-
1
-
-
0029050430
-
Frequency of a specific cytochrome P4502D6B (CYP2D6B) mutant allele in clinically differentiated groups of patients with Parkinson disease
-
Akhmedova S. N., Pushinova E. A., Yakimovsky A. F., Avtonomov V. V., and, Schwarz E. I., (1995) Frequency of a specific cytochrome P4502D6B (CYP2D6B) mutant allele in clinically differentiated groups of patients with Parkinson disease. Biochem. Mol. Med. 54, 88-90.
-
(1995)
Biochem. Mol. Med.
, vol.54
, pp. 88-90
-
-
Akhmedova, S.N.1
Pushinova, E.A.2
Yakimovsky, A.F.3
Avtonomov, V.V.4
Schwarz, E.I.5
-
2
-
-
4644357712
-
Cigarette smoking in Parkinson's disease: Influence on disease progression
-
DOI 10.1002/mds.20117
-
Alves G., Kurz M., and, Larsen J. P., (2004) Cigarette smoking in Parkinson's disease: influence on disease progression. Mov. Disord. 19, 1087-1092. (Pubitemid 39302846)
-
(2004)
Movement Disorders
, vol.19
, Issue.9
, pp. 1087-1092
-
-
Alves, G.1
Kurz, M.2
Lie, S.A.3
Larsen, J.P.4
-
3
-
-
0032918986
-
CYP2D6 is associated with Parkinson's disease but not with dementia with Lewy Bodies or Alzheimer's disease
-
Atkinson A., Singleton A. B., Steward A., Ince P. G., Ferry R. H., McKeith I. G., Fairbairn A. F., Edwardson J. A., Daly A. K., and, Morris C. M., (1999) CYP2D6 is associated with Parkinson's disease but not with dementis with Lewy Bodies or Alzheimer's disease. Pharmacogenetics 9, 31-35. (Pubitemid 29176721)
-
(1999)
Pharmacogenetics
, vol.9
, Issue.1
, pp. 31-35
-
-
Atkinson, A.1
Singleton, A.B.2
Steward, A.3
Ince, P.G.4
Perry, R.H.5
McKeith, I.G.6
Fairbairn, A.F.7
Edwardson, J.A.8
Daly, A.K.9
Morris, C.M.10
-
4
-
-
0030858099
-
Regulation of expression of cytochrome P-450 2D mRNA in rat brain with steroid hormones
-
DOI 10.1016/S0006-8993(97)00428-9, PII S0006899397004289
-
Baum L. O., and, Strobel H. W., (1997) Regulation of expression of cytochrome P-450 2D mRNA in rat brain with steroid hormones. Brain Res. 765, 67-73. (Pubitemid 27374915)
-
(1997)
Brain Research
, vol.765
, Issue.1
, pp. 67-73
-
-
Baum, L.O.1
Strobel, H.W.2
-
5
-
-
0011578981
-
Debrisoquine hydroxylation polymorphism and personality
-
Bertilsson L., Alm C., De Las Carreras C., Widen J., Edman G., and, Schalling D., (1989) Debrisoquine hydroxylation polymorphism and personality. Lancet 1, 555. (Pubitemid 19075230)
-
(1989)
Lancet
, vol.1
, Issue.8637
, pp. 555
-
-
Bertilsson, L.1
Alm, C.2
De Las Carreras, C.3
Widen, J.4
Edman, G.5
Schalling, D.6
-
6
-
-
0000022434
-
Occurrence and distribution of catechol amines in brain
-
Bertler A., and, Rosengren E., (1959) Occurrence and distribution of catechol amines in brain. Acta Physiol. Scand. 47, 350-361.
-
(1959)
Acta Physiol. Scand.
, vol.47
, pp. 350-361
-
-
Bertler, A.1
Rosengren, E.2
-
7
-
-
16944362939
-
Dopaminergic neurons intrinsic to the primate striatum
-
Betarbet R., Turner R., Chockkan V., DeLong M. R., Allers K. A., Walters J., Levey A. I., and, Greenamyre J. T., (1997) Dopaminergic neurons intrinsic to the primate striatum. J. Neurosci. 17, 6761-6768. (Pubitemid 27366627)
-
(1997)
Journal of Neuroscience
, vol.17
, Issue.17
, pp. 6761-6768
-
-
Greenamyre, J.T.1
-
8
-
-
0017249479
-
Identification, distribution, metabolism, and function of meta and para tyramine, phenylethylamine and tryptamine in brain
-
Boulton A. A., (1976) Identification, distribution, metabolism, and function of meta and para tyramine, phenylethylamine and tryptamine in brain. Adv. Biochem. Psychopharmacol. 15, 57-67.
-
(1976)
Adv. Biochem. Psychopharmacol.
, vol.15
, pp. 57-67
-
-
Boulton, A.A.1
-
9
-
-
0017363726
-
The effects of reserpine and 6 hydroxydopamine on the concentrations of some arylalkylamines in rat brain
-
Boulton A. A., Juorio A. V., Philips S. R., and, Wu P. H., (1977) The effects of reserpine and 6-hydroxydopamine on the concentrations of some arylakylamines in rat brain. Br. J. Pharmacol. 59, 209-214. (Pubitemid 8015161)
-
(1977)
British Journal of Pharmacology
, vol.59
, Issue.1
, pp. 209-214
-
-
Boulton, A.A.1
Juorio, A.V.2
Philips, S.R.3
Wu, P.H.4
-
10
-
-
70749145658
-
The ability of cytochrome P450 2D forms to synthesize dopamine in the brain: An in vitro study
-
Bromek E., Haduch A., and, Daniel W. A., (2010) The ability of cytochrome P450 2D forms to synthesize dopamine in the brain: an in vitro study. Eur. J. Pharmacol. 626, 171-178.
