Resistance to HIV-1 infection among persistently seronegative prostitutes in Nairobi, Kenya

Lancet

Volumn 348, Issue 9038, 1996, Pages 1347-1351

  Fowke, Keith R ^a   Nagelkerke, Nico J D ^a,b   Kimani, Joshua ^b   Simonsen, J Neil ^a   Anzala, Aggrey O ^a,b   Bwayo, Job J ^b   MacDonald, Kelly S ^a,b   Ngugi, Elizabeth N ^b   Plummer, Francis A ^a,b  

^a UNIVERSITY OF MANITOBA   (Canada)

^b UNIVERSITY OF NAIROBI   (Kenya)

Author keywords

[No Author keywords available]

Indexed keywords

NEF PROTEIN; VIF PROTEIN;

ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; DATA ANALYSIS; ENVELOPE GENE; FEMALE; FOLLOW UP; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNITY; INCIDENCE; INFECTION RESISTANCE; KENYA; MAJOR CLINICAL STUDY; PERSISTENT INFECTION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROSTITUTION; RISK FACTOR; SEROCONVERSION; SEXUAL BEHAVIOR; SEXUALLY TRANSMITTED DISEASE; SURVIVAL;

EID: 0030590749     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(95)12269-2     Document Type: Article

References (31)

1. Borkowsky W, Krasinski K, Moore T, Papeavangelou V. Lymphocyte proliferative responses to HIV-1 envelope and core antigens by infected and uninfected adults and children. AIDS Res Hum Retroviruses. 6:1990;673-678.
2. Ranki A, Mattinen S, Yarchoan R, et al. T-cell response towards HIV in infected individuals with and without zidovudine therapy, and in HIV-exposed sexual partners. AIDS. 3:1989;63-69.
3. Clerici M, Giorgi JV, Chou C-C, et al. Cell-mediated immune response to human immunodeficiency virus (HIV) type 1 in seronegative homosexual men with recent sexual exposure to HIV-1. J Infect Dis. 165:1992;1012-1019.
4. Barcellini W, Rizzardi GP, Velati C, et al. In vitro production of type 1 and type 2 cytokines by peripheral blood mononuclear cells from high-risk HIV-negative intravenous drug users. AIDS. 9:1995;691-694.
5. H2 switch is a critical step in the etiology of HIV infection. Immunol Today. 14:1993;107-111.
6. Salk J, Bretscher PA, Salk PL, Clerici M, Shearer GM. A strategy for prophylactic vaccination against HIV. Science. 260:1993;1270-1272.
7. Cheynier R, Langlade-Demoyen P, Marescot M-R, et al. Cytotoxic T lymphocyte responses in the peripheral blood of children born to human immunodeficiency virus-1-infected mothers. Eur J Immunol. 22:1992;2211-2217.
8. Rowland-Jones SL, Nixon DF, Aldhous MC, et al. HIV-specific cytotoxic T-cell activity in an HIV-exposed but uninfected infants. Lancet. 341:1993;860-861.
9. Langlade-Demoyen P, Ngo-Giang-Huong N, Ferchal F, Oksenhendler E. Human immunodeficiency virus (HIV) nef-specific cytotoxic T lymphocytes in noninfected heterosexual contact of HIV-infected patients. J Clin Invest. 93:1994;1293-1297.
10. Rowland-Jones S, Sutton J, Ariyoshi K, et al. HIV-specific cytotoxic T-cells in HIV-exposed but uninfected Gambian women. Nat Med. 1:1995;59-64.
11. Levy JA. HIV pathogenesis and long-term survival. AIDS. 7:1993;1401-1410.
12. Travers K, Mboup S, Marlink R, et al. Natural protection against HIV-1 infection provided by HIV-2. Science. 268:1995;1612-1616.
13. Simonsen JN, Plummer FA, Ngugi EN, et al. HIV infection among lower socioeconomic strata prostitutes in Nairobi. AIDS. 4:1990;139-144.
14. Fischl MA, Dickinson GM, Flanagan S, Fletcher MA. Human immunodeficiency virus (HIV) among female prostitutes in south Florida. II International Conference on AIDS Washington DC, June 3-5, 1987 (abstr W2·2).
