-
1
-
-
33746455271
-
Head and neck cancer: Past, present and future
-
Chin D, Boyle GM, Porceddu S, Theile DR, Parsons PG, Coman WB. Head and neck cancer: past, present and future. Exp Rev Anticancer Ther 2006;6:1111-8.
-
(2006)
Exp Rev Anticancer Ther
, vol.6
, pp. 1111-1118
-
-
Chin, D.1
Boyle, G.M.2
Porceddu, S.3
Theile, D.R.4
Parsons, P.G.5
Coman, W.B.6
-
2
-
-
33144482904
-
Molecular markers of head and neck squamous cell carcinoma: Promising signs in need of prospective evaluation
-
Lothaire P, de Azambuja E, Dequanter D, et al. Molecular markers of head and neck squamous cell carcinoma: promising signs in need of prospective evaluation. Head Neck 2006;28:256-69.
-
(2006)
Head Neck
, vol.28
, pp. 256-269
-
-
Lothaire, P.1
de Azambuja, E.2
Dequanter, D.3
-
3
-
-
17744371649
-
Molecular therapy of head and neck cancer
-
Modjtahedi H. Molecular therapy of head and neck cancer. Cancer Metastasis Rev 2005;24:129-46.
-
(2005)
Cancer Metastasis Rev
, vol.24
, pp. 129-146
-
-
Modjtahedi, H.1
-
5
-
-
21244493635
-
Treatment of hematologic malignancies and solid tumors by inhibiting IGF receptor signaling
-
Mitsiades CS, Mitsiades N. Treatment of hematologic malignancies and solid tumors by inhibiting IGF receptor signaling. Expert Rev Anticancer Ther 2005;5:487-99.
-
(2005)
Expert Rev Anticancer Ther
, vol.5
, pp. 487-499
-
-
Mitsiades, C.S.1
Mitsiades, N.2
-
6
-
-
22044434446
-
Role of insulin-like growth factor 1 receptor signalling in cancer
-
Larsson O, Girnita A, Girnita L. Role of insulin-like growth factor 1 receptor signalling in cancer. Br J Cancer 2005;92:2097-101.
-
(2005)
Br J Cancer
, vol.92
, pp. 2097-2101
-
-
Larsson, O.1
Girnita, A.2
Girnita, L.3
-
7
-
-
0036797073
-
Impact of insulin-like growth factor receptor-I function on angiogenesis, growth, and metastasis of colon cancer
-
Reinmuth N, Fan F, Liu W, et al. Impact of insulin-like growth factor receptor-I function on angiogenesis, growth, and metastasis of colon cancer. Lab Invest 2002;82:1377-89.
-
(2002)
Lab Invest
, vol.82
, pp. 1377-1389
-
-
Reinmuth, N.1
Fan, F.2
Liu, W.3
-
8
-
-
0037470435
-
Requirement of different signaling pathways mediated by insulin-like growth factor-I receptor for proliferation, invasion, and VPF/VEGF expression in a pancreatic carcinoma cell line
-
Zeng H, Datta K, Neid M, Li J, Parangi S, Mukhopadhyay D. Requirement of different signaling pathways mediated by insulin-like growth factor-I receptor for proliferation, invasion, and VPF/VEGF expression in a pancreatic carcinoma cell line. Biochem Biophys Res Commun 2003;302:46-55.
-
(2003)
Biochem Biophys Res Commun
, vol.302
, pp. 46-55
-
-
Zeng, H.1
Datta, K.2
Neid, M.3
Li, J.4
Parangi, S.5
Mukhopadhyay, D.6
-
9
-
-
25844465843
-
Multiple signaling pathways are activated during insulin-like growth factor-I (IGF-I) stimulated breast cancer cell migration
-
Zhang X, Lin M, van Golen KL, Yoshioka K, Itoh K, Yee D. Multiple signaling pathways are activated during insulin-like growth factor-I (IGF-I) stimulated breast cancer cell migration. Breast Cancer Res Treat 2005;93:159-68.
-
(2005)
Breast Cancer Res Treat
, vol.93
, pp. 159-168
-
-
Zhang, X.1
Lin, M.2
van Golen, K.L.3
Yoshioka, K.4
Itoh, K.5
Yee, D.6
-
10
-
-
20944440088
-
Tumor development by transgenic expression of a constitutively active insulin-like growth factor I receptor
-
Carboni JM, Lee AV, Hadsell DL, et al. Tumor development by transgenic expression of a constitutively active insulin-like growth factor I receptor. Cancer Res 2005;65:3781-7.
