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Volumn 13, Issue 1, 2013, Pages 49-60

Breast cancer stem cell enrichment and isolation by mammosphere culture and its potential diagnostic applications

Author keywords

breast cancer; cancer stem cell; mammosphere; metastasis; microsystem

Indexed keywords

DIMETICONE; DOXORUBICIN; MACROGOL; PACLITAXEL; PACLITAXEL DERIVATIVE; POLYCARBONATE; SALINOMYCIN; SBT 1214; TRANILAST; UNCLASSIFIED DRUG;

EID: 84871578405     PISSN: 14737159     EISSN: 17448352     Source Type: Journal    
DOI: 10.1586/erm.12.117     Document Type: Review
Times cited : (29)

References (112)
  • 1
    • 0035499267 scopus 로고    scopus 로고
    • Stem cells, cancer, and cancer stem cells
    • Reya T, Morrison SJ, Clarke MF, Weissman IL. Stem cells, cancer, and cancer stem cells. Nature 414(6859), 105-111 (2001).
    • (2001) Nature , vol.414 , Issue.6859 , pp. 105-111
    • Reya, T.1    Morrison, S.J.2    Clarke, M.F.3    Weissman, I.L.4
  • 2
    • 0345059767 scopus 로고    scopus 로고
    • Applying the principles of stem-cell biology to cancer
    • Pardal R, Clarke MF, Morrison SJ. Applying the principles of stem-cell biology to cancer. Nat. Rev. Cancer 3(12), 895-902 (2003).
    • (2003) Nat. Rev. Cancer , vol.3 , Issue.12 , pp. 895-902
    • Pardal, R.1    Clarke, M.F.2    Morrison, S.J.3
  • 3
    • 0242667837 scopus 로고    scopus 로고
    • Stem cells and breast cancer: A field in transit
    • Smalley M, Ashworth A. Stem cells and breast cancer: a field in transit. Nat. Rev. Cancer 3(11), 832-844 (2003).
    • (2003) Nat. Rev. Cancer , vol.3 , Issue.11 , pp. 832-844
    • Smalley, M.1    Ashworth, A.2
  • 4
    • 34648821257 scopus 로고    scopus 로고
    • Molecular heterogeneity of breast carcinomas and the cancer stem cell hypothesis
    • Stingl J, Caldas C. Molecular heterogeneity of breast carcinomas and the cancer stem cell hypothesis. Nat. Rev. Cancer 7(10), 791-799 (2007).
    • (2007) Nat. Rev. Cancer , vol.7 , Issue.10 , pp. 791-799
    • Stingl, J.1    Caldas, C.2
  • 5
    • 69449096005 scopus 로고    scopus 로고
    • Heterogeneity in cancer: Cancer stem cells versus clonal evolution
    • Shackleton M, Quintana E, Fearon ER, Morrison SJ. Heterogeneity in cancer: cancer stem cells versus clonal evolution. Cell 138(5), 822-829 (2009).
    • (2009) Cell , vol.138 , Issue.5 , pp. 822-829
    • Shackleton, M.1    Quintana, E.2    Fearon, E.R.3    Morrison, S.J.4
  • 6
    • 0028091194 scopus 로고
    • A cell initiating human acute myeloid leukaemia after transplantation into SCID mice
    • Lapidot T, Sirard C, Vormoor J et al. A cell initiating human acute myeloid leukaemia after transplantation into SCID mice. Nature 367(6464), 645-648 (1994).
    • (1994) Nature , vol.367 , Issue.6464 , pp. 645-648
    • Lapidot, T.1    Sirard, C.2    Vormoor, J.3
  • 8
    • 21344454219 scopus 로고    scopus 로고
    • Isolation and in vitro propagation of tumorigenic breast cancer cells with stem/progenitor cell properties
    • Ponti D, Costa A, Zaffaroni N et al. Isolation and in vitro propagation of tumorigenic breast cancer cells with stem/progenitor cell properties. Cancer Res. 65(13), 5506-5511 (2005).
    • (2005) Cancer Res , vol.65 , Issue.13 , pp. 5506-5511
    • Ponti, D.1    Costa, A.2    Zaffaroni, N.3
  • 9
    • 0344735881 scopus 로고    scopus 로고
    • Cancerous stem cells can arise from pediatric brain tumors
    • Hemmati HD, Nakano I, Lazareff JA et al. Cancerous stem cells can arise from pediatric brain tumors. Proc. Natl Acad. Sci. USA 100(25), 15178-15183 (2003).
    • (2003) Proc. Natl Acad. Sci. USA , vol.100 , Issue.25 , pp. 15178-15183
    • Hemmati, H.D.1    Nakano, I.2    Lazareff, J.A.3
  • 10
    • 0141842674 scopus 로고    scopus 로고
    • Identification of a cancer stem cell in human brain tumors
    • Singh SK, Clarke ID, Terasaki M et al. Identification of a cancer stem cell in human brain tumors. Cancer Res. 63(18), 5821-5828 (2003).
    • (2003) Cancer Res , vol.63 , Issue.18 , pp. 5821-5828
    • Singh, S.K.1    Clarke, I.D.2    Terasaki, M.3
  • 11
    • 27144557960 scopus 로고    scopus 로고
    • A tumorigenic subpopulation with stem cell properties in melanomas
    • Fang D, Nguyen TK, Leishear K et al. A tumorigenic subpopulation with stem cell properties in melanomas. Cancer Res. 65(20), 9328-9337 (2005).
    • (2005) Cancer Res , vol.65 , Issue.20 , pp. 9328-9337
    • Fang, D.1    Nguyen, T.K.2    Leishear, K.3
  • 12
    • 33847052127 scopus 로고    scopus 로고
    • Identification of pancreatic cancer stem cells
    • Li C, Heidt DG, Dalerba P et al. Identification of pancreatic cancer stem cells. Cancer Res. 67(3), 1030-1037 (2007).
    • (2007) Cancer Res , vol.67 , Issue.3 , pp. 1030-1037
    • Li, C.1    Heidt, D.G.2    Dalerba, P.3
  • 13
    • 1642474273 scopus 로고    scopus 로고
    • Persistence of a small subpopulation of cancer stem-like cells in the C6 glioma cell line
    • Kondo T, Setoguchi T, Taga T. Persistence of a small subpopulation of cancer stem-like cells in the C6 glioma cell line. Proc. Natl Acad. Sci. USA 101(3), 781-786 (2004).
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , Issue.3 , pp. 781-786
    • Kondo, T.1    Setoguchi, T.2    Taga, T.3
  • 14
    • 44749086557 scopus 로고    scopus 로고
    • Growth of cancer cell lines under stem cell-like conditions has the potential to unveil therapeutic targets
    • Rappa G, Mercapide J, Anzanello F et al. Growth of cancer cell lines under stem cell-like conditions has the potential to unveil therapeutic targets. Exp. Cell Res. 314(10), 2110-2122 (2008).
    • (2008) Exp. Cell Res , vol.314 , Issue.10 , pp. 2110-2122
    • Rappa, G.1    Mercapide, J.2    Anzanello, F.3
  • 15
    • 16844368698 scopus 로고    scopus 로고
    • Tumour stem cells and drug resistance
    • Dean M, Fojo T, Bates S. Tumour stem cells and drug resistance. Nat. Rev. Cancer 5(4), 275-284 (2005).
