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Volumn 35, Issue 1, 2013, Pages 86-93

Effects of epidermal growth factor receptor and insulin-like growth factor 1 receptor inhibition on proliferation and intracellular signaling in cutaneous SCCHN: Potential for dual inhibition as a therapeutic modality

Author keywords

cutaneous squamous cell carcinoma; epidermal growth factor receptor; insulin like growth factor receptor

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; ERLOTINIB; MITOGEN ACTIVATED PROTEIN KINASE; PICROPODOPHYLLIN; PODOPHYLLIN; PROTEIN KINASE B; PROTEIN P42; PROTEIN P44; SOMATOMEDIN C RECEPTOR; UNCLASSIFIED DRUG;

EID: 84871320854     PISSN: 10433074     EISSN: 10970347     Source Type: Journal    
DOI: 10.1002/hed.22936     Document Type: Article
Times cited : (13)

References (43)
  • 1
    • 0035967241 scopus 로고    scopus 로고
    • Cutaneous squamous-cell carcinoma
    • DOI 10.1056/NEJM200103293441306
    • Alam M, Ratner D,. Cutaneous squamous-cell carcinoma. N Engl J Med 2001; 344: 975-983. (Pubitemid 32240317)
    • (2001) New England Journal of Medicine , vol.344 , Issue.13 , pp. 975-983
    • Alam, M.1    Ratner, D.2
  • 2
    • 0026773479 scopus 로고
    • Prognostic factors for local recurrence, metastasis, and survival rates in squamous cell carcinoma of the skin, ear, and lip. Implications for treatment modality selection
    • Rowe DE, Carroll RJ, Day CL Jr,. Prognostic factors for local recurrence, metastasis, and survival rates in squamous cell carcinoma of the skin, ear, and lip. Implications for treatment modality selection. J Am Acad Dermatol 1992; 26: 976-990.
    • (1992) J Am Acad Dermatol , vol.26 , pp. 976-990
    • Rowe, D.E.1    Carroll, R.J.2    Day, Jr.C.L.3
  • 3
    • 0033494682 scopus 로고    scopus 로고
    • Preoperative treatment of advanced skin carcinoma with cisplatin and bleomycin
    • DOI 10.1097/00000421-199902000-00008
    • Denic S,. Preoperative treatment of advanced skin carcinoma with cisplatin and bleomycin. Am J Clin Oncol 1999; 22: 32-34. (Pubitemid 30261586)
    • (1999) American Journal of Clinical Oncology: Cancer Clinical Trials , vol.22 , Issue.1 , pp. 32-34
    • Denic, S.1
  • 4
    • 0026727926 scopus 로고
    • Salvage cisplatin and adriamycin for advanced or recurrent basal or squamous cell carcinoma of the face
    • Merimsky O, Neudorfer M, Spitzer E, et al. Salvage cisplatin and adriamycin for advanced or recurrent basal or squamous cell carcinoma of the face. Anticancer Drugs 1992; 3: 481-484.
    • (1992) Anticancer Drugs , vol.3 , pp. 481-484
    • Merimsky, O.1    Neudorfer, M.2    Spitzer, E.3
  • 5
    • 67849124741 scopus 로고    scopus 로고
    • Metastatic cutaneous squamous cell carcinoma to the parotid and cervical lymph nodes: Treatment and outcomes
    • Bumpous J,. Metastatic cutaneous squamous cell carcinoma to the parotid and cervical lymph nodes: treatment and outcomes. Curr Opin Otolaryngol Head Neck Surg 2009; 17: 122-125.
