메뉴 건너뛰기




Volumn 194, Issue 12, 2012, Pages 977-989

FliA expression analysis and influence of the regulatory proteins RpoN, FleQ and FliA on virulence and in vivo fitness in Legionella pneumophila

Author keywords

Corby; Flagellin regulation; FleQ; FliA; In vivo fitness; Legionella pneumophila; Paris; RpoN; Straight hook; Virulence

Indexed keywords

MESSENGER RNA; PROTEIN FLEQ; PROTEIN FLIA; REGULATOR PROTEIN; SIGMA FACTOR RPON; UNCLASSIFIED DRUG;

EID: 84871212092     PISSN: 03028933     EISSN: 1432072X     Source Type: Journal    
DOI: 10.1007/s00203-012-0833-y     Document Type: Article
Times cited : (20)

References (55)
  • 1
    • 73649119529 scopus 로고    scopus 로고
    • Control of flagellar gene regulation in Legionella pneumophila and its relation to growth phase
    • Albert-Weissenberger C, Sahr T, Sismeiro O, Hacker J, Heuner K, Buchrieser C (2010) Control of flagellar gene regulation in Legionella pneumophila and its relation to growth phase. J Bacteriol 192(2):446-455
    • (2010) J Bacteriol , vol.192 , Issue.2 , pp. 446-455
    • Albert-Weissenberger, C.1    Sahr, T.2    Sismeiro, O.3    Hacker, J.4    Heuner, K.5    Buchrieser, C.6
  • 2
    • 0034968828 scopus 로고    scopus 로고
    • RpoS co-operates with other factors to induce Legionella pneumophila virulence in the stationary phase
    • DOI 10.1046/j.1365-2958.2001.02465.x
    • Bachman MA, Swanson MS (2001) RpoS co-operates with other factors to induce Legionella pneumophila virulence in the stationary phase. Mol Microbiol 40(5):1201-1214 (Pubitemid 32574986)
    • (2001) Molecular Microbiology , vol.40 , Issue.5 , pp. 1201-1214
    • Bachman, M.A.1    Swanson, M.S.2
  • 3
    • 2142810201 scopus 로고    scopus 로고
    • Genetic Evidence that Legionella pneumophila RpoS Modulates Expression of the Transmission Phenotype in Both the Exponential Phase and the Stationary Phase
    • DOI 10.1128/IAI.72.5.2468-2476.2004
    • Bachman MA, Swanson MS (2004) Genetic evidence that Legionella pneumophila RpoS modulates expression of the transmission phenotype in both the exponential phase and the stationary phase. Infect Immun 72(5):2468-2476 (Pubitemid 38542371)
    • (2004) Infection and Immunity , vol.72 , Issue.5 , pp. 2468-2476
    • Bachman, M.A.1    Swanson, M.S.2
  • 4
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 6
    • 0031841662 scopus 로고    scopus 로고
    • Expression of Legionella pneumophila virulence traits in response to growth conditions
    • Byrne B, Swanson MS (1998) Expression of Legionella pneumophila virulence traits in response to growth conditions. Infect Immun 66(7):3029-3034 (Pubitemid 28303093)
    • (1998) Infection and Immunity , vol.66 , Issue.7 , pp. 3029-3034
    • Byrne, B.1    Swanson, M.S.2
  • 8
    • 58449098832 scopus 로고    scopus 로고
    • SpoT governs Legionella pneumophila differentiation in host macrophages
    • Dalebroux ZD, Edwards RL, Swanson MS (2009) SpoT governs Legionella pneumophila differentiation in host macrophages. Mol Microbiol 71(3):640-658
    • (2009) Mol Microbiol , vol.71 , Issue.3 , pp. 640-658
    • Dalebroux, Z.D.1    Edwards, R.L.2    Swanson, M.S.3
  • 10
    • 77950211392 scopus 로고    scopus 로고
    • Distinct roles of ppGpp and DksA in Legionella pneumophila differentiation
