Effects of Korean red ginseng extract on the prevention of atopic dermatitis and its mechanism on early lesions in a murine model

Journal of Ethnopharmacology

Volumn 145, Issue 1, 2013, Pages 294-302

  Cho, Eujin ^a   Cho, Sang Hyun ^a  

^a Bupyeong gu   (South Korea)

Author keywords

Allergy; Atopic dermatitis; Dermatosis; Inflammation; Korean red ginseng

Indexed keywords

GAMMA INTERFERON; GINSENG EXTRACT; IMMUNOGLOBULIN E; INTERLEUKIN 17; INTERLEUKIN 4; KOREAN RED GINSENG EXTRACT; MESSENGER RNA; THYMIC STROMAL LYMPHOPOIETIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATOPIC DERMATITIS; CONTROLLED STUDY; DOWN REGULATION; FEMALE; GINSENG; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; KOREAN RED GINSENG; LYMPHOCYTIC INFILTRATION; MOUSE; NONHUMAN; PROTEIN EXPRESSION; SKIN DEFECT; SKIN WATER LOSS;

ANIMALS; CYTOKINES; DERMATITIS, ATOPIC; DISEASE MODELS, ANIMAL; FEMALE; IMMUNOGLOBULIN E; INTERFERON-GAMMA; INTERLEUKIN-17; INTERLEUKIN-4; LYMPHOCYTES; MICE; MICE, INBRED STRAINS; PANAX; PHYTOTHERAPY; PICRYL CHLORIDE; PLANT EXTRACTS; PLANT ROOTS; SEVERITY OF ILLNESS INDEX; SKIN; WATER;

MURINAE; MUS; PANAX GINSENG;

EID: 84871301076     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2012.11.006     Document Type: Article

References (34)