-
(2010)
Eur. J. Pharmacol.
, vol.626
, pp. 171-178
-
-
Bromek, E.1
Haduch, A.2
Daniel, W.A.3
-
11
-
-
0037198965
-
Constitutive expression and localization of the major drug metabolizing enzyme, cytochrome P4502D in human brain
-
DOI 10.1016/S0169-328X(02)00177-8, PII S0169328X02001778
-
Chinta S. J., Pal H. V., Upadhya S. C., Boyd M. R., and, Ravindranath V., (2002) Constitutive expression and localization of the major drug metabolizing enzyme, cytochrome P4502D in human brain. Brain Res. Mol. Brain Res. 103, 49-61. (Pubitemid 34775033)
-
(2002)
Molecular Brain Research
, vol.103
, Issue.1-2
, pp. 49-61
-
-
Chinta, S.J.1
Pai, H.V.2
Upadhya, S.C.3
Boyd, M.R.4
Ravindranath, V.5
-
12
-
-
0001989279
-
Evidence for the existence of monoamine neurons in the central nervous system
-
(Suppl. 247)
-
Dahlström A., and, Fuxe K., (1965) Evidence for the existence of monoamine neurons in the central nervous system. Acta Physiol. Scand. 64 (Suppl. 247), 1-85.
-
(1965)
Acta Physiol. Scand.
, vol.64
, pp. 1-85
-
-
Dahlström, A.1
Fuxe, K.2
-
13
-
-
0037307139
-
Mechanisms of cellular distribution of psychotropic drugs. Significance for drug action and interactions
-
DOI 10.1016/S0278-5846(02)00317-2, PII S0278584602003172
-
Daniel W. A., (2003) Mechanisms of cellular distribution of psychotropic drugs. Significance of drug action and interactions. Prog. Neuropsychopharmacol. Biol. Psychiatry 27, 65-73. (Pubitemid 36126648)
-
(2003)
Progress in Neuro-Psychopharmacology and Biological Psychiatry
, vol.27
, Issue.1
, pp. 65-73
-
-
Daniel, W.A.1
-
14
-
-
0034748454
-
Intracellular distribution of psychotropic drugs in the grey and white matter of the brain: The role of lysosomal trapping
-
Daniel W. A., Wõjcikowski J., and, Pałucha A., (2001) Distribution of psychotropic drugs in the grey and white matter of the brain. In vitro studies. Br. J. Pharmacol. 134, 807-814. (Pubitemid 33016152)
-
(2001)
British Journal of Pharmacology
, vol.134
, Issue.4
, pp. 807-814
-
-
Daniel, W.A.1
Wojcikowski, J.2
Palucha, A.3
-
15
-
-
0343933624
-
Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats
-
Di Chiara G., and, Imperato A., (1988) Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats. Proc. Natl Acad. Sci. USA 85, 5274-5278.
-
(1988)
Proc. Natl Acad. Sci. USA
, vol.85
, pp. 5274-5278
-
-
Di Chiara, G.1
Imperato, A.2
-
16
-
-
37349090515
-
CYP2D6 polymorphism: Implications for antipsychotic drug response, schizophrenia and personality traits
-
DOI 10.2217/14622416.8.11.1597
-
Dorado P., Peñas-Lledo E. M., and, Llerena A., (2007) CYP2D6 polymorphism: implications for antipsychotic drug response, schizophrenia and personality traits. Pharmacogenomics 8, 1597-1608. (Pubitemid 350286402)
-
(2007)
Pharmacogenomics
, vol.8
, Issue.11
, pp. 1597-1608
-
-
Dorado, P.1
Penas-Lledo, E.M.2
Llerena, A.3
-
17
-
-
39149106106
-
Xenobiotic metabolizing enzymes in the central nervous system: Contribution of cytochrome P450 enzymes in normal and pathological human brain
-
Dutheil F., Beaune P., and, Loriot M.-A., (2008) Xenobiotic metabolizing enzymes in the central nervous system: contribution of cytochrome P450 enzymes in normal and pathological human brain. Biochimie 90, 426-436.
-
(2008)
Biochimie
, vol.90
, pp. 426-436
-
-
Dutheil, F.1
Beaune, P.2
Loriot, M.-A.3
-
18
-
-
67649392372
-
Xenobiotic-metabolizing enzymes and transporters in the central in the normal human brain: Regional and cellular mapping as a basis for putative roles in cerebral function
-
Dutheil F., Dauchy S., Diry M., et al. (2009) Xenobiotic-metabolizing enzymes and transporters in the central in the normal human brain: regional and cellular mapping as a basis for putative roles in cerebral function. Drug Metab. Dispos. 37, 1528-1538.
-
(2009)
Drug Metab. Dispos.