    • Dalebroux ZD, Yagi BF, Sahr T, Buchrieser C, Swanson MS (2010b) Distinct roles of ppGpp and DksA in Legionella pneumophila differentiation. Mol Microbiol 76(1):200-219
    • (2010) Mol Microbiol , vol.76 , Issue.1 , pp. 200-219
    • Dalebroux, Z.D.1    Yagi, B.F.2    Sahr, T.3    Buchrieser, C.4    Swanson, M.S.5
  • 12
    • 0035085509 scopus 로고    scopus 로고
    • Flagellum of Legionella pneumophila positively affects the early phase of infection of eukaryotic host cells
    • DOI 10.1128/IAI.69.4.2116-2122.2001
    • Dietrich C, Heuner K, Brand BC, Hacker J, Steinert M (2001) Flagellum of Legionella pneumophila positively affects the early phase of infection of eukaryotic host cells. Infect Immun 69(4):2116-2122 (Pubitemid 32239676)
    • (2001) Infection and Immunity , vol.69 , Issue.4 , pp. 2116-2122
    • Dietrich, C.1    Heuner, K.2    Brand, B.C.3    Hacker, J.4    Steinert, M.5
  • 13
    • 0019409995 scopus 로고
    • Improved semiselective medium for isolation of Legionella pneumophila from contaminated clinical and environmental specimens
    • Edelstein PH (1981) Improved semiselective medium for isolation of Legionella pneumophila from contaminated clinical and environmental specimens. J Clin Microbiol 14(3):298-303 (Pubitemid 11052252)
    • (1981) Journal of Clinical Microbiology , vol.14 , Issue.3 , pp. 298-303
    • Edelstein, P.H.1
  • 14
    • 60649109691 scopus 로고    scopus 로고
    • Legionella pneumophila couples fatty acid flux to microbial differentiation and virulence
    • Edwards RL, Dalebroux ZD, Swanson MS (2009) Legionella pneumophila couples fatty acid flux to microbial differentiation and virulence. Mol Microbiol 71(5):1190-1204
    • (2009) Mol Microbiol , vol.71 , Issue.5 , pp. 1190-1204
    • Edwards, R.L.1    Dalebroux, Z.D.2    Swanson, M.S.3
  • 16
    • 0037381291 scopus 로고    scopus 로고
    • The Legionella pneumophila GacA homolog (LetA) is involved in the regulation of icm virulence genes and is required for intracellular multiplication in Acanthamoeba castellanii
    • DOI 10.1016/S0882-4010(03)00027-5
    • Gal-Mor O, Segal G (2003) The Legionella pneumophila GacA homolog (LetA) is involved in the regulation of icm virulence genes and is required for intracellular multiplication in Acanthamoeba castellanii. Microb Pathog 34(4):187-194 (Pubitemid 36369381)
    • (2003) Microbial Pathogenesis , vol.34 , Issue.4 , pp. 187-194
    • Gal-Mor, O.1    Segal, G.2
  • 17
    • 44349121198 scopus 로고    scopus 로고
    • Identification and characterization of a new conjugation/type IVA secretion system (trb/tra) of Legionella pneumophila Corby localized on two mobile genomic islands
    • DOI 10.1016/j.ijmm.2007.07.012, PII S1438422107001208
    • Glöckner G, Albert-Weissenberger C, Weinmann E, Jacobi S, Schunder E, Steinert M, Hacker J, Heuner K (2008) Identification and characterization of a new conjugation/type IVA secretion system (trb/tra) of Legionella pneumophila Corby localized on two mobile genomic islands. Int J Med Microbiol 298(5-6):411-428 (Pubitemid 351734789)
    • (2008) International Journal of Medical Microbiology , vol.298 , Issue.5-6 , pp. 411-428
    • Glockner, G.1    Albert-Weissenberger, C.2    Weinmann, E.3    Jacobi, S.4    Schunder, E.5    Steinert, M.6    Hacker, J.7    Heuner, K.8
  • 18
    • 0032838291 scopus 로고    scopus 로고
