메뉴 건너뛰기




Volumn 8, Issue 4, 2012, Pages 244-250

Opinion: Restoring the renal microvasculature to treat chronic kidney disease

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; ANGIOPOIETIN 1; COMP ANGIOPOIETIN 1; GROWTH FACTOR; MICRORNA; MICRORNA 132; RECOMBINANT ANGIOPOIETIN 1; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG; VASCULOTROPIN A; VASCULOTROPIN A[1-121]; ANGIOGENIC FACTOR;

EID: 84858998542     PISSN: 17595061     EISSN: 1759507X     Source Type: Journal    
DOI: 10.1038/nrneph.2011.219     Document Type: Review
Times cited : (83)

References (52)
  • 1
    • 0037228105 scopus 로고    scopus 로고
    • Prevalence of chronic kidney disease and decreased kidney function in the adult US population: Third National Health and Nutrition Examination Survey
    • Coresh, J., Astor, B. C., Greene, T., Eknoyan, G. & Levey, A. S. Prevalence of chronic kidney disease and decreased kidney function in the adult US population: Third National Health and Nutrition Examination Survey. Am. J. Kidney Dis. 41, 1-12 (2003).
    • (2003) Am. J. Kidney Dis. , vol.41 , pp. 1-12
    • Coresh, J.1    Astor, B.C.2    Greene, T.3    Eknoyan, G.4    Levey, A.S.5
  • 2
    • 0031949073 scopus 로고    scopus 로고
    • Progressive renal disease: The chronic hypoxia hypothesis
    • Fine, L. G., Orphanides, C. & Norman, J. T. Progressive renal disease: the chronic hypoxia hypothesis. Kidney Int. Suppl. 65, S74-S78 (1998).
    • (1998) Kidney Int. Suppl. , vol.65
    • Fine, L.G.1    Orphanides, C.2    Norman, J.T.3
  • 3
    • 33645452371 scopus 로고    scopus 로고
    • Chronic hypoxia and tubulointerstitial injury: A final common pathway to end-stage renal failure
    • Nangaku, M. Chronic hypoxia and tubulointerstitial injury: a final common pathway to end-stage renal failure. J. Am. Soc. Nephrol. 17, 17-25 (2006).
    • (2006) J. Am. Soc. Nephrol. , vol.17 , pp. 17-25
    • Nangaku, M.1
  • 4
    • 79956328903 scopus 로고    scopus 로고
    • Molecular mechanisms and clinical applications of angiogenesis
    • Carmeliet, P. & Jain, R. K. Molecular mechanisms and clinical applications of angiogenesis. Nature 473, 298-307 (2011).
    • (2011) Nature , vol.473 , pp. 298-307
    • Carmeliet, P.1    Jain, R.K.2
  • 6
    • 79953886254 scopus 로고    scopus 로고
    • Capillary rarefaction, hypoxia, VEGF and angiogenesis in chronic renal disease
    • Mayer, G. Capillary rarefaction, hypoxia, VEGF and angiogenesis in chronic renal disease. Nephrol. Dial. Transplant. 26, 1132-1137 (2011).
    • (2011) Nephrol. Dial. Transplant. , vol.26 , pp. 1132-1137
    • Mayer, G.1
  • 7
    • 0034917262 scopus 로고    scopus 로고
    • Impaired angiogenesis in the remnant kidney model: II. Vascular endothelial growth factor administration reduces renal fibrosis and stabilizes renal function
    • Kang, D. H., Hughes, J., Mazzali, M., Schreiner, G. F. & Johnson, R. J. Impaired angiogenesis in the remnant kidney model: II. Vascular endothelial growth factor administration reduces renal fibrosis and stabilizes renal function. J. Am. Soc. Nephrol. 12, 1448-1457 (2001).