, vol.37
, pp. 1528-1538
-
-
Dutheil, F.1
Dauchy, S.2
Diry, M.3
-
19
-
-
0024322129
-
Release of some endogenous trace amines from rat striatal slices in the presence and absence of a monoamine oxidase inhibitor
-
DOI 10.1016/0024-3205(89)90309-3
-
Dyck L. E., (1989) Release of some endogenous trace amines from rat striatal slices in the presence and absence of a monoamine oxidase inhibitor. Life Sci. 44, 1149-1156. (Pubitemid 19152004)
-
(1989)
Life Sciences
, vol.44
, Issue.17
, pp. 1149-1156
-
-
Dyck, L.E.1
-
20
-
-
0029692278
-
Changes in dopaminergic neurons of the mesocorticolimbic system in Parkinson's disease
-
Dymecki J., Lechowicz W., Bertrand E., and, Szpak G. M., (1996) Changes in dopaminergic neurons of the mesocorticolimbic system in Parkinson's disease. Folia Neuropathol. 43, 102-106. (Pubitemid 126504543)
-
(1996)
Folia Neuropathologica
, vol.34
, Issue.2
, pp. 102-106
-
-
Dymecki, J.1
Lechowicz, W.2
Bertrand, E.3
Szpak, G.M.4
-
21
-
-
34250928307
-
Verteilung von Noradrenalin und Dopamin (3-Hydroxytyramin) im Gehirn des Menschen und Verhalten bei Erkrankungen des extrapyramidalen Systems
-
Ehringer H., and, Hornykiewicz O., (1960) Verteilung von Noradrenalin und Dopamin (3-Hydroxytyramin) im Gehirn des Menschen und Verhalten bei Erkrankungen des extrapyramidalen Systems. Klin. Wochenschrift 38, 1236-1239.
-
(1960)
Klin. Wochenschrift
, vol.38
, pp. 1236-1239
-
-
Ehringer, H.1
Hornykiewicz, O.2
-
22
-
-
0030670231
-
Substantial production of Dopamine in the human gastrointestinal tract
-
Eisenhofer G., Aneman A., Friberg P., Hooper D., FÃ¥ndriks L., Lonroth H., Hunyady B., and, Mezey E., (1997) Substantial production of dopamine in the human gastrointestinal tract. J. Clin. Endocrinol. Metab. 82, 3864-3871. (Pubitemid 27509384)
-
(1997)
Journal of Clinical Endocrinology and Metabolism
, vol.82
, Issue.11
, pp. 3864-3871
-
-
Eisenhofer, G.1
Aneman, A.2
Friberg, P.3
Hooper, D.4
Fandriks, L.5
Lonroth, H.6
Hunyady, B.7
Mezey, E.8
-
23
-
-
27644454882
-
Neural systems of reinforcement for drug addiction: From actions to habits to compulsion
-
DOI 10.1038/nn1579, PII N1579
-
Everitt B. J., and, Robbins T. W., (2005) Neural systems of reinforcement for drug addiction: from actions to habits to compulsion. Nat. Neurosci. 8, 1481-1489. (Pubitemid 41573659)
-
(2005)
Nature Neuroscience
, vol.8
, Issue.11
, pp. 1481-1489
-
-
Everitt, B.J.1
Robbins, T.W.2
-
24
-
-
0036460446
-
Acute and long-term changes in the mesolimbic dopamine pathway after systemic or local single nicotine injections
-
DOI 10.1046/j.1460-9568.2001.02009.x
-
Ferrari R., Le Novère N., Picciotto M. R., Changeux J. P., and, Zoll M., (2001) Acute and long-term changes in the mesolimbic dopamine pathway after systemic or local single nicotine injections. Eur. J. Neurosci. 15, 1810-1818. (Pubitemid 35471906)
-
(2002)
European Journal of Neuroscience
, vol.15
, Issue.11
, pp. 1810-1818
-
-
Ferrari, R.1
Le Novere, N.2
Picciotto, M.R.3
Changeux, J.P.4
Zoli, M.5
-
25
-
-
0033842094
-
Smoking and Parkinson's and Alzheimer's disease: Review of the epidemiological studies
-
DOI 10.1016/S0166-4328(00)00206-0, PII S0166432800002060
-
Fratiglioni L., and, Wang H. X., (2000) Smoking and Parkinson's and Alzheimer's disease: review of the epidemiological studies. Behav. Brain Res. 113, 117-120. (Pubitemid 30645549)
-
(2000)
Behavioural Brain Research
, vol.113
, Issue.1-2
, pp. 117-120
-
-
Fratiglioni, L.1
Wang, H.-X.2
-
26
-
-
4644314162
-
CYP2D in the brain
-
Funae Y., Kishimoto W., Cho T., Niwa T., and, Hiroi T., (2003) CYP2D in the brain. Drug Metab. Pharmacokin. 18, 337-349.
-
(2003)
Drug Metab. Pharmacokin.
, vol.18
, pp. 337-349
-
-
Funae, Y.1
Kishimoto, W.2
Cho, T.3
Niwa, T.4
Hiroi, T.5
-
27
-
-
49349111331
-
Paradoxical effects of adenosine receptor ligands on hydroxyl radical generation by L-DOPA in the rat striatum
-
Gołembiowska K., Dziubina A., Kowalska M., and, Kamińska K., (2008) Paradoxical effects of adenosine receptor ligands on hydroxyl radical generation by L-DOPA in the rat striatum. Pharmacol. Rep. 60, 319-330.
-
(2008)
Pharmacol. Rep.
, vol.60
, pp. 319-330
-
-
Gołembiowska, K.1
Dziubina, A.2
Kowalska, M.3
Kamińska, K.4
-
28
-
-
49949118071
-
Relation between CYP2D6 phenotype and genotype and personality in healthy volunteers
-
González I., Peñas-Lledo E. M., Pérez B., Dorado P., Alvarez M., and, Llerena A., (2008) Relation between CYP2D6 phenotype and genotype and personality in healthy volunteers. Pharmacogenomics 9, 833-840.
-
(2008)
Pharmacogenomics
, vol.9
, pp. 833-840
-
-
González, I.1
Peñas-Lledo, E.M.2
Pérez, B.3
Dorado, P.4
Alvarez, M.5
Llerena, A.6
-
29
-
-
78650677482
-
The effect of psychotropic drugs on cytochrome P450 2D (CYP2D) in rat brain
-
Haduch A., Bromek E., and, Daniel W. A., (2011) The effect of psychotropic drugs on cytochrome P450 2D (CYP2D) in rat brain. Eur. J. Pharmacol. 651, 51-58.