    • The Legionella pneumophila rpoS gene is required for growth within Acanthamoeba castellanii
    • Hales LM, Shuman HA (1999) The Legionella pneumophila rpoS gene is required for growth within Acanthamoeba castellanii. J Bacteriol 181(16):4879-4889 (Pubitemid 29383517)
    • (1999) Journal of Bacteriology , vol.181 , Issue.16 , pp. 4879-4889
    • Hales, L.M.1    Shuman, H.A.2
  • 19
    • 0022017233 scopus 로고
    • Bacterial endosymbionts of Acanthamoeba sp
    • Hall J, Voelz H (1985) Bacterial endosymbionts of Acanthamoeba sp. J Parasitol 71(1):89-95
    • (1985) J Parasitol , vol.71 , Issue.1 , pp. 89-95
    • Hall, J.1    Voelz, H.2
  • 20
    • 0032782866 scopus 로고    scopus 로고
    • Co-ordination of Legionella pneumophila virulence with entry into stationary phase by ppGpp
    • DOI 10.1046/j.1365-2958.1999.01519.x
    • Hammer BK, Swanson MS (1999) Co-ordination of Legionella pneumophila virulence with entry into stationary phase by ppGpp. Mol Microbiol 33(4):721-731 (Pubitemid 29392653)
    • (1999) Molecular Microbiology , vol.33 , Issue.4 , pp. 721-731
    • Hammer, B.K.1    Swanson, M.S.2
  • 21
    • 0036225745 scopus 로고    scopus 로고
    • A two-component regulator induces the transmission phenotype of stationary-phase Legionella pneumophila
    • DOI 10.1046/j.1365-2958.2002.02884.x
    • Hammer BK, Tateda ES, Swanson MS (2002) A two-component regulator induces the transmission phenotype of stationary-phase Legionella pneumophila. Mol Microbiol 44(1):107-118 (Pubitemid 34429768)
    • (2002) Molecular Microbiology , vol.44 , Issue.1 , pp. 107-118
    • Hammer, B.K.1    Tateda, E.S.2    Swanson, M.S.3
  • 22
    • 0020959710 scopus 로고
    • Studies on transformation of Escherichia coli with plasmids
    • Hanahan D (1983) Studies on transformation of Escherichia coli with plasmids. J Mol Biol 166(4):557-580 (Pubitemid 13027898)
    • (1983) Journal of Molecular Biology , vol.166 , Issue.4 , pp. 557-580
    • Hanahan, D.1
  • 23
    • 33845666673 scopus 로고    scopus 로고
    • Identification and serotyping of atypical Legionella pneumophila strains isolated from human and environmental sources
    • DOI 10.1111/j.1365-2672.2006.03057.x
    • Helbig JH, Benson RF, Pelaz C, Jacobs E, Lück PC (2007) Identification and serotyping of atypical Legionella pneumophila strains isolated from human and environmental sources. J Appl Microbiol 102(1):100-105 (Pubitemid 44952792)
    • (2007) Journal of Applied Microbiology , vol.102 , Issue.1 , pp. 100-105
    • Helbig, J.H.1    Benson, R.F.2    Pelaz, C.3    Jacobs, E.4    Luck, P.C.5
  • 24
    • 76749167807 scopus 로고    scopus 로고
    • The flagellar regulon of Legionella pneumophila and the expression of virulence traits
    • Heuner K, Swanson M (eds). Horizon Scientific Press, UK
    • Heuner K, Albert-Weissenberger C (2008) The flagellar regulon of Legionella pneumophila and the expression of virulence traits. In: Heuner K, Swanson M (eds) Legionella - Molecular Microbiology. Horizon Scientific Press, UK, pp 101-121
    • (2008) Legionella - Molecular Microbiology , pp. 101-121
    • Heuner, K.1    Albert-Weissenberger, C.2
  • 25
    • 0029034584 scopus 로고
    • Cloning and genetic characterization of the flagellum subunit gene (flaA) of Legionella pneumophila serogroup 1