    • (2009) Curr Opin Otolaryngol Head Neck Surg , vol.17 , pp. 122-125
    • Bumpous, J.1
  • 6
    • 17444410011 scopus 로고    scopus 로고
    • Immunohistochemical analysis of EGFR and HER-2 in patients with metastatic squamous cell carcinoma of the skin
    • Maubec E, Duvillard P, Velasco V, et al. Immunohistochemical analysis of EGFR and HER-2 in patients with metastatic squamous cell carcinoma of the skin. Anticancer Res 2005; 25: 1205-1210. (Pubitemid 40546791)
    • (2005) Anticancer Research , vol.25 , Issue.B2 , pp. 1205-1210
    • Maubec, E.1    Duvillard, P.2    Velasco, V.3    Crickx, B.4    Avril, M.-F.5
  • 7
    • 0034980383 scopus 로고    scopus 로고
    • Epidermal growth factor receptor overexpression and genetic aberrations in metastatic squamous-cell carcinoma of the skin
    • DOI 10.1159/000051637
    • Shimizu T, Izumi H, Oga A, et al. Epidermal growth factor receptor overexpression and genetic aberrations in metastatic squamous-cell carcinoma of the skin. Dermatology 2001; 202: 203-206. (Pubitemid 32506966)
    • (2001) Dermatology , vol.202 , Issue.3 , pp. 203-206
    • Shimizu, T.1    Izumi, H.2    Oga, A.3    Furumoto, H.4    Murakami, T.5    Ofuji, R.6    Muto, M.7    Sasaki, K.8
  • 8
    • 1942538505 scopus 로고    scopus 로고
    • Epidermal Growth Factor Receptor-Mediated Activation of Stat3 during Multistage Skin Carcinogenesis
    • DOI 10.1158/0008-5472.CAN-03-3197
    • Chan KS, Carbajal S, Kiguchi K, et al. Epidermal growth factor receptor-mediated activation of Stat3 during multistage skin carcinogenesis. Cancer Res 2004; 64: 2382-2389. (Pubitemid 38523890)
    • (2004) Cancer Research , vol.64 , Issue.7 , pp. 2382-2389
    • Chan, K.S.1    Carbajal, S.2    Kiguchi, K.3    Clifford, J.4    Sano, S.5    DiGiovanni, J.6
  • 9
    • 0031409362 scopus 로고    scopus 로고
    • Epidermal growth factor receptor inhibition by a monoclonal antibody as anticancer therapy
    • Mendelsohn J,. Epidermal growth factor receptor inhibition by a monoclonal antibody as anticancer therapy. Clin Cancer Res 1997; 3: 2703-2707. (Pubitemid 28133130)
    • (1997) Clinical Cancer Research , vol.3 , Issue.II12 , pp. 2703-2707
    • Mendelsohn, J.1
  • 12
    • 36048974574 scopus 로고    scopus 로고
    • Primary and acquired resistance to anti-EGFR targeted drugs in cancer therapy
    • DOI 10.1111/j.1432-0436.2007.00200.x
    • Morgillo F, Bareschino MA, Bianco R, et al. Primary and acquired resistance to anti-EGFR targeted drugs in cancer therapy. Differentiation 2007; 75: 788-799. (Pubitemid 350086168)
    • (2007) Differentiation , vol.75 , Issue.9 , pp. 788-799
    • Morgillo, F.1    Bareschino, M.A.2    Bianco, R.3    Tortora, G.4    Ciardiello, F.5
  • 13
    • 34547107855 scopus 로고    scopus 로고
    • Insulin-like growth factor receptor as a therapeutic target in head and neck cancer
    • DOI 10.1158/1078-0432.CCR-06-2040
    • Barnes CJ, Ohshiro K, Rayala SK, et al. Insulin-like growth factor receptor as a therapeutic target in head and neck cancer. Clin Cancer Res 2007; 13: 4291-4299. (Pubitemid 47105993)
    • (2007) Clinical Cancer Research , vol.13 , Issue.14 , pp. 4291-4299
    • Barnes, C.J.1    Ohshiro, K.2    Rayala, S.K.3    El-Naggar, A.K.4    Kumar, R.5
  • 14
    • 77953078857 scopus 로고    scopus 로고
    • Combined inhibition of IGFR enhances the effects of gefitinib in H1650: A lung cancer cell line with EGFR mutation and primary resistance to EGFR-TK inhibitors
    • Choi YJ, Rho JK, Jeon BS, et al. Combined inhibition of IGFR enhances the effects of gefitinib in H1650: a lung cancer cell line with EGFR mutation and primary resistance to EGFR-TK inhibitors. Cancer Chemother Pharmacol 2010; 66: 381-388.