-
(2005)
Cancer Res
, vol.65
, pp. 3781-3787
-
-
Carboni, J.M.1
Lee, A.V.2
Hadsell, D.L.3
-
11
-
-
0028332092
-
Effect of a null mutation of the insulin-like growth factor I receptor gene on growth and transformation of mouse embryo fibroblasts
-
Sell C, Dumenil G, Deveaud C, et al. Effect of a null mutation of the insulin-like growth factor I receptor gene on growth and transformation of mouse embryo fibroblasts. Mol Cell Biol 1994;14:3604-12.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 3604-3612
-
-
Sell, C.1
Dumenil, G.2
Deveaud, C.3
-
12
-
-
0036669037
-
Control of cell survival by IGF signaling pathways
-
Vincent AM, Feldman EL. Control of cell survival by IGF signaling pathways. Growth Horm IGF Res 2002;12:193-7.
-
(2002)
Growth Horm IGF Res
, vol.12
, pp. 193-197
-
-
Vincent, A.M.1
Feldman, E.L.2
-
13
-
-
0038071783
-
Minireview: Integral membrane proteins that function coordinately with the insulin-like growth factor I receptor to regulate intracellular signaling
-
Clemmons DR, Maile LA. Minireview: Integral membrane proteins that function coordinately with the insulin-like growth factor I receptor to regulate intracellular signaling. Endocrinology 2003;144:1664-70.
-
(2003)
Endocrinology
, vol.144
, pp. 1664-1670
-
-
Clemmons, D.R.1
Maile, L.A.2
-
14
-
-
1042301373
-
A dominant negative type I insulin-like growth factor receptor inhibits metastasis of human cancer cells
-
Sachdev D, Hartell JS, Lee AV, Zhang X , Yee D. A dominant negative type I insulin-like growth factor receptor inhibits metastasis of human cancer cells. J Biol Chem 2004;279:5017-24.
-
(2004)
J Biol Chem
, vol.279
, pp. 5017-5024
-
-
Sachdev, D.1
Hartell, J.S.2
Lee, A.V.3
Zhang, X.4
Yee, D.5
-
15
-
-
23044482717
-
β1A integrin expression is required for type 1 insulin-like growth factor receptor mitogenic and transforming activities and localization to focal contacts
-
Goel HL, Breen M, Zhang J, et al. β1A integrin expression is required for type 1 insulin-like growth factor receptor mitogenic and transforming activities and localization to focal contacts. Cancer Res 2005;65:6692-700.
-
(2005)
Cancer Res
, vol.65
, pp. 6692-6700
-
-
Goel, H.L.1
Breen, M.2
Zhang, J.3
-
16
-
-
0028848659
-
HER-2/neu oncogene characterization in head and neck squamous cell carcinoma
-
Beckhardt RN, Kiyokawa N, Xi L, et al. HER-2/neu oncogene characterization in head and neck squamous cell carcinoma. Arch Otolaryngol Head Neck Surg 1995;121:1265-70.
-
(1995)
Arch Otolaryngol Head Neck Surg
, vol.121
, pp. 1265-1270
-
-
Beckhardt, R.N.1
Kiyokawa, N.2
Xi, L.3
-
17
-
-
2542620761
-
Human epidermal growth factor receptor 2 status modulates subcellular localization of and interaction with estrogen receptor α in breast cancer cells
-
Yang Z, Barnes CJ, Kumar R. Human epidermal growth factor receptor 2 status modulates subcellular localization of and interaction with estrogen receptor α in breast cancer cells. Clin Cancer Res 2004;10:3621-8.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 3621-3628
-
-
Yang, Z.1
Barnes, C.J.2
Kumar, R.3
-
18
-
-
32644442664
-
Estrogen and tamoxifen induce cytoskeletal remodelingand migration in endometrial cancer cells
-
Acconcia F, Barnes CJ, Kumar R. Estrogen and tamoxifen induce cytoskeletal remodelingand migration in endometrial cancer cells. Endocrinology 2006;147:1203-12.
-
(2006)
Endocrinology
, vol.147
, pp. 1203-1212
-
-
Acconcia, F.1
Barnes, C.J.2
Kumar, R.3
-
19
-
-
0034739851
-
Temporal and spatial distribution of activated Pak1 in fibroblasts
-
Sells MA, Pfaff A, Chernoff J. Temporal and spatial distribution of activated Pak1 in fibroblasts. J Cell Biol 2002;151:1449-58.
