The ciliary EVC/EVC2 complex interacts with smo and controls hedgehog pathway activity in chondrocytes by regulating Sufu/Gli3 dissociation and Gli3 trafficking in primary cilia

Human Molecular Genetics

Volumn 22, Issue 1, 2013, Pages 124-139

  Caparrós Martín, Jose A ^a,b   Valencia, María ^a   Reytor, Edel ^a,b   Pacheco, María ^a   Fernandez, Margarita ^a   Perez Aytes, Antonio ^c   Gean, Esther ^d   Lapunzina, Pablo ^b,e   Peters, Heiko ^f   Goodship, Judith A ^f   Ruiz Perez, Victor L ^a,b  

^a CSIC   (Spain)

^b INSTITUTO DE SALUD CARLOS III   (Spain)

^c HOSPITAL UNIVERSITARIO LA FE   (Spain)

^d HOSPITAL SANT JOAN DE DÉU   (Spain)

^e HOSPITAL UNIVERSITARIO LA PAZ IDIPAZ   (Spain)

^f NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GALACTOSIDASE; PROTEIN EVC; PROTEIN EVC2; PROTEIN PATCHED 1; SMOOTHENED PROTEIN; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR GLI3; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARTILAGE CELL; CELL DIFFERENTIATION; CELL MIGRATION; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CILIATED EPITHELIUM; CONTROLLED STUDY; DYSOSTOSIS; EMBRYO; ENCHONDRAL OSSIFICATION; ENZYME ACTIVITY; EUKARYOTIC FLAGELLUM; GENE MUTATION; GENE SILENCING; HOMOZYGOSITY; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

ANIMALS; CHONDROCYTES; CILIA; HEDGEHOG PROTEINS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MEMBRANE PROTEINS; MICE; MICE, MUTANT STRAINS; NERVE TISSUE PROTEINS; PROTEIN TRANSPORT; RECEPTORS, G-PROTEIN-COUPLED; REPRESSOR PROTEINS;

ERINACEIDAE; MAMMALIA; MUS;

EID: 84871229068     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/dds409     Document Type: Article

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