The use of cyclosporine in dermatology: Part i

Journal of the American Academy of Dermatology

Volumn 63, Issue 6, 2010, Pages 925-946

  Amor, Karrie T ^a   Ryan, Caitriona ^b   Menter, Alan ^b  

^a UNIVERSITY OF TEXAS   (United States)

^b BAYLOR UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Atopic dermatitis; Chronic urticaria; Cyclosporine; Psoriasis; Pyoderma gangrenosum

Indexed keywords

ALPHA INTERFERON; AZATHIOPRINE; BETAMETHASONE DIPROPIONATE; BETAMETHASONE VALERATE; CAPSAICIN; CETIRIZINE; COLCHICINE; COLECALCIFEROL DERIVATIVE; CORTICOSTEROID; CYCLOPHOSPHAMIDE; CYCLOSPORIN; CYCLOSPORIN A; DAPSONE; ETRETIN; FUMARIC ACID; GOLD; ITRACONAZOLE; METHOTREXATE; METHYLPREDNISOLONE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; NONSTEROID ANTIINFLAMMATORY AGENT; PREDNISOLONE; PREDNISONE; RITUXIMAB; SALAZOSULFAPYRIDINE; SULFADIAZINE SILVER; TACROLIMUS; TRIAMCINOLONE ACETONIDE; TUMOR NECROSIS FACTOR INHIBITOR; UNINDEXED DRUG;

ABSENCE OF SIDE EFFECTS; ACRODERMATITIS CONTINUA; ALOPECIA; ALOPECIA AREATA; ALOPECIA TOTALIS; APHTHOUS ULCER; ASCITES; ATOPIC DERMATITIS; BEHCET DISEASE; CHRONIC URTICARIA; CLINICAL TRIAL; COMPETITIVE INHIBITION; CORTICOSTEROID THERAPY; CREATINE KINASE BLOOD LEVEL; CRYOTHERAPY; DERMATOMYOSITIS; DIARRHEA; DOSE RESPONSE; DRUG BIOAVAILABILITY; DRUG DOSE INCREASE; DRUG DOSE REDUCTION; DRUG DOSE REGIMEN; DRUG EFFICACY; DRUG INTERMITTENT THERAPY; DRUG MECHANISM; DRUG MEGADOSE; DRUG PULSE THERAPY; DRUG STRUCTURE; DRUG TOXICITY; DRUG TREATMENT FAILURE; EDEMA; EOSPINOPHILIC PUSTULAR FOLLICULITIS; EPIDERMOLYSIS BULLOSA ACQUISITA; ERYTHRODERMIC PSORIASIS; FOLLICULITIS; GENITAL ULCER; GRAFT REJECTION; HAILEY HAILEY DISEASE; HIRSUTISM; HUMAN; HYPERTENSION; IMMUNOSUPPRESSIVE TREATMENT; LICHEN PLANUS; LOW DRUG DOSE; MICROEMULSION; MONOTHERAPY; MOUTH ULCER; NEPHROTOXICITY; PANCREATITIS; PAPULAR SKIN DISEASE; PEMPHIGUS VULGARIS; PERIPHERAL NEUROPATHY; PHOTODERMATOSIS; PITYRIASIS RUBRA PILARIS; POMPHOLYX; PRESCRIPTION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PRURIGO NODULARIS; PSORIASIS; PSORIATIC ARTHRITIS; PUSTULOSIS PALMOPLANTARIS; PYODERMA GANGRENOSUM; QUALITY OF LIFE; REVIEW; RHEUMATOID ARTHRITIS; SCHNITZLER SYNDROME; SCLERODERMA; SIDE EFFECT; SKIN INFLAMMATION; SOLAR URTICARIA; SPLIT THICKNESS SKIN GRAFT; SUPPURATIVE HIDRADENITIS; TACHYPHYLAXIS; THERAPY EFFECT; TREATMENT DURATION; ULTRAVIOLET A RADIATION; ULTRAVIOLET B RADIATION; UNSPECIFIED SIDE EFFECT; URTICARIA;

CYCLOSPORINE; DERMATOLOGIC AGENTS; DERMATOLOGY; EDUCATION, MEDICAL, CONTINUING; HUMANS; SKIN DISEASES;

EID: 78649387833     PISSN: 01909622     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaad.2010.02.063     Document Type: Review

References (161)

1. J.F. Borel, C. Feuer, and H.U. Gubler Biological effects of cyclosporine A: a new anti-lymphocyte agent Agents Act 6 1976 468 475
2. R.Y. Calne, D.J. White, S. Thiru, D.B. Evans, P. McMaster, and D.C. Dunn Cyclosporin A in patients receiving renal allografts from cadaver donors Lancet 2 1978 1323 1327
3. W. Mueller, and B. Hermann Cyclosporin A for psoriasis N Engl J Med 301 1979 555
4. Cyclosporine (Neoral) product information 1997 Norvartis Pharmaceuticals Corporation New York
5. G.F. Ferraccioli, P. Tomietto, and M. De Santis Rationale for T cell inhibition by cyclosporine A in major autoimmune diseases Ann N Y Acad Sci 1051 2005 658 665
6. S.M. Stepkowski Molecular targets for existing and novel immunosuppressive drugs Expert Rev Mol Med 2 2000 1 23
7. T. Giese, M. Zeier, P. Schemmer, W. Uhl, M. Schoels, and T. Dengler Monitoring of NFAT-regulated gene expression in the peripheral blood of allograft recipients: a novel perspective toward individually optimized drug doses of cyclosporine A Transplantation 77 2004 339 344
8. A.K. Gupta, O. Baadsgaard, C.N. Ellis, J.J. Voorhees, and K.D. Cooper Lymphocytes and macrophages of the epidermis and dermis I nlesional psoriatic skin, but no epidermal Langerhans cells, are depleted by treatment with cyclosporine A Arch Dermatol Res 281 1989 219 226