-
(2002)
J Cell Biol
, vol.151
, pp. 1449-1458
-
-
Sells, M.A.1
Pfaff, A.2
Chernoff, J.3
-
20
-
-
0034680834
-
Regulatable expression of p21-activated kinase-1 promotes anchorage-independent growth and abnormal organization of mitotic spindles in human epithelial breast cancer cells
-
Vadlamudi RK, Adam L, Wang R A, et al. Regulatable expression of p21-activated kinase-1 promotes anchorage-independent growth and abnormal organization of mitotic spindles in human epithelial breast cancer cells. JBiol Chem 2000;2750:36238-440.
-
(2000)
JBiol Chem
, vol.2750
, pp. 36238-36440
-
-
Vadlamudi, R.K.1
Adam, L.2
Wang, R.A.3
-
21
-
-
10344222098
-
The therapeutic potential of agents targeting the type I insulin-like growth factor receptor
-
Zhang H , Yee D. The therapeutic potential of agents targeting the type I insulin-like growth factor receptor. Expert Opin Investig Drugs 2004;13:1569-77.
-
(2004)
Expert Opin Investig Drugs
, vol.13
, pp. 1569-1577
-
-
Zhang, H.1
Yee, D.2
-
22
-
-
23044493251
-
Blocking insulin-like growth factor-I receptor as a strategy for targeting cancer
-
Hofmann F, Garcia-Echeverria C. Blocking insulin-like growth factor-I receptor as a strategy for targeting cancer. Drug Discov Today 2005;10:1041-7.
-
(2005)
Drug Discov Today
, vol.10
, pp. 1041-1047
-
-
Hofmann, F.1
Garcia-Echeverria, C.2
-
23
-
-
21244441508
-
A fully human recombinant IgG-like bispecific antibody to both the epidermal growth factor receptor and the insulin-like growth factor receptor for enhanced antitumor activity
-
Lu D, Zhang HF, Koo H, et al. A fully human recombinant IgG-like bispecific antibody to both the epidermal growth factor receptor and the insulin-like growth factor receptor for enhanced antitumor activity. JBiol Chem 2005;280:19665-72.
-
(2005)
JBiol Chem
, vol.280
, pp. 19665-19672
-
-
Lu, D.1
Zhang, H.F.2
Koo, H.3
-
24
-
-
17144416483
-
In vivo effects of the human type I insulin-like growth factor receptor antibody A12 on androgen-dependent and androgen-independent xenograft human prostate tumors
-
Wu JD, Odman A, Higgins LM, et al. In vivo effects of the human type I insulin-like growth factor receptor antibody A12 on androgen-dependent and androgen-independent xenograft human prostate tumors. Clin Cancer Res 2005;11:3065-74.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 3065-3074
-
-
Wu, J.D.1
Odman, A.2
Higgins, L.M.3
-
25
-
-
9144234724
-
A fully human monoclonal antibody to the insulin-like growth factor I receptor blocks ligand-dependent signaling and inhibits human tumor growth in vivo
-
Burtrum D, Zhu Z, Lu D, et al. A fully human monoclonal antibody to the insulin-like growth factor I receptor blocks ligand-dependent signaling and inhibits human tumor growth in vivo. Cancer Res 2003;63:8912-21.
-
(2003)
Cancer Res
, vol.63
, pp. 8912-8921
-
-
Burtrum, D.1
Zhu, Z.2
Lu, D.3
-
26
-
-
0036162726
-
Detection of new PTEN/MMAC1 mutations in head and neck squamous cell carcinomas with loss of chromosome 10
-
Poetsch M, Lorenz G, Kleist B. Detection of new PTEN/MMAC1 mutations in head and neck squamous cell carcinomas with loss of chromosome 10. Cancer Genet Cytogenet 2002;132:20-4.
-
(2002)
Cancer Genet Cytogenet
, vol.132
, pp. 20-24
-
-
Poetsch, M.1
Lorenz, G.2
Kleist, B.3
-
27
-
-
13244265590
-
Frequent genetic and biochemical alterations of the PI 3-K/AKT/PTEN pathway in head and neck squamous cell carcinoma
-
Pedrero JM, Carracedo DG, Pinto CM, et al. Frequent genetic and biochemical alterations of the PI 3-K/AKT/PTEN pathway in head and neck squamous cell carcinoma. Int J Cancer 2005;114:242-8.
-
(2005)
Int J Cancer
, vol.114
, pp. 242-248
-
-
Pedrero, J.M.1
Carracedo, D.G.2
Pinto, C.M.3
-
28
-
-
33644554236
-
Molecular determinants of Akt-induced keratinocyte transformation
-
Segrelles C, Moral M, Lara MF, et al. Molecular determinants of Akt-induced keratinocyte transformation. Oncogene 2006;25:1174-85.
