-
1
-
-
0028890744
-
The insulin-like growth factor 1 receptor: A key to tumor growth?
-
Baserga, R. The insulin-like growth factor 1 receptor: a key to tumor growth? Cancer Res., 55: 249-252, 1995.
-
(1995)
Cancer Res.
, vol.55
, pp. 249-252
-
-
Baserga, R.1
-
2
-
-
0034693756
-
The contradictions of the insulin-like growth factor 1 receptor
-
Baserga, R. The contradictions of the insulin-like growth factor 1 receptor. Oncogene, 19: 5574-5581, 2000.
-
(2000)
Oncogene
, vol.19
, pp. 5574-5581
-
-
Baserga, R.1
-
3
-
-
0037816235
-
Mdm2-dependent ubiquitination and degradation of the insulin-like growth factor 1 receptor
-
Girnita, L., Girnita, A., and Larsson, O. Mdm2-dependent ubiquitination and degradation of the insulin-like growth factor 1 receptor. Proc. Natl. Acad. Sci. USA, 100: 8247-8252, 2003.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 8247-8252
-
-
Girnita, L.1
Girnita, A.2
Larsson, O.3
-
4
-
-
0034665348
-
Increased expression of insulin-like growth factor 1 receptor in malignant cells expressing aberrant p53: Functional impact
-
Girnita, L., Gimita, A., Brodin, B., Xie, Y., Nilsson, G., Dricu, A., Lundeberg, J., Wejde, J., Bartolazzi, A., Wiman, K. G., and Larsson, O. Increased expression of insulin-like growth factor 1 receptor in malignant cells expressing aberrant p53: functional impact. Cancer Res., 60: 5278-5283, 2000.
-
(2000)
Cancer Res.
, vol.60
, pp. 5278-5283
-
-
Girnita, L.1
Gimita, A.2
Brodin, B.3
Xie, Y.4
Nilsson, G.5
Dricu, A.6
Lundeberg, J.7
Wejde, J.8
Bartolazzi, A.9
Wiman, K.G.10
Larsson, O.11
-
5
-
-
0034692430
-
Role of the insulin-like growth factor family in cancer development and progression
-
Yu, H., and Rohan, T. Role of the insulin-like growth factor family in cancer development and progression. J. Natl. Cancer Inst., 92: 1472-1489, 2000.
-
(2000)
J. Natl. Cancer Inst.
, vol.92
, pp. 1472-1489
-
-
Yu, H.1
Rohan, T.2
-
6
-
-
0028957113
-
Molecular and cellular aspects of the insulin-like growth factor 1 receptor
-
LeRoith, D., Werner, H., Beitner-Johnson, D., and Roberts, C. T., Jr. Molecular and cellular aspects of the insulin-like growth factor 1 receptor. Endocr. Rev., 16: 143-163, 1995.
-
(1995)
Endocr. Rev.
, vol.16
, pp. 143-163
-
-
LeRoith, D.1
Werner, H.2
Beitner-Johnson, D.3
Roberts Jr., C.T.4
-
7
-
-
0022800838
-
Insulin-like growth factor 1 receptor primary structure: Comparison with insulin receptor suggests structural determinants that define functional specificity
-
Ullrich, A., Gray, A., Tam, A. W., Yang-Feng, T., Tsubokawa, M., Collins, C., Henzel, W., Le Bon, T., Kathuria, S., Chen, E., et al. Insulin-like growth factor 1 receptor primary structure: comparison with insulin receptor suggests structural determinants that define functional specificity. EMBO J., 5: 2503-2512, 1986.
-
(1986)
EMBO J.
, vol.5
, pp. 2503-2512
-
-
Ullrich, A.1
Gray, A.2
Tam, A.W.3
Yang-Feng, T.4
Tsubokawa, M.5
Collins, C.6
Henzel, W.7
Le Bon, T.8
Kathuria, S.9
Chen, E.10
-
8
-
-
0035090634
-
Limited redundancy of survival signals from the type 1 insulin-like growth factor receptor
-
Navarro, M., and Baserga, R. Limited redundancy of survival signals from the type 1 insulin-like growth factor receptor. Endocrinology, 142: 1073-1081, 2001.