9. S.L. Gottlieb, N.S. Heftler, P. Gilleaudeau, R. Johnson, V.P. Vallat, and J. Wolfe Short-contact anthralin treatment augments therapeutic efficacy of cyclosporine in psoriasis: a clinical and pathologic study J Am Acad Dermatol 33 1995 637 645
10. U. Mrowietz, and T. Ruzicka Cyclosporin A for psoriasis Dermatol Ther 11 1999 60 66
11. A. Menter, N.J. Korman, C.A. Elmets, S.R. Feldman, J.M. Gelfand, and K.B. Gordon Guidelines of care for the management of psoriasis and psoriatic arthritis: section 4. Guidelines of care for the management and treatment of psoriasis with traditional systemic agents J Am Acad Dermatol 61 2009 451 485
12. C.N. Ellis, D.C. Gorsulowsky, T.A. Hamilton, J.K. Billings, M.D. Brown, and J.T. Headington Cyclosporine improves psoriasis in a double-blind study JAMA 256 1986 3110 3116
13. C.E.M. Griffiths, A.V. Powles, J.N. Leonard, and L. Fry Clearance of psoriasis with low dose cyclosporine Br Med J 293 1986 731 732
14. C.N. Ellis, M.S. Fradin, J.M. Messana, M.D. Brown, M.T. Siegel, and A.H. Hartley Cyclosporine for plaque-type psoriasis. Results of a multidose, double-blind trial N Engl J Med 324 1991 277 284
15. P. Timonen, D. Friend, K. Abeywickrama, C. Laburte, B. Von Graffenried, and G. Feutren Efficacy of low-dose cyclosporine A in psoriasis: results of dose-finding studies Br J Dermatol 122 1990 33 39
16. E. Christophers, U. Mrowietz, H.H. Henneick, L. Färber, and D. Welzel Cyclosporine in psoriasis: a multicenter dose-finding study in severe plaque psoriaisis J Am Acad Dermatol 26 1992 86 90
17. G. Feutren, D. Friend, P. Timonen, and C. Laburte Cyclosporin monitoring in psoriasis Lancet 335 1990 866 867
18. L. Faerber, M. Braeutigam, G. Weidinger, U. Mrowietz, E. Christophers, and H.J. Schulze Cyclosporine in severe psoriasis: results of a meta-analysis in 579 patients Am J Clin Dermatol 2 2001 41 47
19. C.E. Griffiths, C.M. Clark, R.J. Chalmers, A. Li Wan Po, and H.C. Williams A systematic review of treatments for severe psoriasis Health Technol Assess 4 2000 1 125
20. C.E. Griffiths, L. Dubertret, C.N. Ellis, A.Y. Finlay, A.F. Finzi, and V.C. Ho Ciclosporin in psoriasis clinical practice: an international consensus statement Br J Dermatol 67 2004 11 23
21. C.E. Griffiths, A. Katsambas, B.A. Dijkmans, A.Y. Finlay, V.C. Ho, and A. Johnston Update on the use of ciclosporin in immune-mediated dermatoses Br J Dermatol 155 2006 1 16
22. S. Reitamo, P. Erkko, A. Remitz, A.I. Lauerma, O. Montonen, and K. Harjula Cyclosporine in the treatment of palmoplantar pustulosis: a randomized, double-blind, placebo-controlled study Arch Dermatol 129 1993 1273 1279
23. P. Erkko, H. Granlund, A. Remitz, K. Rosen, H. Mobacken, and B. Lindelöf Double-blind placebo-controlled study of long-term low-dose cyclosporine in the treatment of palmoplantar pustulosis Br J Dermatol 139 1998 997 1004
24. R.U. Peter, T. Ruzicka, G. Donhauser, and O. Braun-Falco Acrodermatitis continua-type of pustular psoriasis responds to low-dose cyclosporine J Am Acad Dermatol 23 1990 515 516
25. H. Zachariae, and K. Thestrup-Pedersen Ciclosporin A in acrodermatitis continua Dermatologica 175 1987 29 32
26. M. Lebwohl, C. Ellis, A. Gottlieb, J. Koo, G. Krueger, and K. Linden Cyclosporine consensus conference: with emphasis on the treatment of psoriasis J Am Acad Dermatol 39 1998 464 475
27. D. Pathirana, A.D. Ormerod, P. Saiag, C. Smith, P.I. Spuls, and A. Nast European S3-guidelines on the systemic treatment of psoriasis vulgaris J Eur Acad Dermatol Venereol 23 2009 1 70
28. J. Berth-Jones, C.A. Henderson, C.S. Munro, S. Rogers, R.J.G. Chalmers, and M.J. Boffa Treatment of psoriasis with intermittent short course cyclosporine (Neoral). A multicenter study Br J Dermatol 136 1997 527 530