-
(2006)
Oncogene
, vol.25
, pp. 1174-1185
-
-
Segrelles, C.1
Moral, M.2
Lara, M.F.3
-
30
-
-
0038021222
-
Epithelial cell adhesion and the regulation of gene expression
-
Balda MS, Matter K. Epithelial cell adhesion and the regulation of gene expression. Trends Cell Biol 2003;13:310-8.
-
(2003)
Trends Cell Biol
, vol.13
, pp. 310-318
-
-
Balda, M.S.1
Matter, K.2
-
31
-
-
3142690018
-
Signalling by the type 1 insulin-like growth factor receptor: Interplay with the epidermal growth factor receptor
-
Adams TE, McKern NM, Ward CW. Signalling by the type 1 insulin-like growth factor receptor: interplay with the epidermal growth factor receptor. Growth Factors 2004;22:89-95.
-
(2004)
Growth Factors
, vol.22
, pp. 89-95
-
-
Adams, T.E.1
McKern, N.M.2
Ward, C.W.3
-
32
-
-
0036141447
-
Insulin-like growth factor receptor I mediates resistance to antiepidermal growth factor receptor therapy in primary human glioblastoma cells through continued activation of phosphoinositide 3-kinase signaling
-
Chakravarti A, Loeffler JS, Dyson NJ. Insulin-like growth factor receptor I mediates resistance to antiepidermal growth factor receptor therapy in primary human glioblastoma cells through continued activation of phosphoinositide 3-kinase signaling. Cancer Res 2002;62:200-7.
-
(2002)
Cancer Res
, vol.62
, pp. 200-207
-
-
Chakravarti, A.1
Loeffler, J.S.2
Dyson, N.J.3
-
33
-
-
19944427176
-
Insulin-like growth factor-I receptor signalling and acquired resistance to gefitinib (ZD1839; Iressa) in human breast and prostate cancer cells
-
Jones HE, Goddard L, Gee JM, et al. Insulin-like growth factor-I receptor signalling and acquired resistance to gefitinib (ZD1839; Iressa) in human breast and prostate cancer cells. Endocr Relat Cancer 2004;11:793 -814.
-
(2004)
Endocr Relat Cancer
, vol.11
, pp. 793-814
-
-
Jones, H.E.1
Goddard, L.2
Gee, J.M.3
-
34
-
-
33646871998
-
Potential cross-talk between insulin-like growth factor receptor type1 and epidermal growth factor receptor in progression and metastasis of pancreatic cancer
-
Ueda S, Hatsuse K, Tsuda H, et al. Potential cross-talk between insulin-like growth factor receptor type1 and epidermal growth factor receptor in progression and metastasis of pancreatic cancer. Mod Pathol 2006;19:788-96.
-
(2006)
Mod Pathol
, vol.19
, pp. 788-796
-
-
Ueda, S.1
Hatsuse, K.2
Tsuda, H.3
-
35
-
-
17844406391
-
Phosphotyrosine signaling networks in epidermal growth factor receptor overexpressing squamous carcinoma cells
-
Thelemann A, Petti F, Griffin G, et al. Phosphotyrosine signaling networks in epidermal growth factor receptor overexpressing squamous carcinoma cells. Mol Cell Proteomics 2005;4:356-76.
-
(2005)
Mol Cell Proteomics
, vol.4
, pp. 356-376
-
-
Thelemann, A.1
Petti, F.2
Griffin, G.3
-
36
-
-
0036561431
-
Molecular inhibition of angiogenesis and metastatic potential in human squamous cell carcinomas after epidermal growth factor receptor blockade
-
Huang SM, Li J, Harari PM. Molecular inhibition of angiogenesis and metastatic potential in human squamous cell carcinomas after epidermal growth factor receptor blockade. Mol Cancer Ther 2002;1:507-14.
