Differential disposition of chenodeoxycholic acid versus taurocholic acid in response to acute troglitazone exposure in rat hepatocytes

Toxicological Sciences

Volumn 120, Issue 2, 2011, Pages 371-380

  Marion, Tracy L ^a   Perry, Cassandra H ^b   St Claire III , Robert L ^b   Yue, Wei ^c   Brouwer, Kim L R ^a,c  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b Qualyst Inc   (United States)

^c University of North Carolina   (United States)

Author keywords

Bile acids; Hepatotoxicity; Sandwich cultured hepatocytes; Transport; Troglitazone

Indexed keywords

CARRIER PROTEIN; CHENODEOXYCHOLIC ACID; GLYCINE; MULTIDRUG RESISTANCE PROTEIN 2; TAURINE; TAUROCHOLIC ACID; TROGLITAZONE; XENOBIOTIC AGENT;

ANIMAL CELL; ARTICLE; BILE ACID METABOLISM; CELL CULTURE; CONTROLLED STUDY; DRUG EFFECT; DRUG EXPOSURE; DRUG RESPONSE; LIVER CELL; LIVER TOXICITY; MALE; NONHUMAN; RAT;

RATTUS;

EID: 79953071183     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfr014     Document Type: Article

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