-
(2001)
Endocrinology
, vol.142
, pp. 1073-1081
-
-
Navarro, M.1
Baserga, R.2
-
9
-
-
0035185571
-
Structure and autoregulation of the insulin-like growth factor 1 receptor kinase
-
Favelyukis, S., Till, J. H., Hubbard, S. R., and Miller, W. T. Structure and autoregulation of the insulin-like growth factor 1 receptor kinase. Nat. Struct. Biol., 8: 1058-1063, 2001.
-
(2001)
Nat. Struct. Biol.
, vol.8
, pp. 1058-1063
-
-
Favelyukis, S.1
Till, J.H.2
Hubbard, S.R.3
Miller, W.T.4
-
10
-
-
0034719133
-
Substrate competitive inhibitors of IGF-1 receptor kinase
-
Blum, G., Gazit, A., and Levitzki, A. Substrate competitive inhibitors of IGF-1 receptor kinase. Biochemistry, 39: 15705-15712, 2000.
-
(2000)
Biochemistry
, vol.39
, pp. 15705-15712
-
-
Blum, G.1
Gazit, A.2
Levitzki, A.3
-
11
-
-
0035165210
-
Mechanism-based design of a protein kinase inhibitor
-
Parang, K., Till, J. H., Ablooglu, A. J., Kohanski, R. A., Hubbard, S. R., and Cole, P. A. Mechanism-based design of a protein kinase inhibitor. Nat. Struct. Biol., 8: 37-41, 2001.
-
(2001)
Nat. Struct. Biol.
, vol.8
, pp. 37-41
-
-
Parang, K.1
Till, J.H.2
Ablooglu, A.J.3
Kohanski, R.A.4
Hubbard, S.R.5
Cole, P.A.6
-
12
-
-
0034713780
-
Tamoxifen-induced cell death in malignant melanoma cells: Possible involvement of the insulin-like growth factor-1 (IGF-1) pathway
-
Kanter-Lewensohn, L., Girnita, L., Girnita, A., Dricu, A., Olsson, G., Leech, L., Nilsson, G., Hilding, A., Wejde, J., Brismar, K., and Larsson, O. Tamoxifen-induced cell death in malignant melanoma cells: possible involvement of the insulin-like growth factor-1 (IGF-1) pathway. Mol. Cell. Endocrinol., 165: 131-137, 2000.
-
(2000)
Mol. Cell. Endocrinol.
, vol.165
, pp. 131-137
-
-
Kanter-Lewensohn, L.1
Girnita, L.2
Girnita, A.3
Dricu, A.4
Olsson, G.5
Leech, L.6
Nilsson, G.7
Hilding, A.8
Wejde, J.9
Brismar, K.10
Larsson, O.11
-
13
-
-
0020026453
-
Origin of lignans in mammals and identification of a precursor from plants
-
Axelson, M., Sjövall, J., Gustafsson, B. E., and Setchell, K. D. Origin of lignans in mammals and identification of a precursor from plants. Nature (Lond.), 298: 659-660, 1982.
-
(1982)
Nature (Lond.)
, vol.298
, pp. 659-660
-
-
Axelson, M.1
Sjövall, J.2
Gustafsson, B.E.3
Setchell, K.D.4
-
14
-
-
0021235849
-
Soya - A dietary source of the non-steroidal oestrogen equol in man and animals
-
Axelson, M., Sjövall, J., Gustafsson, B. E., and Setchell, K. D. Soya-a dietary source of the non-steroidal oestrogen equol in man and animals. J. Endocrinol., 102: 49-56, 1984.
-
(1984)
J. Endocrinol.
, vol.102
, pp. 49-56
-
-
Axelson, M.1
Sjövall, J.2
Gustafsson, B.E.3
Setchell, K.D.4
-
15
-
-
77049217359
-
The biological effects of and the chemical composition of podophyllin
-
Kelly, M. G., and Hartwell, J. L. The biological effects of and the chemical composition of podophyllin. J. Natl. Cancer Inst., 14: 967-1011, 1954.
