The catalytic competence of cytochrome P450 in the synthesis of serotonin from 5-methoxytryptamine in the brain: An in vitro study

Pharmacological Research

Volumn 67, Issue 1, 2013, Pages 53-59

  Haduch, Anna ^a   Bromek, Ewa ^a   Sadakierska Chudy, Anna ^a   Wójcikowski, Jacek ^a   Daniel, Władysława A ^a  

^a INSTITUTE OF PHARMACOLOGY   (Poland)

Author keywords

5 Methoxytryptamine O demethylation; Cytochrome P450 isoforms; In vitro study; Rat and human liver microsomes; Rat brain microsomes; Serotonin synthesis

Indexed keywords

COMPLEMENTARY DNA; CYTOCHROME P450; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; CYTOCHROME P450 2A1; CYTOCHROME P450 2A2; CYTOCHROME P450 2B1; CYTOCHROME P450 2C6; CYTOCHROME P450 2D1; CYTOCHROME P450 2D6; CYTOCHROME P450 2E1; CYTOCHROME P450 3A2; FLUOXETINE; QUININE; SEROTONIN; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BRAIN MICROSOME; CATALYSIS; CONTROLLED STUDY; DEMETHYLATION; DRUG EFFECT; HUMAN; HUMAN CELL; IN VITRO STUDY; INHIBITION KINETICS; LIVER MICROSOME; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SEROTONIN METABOLISM; SYNTHESIS; WILD TYPE;

5-METHOXYTRYPTAMINE; ANIMALS; BRAIN; CATALYSIS; CYTOCHROME P-450 ENZYME SYSTEM; HUMANS; MALE; MICROSOMES; RATS; RATS, WISTAR; SEROTONIN;

EID: 84870915350     PISSN: 10436618     EISSN: 10961186     Source Type: Journal    
DOI: 10.1016/j.phrs.2012.10.009     Document Type: Article

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