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Volumn 19, Issue 1, 2013, Pages 103-115

Cleavage and polyadenylation specificity factor 1 (CPSF1) regulates alternative splicing of interleukin 7 receptor (IL7R) exon 6

Author keywords

Alternative splicing; CPSF1; IL7R; Multiple sclerosis; Polyadenylation

Indexed keywords

CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR; CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR 1; INTERLEUKIN 7 RECEPTOR; MESSENGER RNA; UNCLASSIFIED DRUG;

EID: 84871458999     PISSN: 13558382     EISSN: 14699001     Source Type: Journal    
DOI: 10.1261/rna.035410.112     Document Type: Article
Times cited : (39)

References (60)
  • 1
    • 0031587826 scopus 로고    scopus 로고
    • Bcl-2 rescues T lymphopoiesis in interleukin-7 receptor-deficient mice
    • Akashi K, Kondo M, von Freeden-Jeffry U, Murray R, Weissman IL. 1997. Bcl-2 rescues T lymphopoiesis in interleukin-7 receptor-deficient mice. Cell 89: 1033-1041.
    • (1997) Cell , vol.89 , pp. 1033-1041
    • Akashi, K.1    Kondo, M.2    Von Freeden-Jeffry, U.3    Murray, R.4    Weissman, I.L.5
  • 4
    • 80052979140 scopus 로고    scopus 로고
    • Mechanisms and consequences of alternative polyadenylation
    • Campigli Di Giammartino D, Nishida K, Manley JL. 2011. Mechanisms and consequences of alternative polyadenylation. Mol Cell 43: 853-866.
    • (2011) Mol Cell , vol.43 , pp. 853-866
    • Campigli Di Giammartino, D.1    Nishida, K.2    Manley, J.L.3
  • 5
    • 0031948851 scopus 로고    scopus 로고
    • An intronic sequence element mediates both activation and repression of rat fibroblast growth factor receptor 2 pre-mRNA splicing
    • Carstens RP, McKeehan WL, Garcia-Blanco MA. 1998. An intronic sequence element mediates both activation and repression of rat fibroblast growth factor receptor 2 pre-mRNA splicing. Mol Cell Biol 18: 2205-2217.
    • (1998) Mol Cell Biol , vol.18 , pp. 2205-2217
    • Carstens, R.P.1    McKeehan, W.L.2    Garcia-Blanco, M.A.3
  • 7
    • 0033000782 scopus 로고    scopus 로고
    • Utilization of splicing elements and polyadenylation signal elements in the coupling of polyadenylation and last-intron removal
    • Cooke C, Hans H, Alwine JC. 1999. Utilization of splicing elements and polyadenylation signal elements in the coupling of polyadenylation and last-intron removal. Mol Cell Biol 19: 4971-4979.
    • (1999) Mol Cell Biol , vol.19 , pp. 4971-4979
    • Cooke, C.1    Hans, H.2    Alwine, J.C.3
  • 9
    • 77954491956 scopus 로고    scopus 로고
    • Soluble IL-7Ra (sCD127) inhibits IL-7 activity and is increased in HIV infection
    • Crawley AM, Faucher S, Angel JB. 2010. Soluble IL-7Ra (sCD127) inhibits IL-7 activity and is increased in HIV infection. J Immunol 184: 4679-4687.
    • (2010) J Immunol , vol.184 , pp. 4679-4687
    • Crawley, A.M.1    Faucher, S.2    Angel, J.B.3
  • 10
    • 38949111543 scopus 로고    scopus 로고
    • 3′ end mRNA processing: Molecular mechanisms and implications for health and disease
    • Danckwardt S, Hentze MW, Kulozik AE. 2008. 3′ end mRNA processing: molecular mechanisms and implications for health and disease. EMBO J 27: 482-498.
    • (2008) EMBO J , vol.27 , pp. 482-498
    • Danckwardt, S.1    Hentze, M.W.2    Kulozik, A.E.3
  • 11
    • 0021100690 scopus 로고
    • Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei
    • Dignam JD, Lebovitz RM, Roeder RG. 1983. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res 11: 1475-1489.
    • (1983) Nucleic Acids Res , vol.11 , pp. 1475-1489
    • Dignam, J.D.1    Lebovitz, R.M.2    Roeder, R.G.3
  • 12
    • 77957317868 scopus 로고    scopus 로고
    • Alternative splicing in multiple sclerosis and other autoimmune diseases
    • Evsyukova I, Somarelli JA, Gregory SG, Garcia-Blanco MA. 2010. Alternative splicing in multiple sclerosis and other autoimmune diseases. RNA Biol 7: 462-473.