    • (2001) J. Am. Soc. Nephrol. , vol.12 , pp. 1448-1457
    • Kang, D.H.1    Hughes, J.2    Mazzali, M.3    Schreiner, G.F.4    Johnson, R.J.5
  • 9
    • 33748065982 scopus 로고    scopus 로고
    • COMP-Angiopoietin-1 ameliorates renal fibrosis in a unilateral ureteral obstruction model
    • Kim, W. et al. COMP-Angiopoietin-1 ameliorates renal fibrosis in a unilateral ureteral obstruction model. J. Am. Soc. Nephrol. 17, 2474-2483 (2006).
    • (2006) J. Am. Soc. Nephrol. , vol.17 , pp. 2474-2483
    • Kim, W.1
  • 10
    • 47349088687 scopus 로고    scopus 로고
    • Angiopoietin-1 therapy enhances fibrosis and inflammation following folic acid-induced acute renal injury
    • Long, D. A. et al. Angiopoietin-1 therapy enhances fibrosis and inflammation following folic acid-induced acute renal injury. Kidney Int. 74, 300-309 (2008).
    • (2008) Kidney Int. , vol.74 , pp. 300-309
    • Long, D.A.1
  • 11
    • 80052475033 scopus 로고    scopus 로고
    • Selective stimulation of VEGFR2 accelerates progressive renal disease
    • Sato, W. et al. Selective stimulation of VEGFR2 accelerates progressive renal disease. Am. J. Pathol. 179, 155-166 (2011).
    • (2011) Am. J. Pathol. , vol.179 , pp. 155-166
    • Sato, W.1
  • 12
    • 23844548897 scopus 로고    scopus 로고
    • Pathophysiological role of vascular endothelial growth factor in the remnant kidney
    • Schrijvers, B. F. et al. Pathophysiological role of vascular endothelial growth factor in the remnant kidney. Nephron Exp. Nephrol. 101, e9-e15 (2005).
    • (2005) Nephron Exp. Nephrol. , vol.101
    • Schrijvers, B.F.1
  • 14
    • 79954466760 scopus 로고    scopus 로고
    • Amelioration of renal alterations in obese type 2 diabetic mice by vasohibin-1, a negative feedback regulator of angiogenesis
    • Saito, D. et al. Amelioration of renal alterations in obese type 2 diabetic mice by vasohibin-1, a negative feedback regulator of angiogenesis. Am. J. Physiol. Renal Physiol. 300, F873-F886 (2011).
    • (2011) Am. J. Physiol. Renal Physiol. , vol.300
    • Saito, D.1
  • 15
    • 57349093841 scopus 로고    scopus 로고
    • VEGF-121 preserves renal microvessel structure and ameliorates secondary renal disease following acute kidney injury
    • Leonard, E. C., Friedrich, J. L. & Basile, D. P. VEGF-121 preserves renal microvessel structure and ameliorates secondary renal disease following acute kidney injury. Am. J. Physiol. Renal Physiol. 295, F1648-F1657 (2008).
    • (2008) Am. J. Physiol. Renal Physiol. , vol.295
    • Leonard, E.C.1    Friedrich, J.L.2    Basile, D.P.3
  • 16
    • 58849142993 scopus 로고    scopus 로고
    • Angiostatin overexpression is associated with an improvement in chronic kidney injury by an anti-inflammatory mechanism
    • Mu, W. et al. Angiostatin overexpression is associated with an improvement in chronic kidney injury by an anti-inflammatory mechanism. Am. J. Physiol. Renal Physiol. 296, F145-F152 (2009).
    • (2009) Am. J. Physiol. Renal Physiol. , vol.296
    • Mu, W.1
  • 17
    • 34249052234 scopus 로고    scopus 로고
    • TGF-beta in renal injury and disease
    • Bottinger, E. P. TGF-beta in renal injury and disease. Semin. Nephrol. 27, 309-320 (2007).
    • (2007) Semin. Nephrol. , vol.27 , pp. 309-320
    • Bottinger, E.P.1
  • 18
    • 7244248552 scopus 로고    scopus 로고
    • Lack of the growth factor midkine enhances survival against cisplatin-induced renal damage
    • Kawai, H. et al. Lack of the growth factor midkine enhances survival against cisplatin-induced renal damage. Am. J. Pathol. 165, 1603-1612 (2004).