    • (2005) Nat. Rev. Cancer , vol.5 , Issue.4 , pp. 275-284
    • Dean, M.1    Fojo, T.2    Bates, S.3
  • 16
    • 0034917716 scopus 로고    scopus 로고
    • The human ATP-binding cassette (ABC) transporter superfamily
    • Dean M, Rzhetsky A, Allikmets R. The human ATP-binding cassette (ABC) transporter superfamily. Genome Res. 11(7), 1156-1166 (2001).
    • (2001) Genome Res , vol.11 , Issue.7 , pp. 1156-1166
    • Dean, M.1    Rzhetsky, A.2    Allikmets, R.3
  • 17
    • 0031435428 scopus 로고    scopus 로고
    • Dye efflux studies suggest that hematopoietic stem cells expressing low or undetectable levels of CD34 antigen exist in multiple species
    • Goodell MA, Rosenzweig M, Kim H et al. Dye efflux studies suggest that hematopoietic stem cells expressing low or undetectable levels of CD34 antigen exist in multiple species. Nat. Med. 3(12), 1337-1345 (1997).
    • (1997) Nat. Med , vol.3 , Issue.12 , pp. 1337-1345
    • Goodell, M.A.1    Rosenzweig, M.2    Kim, H.3
  • 18
    • 68749099671 scopus 로고    scopus 로고
    • Identification of selective inhibitors of cancer stem cells by high-throughput screening
    • Gupta PB, Onder TT, Jiang G et al. Identification of selective inhibitors of cancer stem cells by high-throughput screening. Cell 138(4), 645-659 (2009).
    • (2009) Cell , vol.138 , Issue.4 , pp. 645-659
    • Gupta, P.B.1    Onder, T.T.2    Jiang, G.3
  • 19
    • 44049100934 scopus 로고    scopus 로고
    • Intrinsic resistance of tumorigenic breast cancer cells to chemotherapy
    • Li X, Lewis MT, Huang J et al. Intrinsic resistance of tumorigenic breast cancer cells to chemotherapy. J. Natl Cancer Inst. 100(9), 672-679 (2008).
    • (2008) J. Natl Cancer Inst , vol.100 , Issue.9 , pp. 672-679
    • Li, X.1    Lewis, M.T.2    Huang, J.3
  • 20
    • 64749093574 scopus 로고    scopus 로고
    • Association of reactive oxygen species levels and radioresistance in cancer stem cells
    • Diehn M, Cho RW, Lobo NA et al. Association of reactive oxygen species levels and radioresistance in cancer stem cells. Nature 458(7239), 780-783 (2009).
    • (2009) Nature , vol.458 , Issue.7239 , pp. 780-783
    • Diehn, M.1    Cho, R.W.2    Lobo, N.A.3
  • 21
    • 33846239456 scopus 로고    scopus 로고
    • Beyond tumorigenesis: Cancer stem cells in metastasis
    • Li F, Tiede B, Massagué J, Kang Y. Beyond tumorigenesis: cancer stem cells in metastasis. Cell Res. 17(1), 3-14 (2007).
    • (2007) Cell Res , vol.17 , Issue.1 , pp. 3-14
    • Li, F.1    Tiede, B.2    Massagué, J.3    Kang, Y.4
  • 22
    • 9144269759 scopus 로고    scopus 로고
    • Evidence that transgenes encoding components of the Wnt signaling pathway preferentially induce mammary cancers from progenitor cells
    • Li Y, Welm B, Podsypanina K et al. Evidence that transgenes encoding components of the Wnt signaling pathway preferentially induce mammary cancers from progenitor cells. Proc. Natl Acad. Sci. USA 100(26), 15853-15858 (2003).
    • (2003) Proc. Natl Acad. Sci. USA , vol.100 , Issue.26 , pp. 15853-15858
    • Li, Y.1    Welm, B.2    Podsypanina, K.3
  • 23
    • 34748837360 scopus 로고    scopus 로고
    • Networking of WNT, FGF, Notch, BMP, and Hedgehog signaling pathways during carcinogenesis
    • Katoh M. Networking of WNT, FGF, Notch, BMP, and Hedgehog signaling pathways during carcinogenesis. Stem Cell Rev. 3(1), 30-38 (2007).
    • (2007) Stem Cell Rev , vol.3 , Issue.1 , pp. 30-38
    • Katoh, M.1
  • 24
    • 77951975325 scopus 로고    scopus 로고
    • Wnt activity defines colon cancer stem cells and is regulated by the microenvironment
    • Vermeulen L, De Sousa E Melo F, van der Heijden M et al. Wnt activity defines colon cancer stem cells and is regulated by the microenvironment. Nat. Cell Biol. 12(5), 468-476 (2010).
    • (2010) Nat. Cell Biol , vol.12 , Issue.5 , pp. 468-476
    • Vermeulen, L.1    De Sousa Melo E, F.2    Van Der Heijden, M.3
  • 25
    • 79551631724 scopus 로고    scopus 로고
    • Network of WNT and other regulatory signaling cascades in pluripotent stem cells and cancer stem cells
    • Katoh M. Network of WNT and other regulatory signaling cascades in pluripotent stem cells and cancer stem cells. Curr. Pharm. Biotechnol. 12(2), 160-170 (2011).
    • (2011) Curr. Pharm. Biotechnol , vol.12 , Issue.2 , pp. 160-170
    • Katoh, M.1
  • 26
    • 43049165453 scopus 로고    scopus 로고
    • The epithelial-mesenchymal transition generates cells with properties of stem cells
    • Mani SA, Guo W, Liao MJ et al. The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell 133(4), 704-715 (2008).
    • (2008) Cell , vol.133 , Issue.4 , pp. 704-715
    • Mani, S.A.1    Guo, W.2    Liao, M.J.3
  • 27
    • 51449085561 scopus 로고    scopus 로고
    • Generation of breast cancer stem cells through epithelial-mesenchymal transition
    • Morel AP, Lièvre M, Thomas C, Hinkal G, Ansieau S, Puisieux A. Generation of breast cancer stem cells through epithelial-mesenchymal transition. PLoS ONE 3(8), e2888 (2008).
    • (2008) PLoS ONE , vol.3 , Issue.8
    • Morel, A.P.1    Lièvre, M.2    Thomas, C.3    Hinkal, G.4    Ansieau, S.5    Puisieux, A.6
  • 28
    • 0036569877 scopus 로고    scopus 로고
    • The pathology of familial breast cancer: Predictive value of immunohistochemical markers estrogen receptor, progesterone receptor, HER-2, and p53 in patients with mutations in BRCA1 and BRCA2
    • Lakhani SR, Van De Vijver MJ, Jacquemier J et al. The pathology of familial breast cancer: predictive value of immunohistochemical markers estrogen receptor, progesterone receptor, HER-2, and p53 in patients with mutations in BRCA1 and BRCA2. J. Clin. Oncol. 20(9), 2310-2318 (2002).
    • (2002) J. Clin. Oncol , vol.20 , Issue.9 , pp. 2310-2318
    • Lakhani, S.R.1    Van De Vijver, M.J.2    Jacquemier, J.3
  • 29
    • 34247569300 scopus 로고    scopus 로고
    • Descriptive analysis of estrogen receptor (ER)-negative, progesterone receptor (PR)-negative, and HER2-negative invasive breast cancer, the so-called triple-negative phenotype: A population-based study from the California Cancer Registry
    • Bauer KR, Brown M, Cress RD, Parise CA, Caggiano V. Descriptive analysis of estrogen receptor (ER)-negative, progesterone receptor (PR)-negative, and HER2-negative invasive breast cancer, the so-called triple-negative phenotype: a population-based study from the California Cancer Registry. Cancer 109(9), 1721-1728 (2007).
