Noncanonical control of C. elegans germline apoptosis by the insulin-IGF-1 and Ras-MAPK signaling pathways

Cell Death and Differentiation

Volumn 20, Issue 1, 2013, Pages 97-107

  Perrin, A J ^a,b   Gunda, M ^a   Yu, B ^a   Yen, K ^c   Ito, S ^a,b   Forster, S ^a   Tissenbaum, H A ^c   Derry, W B ^a,b  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

apoptosis; C. elegans; DNA damage; PI3K; Ras

Indexed keywords

AKT 1 PROTEIN; CEP 1 PROTEIN; DAF 2 PROTEIN; INSULIN; MITOGEN ACTIVATED PROTEIN KINASE; PDK 1 PROTEIN; PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE 1; PROTEIN; PROTEIN KINASE B; RAS PROTEIN; RECEPTOR; SERINE; SOMATOMEDIN C; THREONINE; TRANSCRIPTION FACTOR DAF 16; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; DNA DAMAGE; GAIN OF FUNCTION MUTATION; GERM CELL; GERM LINE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RADIATION DOSE; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; WILD TYPE;

ANIMALS; APOPTOSIS; CAENORHABDITIS ELEGANS; DNA DAMAGE; INSULIN; INSULIN-LIKE GROWTH FACTOR I; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RAS PROTEINS;

CAENORHABDITIS ELEGANS;

EID: 84871011838     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2012.101     Document Type: Article

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