-
(2011)
Eur. J. Pharmacol.
, vol.651
, pp. 51-58
-
-
Haduch, A.1
Bromek, E.2
Daniel, W.A.3
-
30
-
-
0029788829
-
Cytochrome P4502D4 in the brain: Specific neuronal regulation by clozapine and toluene
-
Hedlund E., Wyss A., Kainu T., Backlund M., Köhler C., Pelto-Huikko M., Gustafsson J.-Å., and, Warner M., (1996) Cytochrome P4502D4 in the Brain: specific neuronal regulation by clozapine and toluene. Mol. Pharmacol. 50, 342-350. (Pubitemid 26265139)
-
(1996)
Molecular Pharmacology
, vol.50
, Issue.2
, pp. 342-350
-
-
Hedlund, E.1
Wyss, A.2
Kainu, T.3
Backlund, M.4
Kohler, C.5
Pelto-Huikko, M.6
Gustafsson, J.-A.7
Warner, M.8
-
31
-
-
0024402663
-
Radioligands of the vesicular monoamine transporter and their use as markers of monoamine storage vesicles
-
DOI 10.1016/0006-2952(89)90082-8
-
Henry J.-P., and, Scherman D., (1989) Radioligands of the vesicular monoamine transporter and their use as markers of monoamine storage vesicles. Biochem. Pharmacol. 38, 2395-2404. (Pubitemid 19188401)
-
(1989)
Biochemical Pharmacology
, vol.38
, Issue.15
, pp. 2395-2404
-
-
Henry, J.-P.1
Scherman, D.2
-
32
-
-
0032575505
-
Dopamine formation from tyramine by CYP2D6
-
DOI 10.1006/bbrc.1998.9232
-
Hiroi T., Imaoka S., and, Funae Y., (1998) Dopamine formation from tyramine by CYP2D6. Biochem. Biophys. Res. Commun. 249, 838-843. (Pubitemid 28441925)
-
(1998)
Biochemical and Biophysical Research Communications
, vol.249
, Issue.3
, pp. 838-843
-
-
Hiroi, T.1
Imaoka, S.2
Funae, Y.3
-
33
-
-
0023263919
-
Biochemical pathophysiology of Parkinson's disease
-
Hornykiewicz O., and, Kish S. J., (1986) Biochemical pathophysiology of Parkinson's disease. Adv. Neurol. 45, 19-34.
-
(1986)
Adv. Neurol.
, vol.45
, pp. 19-34
-
-
Hornykiewicz, O.1
Kish, S.J.2
-
35
-
-
79951813290
-
CYP2D6 in the brain: Genotype effects on resting brain perfusion
-
Kirchheiner J., Seeringer A., Godoy A., Ohmle B., Maier C., Beschoner P., Sim E.-J., and, Viviani R., (2011) CYP2D6 in the brain: genotype effects on resting brain perfusion. Mol. Psychiat. 16, 333-341.
-
(2011)
Mol. Psychiat.
, vol.16
, pp. 333-341
-
-
Kirchheiner, J.1
Seeringer, A.2
Godoy, A.3
Ohmle, B.4
Maier, C.5
Beschoner, P.6
Sim, E.-J.7
Viviani, R.8
-
36
-
-
0024418697
-
The specificity of inhibition of debrisoquine 4-hydroxylase activity by quinidine and quinine in the rat is the inverse of that in man
-
DOI 10.1016/0006-2952(89)90433-4
-
Kobayashi S., Murray S., Watson D., Sesardic D., Davies D. S., and, Boobis A. R., (1989) The specificity of inhibition of debrisoquine 4-hydroxylase activity by quinidine and quinine in the rat is the inverse of that in man. Biochem. Pharmacol. 38, 2795-2799. (Pubitemid 19219839)
-
(1989)
Biochemical Pharmacology
, vol.38
, Issue.17
, pp. 2795-2799
-
-
Kobayashi, S.1
Murray, S.2
Watson, D.3
Sesardic, D.4
Davies, D.S.5
Boobis, A.R.6
-
37
-
-
0015523045
-
Regulatory properties of soluble and particulate rat brain tyrosine hydroxylase
-
Kuczenski R. T., and, Mandell A. J., (1972) Regulatory properties of soluble and particulate rat brain tyrosine hydroxylase. J. Biol. Chem. 247, 3114-3122.
-
(1972)
J. Biol. Chem.
, vol.247
, pp. 3114-3122
-
-
Kuczenski, R.T.1
Mandell, A.J.2
-
38
-
-
0027330416
-
450 CYP2D6 allelic frequencies in Parkinson's disease
-
Kurth M. C., and, Kurth J. H., (1993) Variant cytochrome P450 CYP2D6 allelic frequencies in Parkinson's disease. Am. J. Mol. Genet. 48, 166-168. (Pubitemid 23292013)
-
(1993)
American Journal of Medical Genetics
, vol.48
, Issue.3
, pp. 166-168
-
-
Kurth, M.C.1
Kurth, J.H.2
-
39
-
-
78651194643
-
The estimation of small quantities of 3,4-dihyroxyphenylethylamine in tissues
-
Laverty R., and, Sharman D. F., (1965) The estimation of small quantities of 3,4-dihyroxyphenylethylamine in tissues. Br. J. Pharmacol. 24, 538-548.
-
(1965)
Br. J. Pharmacol.
