-
1
-
-
50249105938
-
Tailoring T-cell receptor signals by proximal negative feedback mechanisms
-
Acuto O, Di Bartolo V, Michel F. 2008. Tailoring T-cell receptor signals by proximal negative feedback mechanisms. Nat Rev Immunol 8:699-712.
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 699-712
-
-
Acuto, O.1
Di Bartolo, V.2
Michel, F.3
-
2
-
-
0037077094
-
Induction of T helper type 2 immunity by a point mutation in the LAT adaptor
-
DOI 10.1126/science.1069057
-
Aguado E, Richelme S, Nunez-Cruz S, Miazek A, Mura AM, Richelme M, Guo XJ, Sainty D, He HT, Malissen B, Malissen M. 2002. Induction of T helper type 2 immunity by a point mutation in the LAT adaptor. Science 296:2036-2040. (Pubitemid 34627528)
-
(2002)
Science
, vol.296
, Issue.5575
, pp. 2036-2040
-
-
Aguado, E.1
Richelme, S.2
Nunez-Cruz, S.3
Miazek, A.4
Mura, A.-M.5
Richelme, M.6
Guo, X.-J.7
Sainty, D.8
He, H.-T.9
Malissen, B.10
Malissen, M.11
-
3
-
-
79952607098
-
Enhanced T-cell signaling in cells bearing linker for activation of T-cell (LAT) molecules resistant to ubiquitylation
-
Balagopalan L, Ashwell BA, Bernot KM, Akpan IO, Quasba N, Barr VA, Samelson LE. 2011. Enhanced T-cell signaling in cells bearing linker for activation of T-cell (LAT) molecules resistant to ubiquitylation. Proc Natl Acad Sci USA 108:2885-2890.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 2885-2890
-
-
Balagopalan, L.1
Ashwell, B.A.2
Bernot, K.M.3
Akpan, I.O.4
Quasba, N.5
Barr, V.A.6
Samelson, L.E.7
-
4
-
-
11144354114
-
Dynamic recruitment of the adaptor protein LAT: LAT exists in two distinct intracellular pools and controls its own recruitment
-
DOI 10.1242/jcs.00968
-
Bonello G, Blanchard N, Montoya MC, Aguado E, Langlet C, He HT, Nunez-Cruz S, Malissen M, Sanchez-Madrid F, Olive D, Hivroz C, Collette Y. 2004. Dynamic recruitment of the adaptor protein LAT: LAT exists in two distinct intra-cellular pools and controls its own recruitment. J Cell Sci 117:1009-1016. (Pubitemid 38456083)
-
(2004)
Journal of Cell Science
, vol.117
, Issue.7
, pp. 1009-1016
-
-
Bonello, G.1
Blanchard, N.2
Montoya, M.C.3
Aguado, E.4
Langlet, C.5
He, H.-T.6
Nunez-Cruz, S.7
Malissen, M.8
Sanchez-Madrid, F.9
Olive, D.10
Hivroz, C.11
Collette, Y.12
-
5
-
-
28844494497
-
Evidences for ubiquitination and intracellular trafficking of LAT, the linker of activated T cells
-
DOI 10.1016/j.bbamcr.2005.08.009, PII S0167488905001825
-
Brignatz C, Restouin A, Bonello G, Olive D, Collette Y. 2005. Evidences for ubiquitination and intracellular trafficking of LAT, the linker of activated T cells. Biochim Biophys Acta 1746:108-115. (Pubitemid 41774285)
-
(2005)
Biochimica et Biophysica Acta - Molecular Cell Research
, vol.1746
, Issue.2
, pp. 108-115
-
-
Brignatz, C.1
Restouin, A.2
Bonello, G.3
Olive, D.4
Collette, Y.5
-
6
-
-
33750530393
-
T cell receptor for antigen induces linker for activation of T cell-dependent activation of a negative signaling complex involving Dok-2, SHIP-1, and Grb-2
-
DOI 10.1084/jem.20060650
-
Dong S, Corre B, Foulon E, Dufour E, Veillette A, Acuto O, Michel F. 2006. T cell receptor for antigen induces linker for activation of T cell-dependent activation of a negative signaling complex involving Dok-2, SHIP-1, and Grb-2. J Exp Med 203:2509-2518. (Pubitemid 44664620)
-
(2006)
Journal of Experimental Medicine
, vol.203
, Issue.11
, pp. 2509-2518
-
-
Dong, S.1
Corre, B.2
Foulon, E.3
Dufour, E.4
Veillette, A.5
Acuto, O.6
Michel, F.7
-
7
-
-
78649794391
-
T cell receptor signal initiation induced by low-grade stimulation requires the cooperation of LAT in human T cells
-
Dong S, Corre B, Nika K, Pellegrini S, Michel F. 2010. T cell receptor signal initiation induced by low-grade stimulation requires the cooperation of LAT in human T cells. PLoS One 5:e15114.