    • (2010) Cancer Chemother Pharmacol , vol.66 , pp. 381-388
    • Choi, Y.J.1    Rho, J.K.2    Jeon, B.S.3
  • 16
    • 33750571170 scopus 로고    scopus 로고
    • Heterodimerization of insulin-like growth factor receptor/epidermal growth factor receptor and induction of survivin expression counteract the antitumor action of erlotinib
    • DOI 10.1158/0008-5472.CAN-06-1684
    • Morgillo F, Woo JK, Kim ES, et al. Heterodimerization of insulin-like growth factor receptor/epidermal growth factor receptor and induction of survivin expression counteract the antitumor action of erlotinib. Cancer Res 2006; 66: 10100-10111. (Pubitemid 44672064)
    • (2006) Cancer Research , vol.66 , Issue.20 , pp. 10100-10111
    • Morgillo, F.1    Woo, J.K.2    Kim, E.S.3    Hong, W.K.4    Lee, H.-Y.5
  • 17
    • 78751487508 scopus 로고    scopus 로고
    • Dual inhibition of epidermal growth factor receptor and insulin-like growth factor receptor I: Reduction of angiogenesis and tumor growth in cutaneous squamous cell carcinoma
    • Galer CE, Corey CL, Wang Z, et al. Dual inhibition of epidermal growth factor receptor and insulin-like growth factor receptor I: reduction of angiogenesis and tumor growth in cutaneous squamous cell carcinoma. Head Neck 2011; 33: 189-198.
    • (2011) Head Neck , vol.33 , pp. 189-198
    • Galer, C.E.1    Corey, C.L.2    Wang, Z.3
  • 19
    • 1642494838 scopus 로고    scopus 로고
    • Cyclolignans as Inhibitors of the Insulin-Like Growth Factor-1 Receptor and Malignant Cell Growth
    • DOI 10.1158/0008-5472.CAN-03-2522
    • Girnita A, Girnita L, del Prete F, et al. Cyclolignans as inhibitors of the insulin-like growth factor-1 receptor and malignant cell growth. Cancer Res 2004; 64: 236-242. (Pubitemid 38114104)
    • (2004) Cancer Research , vol.64 , Issue.1 , pp. 236-242
    • Girnita, A.1    Girnita, L.2    Del Prete, F.3    Bartolazzi, A.4    Larsson, O.5    Axelson, M.6
  • 20
    • 47249143238 scopus 로고    scopus 로고
    • Oral picropodophyllin (PPP) is well tolerated in vivo and inhibits IGF-1R expression and growth of uveal melanoma
    • Economou MA, Andersson S, Vasilcanu D, et al. Oral picropodophyllin (PPP) is well tolerated in vivo and inhibits IGF-1R expression and growth of uveal melanoma. Invest Ophthalmol Vis Sci 2008; 49: 2337-2342.
    • (2008) Invest Ophthalmol Vis Sci , vol.49 , pp. 2337-2342
    • Economou, M.A.1    Andersson, S.2    Vasilcanu, D.3
  • 21
    • 56849130445 scopus 로고    scopus 로고
    • The insulin-like growth factor-I receptor inhibitor picropodophyllin causes tumor regression and attenuates mechanisms involved in invasion of uveal melanoma cells
    • . 86 Thesis 4
    • Girnita A, All-Ericsson C, Economou MA, et al. The insulin-like growth factor-I receptor inhibitor picropodophyllin causes tumor regression and attenuates mechanisms involved in invasion of uveal melanoma cells. Acta Ophthalmol 2008; 86 Thesis 4: 26-34.