    • Heuner K, Bender-Beck L, Brand BC, Luck PC, Mann KH, Marre R, Ott M, Hacker J (1995) Cloning and genetic characterization of the flagellum subunit gene (flaA) of Legionella pneumophila serogroup 1. Infect Immun 63(7):2499-2507
    • (1995) Infect Immun , vol.63 , Issue.7 , pp. 2499-2507
    • Heuner, K.1    Bender-Beck, L.2    Brand, B.C.3    Luck, P.C.4    Mann, K.H.5    Marre, R.6    Ott, M.7    Hacker, J.8
  • 26
    • 0031029457 scopus 로고    scopus 로고
    • 28 of Legionella pneumophila restores flagellation and motility to an Escherichia coli fliA mutant
    • Heuner K, Hacker J, Brand BC (1997) The alternative sigma factor sigma28 of Legionella pneumophila restores flagellation and motility to an Escherichia coli fliA mutant. J Bacteriol 179(1):17-23 (Pubitemid 26428460)
    • (1997) Journal of Bacteriology , vol.179 , Issue.1 , pp. 17-23
    • Heuner, K.1    Hacker, J.2    Brand, B.C.3
  • 27
    • 0035853474 scopus 로고    scopus 로고
    • Outer sheath associated proteins of the oral spirochete Treponema maltophilum
    • DOI 10.1016/S0378-1097(01)00104-5, PII S0378109701001045
    • Heuner K, Meltzer U, Choi BK, Gobel UB (2001) Outer sheath associated proteins of the oral spirochete Treponema maltophilum. FEMS Microbiol Lett 197(2):187-193 (Pubitemid 32324180)
    • (2001) FEMS Microbiology Letters , vol.197 , Issue.2 , pp. 187-193
    • Heuner, K.1    Meltzer, U.2    Choi, B.-K.3    Gobel, U.B.4
  • 28
    • 0036177978 scopus 로고    scopus 로고
    • 28 factor on virulence and flagellum expression of Legionella pneumophila
    • DOI 10.1128/IAI.70.3.1604-1608.2002
    • Heuner K, Dietrich C, Skriwan C, Steinert M, Hacker J (2002) Influence of the alternative sigma(28) factor on virulence and flagellum expression of Legionella pneumophila. Infect Immun 70(3):1604-1608 (Pubitemid 34163441)
    • (2002) Infection and Immunity , vol.70 , Issue.3 , pp. 1604-1608
    • Heuner, K.1    Dietrich, C.2    Skriwan, C.3    Steinert, M.4    Hacker, J.5
  • 29
    • 0028093390 scopus 로고
    • Roles of FliK and FlhB in determination of flagellar hook length in Salmonella typhimurium
    • Hirano T, Yamaguchi S, Oosawa K, Aizawa S (1994) Roles of FliK and FlhB in determination of flagellar hook length in Salmonella typhimurium. J Bacteriol 176(17):5439-5449 (Pubitemid 24273534)
    • (1994) Journal of Bacteriology , vol.176 , Issue.17 , pp. 5439-5449
    • Hirano, T.1    Yamaguchi, S.2    Oosawa, K.3    Aizawa, S.-I.4
  • 30
    • 0020591330 scopus 로고
    • Formation of a novel phagosome by the Legionnaires' disease bacterium (Legionella pneumophila) in human monocytes
    • Horwitz MA (1983) Formation of a novel phagosome by the Legionnaires' disease bacterium (Legionella pneumophila) in human monocytes. J Exp Med 158(4):1319-1331 (Pubitemid 13013435)
    • (1983) Journal of Experimental Medicine , vol.158 , Issue.4 , pp. 1319-1331
    • Horwitz, M.A.1
  • 31
    • 0021718023 scopus 로고
    • Legionella pneumophila inhibits acidification of its phagosome in human monocytes
    • DOI 10.1083/jcb.99.6.1936
    • Horwitz MA, Maxfield FR (1984) Legionella pneumophila inhibits acidification of its phagosome in human monocytes. J Cell Biol 99(6):1936-1943 (Pubitemid 15181854)
    • (1984) Journal of Cell Biology , vol.99 , Issue.6 , pp. 1936-1943
    • Horwitz, M.A.1    Maxfield, F.R.2
