Combination lopinavir and ritonavir alter exogenous and endogenous bile acid disposition in sandwich-cultured rat hepatocytes

Drug Metabolism and Disposition

Volumn 41, Issue 1, 2013, Pages 188-196

  Griffin, LaToya M ^a   Watkins, Paul B ^a,b   Perry, Cassandra H ^c   St Claire III, Robert L ^c   Brouwer, Kim L R ^a  

^a UNC Hamner Institute for Drug Safety Sciences   (United States)

^b Hamner University of North Carolina   (United States)

^c Qualyst Transporter Solutions   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; ALPHA TAUROMURICHOLIC ACID; BETA TAUROMURICHOLIC ACID; BILE ACID; CHENODEOXYCHOLIC ACID; GLYCOCHENODEOXYCHOLIC ACID; GLYCOCHOLIC ACID; LACTATE DEHYDROGENASE; LOPINAVIR; RITONAVIR; TAUROCHENODEOXYCHOLIC ACID; TAUROCHOLIC ACID; UNCLASSIFIED DRUG;

ADAPTIVE IMMUNITY; ANIMAL CELL; ARTICLE; BILE ACID METABOLISM; BILIARY EXCRETION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; DRUG UPTAKE; ENZYME ASSAY; ENZYME IMMUNOASSAY; LIPID TRANSPORT; LIVER CELL; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; STEROL ANALYSIS;

ANIMALS; BILE ACIDS AND SALTS; CARBON RADIOISOTOPES; CELL SURVIVAL; CELLS, CULTURED; HEPATOCYTES; HIV PROTEASE INHIBITORS; LOPINAVIR; RATS; RITONAVIR;

RATTUS;

EID: 84871588005     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.112.047225     Document Type: Article

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