    • (2010) RNA Biol , vol.7 , pp. 462-473
    • Evsyukova, I.1    Somarelli, J.A.2    Gregory, S.G.3    Garcia-Blanco, M.A.4
  • 15
    • 0035904279 scopus 로고    scopus 로고
    • Co-transcriptional splicing of pre-messenger RNAs: Considerations for the mechanism of alternative splicing
    • Goldstrohm AC, Greenleaf AL, Garcia-Blanco MA. 2001. Co-transcriptional splicing of pre-messenger RNAs: considerations for the mechanism of alternative splicing. Gene 277: 31-47.
    • (2001) Gene , vol.277 , pp. 31-47
    • Goldstrohm, A.C.1    Greenleaf, A.L.2    Garcia-Blanco, M.A.3
  • 16
  • 20
    • 34548299105 scopus 로고    scopus 로고
    • Risk alleles for multiple sclerosis identified by a genome-wide study
    • The International Multiple Sclerosis Genetics Consortium
    • The International Multiple Sclerosis Genetics Consortium. 2007. Risk alleles for multiple sclerosis identified by a genome-wide study. N Engl J Med 357: 851-862.
    • (2007) N Engl J Med , vol.357 , pp. 851-862
  • 23
    • 0842327458 scopus 로고    scopus 로고
    • Mutations in genes required for T-cell development: IL7R, CD45, IL2RG, JAK3, RAG1, RAG2, ARTEMIS, and ADA and severe combined immunodeficiency: HuGE review
    • Kalman L, Lindegren ML, Kobrynski L, Vogt R, Hannon H, Howard JT, Buckley R. 2004. Mutations in genes required for T-cell development: IL7R, CD45, IL2RG, JAK3, RAG1, RAG2, ARTEMIS, and ADA and severe combined immunodeficiency: HuGE review. Genet Med 6: 16-26.
    • (2004) Genet Med , vol.6 , pp. 16-26
    • Kalman, L.1    Lindegren, M.L.2    Kobrynski, L.3    Vogt, R.4    Hannon, H.5    Howard, J.T.6    Buckley, R.7
  • 24
    • 0026041206 scopus 로고
    • Cleavage and polyadenylation factor CPF specifically interacts with the premRNA 3′ processing signal AAUAAA
    • Keller W, Bienroth S, Lang KM, Christofori G. 1991. Cleavage and polyadenylation factor CPF specifically interacts with the premRNA 3′ processing signal AAUAAA. EMBO J 10: 4241-4249.
    • (1991) EMBO J , vol.10 , pp. 4241-4249
    • Keller, W.1    Bienroth, S.2    Lang, K.M.3    Christofori, G.4
  • 26
    • 0033667593 scopus 로고    scopus 로고
    • Expression analysis and characterization of alternatively spliced transcripts of human IL-7Ra chain encoding two truncated receptor proteins in relapsed childhood ALL
    • Korte A, Köchling J, Badiali L, Eckert C, Andreae J, Geilen W, Kebelmann-Betzing C, Taube T, Wu S, Henze G, et al. 2000. Expression analysis and characterization of alternatively spliced transcripts of human IL-7Ra chain encoding two truncated receptor proteins in relapsed childhood ALL. Cytokine 12: 1597-1608.
    • (2000) Cytokine , vol.12 , pp. 1597-1608
    • Korte, A.1    Köchling, J.2    Badiali, L.3    Eckert, C.4    Andreae, J.5    Geilen, W.6    Kebelmann-Betzing, C.7    Taube, T.8    Wu, S.9    Henze, G.10
  • 27
    • 33745944934 scopus 로고    scopus 로고
    • Direct interactions between subunits of CPSF and the U2 snRNP contribute to the coupling of pre-mRNA 3′ end processing and splicing
    • Kyburz A, Friedlein A, Langen H, Keller W. 2006. Direct interactions between subunits of CPSF and the U2 snRNP contribute to the coupling of pre-mRNA 3′ end processing and splicing. Mol Cell 23: 195-205.
    • (2006) Mol Cell , vol.23 , pp. 195-205
    • Kyburz, A.1    Friedlein, A.2    Langen, H.3    Keller, W.4
  • 28
    • 0034743629 scopus 로고    scopus 로고
    • The 3′-end-processing factor CPSF is required for the splicing of single-intron pre-mRNAs in vivo
    • Li Y, Chen Z-Y, Wang W, Baker CC, Krug RM. 2001. The 3′-end- processing factor CPSF is required for the splicing of single-intron pre-mRNAs in vivo. RNA 7: 920-931.
