, H.1    Koot, M.2    Kootstra, N.A.3
  • 15
    • 0029081229 scopus 로고
    • Lower prevalence and incidence of HIV-1 syncytium-inducing phenotype among injecting drug users compared with homosexual men
    • Spijkerman IJB, Koot M, Prins M, et al.: Lower prevalence and incidence of HIV-1 syncytium-inducing phenotype among injecting drug users compared with homosexual men. AIDS 1995, 9:1085-1092.
    • (1995) AIDS , vol.9 , pp. 1085-1092
    • Spijkerman, I.J.B.1    Koot, M.2    Prins, M.3
  • 16
    • 0028091755 scopus 로고
    • Macrophage-tropic variants initiate human immunodeficiency virus type 1 infection after sexual, parenteral, and vertical transmission
    • van't Wout AB, Kootstra NA, Mulder-Kampinga GA, et al.: Macrophage-tropic variants initiate human immunodeficiency virus type 1 infection after sexual, parenteral, and vertical transmission. J Clin Invest 1994, 94:2060-2067.
    • (1994) J Clin Invest , vol.94 , pp. 2060-2067
    • Van't Wout, A.B.1    Kootstra, N.A.2    Mulder-Kampinga, G.A.3
  • 17
    • 0029816985 scopus 로고    scopus 로고
    • HIV-1 phenotype correlates with the stage of infection in vertically infected children
    • Balotta C, Viganò A, Riva C, et al.: HIV-1 phenotype correlates with the stage of infection in vertically infected children. AIDS Res Hum Retroviruses 1996, 12:1247-1253.
    • (1996) AIDS Res Hum Retroviruses , vol.12 , pp. 1247-1253
    • Balotta, C.1    Viganò, A.2    Riva, C.3
  • 18
    • 0028203596 scopus 로고
    • Dynamics of molecular parameters of human immunodeficiency virus type 1 activity in vivo
    • Bagnarelli P, Valenza A, Menzo S, et al.: Dynamics of molecular parameters of human immunodeficiency virus type 1 activity in vivo. J Virol 1994, 68:2495-2502.
    • (1994) J Virol , vol.68 , pp. 2495-2502
    • Bagnarelli, P.1    Valenza, A.2    Menzo, S.3
  • 19
    • 0031025113 scopus 로고    scopus 로고
    • Macrophage tropism of human immunodeficiency virus type 1 and utilization of the CC-CKR5 coreceptor
    • Cheng-Mayer C, Liu R, Landau NR, Stamatatos L: Macrophage tropism of human immunodeficiency virus type 1 and utilization of the CC-CKR5 coreceptor. J Virol 1997, 71:1657-1661.
    • (1997) J Virol , vol.71 , pp. 1657-1661
    • Cheng-Mayer, C.1    Liu, R.2    Landau, N.R.3    Stamatatos, L.4
  • 20
    • 0031051739 scopus 로고    scopus 로고
    • HIV-1 infection in an individual homozygous for the CCR5 deletion allele
    • Biti R, French R, Young J, Bennetts B, Stewart G: HIV-1 infection in an individual homozygous for the CCR5 deletion allele. Nature Med 1997, 3:252-253.
    • (1997) Nature Med , vol.3 , pp. 252-253
    • Biti, R.1    French, R.2    Young, J.3    Bennetts, B.4    Stewart, G.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.