    • (2004) Am. J. Pathol. , vol.165 , pp. 1603-1612
    • Kawai, H.1
  • 19
    • 34548070176 scopus 로고    scopus 로고
    • Development of renal-targeted vector through combined in vivo phage display and capsid engineering of adenoviral fibers from serotype 19p
    • Denby, L. et al. Development of renal-targeted vector through combined in vivo phage display and capsid engineering of adenoviral fibers from serotype 19p. Mol. Ther. 15, 1647-1654 (2007).
    • (2007) Mol. Ther. , vol.15 , pp. 1647-1654
    • Denby, L.1
  • 20
    • 79960019666 scopus 로고    scopus 로고
    • Capillary enlargement, not sprouting angiogenesis, determines beneficial therapeutic effects and side effects of angiogenic gene therapy
    • Korpisalo, P. et al. Capillary enlargement, not sprouting angiogenesis, determines beneficial therapeutic effects and side effects of angiogenic gene therapy. Eur. Heart J. 32, 1664-1672 (2011).
    • (2011) Eur. Heart J. , vol.32 , pp. 1664-1672
    • Korpisalo, P.1
  • 21
    • 33746257413 scopus 로고    scopus 로고
    • Permeability properties of tumor surrogate blood vessels induced by VEGF.-A
    • Nagy, J. A. et al. Permeability properties of tumor surrogate blood vessels induced by VEGF.-A. Lab. Invest. 86, 767-780 (2006).
    • (2006) Lab. Invest. , vol.86 , pp. 767-780
    • Nagy, J.A.1
  • 22
    • 37848998838 scopus 로고    scopus 로고
    • Angiopoietin-1 prevents VEGF-induced endothelial permeability by sequestering Src through mDia
    • Gavard, J., Patel, V. & Gutkind, J. S. Angiopoietin-1 prevents VEGF-induced endothelial permeability by sequestering Src through mDia. Dev. Cell 14, 25-36 (2008).
    • (2008) Dev. Cell , vol.14 , pp. 25-36
    • Gavard, J.1    Patel, V.2    Gutkind, J.S.3
  • 23
    • 0035476509 scopus 로고    scopus 로고
    • Induction of hypervascularity without leakage or inflammation in transgenic mice overexpressing hypoxia-inducible factor-1
    • Elson, D. A. et al. Induction of hypervascularity without leakage or inflammation in transgenic mice overexpressing hypoxia-inducible factor-1. Genes Dev. 15, 2520-2532 (2001).
    • (2001) Genes Dev. , vol.15 , pp. 2520-2532
    • Elson, D.A.1
  • 24
    • 25144475141 scopus 로고    scopus 로고
    • Cobalt promotes angiogenesis via hypoxia-inducible factor and protects tubulointerstitium in the remnant kidney model
    • Tanaka, T. et al. Cobalt promotes angiogenesis via hypoxia-inducible factor and protects tubulointerstitium in the remnant kidney model. Lab. Invest. 85, 1292-1307 (2005).
    • (2005) Lab. Invest. , vol.85 , pp. 1292-1307
    • Tanaka, T.1
  • 25
    • 36849021771 scopus 로고    scopus 로고
    • Hypoxia promotes fibrogenesis in vivo via HIF-1 stimulation of epithelial-to-mesenchymal transition
    • Higgins, D. F. et al. Hypoxia promotes fibrogenesis in vivo via HIF-1 stimulation of epithelial-to-mesenchymal transition. J. Clin. Invest. 117, 3810-3820 (2007).
    • (2007) J. Clin. Invest. , vol.117 , pp. 3810-3820
    • Higgins, D.F.1
  • 26
    • 0037098860 scopus 로고    scopus 로고
    • 165b, an inhibitory splice variant of vascular endothelial growth factor, is down-regulated in renal cell carcinoma
    • 165b, an inhibitory splice variant of vascular endothelial growth factor, is down-regulated in renal cell carcinoma. Cancer Res. 62, 4123-4131 (2002).