  • 32
    • 0018885613 scopus 로고
    • Legionnaires' disease bacterium (Legionella pneumophila) multiples intracellularly in human monocytes
    • Horwitz MA, Silverstein SC (1980) Legionnaires' disease bacterium (Legionella pneumophila) multiples intracellularly in human monocytes. J Clin Investig 66(3):441-450 (Pubitemid 10053907)
    • (1980) Journal of Clinical Investigation , vol.66 , Issue.3 , pp. 441-450
    • Horwitz, M.A.1    Silverstein, S.C.2
  • 33
    • 1942476063 scopus 로고    scopus 로고
    • 54 and the Transcriptional Regulator FleQ of Legionella pneumophila, Which Are Both Involved in the Regulation Cascade of Flagellar Gene Expression
    • DOI 10.1128/JB.186.9.2540-2547.2004
    • Jacobi S, Schade R, Heuner K (2004) Characterization of the alternative sigma factor sigma54 and the transcriptional regulator FleQ of Legionella pneumophila, which are both involved in the regulation cascade of flagellar gene expression. J Bacteriol 186(9):2540-2547 (Pubitemid 38525906)
    • (2004) Journal of Bacteriology , vol.186 , Issue.9 , pp. 2540-2547
    • Jacobi, S.1    Schade, R.2    Heuner, K.3
  • 34
    • 0022258991 scopus 로고
    • A comparison of virulence of two strains of Legionella pneumophila based on experimental aerosol infection of guinea-pigs
    • Jepras RI, Fitzgeorge RB, Baskerville A (1985) A comparison of virulence of two strains of Legionella pneumophila based on experimental aerosol infection of guinea-pigs. J Hyg 95(1):29-38 (Pubitemid 15002964)
    • (1985) Journal of Hygiene , vol.95 , Issue.1 , pp. 29-38
    • Jepras, R.I.1    Fitzgeorge, R.B.2    Baskerville, A.3
  • 35
    • 0018781964 scopus 로고
    • Transformations in isolated polyhooks
    • Kagawa H, Aizawa SI, Asakura S (1979) Transformations in isolated polyhooks. J Mol Biol 129(2):333-336
    • (1979) J Mol Biol , vol.129 , Issue.2 , pp. 333-336
    • Kagawa, H.1    Aizawa, S.I.2    Asakura, S.3
  • 36
    • 6044228192 scopus 로고    scopus 로고
    • S-dependent genes and identification of their promoter sequences
    • DOI 10.1128/JB.186.21.7186-7195.2004
    • Lacour S, Landini P (2004) SigmaS-dependent gene expression at the onset of stationary phase in Escherichia coli: function of sigmaS-dependent genes and identification of their promoter sequences. J Bacteriol 186(21):7186-7195 (Pubitemid 39383102)
    • (2004) Journal of Bacteriology , vol.186 , Issue.21 , pp. 7186-7195
    • Lacour, S.1    Landini, P.2
  • 37
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli UK (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227(5259):680-685
    • (1970) Nature , vol.227 , Issue.5259 , pp. 680-685
    • Laemmli, U.K.1
  • 38
    • 33645844248 scopus 로고    scopus 로고
    • Regulation of flagella
    • McCarter LL (2006) Regulation of flagella. Curr Opin Microbiol 9(2):180-186
    • (2006) Curr Opin Microbiol , vol.9 , Issue.2 , pp. 180-186
    • McCarter, L.L.1
  • 39
    • 0142125296 scopus 로고    scopus 로고
    • Legionella pneumophila CsrA is a pivotal repressor of transmission traits and activator of replication
    • DOI 10.1046/j.1365-2958.2003.03706.x
    • Molofsky AB, Swanson MS (2003) Legionella pneumophila CsrA is a pivotal repressor of transmission traits and activator of replication. Mol Microbiol 50(2):445-461 (Pubitemid 37297126)
