The Objective Severity Assessment of Atopic Dermatitis (OSAAD) score: Validity, reliability and sensitivity in adult patients with atopic dermatitis

British Journal of Dermatology

Volumn 153, Issue 4, 2005, Pages 767-773

  Angelova Fischer, I ^a   Bauer, A ^b   Hipler, U C ^b   Petrov, I ^a   Kazandjieva, J ^a   Bruckner, T ^c   Diepgen, T ^c   Tsankov, N ^a   Williams, M ^d   Fischer, T W ^b   Elsner, P ^b   Fluhr, Joachim W ^b  

^a MEDICAL UNIVERSITY OF SOFIA   (Bulgaria)

^b FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^c UNIVERSITY OF HEIDELBERG   (Germany)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Atopic dermatitis; OSAAD; Reliability; Severity score; Validity

Indexed keywords

INTERLEUKIN 16;

ADOLESCENT; ADULT; ARTICLE; ATOPIC DERMATITIS; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; HUMAN; MALE; MONITORING; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RELIABILITY; SENSITIVITY ANALYSIS; VALIDATION PROCESS;

ACUTE DISEASE; ADOLESCENT; ADULT; BIOLOGICAL MARKERS; DERMATITIS, ATOPIC; DIAGNOSIS, COMPUTER-ASSISTED; FEMALE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; INTERLEUKIN-16; MALE; OBSERVER VARIATION; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SEVERITY OF ILLNESS INDEX; WATER LOSS, INSENSIBLE;

EID: 26244451637     PISSN: 00070963     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2133.2005.06697.x     Document Type: Article

References (28)

1. Finlay A, Khan G. Dermatology Life Quality Index (DLQI): a simple practical measure for routine clinical use. Clin Exp Dermatol 1994; 19:210-16.
2. Eun H, Finlay A. Measurement of atopic dermatitis disability. Am Dermatol 1990; 2:9-12.
3. Gutgesell C, Heise S, Seubert A et al. Comparison of different activity parameters in atopic dermatitis: correlation with clinical scores. Br J Dermatol 2002; 147:914-19.
4. Wolkerstorfer A, Laan M, Savelkoul H et al. Soluble E-selectin, other markers of inflammation and disease severity in children with atopic dermatitis. Br J Dermatol 1998; 138:431-5.
5. Elsner P, Berardesca E, Maibach HI. Bioengineering of the Skin. Water and the Stratum Corneum. Boca Raton: CRC Press, 1994.
6. Fischer TW, Wigger-Alberti W, Elsner P. Assessment of 'dry skin': current bioengineering methods and test designs. Skin Pharmacol Appl Skin Physiol 2001; 14:183-95.
7. Charman C, Williams HC. Measuring atopic dermatitis severity in randomized controlled clinical trials: what exactly are we measuring? J Invest Dermatol 2003; 120:932-41.
8. Sugarman J, Fluhr J, Fowler A et al. The Objective Severity Assessment Atopic Dermatits Score. Arch Dermatol 2003; 139:1417-22.
9. Hanifin JM, Rajka G. Diagnostic features of atopic dermatitis. Acta Derm Venereal 1980; Suppl. 92:44-7.
10. Diepgen TL, Sauerbrei W, Fartasch M. Development and validation of diagnostic scores for atopic dermatitis incorporating criteria of data quality and practical usefulness. J Clin Epidemiol 1996; 49:1031-8.
11. Severity scoring of atopic dermatitis. the SCORAD index: consensus report of the European Task Force on Atopic Dermatitis. Dermatology 1993; 186:23-31.
12. Pinnagoda J, Tupker RA, Agner T et al. Guidelines for transepidermal water loss (TEWL) measurement: a report from the Standardization Group of the European Society of Contact Dermatitis. Contact Dermatitis 1990; 22:164-78.
13. Rogiers V. EEMCO guidance for the assessment of transepidermal water loss in cosmetic sciences. Skin Pharmacol Appl Skin Physiol 2001; 14:117-28.
14. Berardesca E. EEMCO guidance for assessment of stratum corneum hydration: electrical methods. Skin Res Technol 1997; 3:126-32.
15. Finlay A. Measurement of disease activity and outcome in atopic dermatitis. Br J Dermatol 1996; 135:509-15.
16. Charman C, Williams H. Outcome measures of disease severity in atopic dermatitis. Arch Dermatol 2000; 136:763-9.
17. Chamlin S, Kao J, Frieden I et al. Ceramide-dominant barrier repair lipids alleviate childhood atopic dermatitis: changes in barrier function provide a sensitive indicator of disease activity. J Am Acad Dermatol 2002; 47:198-208.
18. Seidenari S, Gusti G. Objective assessment of the skin of children affected by atopic dermatitis: a study of pH, capacitance and TEWL in eczematous and clinically uninvolved skin. Acta Derm Venereol 1995; 75:429-33.
19. Werner Linde Y. Dry skin in atopic dermatitis. Acta Derm Venereol 1992; 177:9-13.
20. Berardesca E, Fideli D, Borroni G et al. In vivo hydration and water-retention capacity of stratum corneum in clinically uninvolved skin in atopic and psoriatic patients. Acta Derm Venereol 1990; 70:400-4.
21. Aalto-Korte K. Improvement of skin barrier function during treatment of atopic dermatitis. J Am Acad Dermatol 1995; 33:969-72.
22. Eberlein-König B, Schäfer T, Huss-Marp J et al. Skin surface pH, stratum corneum hydration, trans-epidermal water loss and skin roughness related to atopic eczema and skin dryness in a population of primary school children. Acta Derm Venereol 2000; 80:188-91.
23. Frezzolini A, Paradisi M, Zaffiro A et al. Circulating interleukin 16 (IL-16) in children with atopic eczema/dermatitis syndrome (AEDS): a novel serological marker of disease activity. Allergy 2002; 57:815-20.
24. Masuda K, Katoh N, Okuda F, Kishimoto S. Increased levels of serum interleukin-16 in adult type atopic dermatitis. Acta Derm Venereol 2003; 83:249-53.
25. Kunz B, Oranje A, Labreze L et al. Clinical validation and guidelines for the SCORAD index: consensus report of the European Task Force on Atopic Dermatitis. Dermatology 1997; 195:10-19.
26. Schafer T, Dockery D, Kramer U et al. Experiences with severity scoring of atopic dermatitis in a population of German preschool children. Br J Dermatol 1997; 137:558-62.
27. Oranje A, Stalder J, Taieb A et al. Scoring of atopic dermatitis by SCORAD using a training atlas by investigators from different disciplines. Pediatr Allergy Immunol 1997; 8:28-34.
28. Charman C, Venn A, Williams H. Measurement of body surface area involvement in atopic eczema: an impossible task? Br J Dermatol 1999; 140:109-11.