    • (2002) Cancer Res. , vol.62 , pp. 4123-4131
    • Bates, D.O.1
  • 27
    • 79961031252 scopus 로고    scopus 로고
    • 165b, an inhibitory splice variant of vascular endothelial growth factor leads to insufficient angiogenesis in patients with systemic sclerosis
    • 165b, an inhibitory splice variant of vascular endothelial growth factor leads to insufficient angiogenesis in patients with systemic sclerosis. Circ. Res. 109, e14-e26 (2011).
    • (2011) Circ. Res. , vol.109
    • Manetti, M.1
  • 28
    • 78049424494 scopus 로고    scopus 로고
    • Hypoxia-induced microRNA-424 expression in human endothelial cells regulates HIF-α isoforms and promotes angiogenesis
    • Ghosh, G. et al. Hypoxia-induced microRNA-424 expression in human endothelial cells regulates HIF-α isoforms and promotes angiogenesis. J. Clin. Invest. 120, 4141-4154 (2010).
    • (2010) J. Clin. Invest. , vol.120 , pp. 4141-4154
    • Ghosh, G.1
  • 29
    • 77955384669 scopus 로고    scopus 로고
    • MicroRNA-132-mediated loss of p120RasGAP activates the endothelium to facilitate pathological angigogenesis
    • Anand, S. et al. MicroRNA-132-mediated loss of p120RasGAP activates the endothelium to facilitate pathological angigogenesis. Nat. Med. 16, 909-914 (2010).
    • (2010) Nat. Med. , vol.16 , pp. 909-914
    • Anand, S.1
  • 30
    • 78650270964 scopus 로고    scopus 로고
    • Beyond genetics: Epigenetic code in chronic kidney disease
    • Dwivedi, R. S., Herman, J. G., McCaffrey, T. A. & Raj, D. S. Beyond genetics: epigenetic code in chronic kidney disease. Kidney Int. 79, 23-32 (2011).
    • (2011) Kidney Int. , vol.79 , pp. 23-32
    • Dwivedi, R.S.1    Herman, J.G.2    McCaffrey, T.A.3    Raj, D.S.4
  • 31
    • 77957607057 scopus 로고    scopus 로고
    • Endothelial cells dynamically compete for the tip cell position during angiogenic sprouting
    • Jakobsson, L. et al. Endothelial cells dynamically compete for the tip cell position during angiogenic sprouting. Nat. Cell. Biol. 12, 943-953 (2010).
    • (2010) Nat. Cell. Biol. , vol.12 , pp. 943-953
    • Jakobsson, L.1
  • 32
    • 79951816985 scopus 로고    scopus 로고
    • Targeting endothelium-pericyte cross talk by inhibiting VEGF receptor signaling attenuates kidney microvascular rarefaction and fibrosis
    • Lin, S. L. et al. Targeting endothelium-pericyte cross talk by inhibiting VEGF receptor signaling attenuates kidney microvascular rarefaction and fibrosis. Am. J. Pathol. 178, 911-923 (2011).
    • (2011) Am. J. Pathol. , vol.178 , pp. 911-923
    • Lin, S.L.1
  • 34
    • 51849154952 scopus 로고    scopus 로고
    • Kidney-derived mesenchymal stem cells contribute to vasculogenesis, angiogenesis and endothelial repair
    • Chen, J. et al. Kidney-derived mesenchymal stem cells contribute to vasculogenesis, angiogenesis and endothelial repair. Kidney Int. 74, 879-889 (2008).
    • (2008) Kidney Int. , vol.74 , pp. 879-889
    • Chen, J.1
  • 35
    • 13244251415 scopus 로고    scopus 로고
    • Isolation of renal progenitor cells from adult human kidney
    • Bussolati, B. et al. Isolation of renal progenitor cells from adult human kidney. Am. J. Pathol. 166, 545-555 (2005).