-
(2010)
PLoS One
, vol.5
-
-
Dong, S.1
Corre, B.2
Nika, K.3
Pellegrini, S.4
Michel, F.5
-
8
-
-
36549076105
-
+ T cells of patients with systemic lupus erythematosus
-
DOI 10.1007/s10067-007-0644-8
-
Januchowski R, Wudarski M, Chwalinska-Sadowska H, Jagodzinski PP. 2008. Prevalence of ZAP-70, LAT, SLP-76, and DNA methyltransferase 1 expression in CD4+ T cells of patients with systemic lupus erythematosus. Clin Rheumatol 27:21-27. (Pubitemid 350182673)
-
(2008)
Clinical Rheumatology
, vol.27
, Issue.1
, pp. 21-27
-
-
Januchowski, R.1
Wudarski, M.2
Chwalinska-Sadowska, H.3
Jagodzinski, P.P.4
-
9
-
-
0037653244
-
Increased ubiquitination and reduced expression of LCK in T lymphocytes from patients with systemic lupus erythematosus
-
DOI 10.1002/art.10978
-
Jury EC, Kabouridis PS, Abba A, Mageed RA, Isenberg DA. 2003. Increased ubiquitination and reduced expression of LCK in T lymphocytes from patients with systemic lupus erythematosus. Arthritis Rheum 48:1343-1354. (Pubitemid 36554533)
-
(2003)
Arthritis and Rheumatism
, vol.48
, Issue.5
, pp. 1343-1354
-
-
Jury, E.C.1
Kabouridis, P.S.2
Abba, A.3
Mageed, R.A.4
Isenberg, D.A.5
-
10
-
-
2142710163
-
Altered lipid raft-associated signaling and ganglioside expression in T lymphocytes from patients with systemic lupus erythematosus
-
DOI 10.1172/JCI200420345
-
Jury EC, Kabouridis PS, Flores-Borja F, Mageed RA, Isenberg DA. 2004. Altered lipid raft-associated signaling and ganglioside expression in T lymphocytes from patients with systemic lupus erythematosus. J Clin Invest 113:1176-1187. (Pubitemid 38544103)
-
(2004)
Journal of Clinical Investigation
, vol.113
, Issue.8
, pp. 1176-1187
-
-
Jury, E.C.1
Kabouridis, P.S.2
Flores-Borja, F.3
Mageed, R.A.4
Isenberg, D.A.5
-
11
-
-
0038363406
-
Selective interaction of LAT (linker of activated T cells) with the open-active form of Lck in lipid rafts reveals a new mechanism for the regulation of Lck in T cells
-
DOI 10.1042/BJ20021578
-
Kabouridis PS. 2003. Selective interaction of LAT (linker of activated T cells) with the open-active form of Lck in lipid rafts reveals a new mechanism for the regulation of Lck in T cells. Biochem J 371:907-915. (Pubitemid 36578889)
-
(2003)
Biochemical Journal
, vol.371
, Issue.3
, pp. 907-915
-
-
Kabouridis, P.S.1
-
12
-
-
84954358117
-
Lipid rafts and T-lymphocyte function: Implications for autoimmunity
-
Kabouridis PS, Jury EC. 2008. Lipid rafts and T-lymphocyte function: implications for autoimmunity. FEBS Lett 582:3711-3718.