29. V.C. Ho, C.E. Griffiths, G. Albrecht, F. Vanaclocha, G. León-Dorantes, and N. Atakan Intermittent short courses of cyclosporin (Neoral) for psoriasis unresponsive to topical therapy: a 1-year multicentre, randomized study. The PISCES Study Group Br J Dermatol 141 1999 283 291
30. V.C. Ho, C.E. Griffiths, J. Berth-Jones, K.A. Papp, F. Vanaclocha, and E. Dauden Intermittent short courses of cyclosporine microemulsion for the long-term management of psoriasis: a 2-year cohort study J Am Acad Dermatol 44 2001 643 651
31. E. Higgins, C. Munro, J. Marks, P.S. Friedmann, and S. Shuster Relapse rates in moderately severe chronic psoriasis treated with cyclosporine A Br J Dermatol 121 1989 71 74
32. M. Rosenbach, S. Hsu, N.J. Korman, M.G. Lebwohl, M. Young, and B.F. Bebo Jr. Treatment of erythrodermic psoriasis: from the medical board of the National Psoriasis Foundation J Am Acad Deramtol 62 2010 655 662
33. C.E.M. Griffiths, A.V. Powles, J. McFadden, B.S. Baker, H. Valdimarsson, and L. Fry Long term cyclosporine for psoriasis Br J Dermatol 120 1989 256 266
34. C. Laburte, R. Grossman, J. Abi-Rached, K.H. Abeywickrama, and L. Dubertret Efficacy and safety of oral cyclosporine in psoriasis Br J Dermatol 130 1994 366 375
35. A.V. Powles, B.S. Baker, H. Valdimarsson, B. Hulme, and L. Fry Four years of experience with cyclosporin in psoriasis Br J Dermatol 122 suppl 36 1990 13 19
36. A. Ozawa, J. Sugai, M. Ohkido, M. Ohtsuki, H. Nakagawa, and H. Kitahara Cyclosporin in psoriasis: continuous monotherapy versus intermittent long-term therapy Eur J Dermatol 9 1999 218 223
37. G.C. Chaidemenos, O. Mourellou, N. Avgoustinaki, M. Papakonstantinou, G. Karakatsanis, and A. Katsambas Intermittent vs. continuous 1-year cyclosporin use in chronic plaque psoriasis J Eur Acad Dermatol Venereol 21 2007 1203 1208
38. J. Shupack, E. Abel, E. Bauer, M. Brown, L. Drake, and R. Freinkel Cyclosporine as maintenance therapy in patients with severe psoriasis J Am Acad Dermatol 36 1997 423 432
39. C.N. Ellis, M.S. Fradin, T.A. Hamilton, and J.J. Voorhees Duration of remission during maintenance cylcosporine therapy for psoriasis: relationship to maintenance dose and degree of improvement during initial therapy Arch Dermatol 131 1995 791 795
40. R.M. Grossman, J. Thivolet, A. Claudy, P. Souteyrand, J.J. Guilhou, and P. Thomas A novel therapeutic approach to psoriasis with combination calcipotriol ointment and very low-dose cyclosporine: results of a multicenter placebo-controlled study J Am Acad Dermatol 31 1994 68 74
41. M. Ameen, H.R. Smith, and J.N. Barker Combined mycophenolate mofetil and cyclosporin therapy for severe recalcitrant psoriasis Clin Exp Dermatol 26 2001 480 483
42. P. Balasubramaniam, O. Stevenson, and J. Berth-Jones Fumaric acid esters in severe psoriasis, including experience of use in combination with other systemic modalities Br J Dermatol 150 2004 741 746
43. H.H. Roenigk Acitretin combination therapy J Am Acad Dermatol 41 3 pt 2 1999 S18 S21
44. C.M. Clark, B. Kirby, A.D. Morris, S. Davison, I. Zaki, and R. Emerson Combination treatment with methotrexate and cyclosporine for severe recalcitrant psoriasis Br J Dermatol 141 1999 279 282
45. A.L. Kuijpers, R.J. Van Dooren-Geebe, and P.C. van de Kerkhof Failure of combination therapy with acitretin and cyclosporin A in 3 patients with erythrodermic psoriasis Dermatology 194 1997 88 90
46. G.D. Weinstein, and G.M. White An approach to the treatment of moderate to severe psoriasis with rotational therapy J Am Acad Dermatol 28 1993 454 459
47. M.A. de Rie, M.M. Meinardi, and D. Bos Analysis of side-effects of medium- and low-dose cyclosporine maintenance therapy in psoriasis Br J Dermatol 123 1990 347 353
48. N.J. Levell, S. Schuster, C.S. Munro, and P.S. Friedmann Remission of ordinary psoriasis following a short clearance course of cyclosporine Acta Derm Venereol 75 1995 65 69
49. A.D. Fraser, A.W. van Kuijk, R. Westhovens, Z. Karim, R. Wakefield, and A.H. Gerards A randomized, double blind, placebo controlled, multicentre trial of combination therapy with methotrexate plus ciclosporin in patients with active psoriatic arthritis Ann Rheum Dis 64 2005 859 864
