Inhibitors of HIV-1 attachment. Part 11: The discovery and structure-activity relationships associated with 4,6-diazaindole cores

Bioorganic and Medicinal Chemistry Letters

Volumn 23, Issue 1, 2013, Pages 218-222

  Bender, John A ^a   Yang, Zhong ^a   Eggers, Betsy ^a   Gong, Yi Fei ^a   Lin, Pin Fang ^a   Parker, Dawn D ^a   Rahematpura, Sandhya ^a   Zheng, Ming ^a   Meanwell, Nicholas A ^a   Kadow, John F ^a  

^a BRISTOL MYERS SQUIBB   (United States)

Author keywords

4,6 Diazaindole; Attachment; BMS 488043; Entry; HIV 1

Indexed keywords

1 BENZOYL 4 [(4,7 DIMETHOXY 1H PYRROLO[2,3 C]PYRIDIN 3 YL)OXOACETYL]PIPERAZINE; 4 BENZOYL 1 [(4 METHOXY 1H PYRROLO[2,3 B]PYRIDIN 3 YL)OXOACETYL] 2 METHYLPIPERAZINE; 4,6 DIAZAINDOLE; HUMAN IMMUNODEFICIENCY VIRUS ANTIBODY; INDOLE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; DRUG CLEARANCE; DRUG EFFICACY; DRUG POTENCY; FAT INTAKE; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; RAT; SINGLE DRUG DOSE; STRUCTURE ACTIVITY RELATION;

ADMINISTRATION, ORAL; ANIMALS; ANTI-HIV AGENTS; AZA COMPOUNDS; DRUG EVALUATION, PRECLINICAL; HALF-LIFE; HIV-1; HUMANS; INDOLES; PIPERAZINES; RATS; STRUCTURE-ACTIVITY RELATIONSHIP; VIRUS ATTACHMENT;

HUMAN IMMUNODEFICIENCY VIRUS 1; RATTUS;

EID: 84870986229     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2012.10.118     Document Type: Article

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