ROS Production Is Essential for the Apoptotic Function of E2F1 in Pheochromocytoma and Neuroblastoma Cell Lines

PLoS ONE

Volumn 7, Issue 12, 2012, Pages

  Espada, Lilia ^a   Meo Evoli, Nathalie ^a,b   Sancho, Patricia ^b   Real, Sebastian ^a   Fabregat, Isabel ^a,b   Ambrosio, Santiago ^a   Tauler, Albert ^a,b  

^a UNIVERSITY OF BARCELONA   (Spain)

^b BELLVITGE BIOMEDICAL RESEARCH INSTITUTE IDIBELL   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; AFIMOXIFENE; CASPASE 3; CASPASE 8; CELL PROTEIN; FLICE INHIBITORY PROTEIN; GLYCOGEN SYNTHASE KINASE 3BETA; PROTEIN BAX; PROTEIN BCL XL; PROTEIN BIML; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR E2F1; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL NUCLEUS; CELL STRAIN SH SY5Y; CELL STRAIN SK N JD; CONTROLLED STUDY; CYTOSOL; DOWN REGULATION; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INHIBITION; GENE ACTIVATION; GENE EXPRESSION PROFILING; GENE TARGETING; GENETIC TRANSCRIPTION; INTRACELLULAR TRANSPORT; MITOCHONDRION; NEUROBLASTOMA CELL; NONHUMAN; OXIDATIVE STRESS; PHEOCHROMOCYTOMA CELL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; RAT; SIGNAL TRANSDUCTION;

ADRENAL GLAND NEOPLASMS; ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BCL-X PROTEIN; CASP8 AND FADD-LIKE APOPTOSIS REGULATING PROTEIN; CELL LINE, TUMOR; E2F1 TRANSCRIPTION FACTOR; HUMANS; MITOCHONDRIA; NEUROBLASTOMA; PHEOCHROMOCYTOMA; PROTEIN MULTIMERIZATION; PROTEIN TRANSPORT; RATS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EID: 84871237301     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0051544     Document Type: Article

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