    • (2005) Am. J. Pathol. , vol.166 , pp. 545-555
    • Bussolati, B.1
  • 36
    • 77950555289 scopus 로고    scopus 로고
    • Adriamycin nephropathy, a failure of endothelial progenitor cell-induced repair
    • Yasuda, K. et al. Adriamycin nephropathy, a failure of endothelial progenitor cell-induced repair. Am. J. Pathol. 176, 1685-1695 (2010).
    • (2010) Am. J. Pathol. , vol.176 , pp. 1685-1695
    • Yasuda, K.1
  • 38
    • 77950550177 scopus 로고    scopus 로고
    • First heal thyself: Rescue of dysfunctional endothelial progenitor cells restores function to the injured kidney
    • Fine, L. G. First heal thyself: Rescue of dysfunctional endothelial progenitor cells restores function to the injured kidney. Am. J. Pathol. 176, 1586-1587 (2010).
    • (2010) Am. J. Pathol. , vol.176 , pp. 1586-1587
    • Fine, L.G.1
  • 39
    • 0031019745 scopus 로고    scopus 로고
    • Isolation of putative progenitor endothelial cells for angiogenesis
    • Asahara, T. et al. Isolation of putative progenitor endothelial cells for angiogenesis. Science 275, 964-967 (1997).
    • (1997) Science , vol.275 , pp. 964-967
    • Asahara, T.1
  • 40
    • 0036281597 scopus 로고    scopus 로고
    • Adult hematopoietic stem cells provide functional hemangioblast activity during retinal neovascularization
    • Grant, M. B. et al. Adult hematopoietic stem cells provide functional hemangioblast activity during retinal neovascularization. Nat. Med. 8, 607-612 (2002).
    • (2002) Nat. Med. , vol.8 , pp. 607-612
    • Grant, M.B.1
  • 41
    • 51649099800 scopus 로고    scopus 로고
    • Assessing identity, phenotype, and fate of endothelial progenitor cells
    • Hirschi, K. K., Ingram, D. A. & Yoder, M. C. Assessing identity, phenotype, and fate of endothelial progenitor cells. Arterioscler. Thromb. Vasc. Biol. 28, 1584-1595 (2008).
    • (2008) Arterioscler. Thromb. Vasc. Biol. , vol.28 , pp. 1584-1595
    • Hirschi, K.K.1    Ingram, D.A.2    Yoder, M.C.3
  • 42
    • 77953003805 scopus 로고    scopus 로고
    • Dysfunctional endothelial progenitor cells in chronic kidney disease
    • Goligorsky, M. S., Yasuda, K. & Ratliff, B. Dysfunctional endothelial progenitor cells in chronic kidney disease. J. Am. Soc. Nephrol. 21, 911-919 (2010).
    • (2010) J. Am. Soc. Nephrol. , vol.21 , pp. 911-919
    • Goligorsky, M.S.1    Yasuda, K.2    Ratliff, B.3
  • 43
    • 17744387942 scopus 로고    scopus 로고
    • Renal SDF-1 signals mobilization and homing of CXCR4-positive cells to the kidney after ischemic injury
    • Togel, F., Issac, J., Hu, Z., Weiss, K. & Westernfelder, C. Renal SDF-1 signals mobilization and homing of CXCR4-positive cells to the kidney after ischemic injury. Kidney Int. 67, 1772-1784 (2005).
    • (2005) Kidney Int. , vol.67 , pp. 1772-1784
    • Togel, F.1    Issac, J.2    Hu, Z.3    Weiss, K.4    Westernfelder, C.5
  • 44
    • 77956644660 scopus 로고    scopus 로고
    • Endothelial progenitor cells homing and renal repair in experimental renovascular disease
    • Chade, A. R. et al. Endothelial progenitor cells homing and renal repair in experimental renovascular disease. Stem Cells 28, 1039-1047 (2010).