    • (2001) RNA , vol.7 , pp. 920-931
    • Li, Y.1    Chen, Z.-Y.2    Wang, W.3    Baker, C.C.4    Krug, R.M.5
  • 29
    • 0031840978 scopus 로고    scopus 로고
    • Regulation of alternative polyadenylation by U1 snRNPs and SRp20
    • Lou H, Neugebauer KM, Gagel RF, Berget SM. 1998. Regulation of alternative polyadenylation by U1 snRNPs and SRp20. Mol Cell Biol 18: 4977-4985.
    • (1998) Mol Cell Biol , vol.18 , pp. 4977-4985
    • Lou, H.1    Neugebauer, K.M.2    Gagel, R.F.3    Berget, S.M.4
  • 31
    • 58149144383 scopus 로고    scopus 로고
    • Alternative polyadenylation: A twist on mRNA 3′ end formation
    • Lutz CS. 2008. Alternative polyadenylation: a twist on mRNA 3′ end formation. ACS Chem Biol 3: 609-617.
    • (2008) ACS Chem Biol , vol.3 , pp. 609-617
    • Lutz, C.S.1
  • 32
    • 84857772692 scopus 로고    scopus 로고
    • Alternative mRNA polyadenylation in eukaryotes: An effective regulator of gene expression
    • Lutz CS, Moreira A. 2011. Alternative mRNA polyadenylation in eukaryotes: an effective regulator of gene expression. Wiley Interdiscip Rev RNA 2: 23-31.
    • (2011) Wiley Interdiscip Rev RNA , vol.2 , pp. 23-31
    • Lutz, C.S.1    Moreira, A.2
  • 33
    • 0030024350 scopus 로고    scopus 로고
    • Interaction between the U1 snRNP-A and the 160-kD subunit of cleavage-polyadenylation specificity factor increases polyadenylation efficiency in vitro
    • Lutz CS, Murthy KGK, Schek N, O'Connor JP, Manley JL, Alwine JC. 1996. Interaction between the U1 snRNP-A and the 160-kD subunit of cleavage-polyadenylation specificity factor increases polyadenylation efficiency in vitro. Genes Dev 10: 325-337.
    • (1996) Genes Dev , vol.10 , pp. 325-337
    • Lutz, C.S.1    Murthy, K.G.K.2    Schek, N.3    O'Connor, J.P.4    Manley, J.L.5    Alwine, J.C.6
  • 34
    • 10244239317 scopus 로고    scopus 로고
    • Consequences of regulated pre-mRNA splicing in the immune system
    • Lynch KW. 2004. Consequences of regulated pre-mRNA splicing in the immune system. Nat Rev Immunol 4: 931-940.
    • (2004) Nat Rev Immunol , vol.4 , pp. 931-940
    • Lynch, K.W.1
  • 35
    • 0030442579 scopus 로고    scopus 로고
    • The V-J recombination of T cell receptor-g genes is blocked in interleukin-7 receptor-deficient mice
    • Maki K, Sunaga S, Ikuta K. 1996. The V-J recombination of T cell receptor-g genes is blocked in interleukin-7 receptor-deficient mice. J Exp Med 184: 2423-2427.
    • (1996) J Exp Med , vol.184 , pp. 2423-2427
    • Maki, K.1    Sunaga, S.2    Ikuta, K.3
  • 36
    • 33846632842 scopus 로고    scopus 로고
    • Interleukin-7 receptor expression: Intelligent design
    • Mazzucchelli R, Durum SK. 2007. Interleukin-7 receptor expression: intelligent design. Nat Rev Immunol 7: 144-154.
    • (2007) Nat Rev Immunol , vol.7 , pp. 144-154
    • Mazzucchelli, R.1    Durum, S.K.2
  • 38
    • 0036747331 scopus 로고    scopus 로고
    • A novel function for the U2AF 65 splicing factor in promoting pre-mRNA 3′-end processing
    • Millevoi S, Geraghty F, Idowu B, Tam JL, Antoniou M, Vagner S. 2002. A novel function for the U2AF 65 splicing factor in promoting pre-mRNA 3′-end processing. EMBO Rep 3: 869-874.
    • (2002) EMBO Rep , vol.3 , pp. 869-874
    • Millevoi, S.1    Geraghty, F.2    Idowu, B.3    Tam, J.L.4    Antoniou, M.5    Vagner, S.6
  • 39
    • 33750200773 scopus 로고    scopus 로고
    • An interaction between U2AF 65 and CF I(m) links the splicing and 3′ processing machineries
    • Millevoi S, Loulergue C, Dettwiler S, Karaa SZ, Keller W, Antoniou M, Vagner S. 2006. An interaction between U2AF 65 and CF I(m) links the splicing and 3′ processing machineries. EMBO J 25: 4854-4864.