-
(1954)
J. Natl. Cancer Inst.
, vol.14
, pp. 967-1011
-
-
Kelly, M.G.1
Hartwell, J.L.2
-
16
-
-
0012789257
-
Response of patients with advanced neoplasms to the intravenous administration of α-peltatin
-
Greenspan, E. M., Colsky, J., Schoenbach, E. B., and Sherar, M. J. Response of patients with advanced neoplasms to the intravenous administration of α-peltatin. J. Natl. Cancer Inst., 16: 1257-1275. 1954.
-
(1954)
J. Natl. Cancer Inst.
, vol.16
, pp. 1257-1275
-
-
Greenspan, E.M.1
Colsky, J.2
Schoenbach, E.B.3
Sherar, M.J.4
-
17
-
-
0017601419
-
Tubulin binding affinities of podophyllotoxin and colchicine analogues
-
Kelleher, J. K. Tubulin binding affinities of podophyllotoxin and colchicine analogues. Mol. Pharmacol., 13: 232-241, 1977.
-
(1977)
Mol. Pharmacol.
, vol.13
, pp. 232-241
-
-
Kelleher, J.K.1
-
18
-
-
84959841266
-
The biological effects of some podophyllin compounds and their dependence on chemical structure
-
Seidlova-Masinova, V., Malinsky, J., and Santavy, F. The biological effects of some podophyllin compounds and their dependence on chemical structure. J. Natl. Cancer Inst., 18: 359-371, 1957.
-
(1957)
J. Natl. Cancer Inst.
, vol.18
, pp. 359-371
-
-
Seidlova-Masinova, V.1
Malinsky, J.2
Santavy, F.3
-
20
-
-
0017253461
-
Investigational drugs under study by the United States National Cancer Institute
-
Carter, S. K., and Slavik, M. Investigational drugs under study by the United States National Cancer Institute. Cancer Treat. Rev., 3: 43-60, 1976.
-
(1976)
Cancer Treat. Rev.
, vol.3
, pp. 43-60
-
-
Carter, S.K.1
Slavik, M.2
-
21
-
-
0032168167
-
Eloposide: Four decades of development of a topoisomerase II inhibitor
-
Hande, K. R. Eloposide: four decades of development of a topoisomerase II inhibitor. Eur. J. Cancer, 34: 1514-1521, 1998.
-
(1998)
Eur. J. Cancer
, vol.34
, pp. 1514-1521
-
-
Hande, K.R.1
-
22
-
-
0021329758
-
Comparison of cytotoxicity and DNA breakage activity of congeners of podophyllotoxin including VP-16-213 and VM-213: A quantitative structure-activity relationship
-
Long, B. H., Musial, S. T., and Brattain, M. G. Comparison of cytotoxicity and DNA breakage activity of congeners of podophyllotoxin including VP-16-213 and VM-213: A quantitative structure-activity relationship. Biochemistry, 23: 1183-1188, 1984.
-
(1984)
Biochemistry
, vol.23
, pp. 1183-1188
-
-
Long, B.H.1
Musial, S.T.2
Brattain, M.G.3
-
24
-
-
0023009585
-
Thermal chemistry of podophyllotoxin in ethanol and a comparison of the cytostatic activity of the thennolysis products
-
Buchardt, O., Jensen, R. B., Hansen, H. F., Nielsen, P. E., Andersen, D., and Chinoin, I. Thermal chemistry of podophyllotoxin in ethanol and a comparison of the cytostatic activity of the thennolysis products. J. Pharm. Sci., 75: 1076-1080, 1986.
-
(1986)
J. Pharm. Sci.
, vol.75
, pp. 1076-1080
-
-
Buchardt, O.1
Jensen, R.B.2
Hansen, H.F.3
Nielsen, P.E.4
Andersen, D.5
Chinoin, I.6
-
25
-
-
0031079684
-
The IGF-1 receptor in mitogenesis and transformation of mouse embryo cells: Role of receptor number
-
Rubini, M., Hongo, A., D'Ambrosio, C., and Baserga, R. The IGF-1 receptor in mitogenesis and transformation of mouse embryo cells: role of receptor number. Exp. Cell Res., 230: 284-292, 1997.
