Plantagiolides I and J, two new withanolide glucosides from Tacca plantaginea with nuclear factor-kappaB inhibitory and peroxisome proliferator-activated receptor transactivational activities

Chemical and Pharmaceutical Bulletin

Volumn 60, Issue 12, 2012, Pages 1494-1501

  Quang, Tran Hong ^a,b   Ngan, Nguyen Thi Thanh ^a   Van Minh, Chau ^b   Van Kiem, Phan ^b   Yen, Pham Hai ^b   Tai, Bui Huu ^a,b   Nhiem, Nguyen Xuan ^a,b   Thao, Nguyen Phuong ^a,b   Anh, Hoang Le Tuan ^b   Luyen, Bui Thi Thuy ^a   Yang, Seo Young ^a   Kim, Young Ho ^a  

^a Chungnam National University   (South Korea)

^b GRADUATE UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Viet Nam)

Author keywords

GAL 4 peroxisome proliferator activated receptor chimera assay; Nuclear factor kappaB luciferase assay; Peroxisome proliferator response element luciferase assay; Plantagiolide; Tacca plantaginea; Withanolide glucoside

Indexed keywords

16BETA [[5 (BETA DEXTRO GLUCOPYRANOSYLOXY) 4 METHYL 1 OXOPENTYL]OXY] 3BETA [(2 ALPHA LEVO RHAMNOPYRANOSYL (1-2) 2 [ALPHA LEVO RHAMNOPYRANOSYL (1-3) BETA DEXTRO GLUCOPYRANOSYL)OXY]PREGN 5 EN 20 ONE; 1ALPHA,5ALPHA,16BETA TRIHYDROXYWITH 2ALPHA,3ALPHA,6ALPHA,7ALPHA DIEPOXY 12ALPHA ACETOXY 27 [(BETA DEXTRO GLUCOPYRANOSYL)OXY] 24 ENOLIDE; 26 O BETA DEXTRO GLUCOPYRANOSYL 3BETA,22EPSILON,26 TRIOL FUROST 5 ENE 3 O ALPHA LEVO RHAMNOPYRANOSYL[1-2] ALPHA LEVO RHAMNOPYRANOSYL[1-3] BETA DEXTRO GLUCOPYRANOSIDE; ANTIINFLAMMATORY AGENT; CHANTRIOLIDE A; CHANTRIOLIDE B; GLUCOSIDE; GUSANLUNGIONOSIDE D; I KAPPA B; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR AGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA AGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA AGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA AGONIST; PLANTAGIOLIDE I; PLANTAGIOLIDE J; ROSEOSIDE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; WITHANOLIDE;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL STRAIN HEPG2; DRUG ISOLATION; DRUG STRUCTURE; HUMAN; HUMAN CELL; IC 50; INFLAMMATION; MEDICINAL PLANT; METABOLIC DISORDER; TACA PLANTAGINEA; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION;

DIOSCOREACEAE; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUCOSIDES; HEP G2 CELLS; HUMANS; MOLECULAR CONFORMATION; NF-KAPPA B; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS; PLANT EXTRACTS; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSCRIPTIONAL ACTIVATION; TUMOR CELLS, CULTURED; WITHANOLIDES;

EID: 84871208919     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.c12-00550     Document Type: Article

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