The insulin-like growth factor-I receptor inhibitor picropodophyllin causes tumor regression and attenuates mechanisms involved in invasion of uveal melanoma cells

Acta Ophthalmologica

Volumn 86, Issue THESIS 4, 2008, Pages 26-34

  Girnita, Ada ^b   All Ericsson, Charlotta ^c   Economou, Mario A ^c   Åström, Kristina ^b   Axelson, Magnus ^b   Seregard, Stefan ^c   Larsson, Olle ^a,b   Girnita, Leonard ^b  

^a KAROLINSKA INSTITUTE   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c ST ERIK S EYE HOSPITAL   (Sweden)

Author keywords

IGF 1R; Metastasis; Picrodopophyllin; Uveal melanoma

Indexed keywords

COLLAGEN TYPE 1; COLLAGEN TYPE 4; FIBRONECTIN; GELATINASE A; INTEGRIN; LAMININ; PICROPODOPHYLLIN; PROTEIN INHIBITOR; SCLEROPROTEIN; SOMATOMEDIN C RECEPTOR; UNCLASSIFIED DRUG; VITRONECTIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BASEMENT MEMBRANE; CANCER CELL CULTURE; CANCER INHIBITION; CELL ADHESION; CELL INVASION; CELL MIGRATION; CELL SURVIVAL; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; ENDOTHELIUM CELL; ENZYME ACTIVITY; HUMAN; HUMAN CELL; LIVER METASTASIS; MELANOMA CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; TUMOR REGRESSION; UVEA MELANOMA; XENOGRAFT;

ANIMALS; CELL ADHESION; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; EXTRACELLULAR MATRIX PROTEINS; HUMANS; MATRIX METALLOPROTEINASE 2; MELANOMA; MICE; MICE, SCID; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; NEOPLASM TRANSPLANTATION; PHOSPHORYLATION; PODOPHYLLOTOXIN; RECEPTOR, IGF TYPE 1; TRANSPLANTATION, HETEROLOGOUS; UVEAL NEOPLASMS;

EID: 56849130445     PISSN: 1755375X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1755-3768.2008.01183.x     Document Type: Article

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