, vol.24
, pp. 538-548
-
-
Laverty, R.1
Sharman, D.F.2
-
40
-
-
0027464041
-
Relationship between personality and debrisoquine hydroxylation capacity. Suggestion of an endogenous neuroactive substrate or product of the cytochrome P4502D6
-
Llerena A., Edman G., Cobaleda J., Benitez J., Schalling D., and, Bertilsson L., (1993) Relationship between personality and debrisoquine hydroxylation capacity. Suggestion of an endogenous neuroactive substrate or product of the cytochrome P4502D6. Acta Psychiatr. Scand. 87, 23-28. (Pubitemid 23024862)
-
(1993)
Acta Psychiatrica Scandinavica
, vol.87
, Issue.1
, pp. 23-28
-
-
Llerena, A.1
Edman, G.2
Cobaleda, J.3
Benitez, J.4
Schalling, D.5
Bertilsson, L.6
-
41
-
-
77950419280
-
Cytochrome P450 2D6 enzyme neuroprotects against 1-methyl-4- phenylpyridinium toxicity in SH-SY5Y neuronal cells
-
Mann A., and, Tyndale R. F., (2010) Cytochrome P450 2D6 enzyme neuroprotects against 1-methyl-4-phenylpyridinium toxicity in SH-SY5Y neuronal cells. Eur. J. Neurosci. 31, 1185-1193.
-
(2010)
Eur. J. Neurosci.
, vol.31
, pp. 1185-1193
-
-
Mann, A.1
Tyndale, R.F.2
-
42
-
-
54049130764
-
Induction of the drug metabolizing enzyme CYP2D in monkey brain by chronic nicotine treatment
-
Mann A., Miksys S., Lee A., Mash D. C., and, Tyndale R. F., (2008) Induction of the drug metabolizing enzyme CYP2D in monkey brain by chronic nicotine treatment. Neuropharmacology 55, 1147-1155.
-
(2008)
Neuropharmacology
, vol.55
, pp. 1147-1155
-
-
Mann, A.1
Miksys, S.2
Lee, A.3
Mash, D.C.4
Tyndale, R.F.5
-
43
-
-
0031472072
-
The association between polymorphisms in the cytochrome P-450 2D6 gene and Parkinson's disease: A case-control study and meta-analysis
-
DOI 10.1016/S0022-510X(97)00179-2, PII S0022510X97001792
-
McCann S. J., Fond S. M., James K. M., and, Le Couter D. G., (1997) The association between polymorphisms in the cytochrome P-450 2D6 gene and Parkinson's disease: a case-control study and meta-analysis. J. Neurol. Sci. 153, 50-53. (Pubitemid 28010066)
-
(1997)
Journal of the Neurological Sciences
, vol.153
, Issue.1
, pp. 50-53
-
-
McCann, S.J.1
Pond, S.M.2
James, K.M.3
Le Couteur, D.G.4
-
45
-
-
3042519581
-
The unique regulation of brain cytochrome P450 2 (CYP2) family enzymes by drugs and genetics
-
DOI 10.1081/DMR-120034149
-
Miksys S., and, Tyndale R. F., (2004) The unique regulation of brain cytochrome P450 2 (CYP2) family enzymes by drugs and genetics. Drug Metab. Rev. 36, 313-333. (Pubitemid 38802491)
-
(2004)
Drug Metabolism Reviews
, vol.36
, Issue.2
, pp. 313-333
-
-
Miksys, S.1
Tyndale, R.F.2
-
46
-
-
0033947897
-
Regional and cellular distribution of CYP2D subfamily members in rat brain
-
Miksys S., Rao Y., Sellers E. M., Kwan M., Mendis D., and, Tyndale R. F., (2000) Regional and cellular distribution of CYP2D subfamily members in rat brain. Xenobiotica 30, 547-564. (Pubitemid 30449566)
-
(2000)
Xenobiotica
, vol.30
, Issue.6
, pp. 547-564
-
-
Miksys, S.1
Rao, Y.2
Sellers, E.M.3
Kwan, M.4
Mendis, D.5
Tyndale, R.F.6
-
47
-
-
0036736195
-
Regional and cellular expression of CYP2D6 in human brain: Higher levels in alcoholics
-
Miksys S., Rao Y., Hoffmann E., Mash D. C., and, Tyndale R. F., (2002) Regional and cellular expression of CYP2D6 in human brain: higher levels in alcoholics. J. Neurochem. 82, 1376-1387.
-
(2002)
J. Neurochem.
, vol.82
, pp. 1376-1387
-
-
Miksys, S.1
Rao, Y.2
Hoffmann, E.3
Mash, D.C.4
Tyndale, R.F.5
-
48
-
-
0015186836
-
Brain uptake of radiolabelled amino acids, amines and hexoses after arterial injection
-
Oldendorf W. H., (1971) Brain uptake of radiolabelled amino acids, amines and hexoses after arterial injection. Am. J. Physiol. 221, 1629-1639.
-
(1971)
Am. J. Physiol.
