Sphingolipids as New Biomarkers for Assessment of Delayed-Type Hypersensitivity and Response to Triptolide

PLoS ONE

Volumn 7, Issue 12, 2012, Pages

  Qu, Feng ^a   Wu, Cai Sheng ^a   Hou, Jin Feng ^a   Jin, Ying ^a   Zhang, Jin Lan ^a  

^a INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

[No Author keywords available]

Indexed keywords

SPHINGOLIPID; TRIPTOLIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DELAYED HYPERSENSITIVITY; DISEASE ASSOCIATION; DISEASE MARKER; DRUG RESPONSE; DRUG STRUCTURE; EAR EDEMA; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; KIDNEY; LIPID ANALYSIS; LIPID BLOOD LEVEL; LIPID LIVER LEVEL; LIPIDOMICS; LYMPHATIC PARAMETERS; MALE; MOUSE; NONHUMAN; QUANTITATIVE ANALYSIS; SPLEEN; SPLENIC INDEX; TANDEM MASS SPECTROMETRY;

ANIMALS; BIOLOGICAL MARKERS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DINITROFLUOROBENZENE; DISEASE PROGRESSION; DITERPENES; EAR; EPOXY COMPOUNDS; HYPERSENSITIVITY, DELAYED; KIDNEY; MALE; MICE; MICE, INBRED BALB C; PHENANTHRENES; SPHINGOLIPIDS; SPLEEN; TANDEM MASS SPECTROMETRY; TREATMENT OUTCOME;

MUS;

EID: 84871546322     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0052454     Document Type: Article

References (47)