1. W. Abramovits Atopic dermatitis Journal of the American Academy of Dermatology 53 2005 S86 S93
2. W. Abramovits A clinician's paradigm in the treatment of atopic dermatitis Journal of the American Academy of Dermatology 53 2005 S70 S77
3. K.T. Amor, C. Ryan, and A. Menter The use of cyclosporine in dermatology: part I Journal of the American Academy of Dermatology 63 2010 925 946
4. I. Angelova-Fischer, A. Bauer, U.C. Hipler, I. Petrov, J. Kazandjieva, and T. Bruckner The objective severity assessment of atopic dermatitis (OSAAD) score: validity, reliability and sensitivity in adult patients with atopic dermatitis British Journal of Dermatology 153 2005 767 773
5. E.A. Bae, M.J. Han, Y.W. Shin, and D.H. Kim Inhibitory effects of Korean red ginseng and its genuine constituents ginsenosides Rg3, Rf, and Rh2 in mouse passive cutaneous anaphylaxis reaction and contact dermatitis models Biological and Pharmaceutical Bulletin 29 2006 1862 1867
6. T. Bieber Atopic dermatitis New England Journal of Medicine 358 2008 1483 1494
7. M. Boguniewicz, and D.Y. Leung Atopic dermatitis: a disease of altered skin barrier and immune dysregulation Immunological Reviews 242 2011 233 246
8. M. Caproni, E. Salvatore, C. Cardinali, B. Brazzini, and P. Fabbri Soluble CD30 and cyclosporine in severe atopic dermatitis International Archives of Allergy and Immunology 121 2000 324 328
9. S. Ehser, J.J. Chuang, C. Kleist, F. Sandra-Petrescu, M. Iancu, and D. Wang Suppressive dendritic cells as a tool for controlling allograft rejection in organ transplantation: promises and difficulties Human Immunology 69 2008 165 173
10. P.M. Elias, Y. Hatano, and M.L. Williams Basis for the barrier abnormality in atopic dermatitis: outside-inside-outside pathogenic mechanisms Journal of Allergy and Clinical Immunology 121 2008 1337 1343
11. Y. Guo, P. Xiao, S. Lei, F. Deng, G.G. Xiao, and Y. Liu How is mRNA expression predictive for protein expression? A correlation study on human circulating monocytes Acta Biochimica et Biophysica Sinica 40 2008 426 436
12. E. Guttman-Yassky, K.E. Nograles, and J.G. Krueger Contrasting pathogenesis of atopic dermatitis and psoriasis - part I: clinical and pathologic concepts Journal of Allergy and Clinical Immunology 127 2011 1110 1118
13. D.J. Hijnen, E. Knol, C. Bruijnzeel-Koomen, and M. de Bruin-Weller Cyclosporin A treatment is associated with increased serum immunoglobulin E levels in a subgroup of atopic dermatitis patients Dermatitis: contact, Atopic, Occupational, Drug: Official journal of the American Contact Dermatitis Society, North American Contact Dermatitis Group 18 2007 163 165
14. B. Homey, M. Steinhoff, T. Ruzicka, and D.Y. Leung Cytokines and chemokines orchestrate atopic skin inflammation Journal of Allergy and Clinical Immunology 118 2006 178 189
15. H.S. Kim, D.H. Kim, B.K. Kim, S.K. Yoon, M.H. Kim, and J.Y. Lee Effects of topically applied Korean red ginseng and its genuine constituents on atopic dermatitis-like skin lesions in NC/Nga mice International Immunopharmacology 11 2011 280 285
16. J. Koo, and S. Arain Traditional Chinese medicine in dermatology Clinics in Dermatology 17 1999 21 27
17. C.H. Lee, H.Y. Chuang, C.C. Shih, S.B. Jong, C.H. Chang, and H.S. Yu Transepidermal water loss, serum IgE and beta-endorphin as important and independent biological markers for development of itch intensity in atopic dermatitis British Journal of Dermatology 154 2006 1100 1107
18. C.H. Lee, and H.S. Yu Biomarkers for itch and disease severity in atopic dermatitis Current Problems in Dermatology 41 2011 136 148
19. J.H. Lee, and S.H. Cho Korean red ginseng extract ameliorates skin lesions in NC/Nga mice: an atopic dermatitis model Journal of Ethnopharmacology 133 2011 810 817
20. Y.J. Liu Thymic stromal lymphopoietin: master switch for allergic inflammation Journal of Experimental Medicine 203 2006 269 273
21. H. Matsuda, K. Samukawa, and M. Kubo Anti-inflammatory activity of ginsenoside Ro Planta Medica 56 1990 19 23
22. N. Novak An update on the role of human dendritic cells in patients with atopic dermatitis Journal of Allergy and Clinical Immunology 2012 129, 879-886
23. N. Novak, and T. Bieber The role of dendritic cell subtypes in the pathophysiology of atopic dermatitis Journal of the American Academy of Dermatology 53 2005 S171 S176
24. N. Novak, and D.Y. Leung Advances in atopic dermatitis Current Opinion in Immunology 23 2011 778 783
25. M. Ogawa, P.A. Berger, O.R. McIntyre, W.E. Clendenning, and K. Ishizaka IgE in atopic dermatitis Archives of Dermatology 103 1971 575 580
26. E.K. Park, M.K. Choo, E.J. Kim, M.J. Han, and D.H. Kim Antiallergic activity of ginsenoside Rh2 Biological and Pharmaceutical Bulletin 26 2003 1581 1584
27. H.J. Park, H.E. Byeon, K.W. Choi, D.K. Rhee, and K.R. Lee Inhibitory effects of ginsenoside Rb1 on atopic dermatitis-like skin lesions in mice Journal of Ginseng Research 34 2010 363 368
28. S. Shibata, M. Fujita, H. Itokawa, O. Tanaka, and T. Ishii Studies on the constituents of Japanese and Chinses crude drugs. XI. Panaxadiol, a sapogenin of ginseng roots Chemical and Pharmaceutical Bulletin 11 1963 759 761
29. E.H. Sohn, S.A. Jang, C.H. Lee, K.H. Jang, S.C. Kang, and H.J. Park Effects of Korean red ginseng extract for the treatment of atopic dermatitis-like skin lesions in mice Journal of Ginseng Research 35 2011 479 486
30. J.L. Sugarman, J.W. Fluhr, A.J. Fowler, T. Bruckner, T.L. Diepgen, and M.L. Williams The objective severity assessment of atopic dermatitis score: an objective measure using permeability barrier function and stratum corneum hydration with computer-assisted estimates for extent of disease Archives of Dermatology 139 2003 1417 1422
31. H.C. Williams Evening primrose oil for atopic dermatitis: time to say goodnight BMJ: British Medical Journal 327 2003 1358 1359
32. H.C. Williams, and D.J. Grindlay What's new in atopic eczema? An analysis of the clinical significance of systematic reviews on atopic eczema published in 2006 and 2007 Clinical and Experimental Dermatology 33 2008 685 688
33. K. Yamanaka, and H. Mizutani The role of cytokines/chemokines in the pathogenesis of atopic dermatitis Current Problems in Dermatology 41 2011 80 92
34. H. Yamashita, T. Ito, H. Kato, S. Asai, H. Tanaka, and H. Nagai Comparison of the efficacy of tacrolimus and cyclosporine A in a murine model of dinitrofluorobenzene-induced atopic dermatitis European Journal of Pharmacology 645 2010 171 176