, vol.221
, pp. 1629-1639
-
-
Oldendorf, W.H.1
-
49
-
-
33747180080
-
Degeneration of dopaminergic mesocortical neurons and activation of compensatory processes induced by a long-term paraquat administration in rats: Implications for Parkinson's disease
-
DOI 10.1016/j.neuroscience.2006.05.039, PII S0306452206007330
-
Ossowska K., Śmiałowska M., Kuter K., et al. (2006) Degeneration of dopaminergic mesocortical neurons and activation of compensatory processes induced by a long-term paraquat administration in rats: implications for Parkinson's disease. Neuroscience 141, 2155-2165. (Pubitemid 44233146)
-
(2006)
Neuroscience
, vol.141
, Issue.4
, pp. 2155-2165
-
-
Ossowska, K.1
Smialowska, M.2
Kuter, K.3
Wieronska, J.4
Zieba, B.5
Wardas, J.6
Nowak, P.7
Dabrowska, J.8
Bortel, A.9
Biedka, I.10
Schulze, G.11
Rommelspacher, H.12
-
50
-
-
0034220321
-
New dopaminergic neurons in Parkinson's disease striatum
-
Porritt M. J., Batchelor P. E., Hughes A. J., Kalnins R., Donnan G. A., and, Howells D. W., (2000) New dopaminergic neurons in Parkinson's disease striatum. Lancet 356, 44-45. (Pubitemid 30416998)
-
(2000)
Lancet
, vol.355
, Issue.9223
, pp. 44-45
-
-
Porritt, M.J.1
Batchelor, P.E.2
Hughes, A.J.3
Kalnins, R.4
Donnan, G.A.5
Howells, D.W.6
-
51
-
-
34548134497
-
Increased uptake of quinine into the brain by inhibition of P-glycoprotein
-
DOI 10.1016/j.ejps.2007.06.007, PII S092809870700262X
-
Pussard E., Merzouk M., and, Barennes H., (2007) Increased uptake of quinine into the brain by inhibition of P-glycoprotein. Eur. J. Pharm. Sci. 32, 123-127. (Pubitemid 47299300)
-
(2007)
European Journal of Pharmaceutical Sciences
, vol.32
, Issue.2
, pp. 123-127
-
-
Pussard, E.1
Merzouk, M.2
Barennes, H.3
-
52
-
-
33748159130
-
Chronic oral nicotine treatment protects against striatal degeneration in MPTP-treated primates
-
DOI 10.1111/j.1471-4159.2006.04078.x
-
Quik M., Parameswaran N., McCallum S. E., Bordia T., Bao S., McCormack A., Kim A., Tyndale R. F., Langston J. W., and, Di Monte D. A., (2006) Chronic oral nicotine treatment protects against striatal degeneration in MPTP-treated primates. J. Neurochem. 98, 1866-1875. (Pubitemid 44313641)
-
(2006)
Journal of Neurochemistry
, vol.98
, Issue.6
, pp. 1866-1875
-
-
Quik, M.1
Parameswaran, N.2
McCallum, S.E.3
Bordia, T.4
Bao, S.5
McCormack, A.6
Kim, A.7
Tyndale, R.F.8
Langston, J.W.9
Di Monte, D.A.10
-
53
-
-
0033586335
-
Expression and localisation of CYP2D enzymes in rat basal ganglia
-
DOI 10.1016/S0006-8993(99)01113-0, PII S0006899399011130
-
Riedl A. G., Watts P. M., Edwards R. J., Schulz-Utermoehl T., Boobis A. R., Jenner P., and, Marsden C. D., (1999) Expression and localization of CYP2D enzymes in rat basal ganglia. Brain Res. 822, 175-191. (Pubitemid 29222841)
-
(1999)
Brain Research
, vol.822
, Issue.1-2
, pp. 175-191
-
-
Riedl, A.G.1
Watts, P.M.2
Edwards, R.J.3
Schulz-Utermoehl, T.4
Boobis, A.R.5
Jenner, P.6
Marsden, C.D.7
-
54
-
-
0023212368
-
The concentration of p- and m-tyramine in the rat mesolimbic system: Its regional distribution and effect of monoamine oxidase inhibition
-
DOI 10.1016/0006-8993(87)91145-0
-
Sardar A., Juorio A. V., and, Boulton A. A., (1987) The concentration of p- and m-tyramine in the rat mesolimbic system: its regional distribution and effect of monoamine oxidase inhibition. Brain Res. 412, 370-374. (Pubitemid 17091182)
-
(1987)
Brain Research
, vol.412
, Issue.2
, pp. 370-374
-
-
Sardar, A.1
Juorio, A.V.2
Boulton, A.A.3
-
55
-
-
0020578137
-
Reduction of cortical dopamine, noradrenaline, serotonin and their metabolites in Parkinson's disease
-
DOI 10.1016/0006-8993(83)90993-9
-
Scatton B., Javoy-Agid F., Rouquier L., Dubois B., and, Agid Y., (1983) Reduction of cortical dopamine, noradrenaline, serotonin and their metabolites in Parkinson's disease. Brain Res. 275, 321-328. (Pubitemid 13004530)
-
(1983)
Brain Research
, vol.275
, Issue.2
, pp. 321-328
-
-
Scatton, B.1
Javoy Agid, F.2
Rouquier, L.3
-
56
-
-
0011853367
-
Determination of hyroxytyramine (dopamine) in symphatetic nerves and ganglia. Naunyn Schmiedebergs Arch
-
Schümann H. J., (1956) Determination of hyroxytyramine (dopamine) in symphatetic nerves and ganglia. Naunyn Schmiedebergs Arch. Exp. Pathol. Pharmakol. 227, 566-573.
-
(1956)
Exp. Pathol. Pharmakol.
, vol.227
, pp. 566-573
-
-
Schümann, H.J.1
-
57
-
-
0017087966
-
Pathways linking L-phenylalanine and 2-phenylethylamine with p-tyramine in rabbit brain
-
Silkaitis R. P., and, Mosnaim A. D., (1976) Pathways linking L-phenylalanine and 2-phenylethylamine with p-tyramine in rabbit brain. Brain Res. 114, 105-115.
-
(1976)
Brain Res.
, vol.114
, pp. 105-115
-
-
Silkaitis, R.P.1
Mosnaim, A.D.2
-
58
-
-
70349250528
-
The expression of CYP2D22, an ortholog of human CYP2D6, in mouse striatum and its modulation in 1-methyl 4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease phenotype and nicotine-mediated neuroprotection
-
Singh S., Singh K., Patel D. K., Singh C., Nath C., Singh V. K., Singh R. K., and, Singh M. P., (2009) The expression of CYP2D22, an ortholog of human CYP2D6, in mouse striatum and its modulation in 1-methyl 4-phenyl-1,2,3,6- tetrahydropyridine-induced Parkinson's disease phenotype and nicotine-mediated neuroprotection. Rejuvenation Res. 12, 185-197.