    • (2008) Acta Ophthalmol , pp. 26-34
    • Girnita, A.1    All-Ericsson, C.2    Economou, M.A.3
  • 22
    • 68849090494 scopus 로고    scopus 로고
    • Insulin-like growth factor-I receptor tyrosine kinase inhibitor cyclolignan picropodophyllin inhibits proliferation and induces apoptosis in multidrug resistant osteosarcoma cell lines
    • Duan Z, Choy E, Harmon D, et al. Insulin-like growth factor-I receptor tyrosine kinase inhibitor cyclolignan picropodophyllin inhibits proliferation and induces apoptosis in multidrug resistant osteosarcoma cell lines. Mol Cancer Ther 2009; 8: 2122-2130.
    • (2009) Mol Cancer Ther , vol.8 , pp. 2122-2130
    • Duan, Z.1    Choy, E.2    Harmon, D.3
  • 23
    • 75749094341 scopus 로고    scopus 로고
    • Targeting the insulin-like growth factor-1 receptor by picropodophyllin as a treatment option for glioblastoma
    • Yin S, Girnita A, Stromberg T, et al. Targeting the insulin-like growth factor-1 receptor by picropodophyllin as a treatment option for glioblastoma. Neuro Oncol 2010; 12: 19-27.
    • (2010) Neuro Oncol , vol.12 , pp. 19-27
    • Yin, S.1    Girnita, A.2    Stromberg, T.3
  • 24
    • 0019471387 scopus 로고
    • Tumorigenic keratinocyte lines requiring anchorage and fibroblast support cultured from human squamous cell carcinomas
    • Rheinwald JG, Beckett MA,. Tumorigenic keratinocyte lines requiring anchorage and fibroblast support cultures from human squamous cell carcinomas. Cancer Res 1981; 41: 1657-1663. (Pubitemid 11114553)
    • (1981) Cancer Research , vol.41 , Issue.5 , pp. 1657-1663
    • Rheinwald, J.G.1    Beckett, M.A.2
  • 25
    • 0034030578 scopus 로고    scopus 로고
    • Spontaneous keratinocyte cell lines representing early and advanced stages of malignant transformation of the epidermis
    • DOI 10.1034/j.1600-0625.2000.009002104.x
    • Proby CM, Purdie KJ, Sexton CJ, et al. Spontaneous keratinocyte cell lines representing early and advanced stages of malignant transformation of the epidermis. Exp Dermatol 2000; 9: 104-117. (Pubitemid 30192708)
    • (2000) Experimental Dermatology , vol.9 , Issue.2 , pp. 104-117
    • Proby, C.M.1    Purdie, K.J.2    Sexton, C.J.3    Purkis, P.4    Navsaria, H.A.5    Stables, J.N.6    Leigh, I.M.7
  • 26
    • 56849088872 scopus 로고    scopus 로고
    • Inhibition of VEGF secretion and experimental choroidal neovascularization by picropodophyllin (PPP), an inhibitor of the insulin-like growth factor-1 receptor
    • . 86 Thesis 4
    • Economou MA, Wu J, Vasilcanu D, et al. Inhibition of VEGF secretion and experimental choroidal neovascularization by picropodophyllin (PPP), an inhibitor of the insulin-like growth factor-1 receptor. Acta Ophthalmol 2008; 86 Thesis 4: 42-49.
    • (2008) Acta Ophthalmol , pp. 42-49
    • Economou, M.A.1    Wu, J.2    Vasilcanu, D.3
  • 28
    • 78649689208 scopus 로고    scopus 로고
    • Characterization of the intestinal cancer stem cell marker CD166 in the human and mouse gastrointestinal tract
    • Levin TG, Powell AE, Davies PS, et al. Characterization of the intestinal cancer stem cell marker CD166 in the human and mouse gastrointestinal tract. Gastroenterology 2010; 139: 2072-2082.
    • (2010) Gastroenterology , vol.139 , pp. 2072-2082
    • Levin, T.G.1    Powell, A.E.2    Davies, P.S.3
  • 29
    • 33845792555 scopus 로고    scopus 로고
    • CellProfiler: Image analysis software for identifying and quantifying cell phenotypes
    • Carpenter AE, Jones TR, Lamprecht MR, et al. CellProfiler: image analysis software for identifying and quantifying cell phenotypes. Genome Biol 2006; 7: R100.