50. A.K. Gupta, E.L. Matteson, C.N. Ellis, V.C. Ho, D.C. Tellner, and J.J. Voorhees Cyclosporine in the treatment of psoriatic arthritis Arch Dermatol 125 1989 507 510
51. K. Steinsson, I. Jónsdóttir, and H. Valdimarsson Cyclosporin A in psoriatic arthritis: an open study Ann Rheum Dis 49 1990 603 606
52. C. Salvarani, P. Macchioni, L. Boiardi, F. Rossi, M. Casadei Maldini, and R. Mancini Low dose cyclosporine A in psoriatic arthritis: relation between soluble interleukin 2 receptors and response to therapy J Rheumatol 19 1992 74 79
53. G. Mahrle, H.J. Schulze, M. Bräutigam, P. Mischer, R. Schopf, and E.G. Jung Anti-inflammatory efficacy of low-dose cyclosporine A in psoriatic arthritis. A prospective multicentre study Br J Dermatol 135 1996 752 757
54. A. Spadaro, V. Riccieri, A. Sili-Scavalli, F. Sensi, E. Taccari, and A. Zoppini Comparison of cyclosporine A and methotrexate in the treatment of psoriatic arthritis: a one-year prospective study Clin Exp Rheumatol 13 1995 589 593
55. C. BuBmann, T. Bieber, and N. Novak Systemic therapeutic options for severe atopic dermatitis J Dtsch Dermatol Ges 7 2009 205 219
56. J.M. Hanifin, K.D. Cooper, V.C. Ho, S. Kang, B.R. Krafchik, and D.J. Margolis Guidelines of care for atopic dermatitis J Am Acad Dermatol 50 2004 391 404
57. J. Schmitt, K. Schakel, N. Schmitt, and M. Meurer Systemic treatment of severe atopic eczema: a systematic review Acta Derm Venereol 87 2007 100 111
58. J.I. Harper, J. Berth-Jones, R.D. Camp, M.J. Dillon, A.Y. Finlay, and C.A. Holden Cyclosporin for atopic dermatitis in children Dermatology 203 2001 3 6
59. J.M. Sowden, J. Berth-Jones, J.S. Ross, R.J. Motley, R. Mark, and A.Y. Finlay A multicentre, double-blind, placebo controlled crossover study to assess the efficacy and safety of cyclosporine in adult patients with severe refractory atopic dermatitis Lancet 338 1991 337 340
60. R.D. Camp, S. Reitamo, P.S. Friedmann, V. Ho, and F. Heule Cyclosporin A in severe, therapy-resistant atopic dermatitis: report of an international workshop, April 1993 Br J Dermatol 129 1993 217 220
61. J. Schmitt, N. Schmitt, and M. Meurer Cyclosporin in the treatment of patients with atopic eczema - a systematic review and meta-analysis J Eur Acad Dermatol Venereol 21 2007 606 619
62. J.I. Harper, I. Ahmed, G. Barclay, M. Lacour, P. Hoeger, and M.J. Cork Cyclosporin for severe childhood atopic dermatitis: short course versus continuous therapy Br J Dermatol 142 2000 52 58
63. I.M. Zonneveld, M.A. de Rie, R.C. Beljaards, H.J. Van Der Rhee, J. Wuite, and J. Zeegelaar The long-term safety and efficacy of cyclosporine in severe refractory atopic dermatitis: a comparison of two dosage regimens Br J Dermatol 135 1996 15 20
64. C.S. Munro, N.J. Levell, S. Shuster, and P.S. Friedmann Maintenance treatment with ciclosporin in atopic eczema Br J Dermatol 130 1994 376 380
65. H. Granlund, P. Erkko, M. Sinisalo, and S. Reitamo Cyclosporin in atopic dermatitis: time to relapse and effect of intermittent therapy Br J Dermatol 132 1995 106 112
66. N. Atakan, and C. Erdem The efficacy, tolerability and safety of a new oral formulation of Sandimmun - Sandimmun Neoral in severe refractory atopic dermatitis J Eur Acad Dermatol Venereol 11 1998 240 246
67. N. Sepp, and P.O. Fritsch Can cyclosporine A induce permanent remission of atopic dermatitis? Br J Dermatol 128 1993 213 216
68. J. Berth-Jones, R.A.C. Graham-Brown, R. Marks, R.D.R. Camp, J.S.C. English, and K. Freeman Long-term efficacy and safety of cyclosporine in severe, adult atopic dermatitis Br J Dermatol 136 1997 76 81
69. M.S. Salek, A.Y. Finlay, D.K. Luscombe, B.R. Allen, J. Berth-Jones, and R.D. Camp Cyclosporin greatly improves the quality of life in adults with severe atopic dermatitis. A randomized, double-blind, placebo-controlled trial Br J Dermatol 129 1993 422 430