    • (2006) EMBO J , vol.25 , pp. 4854-4864
    • Millevoi, S.1    Loulergue, C.2    Dettwiler, S.3    Karaa, S.Z.4    Keller, W.5    Antoniou, M.6    Vagner, S.7
  • 40
    • 0028789410 scopus 로고
    • The 160-kD subunit of human cleavage-polyadenylation specificity factor coordinates pre-mRNA 3′-end formation
    • Murthy KG, Manley JL. 1995. The 160-kD subunit of human cleavage-polyadenylation specificity factor coordinates pre-mRNA 3′-end formation. Genes Dev 9: 2672-2683.
    • (1995) Genes Dev , vol.9 , pp. 2672-2683
    • Murthy, K.G.1    Manley, J.L.2
  • 41
    • 0025935848 scopus 로고
    • Mutation of the AAUAAA polyadenylation signal depresses in vitro splicing of proximal but not distal introns
    • Niwa M, Berget SM. 1991. Mutation of the AAUAAA polyadenylation signal depresses in vitro splicing of proximal but not distal introns. Genes Dev 5: 2086-2095.
    • (1991) Genes Dev , vol.5 , pp. 2086-2095
    • Niwa, M.1    Berget, S.M.2
  • 42
    • 4143085811 scopus 로고    scopus 로고
    • Suppression of IL7Ra transcription by IL-7 and other prosurvival cytokines: A novel mechanism for maximizing IL-7-dependent T cell survival
    • Park JH, Yu Q, Erman B, Appelbaum JS, Montoya-Durango D, Grimes HL, Singer A. 2004. Suppression of IL7Ra transcription by IL-7 and other prosurvival cytokines: a novel mechanism for maximizing IL-7-dependent T cell survival. Immunity 21: 289-302.
    • (2004) Immunity , vol.21 , pp. 289-302
    • Park, J.H.1    Yu, Q.2    Erman, B.3    Appelbaum, J.S.4    Montoya-Durango, D.5    Grimes, H.L.6    Singer, A.7
  • 44
    • 0025829407 scopus 로고
    • Organization of the murine and human interleukin-7 receptor genes: Two mRNAs generated by differential splicing and presence of a type I-interferon-inducible promoter
    • Pleiman CM, Gimpel SD, Park LS, Harada H, Taniguchi T, Ziegler SF. 1991. Organization of the murine and human interleukin-7 receptor genes: two mRNAs generated by differential splicing and presence of a type I-interferon-inducible promoter. Mol Cell Biol 11: 3052-3059.
    • (1991) Mol Cell Biol , vol.11 , pp. 3052-3059
    • Pleiman, C.M.1    Gimpel, S.D.2    Park, L.S.3    Harada, H.4    Taniguchi, T.5    Ziegler, S.F.6
  • 45
    • 80052447253 scopus 로고    scopus 로고
    • Ending the message: Poly(A) signals then and now
    • Proudfoot NJ. 2011. Ending the message: poly(A) signals then and now. Genes Dev 25: 1770-1782.
    • (2011) Genes Dev , vol.25 , pp. 1770-1782
    • Proudfoot, N.J.1
  • 47
    • 67649158212 scopus 로고    scopus 로고
    • Identification and biochemical characterization of human plasma soluble IL-7R: Lower concentrations in HIV-1-infected patients
    • Rose T, Lambotte O, Pallier C, Delfraissy J-F, Colle J-H. 2009. Identification and biochemical characterization of human plasma soluble IL-7R: lower concentrations in HIV-1-infected patients. J Immunol 182: 7389-7397.
    • (2009) J Immunol , vol.182 , pp. 7389-7397
    • Rose, T.1    Lambotte, O.2    Pallier, C.3    Delfraissy, J.-F.4    Colle, J.-H.5
  • 48
    • 46249092601 scopus 로고    scopus 로고
    • Proliferating cells express mRNAs with shortened 3′ untranslated regions and fewer microRNA target sites
    • Sandberg R, Neilson JR, Sarma A, Sharp PA, Burge CB. 2008. Proliferating cells express mRNAs with shortened 3′ untranslated regions and fewer microRNA target sites. Science 320: 1643-1647.
    • (2008) Science , vol.320 , pp. 1643-1647
    • Sandberg, R.1    Neilson, J.R.2    Sarma, A.3    Sharp, P.A.4    Burge, C.B.5
  • 49
    • 73649139638 scopus 로고    scopus 로고
    • Global changes in processing of mRNA 3′ untranslated regions characterize clinically distinct cancer subtypes
    • Singh P, Alley TL, Wright SM, Kamdar S, Schott W, Wilpan RY, Mills KD, Graber JH. 2009. Global changes in processing of mRNA 3′ untranslated regions characterize clinically distinct cancer subtypes. Cancer Res 69: 9422-9430.