-
(2008)
FEBS Lett
, vol.582
, pp. 3711-3718
-
-
Kabouridis, P.S.1
Jury, E.C.2
-
13
-
-
6344278020
-
Linker for activation of T cells integrates positive and negative signaling in mast cells
-
Malbec O, Malissen M, Isnardi I, Lesourne R, Mura AM, Fridman WH, Malissen B, Daeron M. 2004. Linker for activation of T cells integrates positive and negative signaling in mast cells. J Immunol 173:5086-5094. (Pubitemid 39387791)
-
(2004)
Journal of Immunology
, vol.173
, Issue.8
, pp. 5086-5094
-
-
Malbec, O.1
Malissen, M.2
Isnardi, I.3
Lesourne, R.4
Mura, A.-M.5
Fridman, W.H.6
Malissen, B.7
Daeron, M.8
-
14
-
-
3342912122
-
Negative feedback loop in T-cell activation through MAPK-catalyzed threonine phosphorylation of LAT
-
DOI 10.1038/sj.emboj.7600268
-
Matsuda S, Miwa Y, Hirata Y, Minowa A, Tanaka J, Nishida E, Koyasu S. 2004. Negative feedback loop in T-cell activation through MAPK-catalyzed threonine phosphorylation of LAT. EMBO J 23:2577-2585. (Pubitemid 38988229)
-
(2004)
EMBO Journal
, vol.23
, Issue.13
, pp. 2577-2585
-
-
Matsuda, S.1
Miwa, Y.2
Hirata, Y.3
Minowa, A.4
Tanaka, J.5
Nishida, E.6
Koyasu, S.7
-
15
-
-
68649087416
-
Loss of the LAT adaptor converts antigen-responsive T cells into pathogenic effectors that function independently of the T cell receptor
-
Mingueneau M, Roncagalli R, Gregoire C, Kissenpfennig A, Miazek A, Archambaud C, Wang Y, Perrin P, Bertosio E, Sansoni A, Richelme S, Locksley RM, Aguado E, Malissen M, Malissen B. 2009. Loss of the LAT adaptor converts antigen-responsive T cells into pathogenic effectors that function independently of the T cell receptor. Immunity 31:197-208.
-
(2009)
Immunity
, vol.31
, pp. 197-208
-
-
Mingueneau, M.1
Roncagalli, R.2
Gregoire, C.3
Kissenpfennig, A.4
Miazek, A.5
Archambaud, C.6
Wang, Y.7
Perrin, P.8
Bertosio, E.9
Sansoni, A.10
Richelme, S.11
Locksley, R.M.12
Aguado, E.13
Malissen, M.14
Malissen, B.15
-
16
-
-
77953911933
-
Constitutively active Lck kinase in T cells drives antigen receptor signal transduction
-
Nika K, Soldani C, Salek M, Paster W, Gray A, Etzensperger R, Fugger L, Polzella P, Cerundolo V, Dushek O, Hofer T, Viola A, Acuto O. 2010. Constitutively active Lck kinase in T cells drives antigen receptor signal transduction. Immunity 32:766-777.
-
(2010)
Immunity
, vol.32
, pp. 766-777
-
-
Nika, K.1
Soldani, C.2
Salek, M.3
Paster, W.4
Gray, A.5
Etzensperger, R.6
Fugger, L.7
Polzella, P.8
Cerundolo, V.9
Dushek, O.10
Hofer, T.11
Viola, A.12
Acuto, O.13
-
17
-
-
61449170053
-
Genetically encoded For-ster resonance energy transfer sensors for the conformation of the Src family kinase Lck
-
Paster W, Paar C, Eckerstorfer P, Jakober A, Drbal K, Schutz GJ, Sonnleitner A, Stockinger H. 2009. Genetically encoded For-ster resonance energy transfer sensors for the conformation of the Src family kinase Lck. J Immunol 182:2160-2167.
-
(2009)
J Immunol
, vol.182
, pp. 2160-2167
-
-
Paster, W.1
Paar, C.2
Eckerstorfer, P.3
Jakober, A.4
Drbal, K.5
Schutz, G.J.6
Sonnleitner, A.7
Stockinger, H.8
-
18
-
-
77954625014
-
LAT signaling pathology: An 'autoimmune' condition without T cell self-reactivity
-
Roncagalli R, Mingueneau M, Gregoire C, Malissen M, Malissen B. 2010. LAT signaling pathology: An 'autoimmune' condition without T cell self-reactivity. Trends Immunol 31:253-259.
-
(2010)
Trends Immunol
, vol.31
, pp. 253-259
-
-
Roncagalli, R.1
Mingueneau, M.2
Gregoire, C.3
Malissen, M.4
Malissen, B.5
-
19
-
-
61849128182
-
T-cell receptor proximal signaling via the Src-family kinases, Lck and Fyn, influences T-cell activation, differentiation, and tolerance
-
Salmond RJ, Filby A, Qureshi I, Caserta S, Zamoyska R. 2009. T-cell receptor proximal signaling via the Src-family kinases, Lck and Fyn, influences T-cell activation, differentiation, and tolerance. Immunol Rev 228:9-22.