70. J.M. Naeyaert, J.M. Lachapelle, H. Degreef, M. de la Brassinne, M. Heenen, and J. Lambert Cyclosporin in atopic dermatitis: review of the literature and outline of a Belgian consensus Dermatology 198 1999 145 152
71. D.J. Hijnen, O. ten Berge, L. Timmer-de Mik, C.A. Bruijzeel-Koomen, and M.S. de Bruin-Weller Efficacy and safety of long-term treatment with cyclosporine A for atopic dermatitis J Eur Acad Dermatol Venereol 21 2007 85 89
72. D.J. Hijnen, E. Knol, C. Bruijnzeel-Koomen, and M. de Bruin-Weller Cyclosporin A treatment is associated with increased serum immunoglobulin E levels in a subgroup of atopic dermatitis patients Dermatitis 18 2007 163 165
73. J. Reichrath, G. Bens, A. Bonowitz, and W. Tilgen Treatment recommendations for pyoderma gangrenosum: an evidence-based review of the literature based on more than 350 patients J Am Acad Dermatol 53 2005 273 283
74. R.K. Chow, and V.C. Ho Treatment of pyoderma gangrenosum J Am Acad Dermatol 34 1996 1047 1060
75. M.A. McAleer, F.C. Powell, D. Devaney, and B.F. O'Donnell Infantile pyoderma gangrenosum J Am Acad Dermatol 58 2 suppl 2008 S23 S28
76. A. Reich, and J. Maj Cisło M, Szepietowski JC. Periungual lesions in pyoderma gangrenosum Clin Exp Dermatol 34 2009 e81 e84
77. Y. Takahashi, Y. Yamaguchi, K. Itoh, S. Sano, A. Morita, and I. Katayama Intractable wounds caused by pyoderma gangrenosum in a patient with critical limb ischemia treated with cyclosporine and adjuvant sympathectomy Dermatol Surg 35 2009 699 703
78. A. Duncan, A. Bharati, J. Wu, P. Currie, and S.I. White Pyoderma gangrenosum folllowing pacemaker insertion Clin Exp Dermatol 34 2009 444 445
79. C.S. Petersen, and T. Menné Cyclosporin A responsive chronic severe vesicular hand eczema Acta Derm Venereol 72 1992 436 437
80. S. Reitamo, and H. Granlund Cyclosporin A in the treatment of chronic dermatitis of the hands Br J Dermatol 130 1994 75 78
81. H. Granlund, P. Erkko, E. Eriksson, and S. Reitamo Comparison of cyclosporine and topical betamethasone-17,21-dipropionate in the treatment of severe chronic hand eczema Acta Derm Venereol 76 1996 371 376
82. C.E. Grattan, and F. Humphreys British Association of Dermatologists Therapy Guidelines and Audit Subcommittee. Guidelines for evaluation and management of urticaria in adults and children Br J Dermatol 157 2007 1116 1123
83. A.P. Kaplan Chronic urticaria: pathogenesis and treatment J Allergy Clin Immunol 114 2004 465 474
84. A.P. Kaplan What the first 10,000 patients with chronic uriticaria have taught me: a personal journey J Allergy Clin Immunol 123 2009 713 717
85. H. Serhat Inaloz, S. Ozturk, C. Akcali, N. Kirtak, and M. Tarakcioglu Low-dose and short-term cyclosporine treatment in patients with chronic idiopathic urticaria: a clinical and immunological evaluation J Dermatol 35 2008 276 282
86. G.A. Vena, N. Cassano, D. Colombo, E. Peruzzi, and P. Pigatto Neo-I-30 Study Group. Cyclosporine in chronic idiopathic urticaria: a double-blind, randomized, placebo-controlled trial J Am Acad Dermatol 55 2006 705 709
87. E.B. Baskan, S. Tunali, T. Turker, and H. Saricaoglu Comparison of short-and long-term cyclosporine A therapy in chronic idiopathic urticaria J Dermatolog Treat 15 2004 164 168
88. A. Kessel, and E. Toubi Extended cyclosporine A- treatment for severe chronic urticaria Harefuah 145 2006 411 414 471
89. M. Di Gioacchino, F. Di Stefano, E. Cavallucci, N. Verna, S. Ramondo, and F. Paolini Treatment of chronic idiopathic uriticaria and positive autologous serum skin test with cyclosporine: clinical and immunological evaluation Allergy Asthma Proc 24 2003 285 290
90. K. Giuliodori, G. Ganzetti, A. Campanati, O. Simonetti, B. Marconi, and A. Offidani A non-responsive chronic autoimmune urticaria in a 12-year-old autistic girl treated with cyclosporin J Eur Acad Dermatol Venereol 23 2009 619 620
91. J. Carbone, A. Paravisini, E. Sarmiento, J. Rodríguez-Molina, and E. Fernández-Cruz Partial response to cyclosporine in a patient with Schnizler's syndrome Allergol Immunopathol (Madr) 35 2007 71 73