-
(2002)
Mol Cancer Ther
, vol.1
, pp. 507-514
-
-
Huang, S.M.1
Li, J.2
Harari, P.M.3
-
37
-
-
0036094194
-
Enhanced antitumor activity of anti-epidermal growth factor receptor monoclonal antibody IMC-C225 in combination with irinotecan (CPT-11) against human colorectal tumor xenografts
-
Prewett MC, Hooper AT, Bassi R, Ellis LM, Waksal HW, Hicklin DJ. Enhanced antitumor activity of anti-epidermal growth factor receptor monoclonal antibody IMC-C225 in combination with irinotecan (CPT-11) against human colorectal tumor xenografts. Clin Cancer Res 2002;8:994-1003.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 994-1003
-
-
Prewett, M.C.1
Hooper, A.T.2
Bassi, R.3
Ellis, L.M.4
Waksal, H.W.5
Hicklin, D.J.6
-
38
-
-
0034235955
-
Epidermal growth factor receptor blockade by antibody IMC-C225 inhibits growth of a human pancreatic carcinoma xenograft in nude mice
-
Overholser JP, Prewett MC, Hooper AT, Waksal HW, Hicklin DJ. Epidermal growth factor receptor blockade by antibody IMC-C225 inhibits growth of a human pancreatic carcinoma xenograft in nude mice. Cancer 2000;89:74-82.
-
(2000)
Cancer
, vol.89
, pp. 74-82
-
-
Overholser, J.P.1
Prewett, M.C.2
Hooper, A.T.3
Waksal, H.W.4
Hicklin, D.J.5
-
39
-
-
0032407024
-
Mouse-human chimeric anti-epidermal growth factor receptor antibody C225 inhibits the growth of human renal cell carcinoma xenografts in nude mice
-
Prewett M, Rothman M, Waksal H, Feldman M, Bander NH, Hicklin DJ. Mouse-human chimeric anti-epidermal growth factor receptor antibody C225 inhibits the growth of human renal cell carcinoma xenografts in nude mice. Clin Cancer Res 1998;4:2957-66.
-
(1998)
Clin Cancer Res
, vol.4
, pp. 2957-2966
-
-
Prewett, M.1
Rothman, M.2
Waksal, H.3
Feldman, M.4
Bander, N.H.5
Hicklin, D.J.6
-
40
-
-
31544448038
-
Enhancement of antitumor activity of the anti-EGF receptor monoclonal antibody cetuximab/C225 by perifosine in PTEN-deficient cancer cells
-
Li X, Luwor R, Lu Y, Liang K , Fan Z. Enhancement of antitumor activity of the anti-EGF receptor monoclonal antibody cetuximab/C225 by perifosine in PTEN-deficient cancer cells. Oncogene 2006;25:525-35.
-
(2006)
Oncogene
, vol.25
, pp. 525-535
-
-
Li, X.1
Luwor, R.2
Lu, Y.3
Liang, K.4
Fan, Z.5
-
41
-
-
26844487041
-
Insulin-like growth factor-I receptor signaling in tamoxifen-resistant breast cancer: A supporting role to the epidermal growth factor receptor
-
Knowlden JM, Hutcheson IR, Barrow D, Gee JM, Nicholson RI. Insulin-like growth factor-I receptor signaling in tamoxifen-resistant breast cancer: a supporting role to the epidermal growth factor receptor. Endocrinology 2005;146:4609-18.
-
(2005)
Endocrinology
, vol.146
, pp. 4609-4618
-
-
Knowlden, J.M.1
Hutcheson, I.R.2
Barrow, D.3
Gee, J.M.4
Nicholson, R.I.5
-
42
-
-
33645224054
-
Insulin-like growth factor 1 receptor signaling regulates skin development and inhibits skin keratinocyte differentiation
-
Sadagurski M, Yakar S, Weingarten G, et al. Insulin-like growth factor 1 receptor signaling regulates skin development and inhibits skin keratinocyte differentiation. Mol Cell Biol 2006;26:2675-87.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 2675-2687
-
-
Sadagurski, M.1
Yakar, S.2
Weingarten, G.3
-
43
-
-
33644555493
-
Down-regulation of insulin receptor by antibodies against the type I insulin-like growth factor receptor: Implications for anti-insulin-like growth factor therapy in breast cancer
-
Sachdev D, Singh R, Fujita-Yamaguchi Y, Yee D. Down-regulation of insulin receptor by antibodies against the type I insulin-like growth factor receptor: implications for anti-insulin-like growth factor therapy in breast cancer. Cancer Res 2006;66:2391-402.
-
(2006)
Cancer Res
, vol.66
, pp. 2391-2402
-
-
Sachdev, D.1
Singh, R.2
Fujita-Yamaguchi, Y.3
Yee, D.4
-
44
-
-
28544444712
-
Type I insulin-like growth factor receptor as a therapeutic target in cancer
-
Miller BS, Yee D. Type I insulin-like growth factor receptor as a therapeutic target in cancer. Cancer Res 2005;65:10123-7.
-
(2005)
Cancer Res
, vol.65
, pp. 10123-10127
-
-
Miller, B.S.1
Yee, D.2
|