A short, facile synthesis of 2-amino-1,5-dihydro-4H-pyrrolo[3,2-d]-pyrimidin-4-one (9-deazaguanine)

Tetrahedron Letters

Volumn 37, Issue 25, 1996, Pages 4339-4340

  Elliott, Arthur J ^a   Montgomery, John A ^a   Walsh, David A ^a  

^a BIOCRYST PHARMACEUTICALS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

9 DEAZAGUANOSINE; GUANINE DERIVATIVE; PELDESINE; PURINE NUCLEOSIDE PHOSPHORYLASE; UNCLASSIFIED DRUG;

ARTICLE; CYCLIZATION; DECARBOXYLATION; DRUG SYNTHESIS;

EID: 0029933816     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/0040-4039(96)00840-4     Document Type: Article

References (8)

1. (a) Montgomery, J. A.; Niwas, S.; Rose, J. D.; Secrist III, J. A.; Babu, Y. S.; Bugg, C. E.; Erion, M. D.; Guida, W. C.; Ealick, S. E. J. Med. Chem. 1993, 36, 55-69.
2. (b) Montgomery, J. A.; Snyder Jr., H. W.; Walsh, D. A.; Walsh, G. M. Drugs Future 1993, 18, 887-890.
3. (a) Tanaka, K.; Sugawa, T.; Nakamori, R; Sanno, Y.; Ando, Y.; Imai, K.-I. Chem. Pharm. Bull. 1964, 12, 1024-1030.
4. (b) Imai, K.-I. Chem. Pharm. Bull. 1964, 12, 1030-1042.
5. Kline, R. S.; Lim, M.-I.; Tam, S. Y.-K.; Fox, J. J. J. Org. Chem. 1978, 43, 2536-2539.
6. Taylor, E. C.; Young, W. B.; Ward, C. C. Tetrahedron Lett. 1993, 34, 4595-4598.
7. Kruse, L. I.; Ladd, D. L.; Harrsch, P. B.; McCabe, F. L.; Mong, S.-M.; Faucette, L.; Johnson, R. J. Med. Chem. 1989, 32, 409-417.
8. Kim, K. S.; Qian, L. Tetrahedron Lett. 1993, 34, 7677-7680.