92. M. Pascual-López, A. Hernández-Núñez, J. Sánchez-Pérez, J. Fernández-Herrera, and A. García-Díez Schinitzler's syndrome with monoclondal IgG kappa gammopathy: good response to cyclosporin J Eur Acad Dermatol Venereol 16 2002 267 270
93. P.A. Galindo Bonilla, J. Borja Segade, E. Gómez Torrijos, and F. Feo Brito Urticaria and cyclosporine Allergy 57 2002 650 651
94. D. Mendes, M. Correia, M. Barbedo, T. Vaio, M. Mota, and O. Gonalves Behet's disease - a contemporary review J Autoimmun 32 2009 178 188
95. I. Kötter, I. Günaydin, M. Batra, R. Vonthein, N. Stübiger, and G. Fierlbeck CNS involvement occurs more frequently in patients with Behet's disease under cyclosporine A (CSA) than under other medications: results of a retrospective analysis of 117 cases Clin Rheumatol 25 2006 482 486
96. K. Masuda, A. Nakajima, A. Urayama, K. Nakae, M. Kogure, and G. Inaba Double-masked trial of cyclosporin versus colchicine and long-term open study of cyclosporine in Behet's disease Lancet 1 1989 1093 1095
97. P. Lin, and G. Liang Behet disease: recommendation for clinical management of mucocutaneous lesions J Clin Rheumatol 12 2006 282 286
98. O. Avci, N. Gürler, and A.T. Güne Efficacy of cyclosporine on mucocutaneous manifestations of Behet's disease J Am Acad Dermatol 36 1997 796 797
99. R.M. Torres, B. Yáñez, J.M. Herreras, and M. Calonge Ocular Behet disease. Retrospective study Arch Soc Esp Oftalmol 79 2004 599 603
100. P.C. Ozdal, S. Orta, I. Taskintuna, and E. Firat Long-term therapy with low dose cyclosporine A in ocular Behet's disease Doc Ophthalmol 105 2002 301 312
101. A. Vikas, S. Atul, R. Singh, L. Sarbmeet, and H. Mohan Behet's disease with replapsing cutaneous polyarteritis-nodosa-like lesions, responsive to oral cyclosporine therapy Dermatol Online J 9 2003 9
102. I. Kötter, I. Günaydin, M. Batra, R. Vonthein, N. Stübiger, and G. Fierlbeck CNS involvement occurs more frequently in patients with Behet's disease under cyclosporine A (CSA) than under other medications- results of a retrospective analysis of 117 cases Clin Rheumatol 25 2006 482 486
103. C.H. Dicken Treatment of classic pityriasis rubra pilaris J Am Acad Dermatol 31 1994 997 999
104. K. Usuki, M. Sekiyama, T. Shimada, S. Shimada, and T. Kanzaki Three cases of pityriasis rubra pilaris successfully treated with cyclosporin A Dermatology 200 2000 324 327
105. T. Wetzig, and M. Sticherling Juvenile pityriasis rubra pilaris: successful treatment with ciclosporin Br J Dermatol 149 2003 202 203
106. S.R. Ytterberg Treatment of refractory polymyositis and dermatomyositis Curr Rheumatol Rep 8 2006 167 173
107. L.J. Iorizzo 3rd, and J.L. Jorizzo The treatment and prognosis of dermatomyositis: an updated review J Am Acad Dermatol 59 2008 99 112
108. A.C. Cordeiro, and D.A. Isenberg Treatment of inflammatory myopathies Postgrad Med J 82 2006 417 424
109. K. Maeda, R. Kimura, K. Komuta, and T. Igarashi Cyclosporine treatment for polymyositis/dermatomyositis: is it possible to rescue the deteriorating cases with interstitial pneumonitis? Scand J Rheumatol 2 1997 24 29
110. S. Mii, S. Niiyama, M. Kusunoki, S. Arai, and K. Katsuoka Cyclosporine A as treatment of esophageal involvement in dermatmyositis Rheumatol Int 27 2006 183 185
111. M. Terao, K. Ozawa, S. Inui, H. Murota, A. Yokomi, and S. Itami A case of dermatomyositis complicated with pneumomediastinum Mod Rheumatol 17 2007 156 159
112. T. Kotani, S. Makino, T. Takeuchi, M. Kagitani, T. Shoda, and A. Hata Early intervention with corticosteroids and cyclosporine A and 2-hour post dose blood concentration monitoring improves the prognosis of acute/subacute interstitial pneumonia in dermatomyositis J Rheumatol 35 2008 254 259
113. K. Takada, K. Nagasaka, and N. Miyasaka Polymyositis/dermatomyositis and interstitial lung disease: a new therapeutic approach with T-cell-specific immunosuppressants Autoimmunity 38 2005 383 392