    • (2007) Cancer , vol.109 , Issue.9 , pp. 1721-1728
    • Bauer, K.R.1    Brown, M.2    Cress, R.D.3    Parise, C.A.4    Caggiano, V.5
  • 30
    • 68249144780 scopus 로고    scopus 로고
    • Breast cancer subtypes based on ER/PR and Her2 expression: Comparison of clinicopathologic features and survival
    • Onitilo AA, Engel JM, Greenlee RT, Mukesh BN. Breast cancer subtypes based on ER/PR and Her2 expression: comparison of clinicopathologic features and survival. Clin. Med. Res. 7(1-2), 4-13 (2009).
    • (2009) Clin. Med. Res , vol.7 , Issue.1-2 , pp. 4-13
    • Onitilo, A.A.1    Engel, J.M.2    Greenlee, R.T.3    Mukesh, B.N.4
  • 31
    • 0037948854 scopus 로고    scopus 로고
    • In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells
    • Dontu G, Abdallah WM, Foley JM et al. In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells. Genes Dev. 17(10), 1253-1270 (2003).
    • (2003) Genes Dev , vol.17 , Issue.10 , pp. 1253-1270
    • Dontu, G.1    Abdallah, W.M.2    Foley, J.M.3
  • 32
    • 0027491410 scopus 로고
    • FGF regulates the proliferative fate of unipotent (neuronal) and bipotent (neuronal/astroglial) EGF-generated CNS progenitor cells
    • Vescovi AL, Reynolds BA, Fraser DD, Weiss S. bFGF regulates the proliferative fate of unipotent (neuronal) and bipotent (neuronal/astroglial) EGF-generated CNS progenitor cells. Neuron 11(5), 951-966 (1993).
    • (1993) Neuron , vol.11 , Issue.5 , pp. 951-966
    • Vescovi, A.L.1    Reynolds, B.A.2    Fraser, D.D.3    Weiss, S.4
  • 33
    • 0029983762 scopus 로고    scopus 로고
    • Clonal and population analyses demonstrate that an EGF-responsive mammalian embryonic CNS precursor is a stem cell
    • Reynolds BA, Weiss S. Clonal and population analyses demonstrate that an EGF-responsive mammalian embryonic CNS precursor is a stem cell. Dev. Biol. 175(1), 1-13 (1996).
    • (1996) Dev. Biol , vol.175 , Issue.1 , pp. 1-13
    • Reynolds, B.A.1    Weiss, S.2
  • 34
    • 55749106963 scopus 로고    scopus 로고
    • Mammosphere culture of metastatic breast cancer cells enriches for tumorigenic breast cancer cells
    • Grimshaw MJ, Cooper L, Papazisis K et al. Mammosphere culture of metastatic breast cancer cells enriches for tumorigenic breast cancer cells. Breast Cancer Res. 10(3), R52 (2008).
    • (2008) Breast Cancer Res , vol.10 , Issue.3
    • Grimshaw, M.J.1    Cooper, L.2    Papazisis, K.3
  • 36
    • 35848955428 scopus 로고    scopus 로고
    • ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome
    • Ginestier C, Hur MH, Charafe-Jauffret E et al. ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome. Cell Stem Cell 1(5), 555-567 (2007).
    • (2007) Cell Stem Cell , vol.1 , Issue.5 , pp. 555-567
    • Ginestier, C.1    Hur, M.H.2    Charafe-Jauffret, E.3
  • 37
    • 70349123829 scopus 로고    scopus 로고
    • The tumor suppressor p53 regulates polarity of self-renewing divisions in mammary stem cells
    • Cicalese A, Bonizzi G, Pasi CE et al. The tumor suppressor p53 regulates polarity of self-renewing divisions in mammary stem cells. Cell 138(6), 1083-1095 (2009).
    • (2009) Cell , vol.138 , Issue.6 , pp. 1083-1095
    • Cicalese, A.1    Bonizzi, G.2    Pasi, C.E.3
  • 38
    • 68749092099 scopus 로고    scopus 로고
    • The role of CD133 in the identification and characterisation of tumour-initiating cells in non-small-cell lung cancer
    • Tirino V, Camerlingo R, Franco R et al. The role of CD133 in the identification and characterisation of tumour-initiating cells in non-small-cell lung cancer. Eur. J. Cardiothorac. Surg. 36(3), 446-453 (2009).
    • (2009) Eur. J. Cardiothorac. Surg , vol.36 , Issue.3 , pp. 446-453
    • Tirino, V.1    Camerlingo, R.2    Franco, R.3
  • 39
    • 33745728170 scopus 로고    scopus 로고
    • Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells
    • Liu S, Dontu G, Mantle ID et al. Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells. Cancer Res. 66(12), 6063-6071 (2006).
    • (2006) Cancer Res , vol.66 , Issue.12 , pp. 6063-6071
    • Liu, S.1    Dontu, G.2    Mantle, I.D.3
  • 40
    • 60549111070 scopus 로고    scopus 로고
    • Breast cancer cell lines contain functional cancer stem cells with metastatic capacity and a distinct molecular signature
    • Charafe-Jauffret E, Ginestier C, Iovino F et al. Breast cancer cell lines contain functional cancer stem cells with metastatic capacity and a distinct molecular signature. Cancer Res. 69(4), 1302-1313 (2009).
    • (2009) Cancer Res , vol.69 , Issue.4 , pp. 1302-1313
    • Charafe-Jauffret, E.1    Ginestier, C.2    Iovino, F.3
  • 41
    • 78650732630 scopus 로고    scopus 로고
    • Estrogen expands breast cancer stem-like cells through paracrine FGF/Tbx3 signaling
    • Fillmore CM, Gupta PB, Rudnick JA et al. Estrogen expands breast cancer stem-like cells through paracrine FGF/Tbx3 signaling. Proc. Natl Acad. Sci. USA 107(50), 21737-21742 (2010).
    • (2010) Proc. Natl Acad. Sci. USA , vol.107 , Issue.50 , pp. 21737-21742
    • Fillmore, C.M.1    Gupta, P.B.2    Rudnick, J.A.3
  • 42
    • 77955754150 scopus 로고    scopus 로고
    • Musashi1 regulates breast tumor cell proliferation and is a prognostic indicator of poor survival
    • Wang XY, Penalva LO, Yuan H et al. Musashi1 regulates breast tumor cell proliferation and is a prognostic indicator of poor survival. Mol. Cancer 9, 221 (2010).
    • (2010) Mol. Cancer , vol.9 , Issue.221
    • Wang, X.Y.1    Penalva, L.O.2    Yuan, H.3
  • 43
    • 78650389774 scopus 로고    scopus 로고
    • Coexpression of Oct4 and Nanog enhances malignancy in lung adenocarcinoma by inducing cancer stem cell-like properties and epithelial-mesenchymal transdifferentiation
    • Chiou SH, Wang ML, Chou YT et al. Coexpression of Oct4 and Nanog enhances malignancy in lung adenocarcinoma by inducing cancer stem cell-like properties and epithelial-mesenchymal transdifferentiation. Cancer Res. 70(24), 10433-10444 (2010).
