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Bioorganic and Medicinal Chemistry Letters

Volumn 23, Issue 1, 2013, Pages 163-168

Hybrid fluorescent conjugates of COX-2 inhibitors: Search for a COX-2 isozyme imaging cancer biomarker

(6) Bhardwaj, Atul a Kaur, Jatinder a Sharma, Sai Kiran a Huang, Zhangjian a Wuest, Frank a Knaus, Edward E a

a UNIVERSITY OF ALBERTA (Canada)

Author keywords

Cyclooxygenase; Enzymes; Fluorescent imaging; Inhibitors; Non steroidal anti inflammatory drugs

Indexed keywords

ACETYLSALICYLIC ACID; ACRIDONE DERIVATIVE; BIOLOGICAL MARKER; CELECOXIB; CHLOROROFECOXIB; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; DANSYL CHLORIDE; IBUPROFEN; NAPROXEN; NONSTEROID ANTIINFLAMMATORY AGENT; RHODAMINE B; ROFECOXIB; UNCLASSIFIED DRUG;

ARTICLE; AUTOFLUORESCENCE IMAGING; CANCER CELL; CANCER CELL CULTURE; COLON CANCER; CONTROLLED STUDY; CROSS COUPLING REACTION; DRUG CONJUGATION; DRUG POTENCY; DRUG SELECTIVITY; DRUG SYNTHESIS; FIELD EMISSION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; NEOPLASM;

ACRIDINES; CELL LINE, TUMOR; COLONIC NEOPLASMS; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; FLUORESCENT DYES; HUMANS; IBUPROFEN; MICROSCOPY, CONFOCAL; PROTEIN BINDING; PYRAZOLES; RHODAMINES; STRUCTURE-ACTIVITY RELATIONSHIP; SULFONAMIDES; TUMOR MARKERS, BIOLOGICAL;

EID: 84870983134 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2012.10.131 Document Type: Article

Times cited : (37)

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