    • (2006) Genome Biol , vol.7
    • Carpenter, A.E.1    Jones, T.R.2    Lamprecht, M.R.3
  • 30
    • 0036805042 scopus 로고    scopus 로고
    • Expression of epidermal growth factor receptor and related phosphorylation proteins in hypertrophic scars and normal skin
    • Cheng B, Fu X, Sun T, et al. Expression of epidermal growth factor receptor and related phosphorylation proteins in hypertrophic scars and normal skin. Chin Med J (Engl) 2002; 115: 1525-1528. (Pubitemid 35282916)
    • (2002) Chinese Medical Journal , vol.115 , Issue.10 , pp. 1525-1528
    • Cheng, B.1    Fu, X.2    Sun, T.3    Sun, X.4    Sheng, Z.5
  • 31
    • 79959238154 scopus 로고    scopus 로고
    • Outcome of patients treated surgically for lymph node metastases from cutaneous squamous cell carcinoma of the head and neck
    • Givi B, Andersen PE, Diggs BS, Wax MK, Gross ND,. Outcome of patients treated surgically for lymph node metastases from cutaneous squamous cell carcinoma of the head and neck. Head Neck 201133: 999-1004.
    • (2011) Head Neck , vol.133 , pp. 999-1004
    • Givi, B.1    Andersen, P.E.2    Diggs, B.S.3    Wax, M.K.4    Gross, N.D.5
  • 32
    • 57649108802 scopus 로고    scopus 로고
    • Combination of an EGFR blocker and a COX-2 inhibitor for the treatment of advanced cutaneous squamous cell carcinoma
    • Jalili A, Pinc A, Pieczkowski F, et al. Combination of an EGFR blocker and a COX-2 inhibitor for the treatment of advanced cutaneous squamous cell carcinoma. J Dtsch Dermatol Ges 2008; 6: 1066-1069.
    • (2008) J Dtsch Dermatol Ges , vol.6 , pp. 1066-1069
    • Jalili, A.1    Pinc, A.2    Pieczkowski, F.3
  • 33
    • 27944477029 scopus 로고    scopus 로고
    • Inhibition of insulin-like growth factor-1 receptor signaling enhances growth-inhibitory and proapoptotic effects of gefitinib (Iressa) in human breast cancer cells
    • Camirand A, Zakikhani M, Young F, et al. Inhibition of insulin-like growth factor-1 receptor signaling enhances growth-inhibitory and proapoptotic effects of gefitinib (Iressa) in human breast cancer cells. Breast Cancer Res 2005; 7: R570-R579.
    • (2005) Breast Cancer Res , vol.7
    • Camirand, A.1    Zakikhani, M.2    Young, F.3
  • 34
    • 10344247119 scopus 로고    scopus 로고
    • A recombinant humanized anti-insulin-like growth factor-receptor type I antibody (h7C10) enhances the antitumor activity of vinorelbine and anti-epidermal growth factor receptor therapy against human cancer xenografts
    • DOI 10.1002/ijc.20543
    • Goetsch L, Gonzalez A, Leger O, et al. A recombinant humanized anti-insulin-like growth factor receptor type I antibody (h7C10) enhances the antitumor activity of vinorelbine and anti-epidermal growth factor receptor therapy against human cancer xenografts. Int J Cancer 2005; 113: 316-328. (Pubitemid 39628325)
    • (2005) International Journal of Cancer , vol.113 , Issue.2 , pp. 316-328
    • Goetsch, L.1    Gonzalez, A.2    Leger, O.3    Beck, A.4    Pauwels, P.J.5    Haeuw, J.F.6    Corvaia, N.7
  • 37
    • 33645652766 scopus 로고    scopus 로고
    • The MEK/MAPK pathway is involved in the resistance of breast cancer cells to the EGFR tyrosine kinase inhibitor gefitinib
    • Normanno N, De Luca A, Maiello MR, et al. The MEK/MAPK pathway is involved in the resistance of breast cancer cells to the EGFR tyrosine kinase inhibitor gefitinib. J Cell Physiol 2006; 207: 420-427.