    • (2010) Cancer Res , vol.70 , Issue.24 , pp. 10433-10444
    • Chiou, S.H.1    Wang, M.L.2    Chou, Y.T.3
  • 44
    • 77953765387 scopus 로고    scopus 로고
    • Doxorubicin in combination with a small TGF-β inhibitor: A potential novel therapy for metastatic breast cancer in mouse models
    • Bandyopadhyay A, Wang L, Agyin J et al. Doxorubicin in combination with a small TGF-β inhibitor: a potential novel therapy for metastatic breast cancer in mouse models. PLoS ONE 5(4), e10365 (2010).
    • (2010) PLoS ONE , vol.5 , Issue.4
    • Bandyopadhyay, A.1    Wang, L.2    Agyin, J.3
  • 45
    • 77951730125 scopus 로고    scopus 로고
    • Sulforaphane, a dietary component of broccoli/broccoli sprouts, inhibits breast cancer stem cells
    • Li Y, Zhang T, Korkaya H et al. Sulforaphane, a dietary component of broccoli/broccoli sprouts, inhibits breast cancer stem cells. Clin. Cancer Res. 16(9), 2580-2590 (2010).
    • (2010) Clin. Cancer Res , vol.16 , Issue.9 , pp. 2580-2590
    • Li, Y.1    Zhang, T.2    Korkaya, H.3
  • 46
    • 78149487540 scopus 로고    scopus 로고
    • Breast cancer stem-like cells are inhibited by a non-toxic aryl hydrocarbon receptor agonist
    • Prud'homme GJ, Glinka Y, Toulina A, Ace O, Subramaniam V, Jothy S. Breast cancer stem-like cells are inhibited by a non-toxic aryl hydrocarbon receptor agonist. PLoS ONE 5(11), e13831 (2010).
    • (2010) PLoS ONE , vol.5 , Issue.11
    • Prud'Homme, G.J.1    Glinka, Y.2    Toulina, A.3    Ace, O.4    Subramaniam, V.5    Jothy, S.6
  • 47
    • 77954517161 scopus 로고    scopus 로고
    • New-generation taxoid SB-T-1214 inhibits stem cell-related gene expression in 3D cancer spheroids induced by purified colon tumor-initiating cells
    • Botchkina GI, Zuniga ES, Das M et al. New-generation taxoid SB-T-1214 inhibits stem cell-related gene expression in 3D cancer spheroids induced by purified colon tumor-initiating cells. Mol. Cancer 9, 192 (2010).
    • (2010) Mol. Cancer , vol.9 , Issue.192
    • Botchkina, G.I.1    Zuniga, E.S.2    Das, M.3
  • 48
    • 37549002543 scopus 로고    scopus 로고
    • Isolation of rare circulating tumour cells in cancer patients by microchip technology
    • Nagrath S, Sequist LV, Maheswaran S et al. Isolation of rare circulating tumour cells in cancer patients by microchip technology. Nature 450(7173), 1235-1239 (2007).
    • (2007) Nature , vol.450 , Issue.7173 , pp. 1235-1239
    • Nagrath, S.1    Sequist, L.V.2    Maheswaran, S.3
  • 49
    • 46949084705 scopus 로고    scopus 로고
    • Highly efficient circulating tumor cell isolation from whole blood and label-free enumeration using polymer-based microfluidics with an integrated conductivity sensor
    • Adams AA, Okagbare PI, Feng J et al. Highly efficient circulating tumor cell isolation from whole blood and label-free enumeration using polymer-based microfluidics with an integrated conductivity sensor. J. Am. Chem. Soc. 130(27), 8633-8641 (2008).
    • (2008) J. Am. Chem. Soc , vol.130 , Issue.27 , pp. 8633-8641
    • Adams, A.A.1    Okagbare, P.I.2    Feng, J.3
  • 50
    • 62649158232 scopus 로고    scopus 로고
    • Isolating highly enriched populations of circulating epithelial cells and other rare cells from blood using a magnetic sweeper device
    • Talasaz AH, Powell AA, Huber DE et al. Isolating highly enriched populations of circulating epithelial cells and other rare cells from blood using a magnetic sweeper device. Proc. Natl Acad. Sci. USA 106(10), 3970-3975 (2009).
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , Issue.10 , pp. 3970-3975
    • Talasaz, A.H.1    Powell, A.A.2    Huber, D.E.3
  • 51
    • 77957075043 scopus 로고    scopus 로고
    • Microfluidic sorting and multimodal typing of cancer cells in self-assembled magnetic arrays
    • Saliba AE, Saias L, Psychari E et al. Microfluidic sorting and multimodal typing of cancer cells in self-assembled magnetic arrays. Proc. Natl Acad. Sci. USA 107(33), 14524-14529 (2010).
    • (2010) Proc. Natl Acad. Sci. USA , vol.107 , Issue.33 , pp. 14524-14529
    • Saliba, A.E.1    Saias, L.2    Psychari, E.3
  • 52
    • 78649872067 scopus 로고    scopus 로고
    • Isolation of circulating tumor cells using a microvortex-generating herringbone-chip
    • Stott SL, Hsu CH, Tsukrov DI et al. Isolation of circulating tumor cells using a microvortex-generating herringbone-chip. Proc. Natl Acad. Sci. USA 107(43), 18392-18397 (2010).
    • (2010) Proc. Natl Acad. Sci. USA , vol.107 , Issue.43 , pp. 18392-18397
    • Stott, S.L.1    Hsu, C.H.2    Tsukrov, D.I.3
  • 53
    • 0038271868 scopus 로고    scopus 로고
    • From latent disseminated cells to overt metastasis: Genetic analysis of systemic breast cancer progression
    • Schmidt-Kittler O, Ragg T, Daskalakis A et al. From latent disseminated cells to overt metastasis: genetic analysis of systemic breast cancer progression. Proc. Natl Acad. Sci. USA 100(13), 7737-7742 (2003).
    • (2003) Proc. Natl Acad. Sci. USA , vol.100 , Issue.13 , pp. 7737-7742
    • Schmidt-Kittler, O.1    Ragg, T.2    Daskalakis, A.3
  • 54
    • 19944426264 scopus 로고    scopus 로고
    • Circulating tumor cells in patients with breast cancer dormancy
    • Meng S, Tripathy D, Frenkel EP et al. Circulating tumor cells in patients with breast cancer dormancy. Clin. Cancer Res. 10(24), 8152-8162 (2004).
    • (2004) Clin. Cancer Res , vol.10 , Issue.24 , pp. 8152-8162
    • Meng, S.1    Tripathy, D.2    Frenkel, E.P.3
  • 55
    • 33751272999 scopus 로고    scopus 로고
    • Circulating tumor cells versus imaging-predicting overall survival in metastatic breast cancer
    • Budd GT, Cristofanilli M, Ellis MJ et al. Circulating tumor cells versus imaging-predicting overall survival in metastatic breast cancer. Clin. Cancer Res. 12(21), 6403-6409 (2006).
    • (2006) Clin. Cancer Res , vol.12 , Issue.21 , pp. 6403-6409
    • Budd, G.T.1    Cristofanilli, M.2    Ellis, M.J.3
  • 56
    • 30644463401 scopus 로고    scopus 로고
    • The measurement and therapeutic implications of circulating tumour cells in breast cancer
    • Smerage JB, Hayes DF. The measurement and therapeutic implications of circulating tumour cells in breast cancer. Br. J. Cancer 94(1), 8-12 (2006).