-
(2009)
Rejuvenation Res.
, vol.12
, pp. 185-197
-
-
Singh, S.1
Singh, K.2
Patel, D.K.3
Singh, C.4
Nath, C.5
Singh, V.K.6
Singh, R.K.7
Singh, M.P.8
-
59
-
-
0021848568
-
Effect of pyridoxine deficiency on aromatic L-amino acid decarboxylase in adult rat brain
-
Siow Y. L., and, Dakshinamurti K., (1985) Effect of pyridoxine deficiency on aromatic L-amino acid decarboxylase in adult rat brain. Exp. Brain Res. 59, 575-581. (Pubitemid 15042257)
-
(1985)
Experimental Brain Research
, vol.59
, Issue.3
, pp. 575-581
-
-
Siow, Y.L.1
Dakshinamurti, K.2
-
60
-
-
0033734942
-
Genotyping of CYP2D6 in Parkinson's disease
-
Stefanović M., Topić E., Ivanisević A. M., Relja M., and, Korsić M., (2000) Genotyping of CYP2D6 in Parkinson's disease. Clin. Chem. Lab. Med. 38, 929-934.
-
(2000)
Clin. Chem. Lab. Med.
, vol.38
, pp. 929-934
-
-
Stefanović, M.1
Topić, E.2
Ivanisević, A.M.3
Relja, M.4
Korsić, M.5
-
61
-
-
0023950223
-
Inhibition of desipramine 2-hydroxylation by quinidine and quinine
-
Steiner E., Dumond E., Spina E., and, Dahlqvist R., (1988) Inhibition of desipramine 2-hydroxylation by quinidine and quinine. Clin. Pharmacol. Ther. 43, 577-581.
-
(1988)
Clin. Pharmacol. Ther.
, vol.43
, pp. 577-581
-
-
Steiner, E.1
Dumond, E.2
Spina, E.3
Dahlqvist, R.4
-
62
-
-
0030906094
-
Effect of cytochrome P450 2D1 inhibition on hydrocodone metabolism and its behavioral consequences in rats
-
Tomkins D. M., Otton S. V., Joharchi N., Li N.-Y., Balster R. F., Tyndale R. F., and, Sellers E. M., (1997) Effects of Cytochrome P450 2D1 inhibition on hydrocodone metabolism and its behavioral consequences in rats. J. Pharmacol. Exp. Ther. 280, 1374-1382. (Pubitemid 27166736)
-
(1997)
Journal of Pharmacology and Experimental Therapeutics
, vol.280
, Issue.3
, pp. 1374-1382
-
-
Tomkins, D.M.1
Otton, S.V.2
Joharchi, N.3
Li, N.-Y.4
Balster, R.F.5
Tyndale, R.F.6
Sellers, E.M.7
-
63
-
-
0036656069
-
The effects of antimalarial drugs on ventricular repolarization
-
Touze J.-E., Heno P., Fourcade L., Deharo J.-C., Thomas G., Bohan S., Paule P., Riviere P., Kouassi E., and, Buguet A., (2002) The effect of antimalarial drugs on ventricular repolarization. Am. J. Trop. Med. Hyg. 67, 54-60. (Pubitemid 35034320)
-
(2002)
American Journal of Tropical Medicine and Hygiene
, vol.67
, Issue.1
, pp. 54-60
-
-
Touze, J.-E.1
Heno, P.2
Fourcade, L.3
Deharo, J.-C.4
Thomas, G.5
Bohan, S.6
Paule, P.7
Riviere, P.8
Kouassi, E.9
Buguet, A.10
-
64
-
-
0027200680
-
A novel cytochrome P-450IID6 mutant gene associated with Parkinson's disease
-
Tsuneoka Y., Matsuo Y., Iwahashi K., Takeuchi H., and, Ichikawa Y., (1993) A novel cytochrome P-450IID6 mutant gene associated with Parkinson's disease. J. Biochem. 114, 263-266. (Pubitemid 23254384)
-
(1993)
Journal of Biochemistry
, vol.114
, Issue.2
, pp. 263-266
-
-
Tsuneoka, Y.1
Matsuo, Y.2
Iwahashi, K.3
Takeuchi, H.4
Ichikawa, Y.5
-
65
-
-
0032809128
-
Characterization of cytochrome P-450 2D1 activity in rat brain: High- affinity kinetics for dextromethorphan
-
Tyndale R. F., Li Y., Li N.-Y., Messina E., Miksys S., and, Sellers E. M., (1999) Characterization of cytochrome P-450 2D1 activity in rat brain: high-affinity kinetics for dextromethorphan. Drug Metab. Dispos. 27, 924-930. (Pubitemid 29347593)
-
(1999)
Drug Metabolism and Disposition
, vol.27
, Issue.8
, pp. 924-930
-
-
Tyndale, R.F.1
Li, Y.2
Li, N.-Y.3
Messina, E.4
Miksys, S.5
Sellers, E.M.6
-
66
-
-
33947715346
-
Aromatic l-amino acid decarboxylase enzyme activity in deficient patients and heterozygotes
-
DOI 10.1016/j.ymgme.2006.12.001, PII S1096719206003842
-
Verbeek M. M., Geurtz P. B. H., Willemsen M. A. A. P., and, Wevers R. A., (2007) Aromatic L-amino acid decarboxylase enzyme activity in deficient patients and heterozygotes. Mol. Genet. Metab. 90, 363-369. (Pubitemid 46505283)
-
(2007)
Molecular Genetics and Metabolism
, vol.90
, Issue.4
, pp. 363-369
-
-
Verbeek, M.M.1
Geurtz, P.B.H.2
Willemsen, M.A.A.P.3
Wevers, R.A.4
-
67
-
-
3042779902
-
Dopamine in drug abuse and addiction: Results from imaging studies and treatment implications
-
DOI 10.1038/sj.mp.4001507
-
Volkow N. D., Fowler J. S., Wang G.-J., and, Swanson J. M., (2004) Dopamine in drug abuse and addiction: results from imaging studies and treatment implications. Mol. Psychiatry 9, 557-569. (Pubitemid 38850435)
-
(2004)
Molecular Psychiatry
, vol.9
, Issue.6
, pp. 557-569
-
-
Volkow, N.D.1
Fowler, J.S.2
Wang, G.-J.3
Swanson, J.M.4
-
69
-
-
78649332050
-
Urinary dopamine in aromatic L-amino acid decarboxylase deficiency: The unsolved paradox
-
Wassenberg T., Willemsen M. A. A. P., Geurtz P. B. H., Lammens M., Verrijp K., Wilmer M., Lee W. T., Wevers R. A., and, Verbeek M. M., (2010) Urinary dopamine in aromatic L-amino acid decarboxylase deficiency: the unsolved paradox. Mol. Genet. Metab. 101, 349-356.
