Selective proteasomal degradation of the B′β subunit of protein phosphatase 2A by the E3 ubiquitin ligase adaptor Kelch-like 15

Journal of Biological Chemistry

Volumn 287, Issue 52, 2012, Pages 43378-43389

  Oberg, Elizabeth A ^a   Nifoussi, Shanna K ^a,c   Gingrass, Anne Claude ^b   Strack, Stefan ^a  

^a UNIVERSITY OF IOWA   (United States)

^b MOUNT SINAI HOSPITAL   (Canada)

^c DARTMOUTH MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLULAR SUBSTRATES; DEPHOSPHORYLATIONS; E3 LIGASE; E3 UBIQUITIN LIGASES; HETEROTRIMERS; HOMODIMERIZATION; INTERACTORS; INTRACELLULAR SIGNALING; PROTEASOMAL DEGRADATION; PROTEIN KINASE; PROTEIN PHOSPHATASE 2A; REGULATORY SUBUNITS; SUBCELLULAR LOCATION; TISSUE EXPRESSION; TYROSINE HYDROXYLASE; UBIQUITIN LIGASES; UBIQUITYLATION;

AMINO ACIDS; ENZYMES; TISSUE;

PROTEINS;

ADAPTOR PROTEIN; CUL3 PROTEIN; HETEROTRIMER; HOLOENZYME; KELCH LIKE 15 PROTEIN; KLHL15 PROTEIN; PHOSPHOPROTEIN PHOSPHATASE 2A; PROTEASOME; REGULATOR PROTEIN; TYROSINE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; BETA CHAIN; BRAIN; CHEMICAL COMPOSITION; CONTROLLED STUDY; CUL3 GENE; DEPHOSPHORYLATION; DIMERIZATION; EMBRYO; GENE; HOMODIMERIZATION; HUMAN; HUMAN CELL; KLHL15 GENE; PPP2R5B GENE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; UBIQUITINATION;

CULLIN PROTEINS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HEK293 CELLS; HOLOENZYMES; HUMANS; MICROFILAMENT PROTEINS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN MULTIMERIZATION; PROTEIN PHOSPHATASE 2; PROTEOLYSIS;

EID: 84871593007     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.420281     Document Type: Article

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