    • (2003) Molecular Microbiology , vol.50 , Issue.2 , pp. 445-461
    • Molofsky, A.B.1    Swanson, M.S.2
  • 40
    • 3142512687 scopus 로고    scopus 로고
    • Differentiate to thrive: Lessons from the Legionella pneumophila life cycle
    • DOI 10.1111/j.1365-2958.2004.04129.x
    • Molofsky AB, Swanson MS (2004) Differentiate to thrive: lessons from the Legionella pneumophila life cycle. Mol Microbiol 53(1):29-40 (Pubitemid 38901377)
    • (2004) Molecular Microbiology , vol.53 , Issue.1 , pp. 29-40
    • Molofsky, A.B.1    Swanson, M.S.2
  • 41
    • 23944485009 scopus 로고    scopus 로고
    • Components of the Legionella pneumophila flagellar regulon contribute to multiple virulence traits, including lysosome avoidance and macrophage death
    • DOI 10.1128/IAI.73.9.5720-5734.2005
    • Molofsky AB, Shetron-Rama LM, Swanson MS (2005) Components of the Legionella pneumophila flagellar regulon contribute to multiple virulence traits, including lysosome avoidance and macrophage death. Infect Immun 73(9):5720-5734 (Pubitemid 41193007)
    • (2005) Infection and Immunity , vol.73 , Issue.9 , pp. 5720-5734
    • Molofsky, A.B.1    Shetron-Rama, L.M.2    Swanson, M.S.3
  • 42
    • 8544232750 scopus 로고    scopus 로고
    • Growth versus maintenance: A trade-off dictated by RNA polymerase availability and sigma factor competition?
    • DOI 10.1111/j.1365-2958.2004.04342.x
    • Nyström T (2004) Growth versus maintenance: a trade-off dictated by RNA polymerase availability and sigma factor competition? Mol Microbiol 54(4):855-862 (Pubitemid 39491023)
    • (2004) Molecular Microbiology , vol.54 , Issue.4 , pp. 855-862
    • Nystrom, T.1
  • 43
    • 37349052036 scopus 로고    scopus 로고
    • Sigma factors in Pseudomonas aeruginosa
    • DOI 10.1111/j.1574-6976.2007.00092.x
    • Potvin E, Sanschagrin F, Levesque RC (2008) Sigma factors in Pseudomonas aeruginosa. FEMS Microbiol Rev 32(1):38-55 (Pubitemid 350293915)
    • (2008) FEMS Microbiology Reviews , vol.32 , Issue.1 , pp. 38-55
    • Potvin, E.1    Sanschagrin, F.2    Levesque, R.C.3
  • 44
    • 65549169936 scopus 로고    scopus 로고
    • The LetA-RsmYZ-CsrA regulatory cascade, together with RpoS and PmrA, post-transcriptionally regulates stationary phase activation of Legionella pneumophila Icm/Dot effectors
    • Rasis M, Segal G (2009) The LetA-RsmYZ-CsrA regulatory cascade, together with RpoS and PmrA, post-transcriptionally regulates stationary phase activation of Legionella pneumophila Icm/Dot effectors. Mol Microbiol 72(4):995-1010
    • (2009) Mol Microbiol , vol.72 , Issue.4 , pp. 995-1010
    • Rasis, M.1    Segal, G.2
  • 45
    • 0022881556 scopus 로고
    • Current views on the relationships between amoebae, legionellae and man
    • Rowbotham TJ (1986) Current views on the relationships between amoebae, legionellae and man. Isr J Med Sci 22(9):678-689 (Pubitemid 17002623)
    • (1986) Israel Journal of Medical Sciences , vol.22 , Issue.9 , pp. 678-689
    • Rowbotham, T.J.1
  • 49
    • 23344445007 scopus 로고    scopus 로고
    • Specificity of Legionella pneumophila and Coxiella burnetii vacuoles and versatility of Legionella pneumophila revealed by coinfection
    • DOI 10.1128/IAI.73.8.4494-4504.2005