1. Hawthorne KM, Dana R, Chodosh J, (2011) Delayed type hypersensitivity in the pathogenesis of recurrent herpes stromal keratitis. Semin Ophthalmol 26: 246-250.
2. Adam J, Pichler WJ, Yerly D, (2011) Delayed drug hypersensitivity: models of T-cell stimulation. Br J Clin Pharmacol 71: 701-707.
3. Steenholdt C, Svenson M, Bendtzen K, Thomsen OO, Brynskov J, et al. (2012) Acute and delayed hypersensitivity reactions to infliximab and adalimumab in a patient with Crohn's disease. J Crohns Colitis 6: 108-111.
4. Gu WZ, Chen R, Brandwein S, McAlpine J, Burres N, (1995) Isolation, purification, and characterization of immunosuppressive compounds from tripterygium: triptolide and tripdiolide. Int J Immunopharmacol 17: 351-356.
5. Zeng R, Zeng L, Chen Y, Zhao F, Li R, et al. (2011) Triptolide-induced apoptosis by inactivating nuclear factor-kappa B apoptotic pathway in multiple myeloma in vitro. J Huazhong Univ Sci Technolog Med Sci 31: 446-451.
6. Tao R, Lu L, Zhang R, Hu J, Ni J, et al. (2011) Triptolide inhibits rat vascular smooth muscle cell proliferation and cell cycle progression via attenuation of ERK1/2 and Rb phosphorylation. Exp Mol Pathol 90: 137-142.
7. Hailong G, Yujie Z, Hanying M, Lei L, Xiaoli L, et al. (2011) Effectiveness of triptolide-coated stent on decreasing inflammation and attenuation of intimal hyperplasia in a pig after coronary angioplasty. Angiology 62: 265-269.
8. He MF, Huang YH, Wu LW, Ge W, Shaw PC, et al. (2010) Triptolide functions as a potent angiogenesis inhibitor. Int J Cancer 126: 266-278.
9. Zhang G, Liu Y, Guo H, Sun Z, Zhou YH, (2009) Triptolide promotes generation of FoxP3+ T regulatory cells in rats. J Ethnopharmacol 125: 41-46.
10. van Eden W, (2009) Protective and therapeutic effect of triptolide in EAE explained by induction of major stress protein HSP70. J Neuroimmunol 217: 10-11.
11. Liou JT, Chen ZY, Ho LJ, Yang SP, Chang DM, et al. (2008) Differential effects of triptolide and tetrandrine on activation of COX-2, NF-kappaB, and AP-1 and virus production in dengue virus-infected human lung cells. Eur J Pharmacol 589: 288-298.
12. Liang M, Fu J, (2008) Triptolide inhibits interferon-gamma-induced programmed death-1-ligand 1 surface expression in breast cancer cells. Cancer Lett 270: 337-341.
13. Leuenroth SJ, Bencivenga N, Igarashi P, Somlo S, Crews CM, (2008) Triptolide reduces cystogenesis in a model of ADPKD. J Am Soc Nephrol 19: 1659-1662.
14. Aoyagi Y, Hitotsuyanagi Y, Hasuda T, Matsuyama S, Fukaya H, et al. (2008) Fluorination of triptolide and its analogues and their cytotoxicity. Bioorg Med Chem Lett 18: 2459-2463.
15. Dan H, Peng RX, Ao Y, Liu YH, (2008) Segment-specific proximal tubule injury in tripterygium glycosides intoxicated rats. J Biochem Mol Toxicol 22: 422-428.
16. Yang F, Ren L, Zhuo L, Ananda S, Liu L (2011) Involvement of oxidative stress in the mechanism of triptolide-induced acute nephrotoxicity in rats. Exp Toxicol Pathol.
17. Merrill AH Jr, Stokes TH, Momin A, Park H, Portz BJ, et al. (2009) Sphingolipidomics: a valuable tool for understanding the roles of sphingolipids in biology and disease. J Lipid Res 50Suppl: S97-102.
18. Dyatlovitskaya EV, Kandyba AG, (2006) Sphingolipids in tumor metastases and angiogenesis. Biochemistry (Mosc) 71: 347-353.
19. Napolitano G, Karin M, (2010) Sphingolipids: the oil on the TRAFire that promotes inflammation. Sci Signal 3: pe34.
20. Jyonouchi S, Abraham V, Orange JS, Spergel JM, Gober L, et al. (2011) Invariant natural killer T cells from children with versus without food allergy exhibit differential responsiveness to milk-derived sphingomyelin. J Allergy Clin Immunol 128: 102-109 e113.
21. Jana A, Pahan K, (2010) Sphingolipids in multiple sclerosis. Neuromolecular Med 12: 351-361.
22. Lalazar G, Preston S, Zigmond E, Ben Yaacov A, Ilan Y, (2006) Glycolipids as immune modulatory tools. Mini Rev Med Chem 6: 1249-1253.
23. Mouritsen OG (2011) Lipidology and lipidomics-quo vadis? A new era for the physical chemistry of lipids. Phys Chem Chem Phys.
24. Bucci M, (2011) Lipidomics: A viral egress. Nat Chem Biol 7: 577-577.