    • (2006) Br. J. Cancer , vol.94 , Issue.1 , pp. 8-12
    • Smerage, J.B.1    Hayes, D.F.2
  • 57
    • 33645688204 scopus 로고    scopus 로고
    • HER2-positive circulating tumor cells indicate poor clinical outcome in stage i to III breast cancer patients
    • Wülfing P, Borchard J, Buerger H et al. HER2-positive circulating tumor cells indicate poor clinical outcome in stage I to III breast cancer patients. Clin. Cancer Res. 12(6), 1715-1720 (2006).
    • (2006) Clin. Cancer Res , vol.12 , Issue.6 , pp. 1715-1720
    • Wülfing, P.1    Borchard, J.2    Buerger, H.3
  • 58
    • 34347353063 scopus 로고    scopus 로고
    • Circulating tumor cells (CTC) detection: Clinical impact and future directions
    • Paterlini-Brechot P, Benali NL. Circulating tumor cells (CTC) detection: clinical impact and future directions. Cancer Lett. 253(2), 180-204 (2007).
    • (2007) Cancer Lett , vol.253 , Issue.2 , pp. 180-204
    • Paterlini-Brechot, P.1    Benali, N.L.2
  • 59
    • 49249130844 scopus 로고    scopus 로고
    • Relationship of circulating tumor cells to tumor response, progression-free survival, and overall survival in patients with metastatic colorectal cancer
    • Cohen SJ, Punt CJ, Iannotti N et al. Relationship of circulating tumor cells to tumor response, progression-free survival, and overall survival in patients with metastatic colorectal cancer. J. Clin. Oncol. 26(19), 3213-3221 (2008).
    • (2008) J. Clin. Oncol , vol.26 , Issue.19 , pp. 3213-3221
    • Cohen, S.J.1    Punt, C.J.2    Iannotti, N.3
  • 60
    • 47949114668 scopus 로고    scopus 로고
    • Detection of mutations in EGFR in circulating lung-cancer cells
    • Maheswaran S, Sequist LV, Nagrath S et al. Detection of mutations in EGFR in circulating lung-cancer cells. N. Engl. J. Med. 359(4), 366-377 (2008).
    • (2008) N. Engl. J. Med , vol.359 , Issue.4 , pp. 366-377
    • Maheswaran, S.1    Sequist, L.V.2    Nagrath, S.3
  • 61
    • 33747086959 scopus 로고    scopus 로고
    • Microfluidic diagnostic technologies for global public health
    • Yager P, Edwards T, Fu E et al. Microfluidic diagnostic technologies for global public health. Nature 442(7101), 412-418 (2006).
    • (2006) Nature , vol.442 , Issue.7101 , pp. 412-418
    • Yager, P.1    Edwards, T.2    Fu, E.3
  • 62
    • 33845910922 scopus 로고    scopus 로고
    • Lab-on-a-chip devices for global health: Past studies and future opportunities
    • Chin CD, Linder V, Sia SK. Lab-on-a-chip devices for global health: past studies and future opportunities. Lab Chip 7(1), 41-57 (2007).
    • (2007) Lab Chip , vol.7 , Issue.1 , pp. 41-57
    • Chin, C.D.1    Linder, V.2    Sia, S.K.3
  • 63
    • 56549083018 scopus 로고    scopus 로고
    • Innovations in optical microfluidic technologies for point-of-care diagnostics
    • Myers FB, Lee LP. Innovations in optical microfluidic technologies for point-of-care diagnostics. Lab Chip 8(12), 2015-2031 (2008).
    • (2008) Lab Chip , vol.8 , Issue.12 , pp. 2015-2031
    • Myers, F.B.1    Lee, L.P.2
  • 64
    • 78049323690 scopus 로고    scopus 로고
    • A self-contained all-in-one cartridge for sample preparation and real-time PCR in rapid influenza diagnosis
    • Xu G, Hsieh TM, Lee DY et al. A self-contained all-in-one cartridge for sample preparation and real-time PCR in rapid influenza diagnosis. Lab Chip 10(22), 3103-3111 (2010).
    • (2010) Lab Chip , vol.10 , Issue.22 , pp. 3103-3111
    • Xu, G.1    Hsieh, T.M.2    Lee, D.Y.3
  • 65
    • 79953208676 scopus 로고    scopus 로고
    • A lab-on-a-chip device for rapid identification of avian influenza viral RNA by solid-phase PCR
    • Sun Y, Dhumpa R, Bang DD, Høgberg J, Handberg K, Wolff A. A lab-on-a-chip device for rapid identification of avian influenza viral RNA by solid-phase PCR. Lab Chip 11(8), 1457-1463 (2011).
    • (2011) Lab Chip , vol.11 , Issue.8 , pp. 1457-1463
    • Sun, Y.1    Dhumpa, R.2    Bang, D.D.3    Høgberg, J.4    Handberg, K.5    Wolff, A.6
  • 66
    • 79953198644 scopus 로고    scopus 로고
    • A magnetic bead-based assay for the rapid detection of methicillin-resistant Staphylococcus aureus by using a microfluidic system with integrated loop-mediated isothermal amplification
    • Wang CH, Lien KY, Wu JJ, Lee GB. A magnetic bead-based assay for the rapid detection of methicillin-resistant Staphylococcus aureus by using a microfluidic system with integrated loop-mediated isothermal amplification. Lab Chip 11(8), 1521-1531 (2011).
    • (2011) Lab Chip , vol.11 , Issue.8 , pp. 1521-1531
    • Wang, C.H.1    Lien, K.Y.2    Wu, J.J.3    Lee, G.B.4
  • 67
    • 84863654651 scopus 로고    scopus 로고
    • Detection of influenza virus using a lateral flow immunoassay for amplified DNA by a microfluidic RT-PCR chip
    • Nagatani N, Yamanaka K, Ushijima H et al. Detection of influenza virus using a lateral flow immunoassay for amplified DNA by a microfluidic RT-PCR chip. Analyst 137(15), 3422-3426 (2012).
    • (2012) Analyst , vol.137 , Issue.15 , pp. 3422-3426
    • Nagatani, N.1    Yamanaka, K.2    Ushijima, H.3
  • 68
    • 84855820777 scopus 로고    scopus 로고
    • A novel real time micro PCR based point-of-care device for Salmonella detection in human clinical samples
    • Verdoy D, Barrenetxea Z, Berganzo J et al. A novel real time micro PCR based point-of-care device for Salmonella detection in human clinical samples. Biosens. Bioelectron. 32(1), 259-265 (2012).
    • (2012) Biosens. Bioelectron , vol.32 , Issue.1 , pp. 259-265
    • Verdoy, D.1    Barrenetxea, Z.2    Berganzo, J.3
  • 69
    • 27144513329 scopus 로고    scopus 로고
    • Multiplexed electrical detection of cancer markers with nanowire sensor arrays
    • Zheng G, Patolsky F, Cui Y, Wang WU, Lieber CM. Multiplexed electrical detection of cancer markers with nanowire sensor arrays. Nat. Biotechnol. 23(10), 1294-1301 (2005).
    • (2005) Nat. Biotechnol , vol.23 , Issue.10 , pp. 1294-1301
    • Zheng, G.1    Patolsky, F.2    Cui, Y.3    Wang, W.U.4    Lieber, C.M.5
  • 70
    • 57449085941 scopus 로고    scopus 로고
    • Integrated barcode chips for rapid, multiplexed analysis of proteins in microliter quantities of blood
    • Fan R, Vermesh O, Srivastava A et al. Integrated barcode chips for rapid, multiplexed analysis of proteins in microliter quantities of blood. Nat. Biotechnol. 26(12), 1373-1378 (2008).