15. Plummer FA, Simonsen JN, Cameron DW, et al. Cofactors in male-female sexual transmission of human immunodeficiency virus type 1. J Infect Dis. 163:1991;233-239.
16. Dawood MR, Allan R, Fowke K, Embree J, Hammond GW. Development of oligonucleotide primers and probes against structural and regulatory genes of human immunodeficiency virus type 1 (HIV-1) and their use for amplification of HIV-1 provirus by using polymerase chain reaction. J Clin Microbiol. 30:1992;2279-2283.
17. Ou C-Y, Kwok S, Mitchell SW, et al. DNA amplification for direct detection og HIV-1 in DNA of peripheral blood mononuclear cells. Science. 239:1988;295-297.
18. Fowke K, Mohammed Z, Plummer FA. detection of HIV-1 sequences in lymphocyte DNA from African specimens of the polymerase chain reaction (PCR). Presented at the Fifth International Conference on AIDS in Africa, Kinshasa, Zaire, Oct 10-12, 1990 (abstr FPC 29).
19. Elandt-Johnson RC, Johnson NL. Survival models and data analysis. New York: John Wiley, 1980.
20. Ngugi EN, Plummer FA, Simonsen JN, et al. Prevention of HIV transmission in Africa: effectiveness of condom promotion and health education among high-risk prostitutes. Lancet. 2:1988;887-890.
21. Simonsen JN, Cameron DW, Gakinya MN, et al. Human immunodeficiency virus infection among men with sexually transmitted diseases: experience from a centre in Africa. N Engl J Med. 319:1988;274-287.
22. Laga M, Manoka A, Kivuvu M, et al. Non-ulcerative sexually transmitted diseases as risk factors for HIV-1 transmission in women: results from a cohort study. AIDS. 7:1993;95-102.
23. Imagawa DT, Lee MH, Wolinsky SM, et al. Human immunodeficiency virus type 1 infection in homosexual men who remain seronegative for prolonged periods. N Engl J Med. 320:1989;1458-1462.
24. Willerford DM, Bwayo JJ, Hensel M, et al. Human immunodeficiency virus infection among high-risk seronegative prostitutes in Nairobi. J Infect Dis. 167:1993;1414-1417.
25. Pan L-Z, Sheppard HW, Winkelstein W, Levy JA. Lack of detection of human immunodeficiency virus in persistently seronegative homosexual men with high or medium risks for infection. J Infect Dis. 164:1991;962-964.
26. Bruisten SM, Koppelman MHGM, Dekker JT, et al. Concordance of human immunodeficiency virus detection by polymerase chain reaction and by serologic assays in Dutch cohort of seronegative homosexual men. J Infect Dis. 166:1992;620-622.
27. Pantaleo G, Graziosi C, Demaraest JF, et al. HIV infection is active and progressive in lymphoid tissue during the clinically latent stage of disease. Nature. 362:1993;355-358.
28. Anzala OA, Nagelkerke NJD, Bwayo JJ, et al. Rapid progression to disease in African sex workers with human immunodeficiency virus type 1 infection. J Infect Dis. 171:1995;686-689.
29. Fowke KR, Rutherford J, Ball B, et al. Cellular immune responses correlate with protection against HIV-1 among women resistant to infection [5th Annual Canadian conference on HIV/AIDS Research]. Can J Infect Dis 1995; 6: 8B (abstr 138).
30. Paxton WA, Martin SR, Tse D, et al. Relative resistance to HIV-1 infection in CD4 lymphocytes from persons who remain uninfected despite multiple high-risk sexual exposures. Nat Med. 3:1996;412-417.
31. Dean M, Carrington M, Winkler C, et al. Genetic restriction of HIV-1 infection and progression to AIDS by a deletion allele of CKR5 structural gene. Science. 273:1996;1856-1862.