BTB protein KLHL12 targets the dopamine D4 receptor for ubiquitination by a Cul3-based E3 ligase

Journal of Biological Chemistry

Volumn 283, Issue 17, 2008, Pages 11083-11096

  Rondou, Pieter ^a   Haegeman, Guy ^a   Vanhoenacker, Peter ^a,b   Van Craenenbroeck, Kathleen ^a  

^a GHENT UNIVERSITY   (Belgium)

^b ActoGeniX NV   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYMES; POLYMORPHISM;

ATTENTION DEFICIT HYPERACTIVITY DISORDERS; COUPLED RECEPTORS; DOPAMINE RECEPTORS; E3 LIGASE; EUKARYOTIC CELLS; KELCH DOMAINS; OVEREXPRESSION; SUBSTRATE SPECIFICITIES; THIRD INTRACELLULAR LOOPS; UBIQUITIN LIGASE; UBIQUITINATION; UBIQUITINATION ASSAYS;

BRAIN;

BINDING PROTEIN; CULLIN; DOPAMINE 4 RECEPTOR; PROTEIN KLHL12; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; ACTIN BINDING PROTEIN; CUL3 PROTEIN, HUMAN; DOPAMINE RECEPTOR; KLHL12 PROTEIN, HUMAN; KLHL12 PROTEIN, MOUSE; SIGNAL TRANSDUCING ADAPTOR PROTEIN; UBIQUITIN PROTEIN LIGASE;

ANIMAL TISSUE; ARTICLE; BINDING SITE; BRAIN; COMPLEX FORMATION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN POLYMORPHISM; PROTEIN PROTEIN INTERACTION; UBIQUITINATION; ANIMAL; BIOLOGICAL MODEL; ENZYME SPECIFICITY; GENE EXPRESSION REGULATION; GENETIC POLYMORPHISM; METABOLISM; PROTEIN BINDING; TWO HYBRID SYSTEM;

EUKARYOTA;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CULLIN PROTEINS; GENE EXPRESSION REGULATION; HUMANS; MICE; MICROFILAMENT PROTEINS; MODELS, BIOLOGICAL; POLYMORPHISM, GENETIC; PROTEIN BINDING; RECEPTORS, DOPAMINE; RECEPTORS, DOPAMINE D4; SUBSTRATE SPECIFICITY; TWO-HYBRID SYSTEM TECHNIQUES; UBIQUITIN-PROTEIN LIGASES;

EID: 45549091466     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M708473200     Document Type: Article

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