    • (2009) Cancer Res , vol.69 , pp. 9422-9430
    • Singh, P.1    Alley, T.L.2    Wright, S.M.3    Kamdar, S.4    Schott, W.5    Wilpan, R.Y.6    Mills, K.D.7    Graber, J.H.8
  • 50
    • 0032246188 scopus 로고    scopus 로고
    • Levels of polyadenylation factor CstF-64 control IgM heavy chain mRNA accumulation and other events associated with B cell differentiation
    • Takagaki Y, Manley JL. 1998. Levels of polyadenylation factor CstF-64 control IgM heavy chain mRNA accumulation and other events associated with B cell differentiation. Mol Cell 2: 761-771.
    • (1998) Mol Cell , vol.2 , pp. 761-771
    • Takagaki, Y.1    Manley, J.L.2
  • 51
    • 0030606286 scopus 로고    scopus 로고
    • The polyadenylation factor CstF-64 regulates alternative processing of IgM heavy chain pre-mRNA during B cell differentiation
    • Takagaki Y, Seipelt RL, Peterson ML, Manley JL. 1996. The polyadenylation factor CstF-64 regulates alternative processing of IgM heavy chain pre-mRNA during B cell differentiation. Cell 87: 941-952.
    • (1996) Cell , vol.87 , pp. 941-952
    • Takagaki, Y.1    Seipelt, R.L.2    Peterson, M.L.3    Manley, J.L.4
  • 52
    • 33846870354 scopus 로고    scopus 로고
    • Widespread mRNA polyadenylation events in introns indicate dynamic interplay between polyadenylation and splicing
    • Tian B, Pan Z, Lee JY. 2007. Widespread mRNA polyadenylation events in introns indicate dynamic interplay between polyadenylation and splicing. Genome Res 17: 156-165.
    • (2007) Genome Res , vol.17 , pp. 156-165
    • Tian, B.1    Pan, Z.2    Lee, J.Y.3
  • 53
    • 48249139449 scopus 로고    scopus 로고
    • Multiple sclerosis: An immune or neurodegenerative disorder?
    • Trapp BD, Nave K-A. 2008. Multiple sclerosis: an immune or neurodegenerative disorder? Annu Rev Neurosci 31: 247-269.
    • (2008) Annu Rev Neurosci , vol.31 , pp. 247-269
    • Trapp, B.D.1    Nave, K.-A.2
  • 54
    • 0034008058 scopus 로고    scopus 로고
    • The carboxyl terminus of vertebrate poly(A) polymerase interacts with U2AF 65 to couple 3′-end processing and splicing
    • Vagner S, Vagner C, Mattaj IW. 2000. The carboxyl terminus of vertebrate poly(A) polymerase interacts with U2AF 65 to couple 3′-end processing and splicing. Genes Dev 14: 403-413.
    • (2000) Genes Dev , vol.14 , pp. 403-413
    • Vagner, S.1    Vagner, C.2    Mattaj, I.W.3
  • 56
    • 34548758543 scopus 로고    scopus 로고
    • Splicing in disease: Disruption of the splicing code and the decoding machinery
    • Wang G-S, Cooper TA. 2007. Splicing in disease: disruption of the splicing code and the decoding machinery. Nat Rev Genet 8: 749-761.
    • (2007) Nat Rev Genet , vol.8 , pp. 749-761
    • Wang, G.-S.1    Cooper, T.A.2
  • 57
    • 81255210913 scopus 로고    scopus 로고
    • Quantitative mass spectrometry of DENV-2 RNA-interacting proteins reveals that the DEAD-box RNA helicase DDX6 binds the DB1 and DB2 3′ UTR structures
    • Ward AM, Bidet K, Yinglin A, Ler SG, Hogue K, Blackstock W, Gunaratne J, Garcia-Blanco MA. 2011. Quantitative mass spectrometry of DENV-2 RNA-interacting proteins reveals that the DEAD-box RNA helicase DDX6 binds the DB1 and DB2 3′ UTR structures. RNA Biol 8: 1173-1186.
    • (2011) RNA Biol , vol.8 , pp. 1173-1186
    • Ward, A.M.1    Bidet, K.2    Yinglin, A.3    Ler, S.G.4    Hogue, K.5    Blackstock, W.6    Gunaratne, J.7    Garcia-Blanco, M.A.8


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