-
(2009)
Immunol Rev
, vol.228
, pp. 9-22
-
-
Salmond, R.J.1
Filby, A.2
Qureshi, I.3
Caserta, S.4
Zamoyska, R.5
-
20
-
-
0031452274
-
Structures of Src-family tyrosine kinases
-
DOI 10.1016/S0959-440X(97)80146-7
-
Sicheri F, Kuriyan J. 1997. Structures of Src-family tyrosine kinases. Curr Opin Struct Biol 7:777-785. (Pubitemid 28025103)
-
(1997)
Current Opinion in Structural Biology
, vol.7
, Issue.6
, pp. 777-785
-
-
Sicheri, F.1
Kuriyan, J.2
-
22
-
-
0037076975
-
A LAT mutation that inhibits T cell development yet induces lymphoproliferation
-
DOI 10.1126/science.1069066
-
Sommers CL, Park CS, Lee J, Feng C, Fuller CL, Grinberg A, Hildebrand JA, Lacana E, Menon RK, Shores EW, Samelson LE, Love PE. 2002. A LAT mutation that inhibits T cell development yet induces lymphoproliferation. Science 296:2040-2043. (Pubitemid 34627529)
-
(2002)
Science
, vol.296
, Issue.5575
, pp. 2040-2043
-
-
Sommers, C.L.1
Park, C.-S.2
Lee, J.3
Feng, C.4
Fuller, C.L.5
Grinberg, A.6
Hildebrand, J.A.7
Lacana, E.8
Menon, R.K.9
Shores, E.W.10
Samelson, L.E.11
Love, P.E.12
-
23
-
-
0345743609
-
LAT: A T lymphocyte adapter protein that couples the antigen receptor to downstream signaling pathways
-
DOI 10.1002/bies.10384
-
Sommers CL, Samelson LE, Love PE. 2004. LAT: A T lymphocyte adapter protein that couples the antigen receptor to downstream signaling pathways. Bioessays 26:61-67. (Pubitemid 38095349)
-
(2004)
BioEssays
, vol.26
, Issue.1
, pp. 61-67
-
-
Sommers, C.L.1
Samelson, L.E.2
Love, P.E.3
-
24
-
-
65849472289
-
At the crossroads of homoeostasis and disease: Roles of the PACS proteins in membrane traffic and apoptosis
-
Youker RT, Shinde U, Day R, Thomas G. 2009. At the crossroads of homoeostasis and disease: Roles of the PACS proteins in membrane traffic and apoptosis. Biochem J 421:1-15.
-
(2009)
Biochem J
, vol.421
, pp. 1-15
-
-
Youker, R.T.1
Shinde, U.2
Day, R.3
Thomas, G.4
-
25
-
-
0032498231
-
LAT: The ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation
-
DOI 10.1016/S0092-8674(00)80901-0
-
Zhang W, Sloan-Lancaster J, Kitchen J, Trible RP, Samelson LE. 1998. LAT: The ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation. Cell 92:83-92. (Pubitemid 28053300)
-
(1998)
Cell
, vol.92
, Issue.1
, pp. 83-92
-
-
Zhang, W.1
Sloan-Lancaster, J.2
Kitchen, J.3
Trible, R.P.4
Samelson, L.E.5
-
26
-
-
0034725625
-
Association of Grb2, Gads, and phospholipase C-γ1 with phosphorylated LAT tyrosine residues: Effect of LAT tyrosine mutations on T cell antigen receptor-mediated signaling
-
DOI 10.1074/jbc.M000404200
-
Zhang W, Trible RP, Zhu M, Liu SK, Mcglade CJ, Samelson LE. 2000. Association of Grb2, Gads, and phospho-lipase C-gamma 1 with phosphorylated LAT tyrosine residues. Effect of LAT tyrosine mutations on T cell antigen receptor-mediated signaling. J Biol Chem 275:23355-23361. (Pubitemid 30646238)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.30
, pp. 23355-23361
-
-
Zhang, W.1
Trible, R.P.2
Zhu, M.3
Liu, S.K.4
McGlade, C.J.5
Samelson, L.E.6
|