    • (2008) Nat. Biotechnol , vol.26 , Issue.12 , pp. 1373-1378
    • Fan, R.1    Vermesh, O.2    Srivastava, A.3
  • 71
    • 56549086851 scopus 로고    scopus 로고
    • Enabling a microfluidic immunoassay for the developing world by integration of on-card dry reagent storage
    • Stevens DY, Petri CR, Osborn JL, Spicar-Mihalic P, McKenzie KG, Yager P. Enabling a microfluidic immunoassay for the developing world by integration of on-card dry reagent storage. Lab Chip 8(12), 2038-2045 (2008).
    • (2008) Lab Chip , vol.8 , Issue.12 , pp. 2038-2045
    • Stevens, D.Y.1    Petri, C.R.2    Osborn, J.L.3    Spicar-Mihalic, P.4    McKenzie, K.G.5    Yager, P.6
  • 72
    • 66149108280 scopus 로고    scopus 로고
    • A fully automated immunoassay from whole blood on a disc
    • Lee BS, Lee JN, Park JM et al. A fully automated immunoassay from whole blood on a disc. Lab Chip 9(11), 1548-1555 (2009).
    • (2009) Lab Chip , vol.9 , Issue.11 , pp. 1548-1555
    • Lee, B.S.1    Lee, J.N.2    Park, J.M.3
  • 73
    • 75749143500 scopus 로고    scopus 로고
    • Quantitative, label-free detection of five protein biomarkers using multiplexed arrays of silicon photonic microring resonators
    • Washburn AL, Luchansky MS, Bowman AL, Bailey RC. Quantitative, label-free detection of five protein biomarkers using multiplexed arrays of silicon photonic microring resonators. Anal. Chem. 82(1), 69-72 (2010).
    • (2010) Anal. Chem , vol.82 , Issue.1 , pp. 69-72
    • Washburn, A.L.1    Luchansky, M.S.2    Bowman, A.L.3    Bailey, R.C.4
  • 74
    • 76949085304 scopus 로고    scopus 로고
    • Parallel microfluidic surface plasmon resonance imaging arrays
    • Ouellet E, Lausted C, Lin T, Yang CW, Hood L, Lagally ET. Parallel microfluidic surface plasmon resonance imaging arrays. Lab Chip 10(5), 581-588 (2010).
    • (2010) Lab Chip , vol.10 , Issue.5 , pp. 581-588
    • Ouellet, E.1    Lausted, C.2    Lin, T.3    Yang, C.W.4    Hood, L.5    Lagally, E.T.6
  • 75
    • 84855675521 scopus 로고    scopus 로고
    • Highly-integrated lab-on-chip system for point-of-care multiparameter analysis
    • Schumacher S, Nestler J, Otto T et al. Highly-integrated lab-on-chip system for point-of-care multiparameter analysis. Lab Chip 12(3), 464-473 (2012).
    • (2012) Lab Chip , vol.12 , Issue.3 , pp. 464-473
    • Schumacher, S.1    Nestler, J.2    Otto, T.3
  • 76
    • 79954445220 scopus 로고    scopus 로고
    • Solid phase extraction of DNA from biological samples in a post-based, high surface area poly(methyl methacrylate) (PMMA) microdevice
    • Reedy CR, Price CW, Sniegowski J, Ferrance JP, Begley M, Landers JP. Solid phase extraction of DNA from biological samples in a post-based, high surface area poly(methyl methacrylate) (PMMA) microdevice. Lab Chip 11(9), 1603-1611 (2011).
    • (2011) Lab Chip , vol.11 , Issue.9 , pp. 1603-1611
    • Reedy, C.R.1    Price, C.W.2    Sniegowski, J.3    Ferrance, J.P.4    Begley, M.5    Landers, J.P.6
  • 77
    • 79952137711 scopus 로고    scopus 로고
    • Purification of HIV RNA from serum using a polymer capture matrix in a microfluidic device
    • Root BE, Agarwal AK, Kelso DM, Barron AE. Purification of HIV RNA from serum using a polymer capture matrix in a microfluidic device. Anal. Chem. 83(3), 982-988 (2011).
    • (2011) Anal. Chem , vol.83 , Issue.3 , pp. 982-988
    • Root, B.E.1    Agarwal, A.K.2    Kelso, D.M.3    Barron, A.E.4
  • 78
    • 77249096429 scopus 로고    scopus 로고
    • Characterization of dynamic solid phase DNA extraction from blood with magnetically controlled silica beads
    • Duarte GR, Price CW, Littlewood JL et al. Characterization of dynamic solid phase DNA extraction from blood with magnetically controlled silica beads. Analyst 135(3), 531-537 (2010).
    • (2010) Analyst , vol.135 , Issue.3 , pp. 531-537
    • Duarte, G.R.1    Price, C.W.2    Littlewood, J.L.3
  • 79
    • 70349331519 scopus 로고    scopus 로고
    • Nucleic acid extraction techniques and application to the microchip
    • Price CW, Leslie DC, Landers JP. Nucleic acid extraction techniques and application to the microchip. Lab Chip 9(17), 2484-2494 (2009).
    • (2009) Lab Chip , vol.9 , Issue.17 , pp. 2484-2494
    • Price, C.W.1    Leslie, D.C.2    Landers, J.P.3
  • 80
    • 52649108805 scopus 로고    scopus 로고
    • Quantitative and qualitative analysis of a microfluidic DNA extraction system using a nanoporous AlO(x) membrane
    • Kim J, Gale BK. Quantitative and qualitative analysis of a microfluidic DNA extraction system using a nanoporous AlO(x) membrane. Lab Chip 8(9), 1516-1523 (2008).
    • (2008) Lab Chip , vol.8 , Issue.9 , pp. 1516-1523
    • Kim, J.1    Gale, B.K.2
  • 81
    • 34247873038 scopus 로고    scopus 로고
    • One-step pathogen specific DNA extraction from whole blood on a centrifugal microfluidic device
    • Cho YK, Lee JG, Park JM, Lee BS, Lee Y, Ko C. One-step pathogen specific DNA extraction from whole blood on a centrifugal microfluidic device. Lab Chip 7(5), 565-573 (2007).
    • (2007) Lab Chip , vol.7 , Issue.5 , pp. 565-573
    • Cho, Y.K.1    Lee, J.G.2    Park, J.M.3    Lee, B.S.4    Lee, Y.5    Ko, C.6
  • 82
    • 0035866594 scopus 로고    scopus 로고
    • Generation of gradients having complex shapes using microfluidic networks
    • Dertinger SKW, Chiu DT, Jeon NL, Whitesides GM. Generation of gradients having complex shapes using microfluidic networks. Anal. Chem. 73(6), 1240-1246 (2001).
    • (2001) Anal. Chem , vol.73 , Issue.6 , pp. 1240-1246
    • Skw, D.1    Chiu, D.T.2    Jeon, N.L.3    Whitesides, G.M.4
  • 83
    • 0036022527 scopus 로고    scopus 로고
    • Neutrophil chemotaxis in linear and complex gradients of interleukin-8 formed in a microfabricated device
    • Li Jeon N, Baskaran H, Dertinger SK, Whitesides GM, Van de Water L, Toner M. Neutrophil chemotaxis in linear and complex gradients of interleukin-8 formed in a microfabricated device. Nat. Biotechnol. 20(8), 826-830 (2002).