    • (2006) J Cell Physiol , vol.207 , pp. 420-427
    • Normanno, N.1    De Luca, A.2    Maiello, M.R.3
  • 38
    • 2642570481 scopus 로고    scopus 로고
    • Sensitivity to gefitinib (Iressa, ZD1839) in non-small cell lung cancer cell lines correlates with dependence on the epidermal growth factor (EGF) receptor/extracellular signal-regulated kinase 1/2 and EGF receptor/Akt pathway for proliferation
    • Ono M, Hirata A, Kometani T, et al. Sensitivity to gefitinib (Iressa, ZD1839) in non-small cell lung cancer cell lines correlates with dependence on the epidermal growth factor (EGF) receptor/extracellular signal-regulated kinase 1/2 and EGF receptor/Akt pathway for proliferation. Mol Cancer Ther 2004; 3: 465-472. (Pubitemid 39193724)
    • (2004) Molecular Cancer Therapeutics , vol.3 , Issue.4 , pp. 465-472
    • Ono, M.1    Hirata, A.2    Kometani, T.3    Miyagawa, M.4    Ueda, S.-I.5    Kinoshita, H.6    Fujii, T.7    Kuwano, M.8
  • 39
    • 65349130024 scopus 로고    scopus 로고
    • Proteomic signatures of epidermal growth factor receptor and survival signal pathways correspond to gefitinib sensitivity in head and neck cancer
    • Pernas FG, Allen CT, Winters ME, et al. Proteomic signatures of epidermal growth factor receptor and survival signal pathways correspond to gefitinib sensitivity in head and neck cancer. Clin Cancer Res 2009; 15: 2361-2372.
    • (2009) Clin Cancer Res , vol.15 , pp. 2361-2372
    • Pernas, F.G.1    Allen, C.T.2    Winters, M.E.3
  • 40
    • 0345300537 scopus 로고    scopus 로고
    • Suppression of epidermal growth factor receptor, mitogen-activated protein kinase, and Pak1 pathways and invasiveness of human cutaneous squamous cancer cells by the tyrosine kinase inhibitor ZD1839 (Iressa)
    • Barnes CJ, Bagheri-Yarmand R, Mandal M, et al. Suppression of epidermal growth factor receptor, mitogen-activated protein kinase, and Pak1 pathways and invasiveness of human cutaneous squamous cancer cells by the tyrosine kinase inhibitor ZD1839 (Iressa). Mol Cancer Ther 2003; 2: 345-351.
    • (2003) Mol Cancer Ther , vol.2 , pp. 345-351
    • Barnes, C.J.1    Bagheri-Yarmand, R.2    Mandal, M.3
  • 41
    • 45549084638 scopus 로고    scopus 로고
    • UVA-induced cell cycle progression is mediated by a disintegrin and metalloprotease/epidermal growth factor receptor/AKT/Cyclin D1 pathways in keratinocytes
    • He YY, Council SE, Feng L, et al. UVA-induced cell cycle progression is mediated by a disintegrin and metalloprotease/epidermal growth factor receptor/AKT/Cyclin D1 pathways in keratinocytes. Cancer Res 2008; 68: 3752-3758.
    • (2008) Cancer Res , vol.68 , pp. 3752-3758
    • He, Y.Y.1    Council, S.E.2    Feng, L.3
  • 43
    • 80053132737 scopus 로고    scopus 로고
    • Inhibition of epidermal growth factor receptor and PI3K/Akt signaling suppresses cell proliferation and survival through regulation of Stat3 activation in human cutaneous squamous cell carcinoma
    • Bito T, Sumita N, Ashida M, et al. Inhibition of epidermal growth factor receptor and PI3K/Akt signaling suppresses cell proliferation and survival through regulation of Stat3 activation in human cutaneous squamous cell carcinoma. J Skin Cancer 2011; 2011: 874571.
    • (2011) J Skin Cancer , vol.2011 , pp. 874571
    • Bito, T.1    Sumita, N.2    Ashida, M.3


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