-
(1997)
Exp. Cell Res.
, vol.230
, pp. 284-292
-
-
Rubini, M.1
Hongo, A.2
D'Ambrosio, C.3
Baserga, R.4
-
26
-
-
0030952501
-
Insulin-like growth factor 1 receptor signaling in transformation by src oncogenes
-
Valentinis, B., Morrione, A., Taylor, S. J., and Baserga, R. Insulin-like growth factor 1 receptor signaling in transformation by src oncogenes. Mol. Cell. Biol., 17: 3744-3754, 1997.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 3744-3754
-
-
Valentinis, B.1
Morrione, A.2
Taylor, S.J.3
Baserga, R.4
-
27
-
-
0014949207
-
Cleavage of structural proteins during the assembly of the head of bacteriophage T4
-
Laemmli, U. K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (Lond.), 227: 680-685, 1970.
-
(1970)
Nature (Lond.)
, vol.227
, pp. 680-685
-
-
Laemmli, U.K.1
-
28
-
-
0035971083
-
Growth factors regulate heterogeneous nuclear ribonucleoprotein K expression and function
-
Mandal, M., Vadlamudi, R., Nguyen, D., Wang, R. A., Costa, L., Bagheri-Yarmand, R., Mendelsohn, J., and Kumar, R. Growth factors regulate heterogeneous nuclear ribonucleoprotein K expression and function. J. Biol. Chem., 276: 9699-9704, 2001.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 9699-9704
-
-
Mandal, M.1
Vadlamudi, R.2
Nguyen, D.3
Wang, R.A.4
Costa, L.5
Bagheri-Yarmand, R.6
Mendelsohn, J.7
Kumar, R.8
-
29
-
-
0030909657
-
Specific inhibition of insulin-like growth factor-1 and insulin receptor tyrosine kinase activity and biological function by tyrphostins
-
Parrizas, M., Gazit, A., Levitzki, A., Wertheimer, E., and LeRoith, D. Specific inhibition of insulin-like growth factor-1 and insulin receptor tyrosine kinase activity and biological function by tyrphostins. Endocrinology, 138: 1427-1433, 1997.
-
(1997)
Endocrinology
, vol.138
, pp. 1427-1433
-
-
Parrizas, M.1
Gazit, A.2
Levitzki, A.3
Wertheimer, E.4
LeRoith, D.5
-
30
-
-
0025799991
-
An improved colorimetric assay for cell proliferation and viability utilizing the tetrazolium salt XTT
-
Roehm, N. W., Rodgers, G. H., Hatfield, S. M., and Glasebrook, A. L. An improved colorimetric assay for cell proliferation and viability utilizing the tetrazolium salt XTT. J. Immunol. Methods, 142: 257-265, 1991.
-
(1991)
J. Immunol. Methods
, vol.142
, pp. 257-265
-
-
Roehm, N.W.1
Rodgers, G.H.2
Hatfield, S.M.3
Glasebrook, A.L.4
-
31
-
-
0033883776
-
Cherrington SU6668 is a potent antiangiogenic and antitumor agent that induces regression of established tumors
-
Laird, A. D., Vajkoczy, P., Shawvcr, L. K., Thurnher, A., Liang, C., Mohammadi, M., Schlessinger, J., Ullrich, A., Hubbard, S. R., Blake, R. A., Fong, T. A., Strawn, L. M., Sun, L., Tang, C., Hawtin, R., Tang, F., Shenoy, N., Hirth, K. P., McMahon, G., and Cherrington SU6668 is a potent antiangiogenic and antitumor agent that induces regression of established tumors. Cancer Res., 60: 4152-4160, 2000.
-
(2000)
Cancer Res.