25. de Grauw JC, van de Lest CH, van Weeren PR, (2011) A targeted lipidomics approach to the study of eicosanoid release in synovial joints. Arthritis Res Ther 13: R123.
26. Sullards MC, Allegood JC, Kelly S, Wang E, Haynes CA, et al. (2007) Structure-specific, quantitative methods for analysis of sphingolipids by liquid chromatography-tandem mass spectrometry: "inside-out" sphingolipidomics. Methods Enzymol 432: 83-115.
27. Merrill AH Jr, Sullards MC, Allegood JC, Kelly S, Wang E, (2005) Sphingolipidomics: high-throughput, structure-specific, and quantitative analysis of sphingolipids by liquid chromatography tandem mass spectrometry. Methods 36: 207-224.
28. Yu C, Shan T, Feng A, Li Y, Zhu W, et al. (2011) Triptolide ameliorates Crohn's colitis is associated with inhibition of TLRs/NF-kappaB signaling pathway. Fitoterapia 82: 709-715.
29. Feng YH, Zhou WL, Wu QL, Li XY, Zhao WM, et al. (2002) Low dose of resveratrol enhanced immune response of mice. Acta Pharmacol Sin 23: 893-897.
30. Wu QL, Fu YF, Zhou WL, Wang JX, Feng YH, et al. (2005) Inhibition of S-adenosyl-L-homocysteine hydrolase induces immunosuppression. J Pharmacol Exp Ther 313: 705-711.
31. Bielawski J, Pierce JS, Snider J, Rembiesa B, Szulc ZM, et al. (2009) Comprehensive quantitative analysis of bioactive sphingolipids by high-performance liquid chromatography-tandem mass spectrometry. Methods Mol Biol 579: 443-467.
32. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ, (1951) Protein measurement with the Folin phenol reagent. J Biol Chem 193: 265-275.
33. Jia W (2009) Medical Metabonomics. Shanghai: Shanghai Scientific & Technical Publishers.
34. Joosten LA, Netea MG, Kim SH, Yoon DY, Oppers-Walgreen B, et al. (2006) IL-32, a proinflammatory cytokine in rheumatoid arthritis. Proc Natl Acad Sci U S A 103: 3298-3303.
35. Wang T, Fu F, Zhang L, Han B, Zhu M, et al. (2009) Effects of escin on acute inflammation and the immune system in mice. Pharmacol Rep 61: 697-704.
36. Zhou R, Zhang F, He PL, Zhou WL, Wu QL, et al. (2005) (5R)-5-hydroxytriptolide (LLDT-8), a novel triptolide analog mediates immunosuppressive effects in vitro and in vivo. Int Immunopharmacol 5: 1895-1903.
37. Kobayashi K, Kaneda K, Kasama T, (2001) Immunopathogenesis of delayed-type hypersensitivity. Microsc Res Tech 53: 241-245.
38. Piali L, Froidevaux S, Hess P, Nayler O, Bolli MH, et al. (2011) The selective sphingosine 1-phosphate receptor 1 agonist ponesimod protects against lymphocyte-mediated tissue inflammation. J Pharmacol Exp Ther 337: 547-556.
39. Merrill AH Jr, (2011) Sphingolipid and glycosphingolipid metabolic pathways in the era of sphingolipidomics. Chem Rev 111: 6387-6422.
40. Committee BC (2001) Guidance for Industry Bioanalytical Method Validation. In: Services USDoHaH, Administration FaD, Research CfDEa, Medicine CfV, editors.
41. Organization TWH (2009) Handbook: Good laboratory practice (2nd edition).
42. Lin L, Huang Z, Gao Y, Yan X, Xing J, et al. (2011) LC-MS based serum metabonomic analysis for renal cell carcinoma diagnosis, staging, and biomarker discovery. J Proteome Res 10: 1396-1405.
43. Ullrich SE, (1999) Dermal application of JP-8 jet fuel induces immune suppression. Toxicol Sci 52: 61-67.
44. Yang F, Zhuo L, Ananda S, Sun T, Li S, et al. (2011) Role of reactive oxygen species in triptolide-induced apoptosis of renal tubular cells and renal injury in rats. J Huazhong Univ Sci Technolog Med Sci 31: 335-341.
45. Wang Z, Jin H, Li C, Hou Y, Mei Q, et al. (2009) Heat shock protein 72 protects kidney proximal tubule cells from injury induced by triptolide by means of activation of the MEK/ERK pathway. Int J Toxicol 28: 177-189.
46. Ye X, Li W, Yan Y, Mao C, Cai R, et al. (2010) Effects of cytochrome P4503A inducer dexamethasone on the metabolism and toxicity of triptolide in rat. Toxicol Lett 192: 212-220.
47. Tao X, Fan F, Hoffmann V, Gao CY, Longo NS, et al. (2008) Effective therapy for nephritis in (NZB x NZW)F1 mice with triptolide and tripdiolide, the principal active components of the Chinese herbal remedy Tripterygium wilfordii Hook F. Arthritis Rheum. 58: 1774-1783.