    • (2002) Nat. Biotechnol , vol.20 , Issue.8 , pp. 826-830
    • Li Jeon, N.1    Baskaran, H.2    Dertinger, S.K.3    Whitesides, G.M.4    Van De Water, L.5    Toner, M.6
  • 84
    • 59649105005 scopus 로고    scopus 로고
    • A multipurpose microfluidic device designed to mimic microenvironment gradients and develop targeted cancer therapeutics
    • Walsh CL, Babin BM, Kasinskas RW, Foster JA, McGarry MJ, Forbes NS. A multipurpose microfluidic device designed to mimic microenvironment gradients and develop targeted cancer therapeutics. Lab Chip 9(4), 545-554 (2009).
    • (2009) Lab Chip , vol.9 , Issue.4 , pp. 545-554
    • Walsh, C.L.1    Babin, B.M.2    Kasinskas, R.W.3    Foster, J.A.4    McGarry, M.J.5    Forbes, N.S.6
  • 85
    • 84055207544 scopus 로고    scopus 로고
    • A robust diffusion-based gradient generator for dynamic cell assays
    • Atencia J, Cooksey GA, Locascio LE. A robust diffusion-based gradient generator for dynamic cell assays. Lab Chip 12(2), 309-316 (2012).
    • (2012) Lab Chip , vol.12 , Issue.2 , pp. 309-316
    • Atencia, J.1    Cooksey, G.A.2    Locascio, L.E.3
  • 86
    • 77957754885 scopus 로고    scopus 로고
    • Tumors on chips: Oncology meets microfluidics
    • Wlodkowic D, Cooper JM. Tumors on chips: oncology meets microfluidics. Curr. Opin. Chem. Biol. 14(5), 556-567 (2010).
    • (2010) Curr. Opin. Chem. Biol , vol.14 , Issue.5 , pp. 556-567
    • Wlodkowic, D.1    Cooper, J.M.2
  • 87
    • 77952499476 scopus 로고    scopus 로고
    • Fundamentals of microfluidic cell culture in controlled microenvironments
    • Young EW, Beebe DJ. Fundamentals of microfluidic cell culture in controlled microenvironments. Chem. Soc. Rev. 39(3), 1036-1048 (2010).
    • (2010) Chem. Soc. Rev , vol.39 , Issue.3 , pp. 1036-1048
    • Young, E.W.1    Beebe, D.J.2
  • 89
    • 77950438544 scopus 로고    scopus 로고
    • Microfluidic cell culture systems for drug research
    • Wu MH, Huang SB, Lee GB. Microfluidic cell culture systems for drug research. Lab Chip 10(8), 939-956 (2010).
    • (2010) Lab Chip , vol.10 , Issue.8 , pp. 939-956
    • Wu, M.H.1    Huang, S.B.2    Lee, G.B.3
  • 90
    • 65649133932 scopus 로고    scopus 로고
    • A micro cell culture analog (microCCA) with 3-D hydrogel culture of multiple cell lines to assess metabolism-dependent cytotoxicity of anti-cancer drugs
    • Sung JH, Shuler ML. A micro cell culture analog (microCCA) with 3-D hydrogel culture of multiple cell lines to assess metabolism-dependent cytotoxicity of anti-cancer drugs. Lab Chip 9(10), 1385-1394 (2009).
    • (2009) Lab Chip , vol.9 , Issue.10 , pp. 1385-1394
    • Sung, J.H.1    Shuler, M.L.2
  • 91
    • 63649097667 scopus 로고    scopus 로고
    • Microfluidic system for formation of PC-3 prostate cancer co-culture spheroids
    • Hsiao AY, Torisawa YS, Tung YC et al. Microfluidic system for formation of PC-3 prostate cancer co-culture spheroids. Biomaterials 30(16), 3020-3027 (2009).
    • (2009) Biomaterials , vol.30 , Issue.16 , pp. 3020-3027
    • Hsiao, A.Y.1    Torisawa, Y.S.2    Tung, Y.C.3
  • 92
    • 42549106741 scopus 로고    scopus 로고
    • Automated cell culture in high density tubeless microfluidic device arrays
    • Meyvantsson I, Warrick JW, Hayes S, Skoien A, Beebe DJ. Automated cell culture in high density tubeless microfluidic device arrays. Lab Chip 8(5), 717-724 (2008).
    • (2008) Lab Chip , vol.8 , Issue.5 , pp. 717-724
    • Meyvantsson, I.1    Warrick, J.W.2    Hayes, S.3    Skoien, A.4    Beebe, D.J.5
  • 93
    • 84863276263 scopus 로고    scopus 로고
    • Openly accessible microfluidic liquid handlers for automated high-throughput nanoliter cell culture
    • Zhou Y, Pang Y, Huang Y. Openly accessible microfluidic liquid handlers for automated high-throughput nanoliter cell culture. Anal. Chem. 84(5), 2576-2584 (2012).
    • (2012) Anal. Chem , vol.84 , Issue.5 , pp. 2576-2584
    • Zhou, Y.1    Pang, Y.2    Huang, Y.3
  • 94
    • 0029078999 scopus 로고
    • A microplate assay for quantitation of anchorage-independent growth of transformed cells
    • Fukazawa H, Mizuno S, Uehara Y. A microplate assay for quantitation of anchorage-independent growth of transformed cells. Anal. Biochem. 228(1), 83-90 (1995).
    • (1995) Anal. Biochem , vol.228 , Issue.1 , pp. 83-90
    • Fukazawa, H.1    Mizuno, S.2    Uehara, Y.3
  • 95
    • 0026351910 scopus 로고
    • Self-assembled organic monolayers: Model systems for studying adsorption of proteins at surfaces
    • Prime KL, Whitesides GM. Self-assembled organic monolayers: model systems for studying adsorption of proteins at surfaces. Science 252(5010), 1164-1167 (1991).
    • (1991) Science , vol.252 , Issue.5010 , pp. 1164-1167
    • Prime, K.L.1    Whitesides, G.M.2
  • 96
    • 0032170720 scopus 로고    scopus 로고
    • Protein-resistant coatings for glass and metal oxide surfaces derived from oligo(ethylene glycol)-terminated alkytrichlorosilanes
    • Lee SW, Laibinis PE. Protein-resistant coatings for glass and metal oxide surfaces derived from oligo(ethylene glycol)-terminated alkytrichlorosilanes. Biomaterials 19(18), 1669-1675 (1998).
    • (1998) Biomaterials , vol.19 , Issue.18 , pp. 1669-1675
    • Lee, S.W.1    Laibinis, P.E.2
  • 97
    • 0345015908 scopus 로고    scopus 로고
    • Surface engineering with poly(ethylene glycol) photolithography to create high-density cell arrays on glass
    • Revzin A, Tompkins RG, Toner M. Surface engineering with poly(ethylene glycol) photolithography to create high-density cell arrays on glass. Langmuir 19(13), 9855-9862 (2003).
    • (2003) Langmuir , vol.19 , Issue.13 , pp. 9855-9862
    • Revzin, A.1    Tompkins, R.G.2    Toner, M.3
  • 98
    • 33845991206 scopus 로고    scopus 로고
    • Modulation of chondrocyte phenotype for tissue engineering by designing the biologic-polymer carrier interface
    • Mahmood TA, Miot S, Frank O et al. Modulation of chondrocyte phenotype for tissue engineering by designing the biologic-polymer carrier interface. Biomacromolecules 7(11), 3012-3018 (2006).
