SCOPUS 정보 검색 플랫폼

Volumn 7, Issue 1, 2012, Pages 62-67

Rofecoxib analogues possessing a nitric oxide donor sulfohydroxamic acid (SO 2NHOH) cyclooxygenase-2 pharmacophore: Synthesis, molecular modeling, and biological evaluation as anti-inflammatory agents

(4) Bhardwaj, Atul a Huang, Zhangjian a Kaur, Jatinder a Knaus, Edward E a

a UNIVERSITY OF ALBERTA (Canada)

Author keywords

Biological activity; Cyclooxygenases; Drug design; Inflammation; Inhibitors

Indexed keywords

ANTIINFLAMMATORY AGENT; CELECOXIB; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; N HYDROXY 4 (5 OXO 4 PHENYL 2,5 DIHYDROFURAN 3 YL)BENZENESULFONAMIDE; N HYDROXY 4 [4 (4 CHLOROPHENYL) 5 OXO 2,5 DIHYDROFURAN 3 YL] BENZENESULFONAMIDE; N HYDROXY 4[4 (4 FLUOROPHENYL) 5 OXO 2,5 DIHYDROFURAN 3 YL] BENZENESULFONAMIDE; N METHOXY 4 [4 (4 FLUOROPHENYL) 5 OXO 2,5 DIHYDROFURAN 3 YL] BENZENESULFONAMIDE; NITRIC OXIDE; ROFECOXIB; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG SYNTHESIS; ENZYME INHIBITION; MALE; MOLECULAR DOCKING; MOLECULAR MODEL; NONHUMAN; PAW EDEMA; PHARMACOPHORE; PRIORITY JOURNAL; RAT; SULFONATION;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; DRUG DESIGN; HUMANS; HYDROXAMIC ACIDS; LACTONES; MALE; MODELS, MOLECULAR; NITRIC OXIDE; NITRIC OXIDE DONORS; RATS; RATS, SPRAGUE-DAWLEY; SULFONES;

EID: 84555177680 PISSN: 18607179 EISSN: 18607187 Source Type: Journal
DOI: 10.1002/cmdc.201100393 Document Type: Article

Times cited : (27)

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