114. E. Schmidt, M. Goebeler, and D. Zillikens Rituximab in severe pemphigus Ann N Y Acad Sci 1173 2009 683 691
115. N. Mobini, T. Padilla Jr., and A.R. Ahmed Long-term remission in selected patients with pemphigus vulgaris treated with cyclosporine J Am Acad Dermatol 36 1997 264 266
116. K.E. Harman, S. Albert, and M.M. Black Guidelines for the management of pemphigus vulgaris Br J Dermatol 149 2003 926 937
117. M. Lapidoth, M. David, D. Ben-Amitai, V. Katzenelson, S. Lustig, and M. Sandbank The efficacy of combined treatment with prednisone and cyclosporine in patients with pemphigus: a preliminary study J Am Acad Dermatol 30 1994 752 757
118. H. Barthelemy, A. Frappaz, F. Cambazard, G. Mauduit, B. Rouchouse, and J. Kanitakis Treatment of nine cases of pemphigus vulgaris with cyclosporine J Am Acad Dermatol 18 1988 1262 1266
119. D. Pathirana, A.D. Ormerod, P. Saiag, C. Smith, P.I. Spuls, and A. Nast European S3-Guidelines on the systemic treatment of psoriasis vulgaris J Eur Acad Dermatol Venereol 23 2009 5 70
120. D. Ioannides, F. Chrysomallis, and J.C. Bystryn Ineffectiveness of cyclosporine as an adjuvant to corticosteroids in the treatment of pemphigus Arch Dermatol 136 2000 868 872
121. M. Olszewska, Z. Kolacinska-Strasz, J. Sulej, H. Labecka, J. Cwikla, and U. Natorska Efficacy and safety of cyclophsphamide, azathioprine, and cyclosporine (ciclosporin) as adjuvant drugs in pemphigus vulgaris Am J Clin Dermatol 8 2007 85 92
122. L. Engineer, and A.R. Ahmed Emerging treatment for epidermolysis bullosa acquisita J Am Acad Dermatol 44 2001 818 828
123. M.L. Khatri, M. Benghazeil, and M. Shafi Epidermolysis bullosa acquisita responsive to cyclosporine therapy J Eur Acad Dermatol Venereol 15 2001 182 184
124. J.C. Maize Jr., and J.B. Cohen Cyclosporine controls epidermolysis bullosa acquisita co-occurring with acquired factor VII deficiency Int J Dermatol 44 2005 692 694
125. G. Stinco, R. Codutti, A. Frattasio, V. De Francesco, and P. Patrone Chronic actinic dermatitis treated with cyclosporine-A Eur J Dermatol 12 2002 455 457
126. P. Paquet, and G.E. Piérard Severe chronic actinic dermatitis treated with cyclosporine: 2 cases Ann Dermatol Venereol 128 2001 42 45
127. D.R. Shipley, and J.B. Hewitt Polymorphic light eruption treated with cyclosporin Br J Dermatol 144 2001 446 447
128. O. Lasa, I. Trebol, J. Gardeazabal, and J.L. Diaz-Perez Prophylactic short-term use of cyclosporine in refactory polymorphic light eruption J Eur Acad Dermatol Venereol 18 2004 747 748
129. D.W. Edström, and A.M. Ros Cyclosporin A therapy for severe solar urticaria Photodermatol Photoimmunol Photomed 13 1997 61 63
130. V.C. Ho, A.K. Gupta, C.N. Ellis, B.J. Nickoloff, and J.J. Voorhees Treatment of severe lichen planus with cyclosporine J Am Acad Dermatol 22 1990 64 68
131. P.D. Pigatto, G. Chiappino, A. Bigardi, N. Mozzanica, and A.F. Finzi Cyclosporin A for the treatment of severe lichen planus Br J Dermatol 122 1990 121 123
132. N.J. Levell, C.S. Munro, and J.M. Marks Severe lichen planus clears with very low-dose cyclosporine Br J Dermatol 127 1992 66 67
133. B. Cribier, C. Frances, and O. Chosidow Treatment of lichen planus: an evidence-based medicine analysis of efficacy Arch Dermatol 134 1998 1521 1530
134. C. Schepis, M. Siragusa, and M. Lentini Erosive lichen planus: two uncommon cases Acta Derm Venereol 88 2008 268 270
135. P. Patrone, G. Stinco, E. La Pia, A. Frattasio, and V. De Francesco Surgery and cyclosporine A in the treatment of erosive lichen planus of the feet Eur J Dermatol 8 1998 243 244
136. R. Laeijendecker, T. Van Joost, B. Tank, A.P. Oranje, and H.A. Neumann Oral lichen planus in childhood Pediatr Dermatol 22 2005 299-30
137. G. Karakatsanis, A. Patsatsi, C. Kastoridou, and D. Sotiriadis Palmoplantar lichen planus with umbilicated papules: an atypical case with rapid therapeutic response to cyclosporin J Eur Acad Dermatol Venereol 21 2007 1006 1007