, vol.60
, pp. 4152-4160
-
-
Laird, A.D.1
Vajkoczy, P.2
Shawvcr, L.K.3
Thurnher, A.4
Liang, C.5
Mohammadi, M.6
Schlessinger, J.7
Ullrich, A.8
Hubbard, S.R.9
Blake, R.A.10
Fong, T.A.11
Strawn, L.M.12
Sun, L.13
Tang, C.14
Hawtin, R.15
Tang, F.16
Shenoy, N.17
Hirth, K.P.18
McMahon, G.19
-
32
-
-
1642530368
-
-
PCT WO 02/102904 A1 (27.12.2002): New use of specific cyclolignans
-
PCT WO 02/102904 A1 (27.12.2002): New use of specific cyclolignans.
-
-
-
-
33
-
-
1642530369
-
-
PCT WO 02/102805 A1 (27.12.2002): New use of cyclolignans and new cyclolignans
-
PCT WO 02/102805 A1 (27.12.2002): New use of cyclolignans and new cyclolignans.
-
-
-
-
34
-
-
0033951649
-
The insulin-like growth factor axis: A review of atherosclerosis and restenosis
-
Bayes-Genis, A., Conover, C. A., and Schwartz, R. S. The insulin-like growth factor axis: A review of atherosclerosis and restenosis. Circ. Res., 86: 125-130, 2000.
-
(2000)
Circ. Res.
, vol.86
, pp. 125-130
-
-
Bayes-Genis, A.1
Conover, C.A.2
Schwartz, R.S.3
-
35
-
-
0035843913
-
Defect in insulin-like growth factor-1 survival mechanism in atherosclerotic plaque-derived vascular smooth muscle cells is mediated by reduced surface binding and signaling
-
Patel, V. A., Zhang, Q. J., Siddle, K., Soos, M. A., Goddard, M., Weissberg, P. L., and Bennett, M. R. Defect in insulin-like growth factor-1 survival mechanism in atherosclerotic plaque-derived vascular smooth muscle cells is mediated by reduced surface binding and signaling. Circ. Res., 88: 895-902, 2001.
-
(2001)
Circ. Res.
, vol.88
, pp. 895-902
-
-
Patel, V.A.1
Zhang, Q.J.2
Siddle, K.3
Soos, M.A.4
Goddard, M.5
Weissberg, P.L.6
Bennett, M.R.7
-
36
-
-
0034123916
-
Reversal of epidermal hyperproliferation in psoriasis by insulin-like growth factor 1 receptor antisense oligonucleotides
-
Wraight, C. J., White, P. J., McKean, S. C., Fogarty, R. D., Venables, D. J., Liepe, I. J., Edmondson, S. R., and Werther, G. A. Reversal of epidermal hyperproliferation in psoriasis by insulin-like growth factor 1 receptor antisense oligonucleotides. Nat. Biotechnol., 18: 521-526, 2000.
-
(2000)
Nat. Biotechnol.
, vol.18
, pp. 521-526
-
-
Wraight, C.J.1
White, P.J.2
McKean, S.C.3
Fogarty, R.D.4
Venables, D.J.5
Liepe, I.J.6
Edmondson, S.R.7
Werther, G.A.8
-
37
-
-
0035040518
-
Is the acromegalic cardiomyopathy reversible? Effect of 5-year normalization of growth hormone and insulin-like growth factor 1 levels on cardiac performance
-
Colao, A., Cuocolo, A., Marzullo, P., Nicolai, E., Ferone, D., Della Morte, A. M., Pivonello, R., Salvatore, M., and Lombardi, G. Is the acromegalic cardiomyopathy reversible? Effect of 5-year normalization of growth hormone and insulin-like growth factor 1 levels on cardiac performance. J. Clin. Endocrinol. Metab., 86: 1551-1557, 2001.
-
(2001)
J. Clin. Endocrinol. Metab.
, vol.86
, pp. 1551-1557
-
-
Colao, A.1
Cuocolo, A.2
Marzullo, P.3
Nicolai, E.4
Ferone, D.5
Della Morte, A.M.6
Pivonello, R.7
Salvatore, M.8
Lombardi, G.9
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