    • (2006) Biomacromolecules , vol.7 , Issue.11 , pp. 3012-3018
    • Mahmood, T.A.1    Miot, S.2    Frank, O.3
  • 99
    • 34247131744 scopus 로고    scopus 로고
    • Effect of wettability and surface functional groups on protein adsorption and cell adhesion using well-defined mixed self-assembled monolayers
    • Arima Y, Iwata H. Effect of wettability and surface functional groups on protein adsorption and cell adhesion using well-defined mixed self-assembled monolayers. Biomaterials 28(20), 3074-3082 (2007).
    • (2007) Biomaterials , vol.28 , Issue.20 , pp. 3074-3082
    • Arima, Y.1    Iwata, H.2
  • 100
    • 79955446412 scopus 로고    scopus 로고
    • Introducing RGD peptides on PHBV films through PEG-containing cross-linkers to improve the biocompatibility
    • Wang YY, Lü LX, Shi JC, Wang HF, Xiao ZD, Huang NP. Introducing RGD peptides on PHBV films through PEG-containing cross-linkers to improve the biocompatibility. Biomacromolecules 12(3), 551-559 (2011).
    • (2011) Biomacromolecules , vol.12 , Issue.3 , pp. 551-559
    • Wang, Y.Y.1    Lü, L.X.2    Shi, J.C.3    Wang, H.F.4    Xiao, Z.D.5    Huang, N.P.6
  • 101
    • 79952256268 scopus 로고    scopus 로고
    • 3-Dimensional cell culture for on-chip differentiation of stem cells in embryoid body
    • Kim C, Lee KS, Bang JH et al. 3-Dimensional cell culture for on-chip differentiation of stem cells in embryoid body. Lab Chip 11(5), 874-882 (2011).
    • (2011) Lab Chip , vol.11 , Issue.5 , pp. 874-882
    • Kim, C.1    Lee, K.S.2    Bang, J.H.3
  • 102
    • 77957682629 scopus 로고    scopus 로고
    • Development of a multi-layer microfluidic array chip to culture and replate uniform-sized embryoid bodies without manual cell retrieval
    • Kang E, Choi YY, Jun Y, Chung BG, Lee SH. Development of a multi-layer microfluidic array chip to culture and replate uniform-sized embryoid bodies without manual cell retrieval. Lab Chip 10(20), 2651-2654 (2010).
    • (2010) Lab Chip , vol.10 , Issue.20 , pp. 2651-2654
    • Kang, E.1    Choi, Y.Y.2    Jun, Y.3    Chung, B.G.4    Lee, S.H.5
  • 103
    • 33749510846 scopus 로고    scopus 로고
    • Deterministic hydrodynamics: Taking blood apart
    • Davis JA, Inglis DW, Morton KJ et al. Deterministic hydrodynamics: taking blood apart. Proc. Natl Acad. Sci. USA 103(40), 14779-14784 (2006).
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , Issue.40 , pp. 14779-14784
    • Davis, J.A.1    Inglis, D.W.2    Morton, K.J.3
  • 104
    • 35548941139 scopus 로고    scopus 로고
    • Continuous blood cell separation by hydrophoretic filtration
    • Choi S, Song S, Choi C, Park JK. Continuous blood cell separation by hydrophoretic filtration. Lab Chip 7(11), 1532-1538 (2007).
    • (2007) Lab Chip , vol.7 , Issue.11 , pp. 1532-1538
    • Choi, S.1    Song, S.2    Choi, C.3    Park, J.K.4
  • 105
    • 46149108592 scopus 로고    scopus 로고
    • Lateral-driven continuous dielectrophoretic microseparators for blood cells suspended in a highly conductive medium
    • Han KH, Frazier AB. Lateral-driven continuous dielectrophoretic microseparators for blood cells suspended in a highly conductive medium. Lab Chip 8(7), 1079-1086 (2008).
    • (2008) Lab Chip , vol.8 , Issue.7 , pp. 1079-1086
    • Han, K.H.1    Frazier, A.B.2
  • 106
    • 70350648675 scopus 로고    scopus 로고
    • Deterministic lateral displacement as a means to enrich large cells for tissue engineering
    • Green JV, Radisic M, Murthy SK. Deterministic lateral displacement as a means to enrich large cells for tissue engineering. Anal. Chem. 81(21), 9178-9182 (2009).
    • (2009) Anal. Chem , vol.81 , Issue.21 , pp. 9178-9182
    • Green, J.V.1    Radisic, M.2    Murthy, S.K.3
  • 107
    • 64749084287 scopus 로고    scopus 로고
    • Microfluidic self-sorting of mammalian cells to achieve cell cycle synchrony by hydrophoresis
    • Choi S, Song S, Choi C, Park JK. Microfluidic self-sorting of mammalian cells to achieve cell cycle synchrony by hydrophoresis. Anal. Chem. 81(5), 1964-1968 (2009).
    • (2009) Anal. Chem , vol.81 , Issue.5 , pp. 1964-1968
    • Choi, S.1    Song, S.2    Choi, C.3    Park, J.K.4
  • 108
    • 77952472317 scopus 로고    scopus 로고
    • Continuous separation of cells and particles in microfluidic systems
    • Lenshof A, Laurell T. Continuous separation of cells and particles in microfluidic systems. Chem. Soc. Rev. 39(3), 1203-1217 (2010).
    • (2010) Chem. Soc. Rev , vol.39 , Issue.3 , pp. 1203-1217
    • Lenshof, A.1    Laurell, T.2
  • 109
    • 79956371490 scopus 로고    scopus 로고
    • Pinched flow coupled shear-modulated inertial microfluidics for high-throughput rare blood cell separation
    • Bhagat AA, Hou HW, Li LD, Lim CT, Han J. Pinched flow coupled shear-modulated inertial microfluidics for high-throughput rare blood cell separation. Lab Chip 11(11), 1870-1878 (2011).
    • (2011) Lab Chip , vol.11 , Issue.11 , pp. 1870-1878
    • Bhagat, A.A.1    Hou, H.W.2    Li, L.D.3    Lim, C.T.4    Han, J.5
  • 110
    • 80051625833 scopus 로고    scopus 로고
    • Automated cellular sample preparation using a Centrifuge-on-a-Chip
    • Mach AJ, Kim JH, Arshi A, Hur SC, Di Carlo D. Automated cellular sample preparation using a Centrifuge-on-a-Chip. Lab Chip 11(17), 2827-2834 (2011).
    • (2011) Lab Chip , vol.11 , Issue.17 , pp. 2827-2834
    • MacH, A.J.1    Kim, J.H.2    Arshi, A.3    Hur, S.C.4    Di Carlo, D.5
  • 111
    • 79952134859 scopus 로고    scopus 로고
    • Continuous separation of breast cancer cells from blood samples using multi-orifice flow fractionation (MOFF) and dielectrophoresis (DEP
    • Moon HS, Kwon K, Kim SI et al. Continuous separation of breast cancer cells from blood samples using multi-orifice flow fractionation (MOFF) and dielectrophoresis (DEP). Lab Chip 11(6), 1118-1125 (2011).
    • (2011) Lab Chip , vol.11 , Issue.6 , pp. 1118-1125
    • Moon, H.S.1    Kwon, K.2    Kim, S.I.3
  • 112
    • 78751513021 scopus 로고    scopus 로고
    • Circulating tumor cells: The Grand Challenge
    • den Toonder J. Circulating tumor cells: the Grand Challenge. Lab Chip 11(3), 375-377 (2011).
    • (2011) Lab Chip , vol.11 , Issue.3 , pp. 375-377
    • Den Toonder, J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.