138. L. Gallo, F. Ayala, and F. Ayala Relapsing lichen actinicus successfully treated with cyclosporine J Eur Acad Dermatol Venereol 22 2008 370 371
139. T.K. Lane, H. Kamino, R.F. Walters, S. Meehan, and M.K. Pomeranz Lichen planopilaris and psoriasis Dermatol Online J 14 2008 4
140. P. Mirmirani, A. Willey, and V.H. Price Short course of oral cyclosporine in lichen planopilaris J Am Acad Dermatol 49 2003 667 671
141. L. Bianchi, A. Paro Vidolin, P. Piemonte, I. Carboni, and S. Chimenti Graham Little-Piccardi-Lassueur syndrome: effective treatment with cyclosporine A Clin Exp Dermatol 26 2001 518 520
142. M.R. Lee, and S. Shumack Prurigo nodularis: a review Australas J Dermatol 46 2005 211 218
143. D. Siepmann, T.A. Luger, and S. Ständer Antipruritc effect of cyclosporine microemulsion in prurigo noduaris: results of case series J Dtsch Dermatol Ges 6 2008 941 946
144. A.K. Gupta, C.N. Ellis, K.D. Cooper, B.J. Nickoloff, V.C. Ho, and L.S. Chan Oral cyclosporine for the treatment of alopecia areata J Am Acad Dermatol 22 1990 242 250
145. S.P. McDonald Hull, M.L. Wood, P.E. Hutchinson, and P.E. Sladden Guidelines for the management of alopecia areata Br J Dermatol 149 2003 692 699
146. J. Ferrando, and R. Grimalt Partial response of severe alopecia areata to cyclosporine A Dermatology 199 1999 67 69
147. B.J. Kim, S.U. Min, K.Y. Park, J.W. Choi, S.W. Park, and S.W. Youn Combination therapy of cyclosporine and methylprednisolone on severe alopecia areata J Dermatolog Treat 19 2008 216 220
148. M. Shaheedi-Dadras, A. Karami, F. Mollaei, H. Moravvej, and F. Malekzad The effect of methylprednisolone pulse-therapy plus oral cyclosporine in the treatment of alopecia totalis and universalis Arch Iran Med 11 2008 90 93
149. J. Shapiro, H. Lui, V. Tron, and V. Ho Systemic cyclosporine and low-dose prednisone in the treatment of chronic severe alopecia areata: a clinical and immunopathologic evaluation J Am Acad Dermatol 36 1997 114 117
150. C. Schepis, and C. Barone Lazzaro Danzuso GC, Romano C. Alopecia areata in Down syndrome: a clinical evaluation J Eur Acad Dermatol Venereol 19 2005 769 770
151. M.A. Phillips, J.E. Graves, and J.R. Nunley Alopecia areata presenting in 2 kidney-pancreas transplant recipients taking cyclosporine J Am Acad Dermatol 53 5 suppl. 1 2005 S252 S255
152. J.C. Moreno, M.S. Ocaña, and A. Vélez Cyclosporin A and alopecia areata J Eur Acad Dermatol Venereol 16 2002 417 418
153. N. Usmani, and C. Wilson A novel treatment for recalcitrant benign familial pemphigus J Eur Acad Dermatol Venereol 21 2007 264 266
154. J. Berth-Jones, S.G. Smith, and R.A. Graham-Brown Benign familial chronic pemphigus (Hailey-Hailey disease) responds to cyclosporin Clin Exp Dermatol 20 1995 70 72
155. E. Ellis, and N. Scheinfeld Eosinophilic pustular folliculitis: a comprehensive review of treatment options Am J Clin Dermatol 5 2004 189 197
156. S. Fukamachi, K. Kabashima, K. Sugita, M. Kobayashi, and Y. Tokura Therapeutic effectiveness of various treatments for eosinophilic pustular folliculitis Acta Derm Venereol 89 2009 155 159
157. D.A. Buckley, and S. Rogers Cyclosporin-responsive hidradenitis suppurativa J R Soc Med 88 1995 289 290
158. R.F. Rose, M.J. Goodfield, and S.M. Clark Treatment of recalcitrant hidradenitis suppurativa with oral ciclosporin Clin Exp Dermatol 31 2006 154 155
159. S.J. Morton, and R.J. Powell Cylcosporin and tacrolimus: their use in a routine clinical setting for scleroderma Rheumatology 39 2000 865 869
160. H. Zachariae, L. Halkier-Sørensen, L. Heickendorff, E. Zachariae, and H.E. Hansen Cyclosporin treatment of systemic sclerosis Br J Dermatol 122 1990 677 681
161. O. Kowal-Bielecka, R. Landewé, J. Avouac, S. Chwiesko, I. Miniati, and L. Czirjak EULAR recommendations for the treatment of systemic sclerosis: a report from the EULAR Scleroderma Trials and Research group (EUSTAR) Ann Rheum Dis 68 2009 620 628