    • (2010) Stem Cells , vol.28 , pp. 1039-1047
    • Chade, A.R.1
  • 45
    • 84856004957 scopus 로고    scopus 로고
    • Enhanced endothelial progenitor cell angiogenic potency, present in early experimental renovascular hypertension, deteriorates with disease duration
    • Zhu, X. Y. et al. Enhanced endothelial progenitor cell angiogenic potency, present in early experimental renovascular hypertension, deteriorates with disease duration. J. Hypertens. 29, 1972-1979 (2011).
    • (2011) J. Hypertens. , vol.29 , pp. 1972-1979
    • Zhu, X.Y.1
  • 46
    • 66449132290 scopus 로고    scopus 로고
    • Endothelial progenitor cell dysfunction in patients with progressive chronic kidney disease
    • Krenning, G. et al. Endothelial progenitor cell dysfunction in patients with progressive chronic kidney disease. Am. J. Physiol. Renal Physiol. 296, F1314-F1322 (2009).
    • (2009) Am. J. Physiol. Renal Physiol. , vol.296
    • Krenning, G.1
  • 47
    • 77955404777 scopus 로고    scopus 로고
    • Bone marrow-derived endothelial progenitor cells confer renal protection in a murine chronic renal failure model
    • Sangidorj, O. et al. Bone marrow-derived endothelial progenitor cells confer renal protection in a murine chronic renal failure model. Am. J. Physiol. Renal Physiol. 299, F325-F335 (2010).
    • (2010) Am. J. Physiol. Renal Physiol. , vol.299
    • Sangidorj, O.1
  • 48
    • 61349167743 scopus 로고    scopus 로고
    • Endothelial progenitor cells restore renal function in chronic experimental renovascular disease
    • Chade, A. R. et al. Endothelial progenitor cells restore renal function in chronic experimental renovascular disease. Circulation 119, 547-557 (2009).
    • (2009) Circulation , vol.119 , pp. 547-557
    • Chade, A.R.1
  • 49
    • 78650018824 scopus 로고    scopus 로고
    • Conversion of vascular endothelial cells into multipotent stem-like cells
    • Medici, D. et al. Conversion of vascular endothelial cells into multipotent stem-like cells. Nat. Med. 16, 1400-1406 (2010).
    • (2010) Nat. Med. , vol.16 , pp. 1400-1406
    • Medici, D.1
  • 50
    • 77952241187 scopus 로고    scopus 로고
    • Mechanism of improved cardiac function after bone marrow mononuclear cell therapy: Role of cardiovascular lineage commitment
    • Yoon, C.-H. et al. Mechanism of improved cardiac function after bone marrow mononuclear cell therapy: role of cardiovascular lineage commitment. Circulation 121, 2001-2011 (2010).
    • (2010) Circulation , vol.121 , pp. 2001-2011
    • Yoon, C.-H.1
  • 51
    • 63949084807 scopus 로고    scopus 로고
    • Lymphatic vessels develop during tubulointerstitial fibrosis
    • Sakamoto, I. et al. Lymphatic vessels develop during tubulointerstitial fibrosis. Kidney Int. 75, 828-838 (2009).
    • (2009) Kidney Int. , vol.75 , pp. 828-838
    • Sakamoto, I.1
  • 52
    • 0041342011 scopus 로고    scopus 로고
    • Lymphatic microvessels in the rat remnant kidney model of renal fibrosis: Aminopeptidase p and podoplanin are discriminatory markers for endothelial cells of blood and lymphatic vessels
    • Matsui, K. et al. Lymphatic microvessels in the rat remnant kidney model of renal fibrosis: aminopeptidase p and podoplanin are discriminatory markers for endothelial cells of blood and lymphatic vessels. J. Am. Soc. Nephrol. 14, 1981-1989 (2003).
    • (2003) J. Am. Soc. Nephrol. , vol.14 , pp. 1981-1989
    • Matsui, K.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.