    • Sauer JD, Shannon JG, Howe D, Hayes SF, Swanson MS, Heinzen RA (2005b) Specificity of Legionella pneumophila and Coxiella burnetii vacuoles and versatility of Legionella pneumophila revealed by coinfection. Infect Immun 73(8):4494-4504 (Pubitemid 41105603)
    • (2005) Infection and Immunity , vol.73 , Issue.8 , pp. 4494-4504
    • Sauer, J.-D.1    Shannon, J.G.2    Howe, D.3    Hayes, S.F.4    Swanson, M.S.5    Heinzen, R.A.6
  • 51
    • 0013147211 scopus 로고    scopus 로고
    • The ΔfliD mutant of Pseudomonas syringae pv. tabaci, which secretes flagellin monomers, induces a strong hypersensitive reaction (HR) in non-host tomato cells
    • Shimizu R, Taguchi F, Marutani M, Mukaihara T, Inagaki Y, Toyoda K, Shiraishi T, Ichinose Y (2003) The DeltafliD mutant of Pseudomonas syringae pv. tabaci, which secretes flagellin monomers, induces a strong hypersensitive reaction (HR) in non-host tomato cells. Mol Genet Genomics 269(1):21-30 (Pubitemid 36560677)
    • (2003) Molecular Genetics and Genomics , vol.269 , Issue.1 , pp. 21-30
    • Shimizu, R.1    Taguchi, F.2    Marutani, M.3    Mukaihara, T.4    Inagaki, Y.5    Toyoda, K.6    Shiraishi, T.7    Ichinose, Y.8
  • 52
    • 0344791690 scopus 로고    scopus 로고
    • Natural competence for DNA transformation by Legionella pneumophila and its association with expression of type IV pili
    • Stone BJ, Kwaik YA (1999) Natural competence for DNA transformation by Legionella pneumophila and its association with expression of type IV pili. J Bacteriol 181(5):1395-1402 (Pubitemid 29110796)
    • (1999) Journal of Bacteriology , vol.181 , Issue.5 , pp. 1395-1402
    • Stone, B.J.1    Abu Kwaik, Y.2
  • 53
    • 0034613726 scopus 로고    scopus 로고
    • Legionella pneumophila replication vacuoles mature into acidic, endocytic organelles
    • Sturgill-Koszycki S, Swanson MS (2000) Legionella pneumophila replication vacuoles mature into acidic, endocytic organelles. J Exp Med 192(9):1261-1272
    • (2000) J Exp Med , vol.192 , Issue.9 , pp. 1261-1272
    • Sturgill-Koszycki, S.1    Swanson, M.S.2
  • 54
    • 35948965245 scopus 로고    scopus 로고
    • The Legionella pneumophila response regulator LqsR promotes host cell interactions as an element of the virulence regulatory network controlled by RpoS and LetA
    • DOI 10.1111/j.1462-5822.2007.01005.x
    • Tiaden A, Spirig T, Weber SS, Bruggemann H, Bosshard R, Buchrieser C, Hilbi H (2007) The Legionella pneumophila response regulator LqsR promotes host cell interactions as an element of the virulence regulatory network controlled by RpoS and LetA. Cell Microbiol 9(12):2903-2920 (Pubitemid 350066574)
    • (2007) Cellular Microbiology , vol.9 , Issue.12 , pp. 2903-2920
    • Tiaden, A.1    Spirig, T.2    Weber, S.S.3    Bruggemann, H.4    Bosshard, R.5    Buchrieser, C.6    Hilbi, H.7
  • 55
    • 0036136235 scopus 로고    scopus 로고
    • Characterization of a Legionella pneumophila relA insertion mutant and roles of RelA and RpoS in virulence gene expression
    • DOI 10.1128/JB.184.1.67-75.2002
    • Zusman T, Gal-Mor O, Segal G (2002) Characterization of a Legionella pneumophila relA insertion mutant and roles of RelA and RpoS in virulence gene expression. J Bacteriol 184(1):67-75 (Pubitemid 34003285)
    • (2002) Journal of Bacteriology , vol.184 , Issue.1 , pp. 67-75
    • Zusman, T.1    Gal-Mor, O.2    Segal, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.