Identification of functionally critical residues in the channel domain of inositol trisphosphate receptors

Journal of Biological Chemistry

Volumn 287, Issue 52, 2012, Pages 43674-43684

  Bhanumathy, Cunnigaiper ^a   Da Fonseca, Paula C A ^b   Morris, Edward P ^b   Joseph, Suresh K ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b INSTITUTE OF CANCER RESEARCH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID RESIDUES; CHANNEL FUNCTIONS; CHANNEL GATES; CHANNEL GATING; CHARGED RESIDUES; CYTOSOLIC; FUNCTIONAL ASSAYS; GST PULL-DOWN; HYDROPHOBIC AMINO ACIDS; ISOFORMS; N-TERMINALS; POSITIVELY CHARGED; R-STRUCTURES;

ALCOHOLS; CRYSTALLOGRAPHY; ELECTRON MICROSCOPY; SUGARS;

AMINO ACIDS;

ARGININE; CYSTEINE; HISTIDINE; INOSITOL 1,4,5 TRISPHOSPHATE RECEPTOR; ISOLEUCINE;

AMINO ACID COMPOSITION; AMINO TERMINAL SEQUENCE; ARTICLE; CHANNEL GATING; CRYSTALLOGRAPHY; ELECTRON MICROSCOPY; MUTAGENESIS; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN LOCALIZATION; RESIDUE ANALYSIS; STRUCTURE ACTIVITY RELATION;

AMINO ACID SUBSTITUTION; ANIMALS; CERCOPITHECUS AETHIOPS; COS CELLS; HEK293 CELLS; HUMANS; INOSITOL 1,4,5-TRISPHOSPHATE RECEPTORS; ION CHANNEL GATING; MODELS, MOLECULAR; MUTATION, MISSENSE; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RATS;

EID: 84871546315     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.415786     Document Type: Article

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