Bile salt export pump inhibitors are associated with bile acid-dependent drug-induced toxicity in sandwich-cultured hepatocytes

Biochemical and Biophysical Research Communications

Volumn 416, Issue 3-4, 2011, Pages 313-317

  Ogimura, Eiichiro ^a   Sekine, Shuichi ^a   Horie, Toshiharu ^a  

^a CHIBA UNIVERSITY   (Japan)

Author keywords

Bile acid; Bile salt export pump; Drug induced liver injury; Sandwich cultured hepatocyte

Indexed keywords

1 AMINOBENZOTRIAZOLE; ALLOPURINOL; BILE SALT; CARBAMAZEPINE; CIMETIDINE; COLCHICINE; CYCLOSPORIN A; CYTOCHROME P450; DEOXYCHOLIC ACID; DICLOFENAC; ERYTHROMYCIN; ETHINYLESTRADIOL; FAMOTIDINE; FLUTAMIDE; GLIBENCLAMIDE; GLYCOCHENODEOXYCHOLIC ACID; IMIPRAMINE; INDOMETACIN; KETOCONAZOLE; QUINIDINE; RIFAMPICIN; RITONAVIR; SIMVASTATIN; TICLOPIDINE; TOLBUTAMIDE; TROGLITAZONE; UNINDEXED DRUG; VALPROIC ACID; VERAPAMIL; WARFARIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG METABOLISM; ENZYME ACTIVITY; LIVER CELL; LIVER CELL CULTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT; SANDWICH CULTURED HEPATOCYTE;

ANIMALS; BILE ACIDS AND SALTS; CELL CULTURE TECHNIQUES; CELLS, CULTURED; CYTOCHROME P-450 ENZYME SYSTEM; DRUG-INDUCED LIVER INJURY; HEPATOCYTES; HUMANS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84855906727     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2011.11.032     Document Type: Article

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