-
(2010)
Mol. Genet. Metab.
, vol.101
, pp. 349-356
-
-
Wassenberg, T.1
Willemsen, M.A.A.P.2
Geurtz, P.B.H.3
Lammens, M.4
Verrijp, K.5
Wilmer, M.6
Lee, W.T.7
Wevers, R.A.8
Verbeek, M.M.9
-
70
-
-
77952995720
-
Tyrosine hydroxylase deficiency: A treatable disorder of brain catecholamine biosynthesis
-
Willemsen M. A., Verbeek M. M., Kamsteeg E. J., et al. (2010) Tyrosine hydroxylase deficiency: a treatable disorder of brain catecholamine biosynthesis. Brain 133, 1810-1822.
-
(2010)
Brain
, vol.133
, pp. 1810-1822
-
-
Willemsen, M.A.1
Verbeek, M.M.2
Kamsteeg, E.J.3
-
71
-
-
0029010844
-
Cytochromes P450 of the 2D subfamily in rat brain
-
Wyss A., Gustafsson J.-Å., and, Warner M., (1995) Cytochromes P450 of the 2D subfamily in rat brain. Mol. Pharmacol. 47, 1148-1155.
-
(1995)
Mol. Pharmacol.
, vol.47
, pp. 1148-1155
-
-
Wyss, A.1
Gustafsson, J.-Å.2
Warner, M.3
-
72
-
-
0037342251
-
Regeneration of serotonin from 5-methoxytryptamine by polymorphic human CYP2D6
-
DOI 10.1097/00008571-200303000-00007
-
Yu A.-M., Idle J. R., Byrd L. G., Krausz K. W., Küpfer A., and, Gonzalez F. J., (2003) Regeneration of serotonin from 5-methoxytryptamine by polymorphic human CYP2D6. Pharmacogenetics 13, 173-181. (Pubitemid 36324247)
-
(2003)
Pharmacogenetics
, vol.13
, Issue.3
, pp. 173-181
-
-
Yu, A.-M.1
Idle, J.R.2
Byrd, L.G.3
Krausz, K.W.4
Kupfer, A.5
Gonzalez, F.J.6
-
73
-
-
39149094615
-
Chronic nicotine treatment induces rat CYP2D in the brain but not in the liver: An investigation of induction and time course: 2006 Innovations in Neuropsychopharmacology Award
-
Yue J., Miksys S., Hoffmann E., and, Tyndale R. F., (2008) Chronic nicotine treatment induces rat CYP2D in the brain but not in the liver: an investigation of induction and time course. J. Psychiatry Neurosci. 33, 54-63. (Pubitemid 351252497)
-
(2008)
Journal of Psychiatry and Neuroscience
, vol.33
, Issue.1
, pp. 54-63
-
-
Yue, J.1
Miksys, S.2
Hoffmann, E.3
Tyndale, R.F.4
-
74
-
-
0742286803
-
Cytochrome P450 2D6: Overview and update on pharmacology, genetics, biochemistry
-
DOI 10.1007/s00210-003-0832-2
-
Zanger U. M., Raimundo S., and, Eichelbaum M., (2004) Cytochrome P450 2D6: overview and update on pharmacology, genetics, biochemistry. Naunyn Schmiedebergs Arch. Pharmacol. 369, 23-37. (Pubitemid 38161221)
-
(2004)
Naunyn-Schmiedeberg's Archives of Pharmacology
, vol.369
, Issue.1
, pp. 23-37
-
-
Zanger, U.M.1
Raimundo, S.2
Eichelbaum, M.3
-
75
-
-
0028214315
-
Regulation of aromatic L-amino acid decarboxylase in rat striatal synaptosomes: Effects of dopamine receptor agonists and antagonists
-
Zhu M.-Y., Juorio A. V., Paterson I. A., and, Boulton A. A., (1994) Regulation of aromatic L-amino acid decarboxylase in rat striatal synaptosomes: effect of dopamine receptor agonist and antagonist. Br. J. Pharamcol. 112, 23-30. (Pubitemid 24151698)
-
(1994)
British Journal of Pharmacology
, vol.112
, Issue.1
, pp. 23-30
-
-
Zhu, M.-Y.1
Juorio, A.V.2
Paterson, I.A.3
Boulton, A.A.4
|