메뉴 건너뛰기




Volumn 9, Issue , 2012, Pages

Enhanced CD8 T-cell anti-viral function and clinical disease in B7-H1-deficient mice requires CD4 T cells during encephalomyelitis

Author keywords

Axonal damage; Central nervous system; Encephalomyelitis; Gliatropic coronavirus; Inflammation

Indexed keywords

GAMMA INTERFERON; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 10; INTERLEUKIN 21; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MESSENGER RNA; PROGRAMMED DEATH 1 LIGAND 1;

EID: 84870913790     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/1742-2094-9-269     Document Type: Article
Times cited : (20)

References (67)
  • 1
    • 33746215291 scopus 로고    scopus 로고
    • Cutting edge: cognate CD4 help promotes recruitment of antigen-specific CD8 T cells around dendritic cells
    • Beuneu H, Garcia Z, Bousso P. Cutting edge: cognate CD4 help promotes recruitment of antigen-specific CD8 T cells around dendritic cells. J Immunol 2006, 177:1406-1410.
    • (2006) J Immunol , vol.177 , pp. 1406-1410
    • Beuneu, H.1    Garcia, Z.2    Bousso, P.3
  • 2
    • 33645866471 scopus 로고    scopus 로고
    • Chemokines enhance immunity by guiding naive CD8+ T cells to sites of CD4+ T cell-dendritic cell interaction
    • 10.1038/nature04651, 16612374
    • Castellino F, Huang AY, Altan-Bonnet G, Stoll S, Scheinecker C, Germain RN. Chemokines enhance immunity by guiding naive CD8+ T cells to sites of CD4+ T cell-dendritic cell interaction. Nature 2006, 440:890-895. 10.1038/nature04651, 16612374.
    • (2006) Nature , vol.440 , pp. 890-895
    • Castellino, F.1    Huang, A.Y.2    Altan-Bonnet, G.3    Stoll, S.4    Scheinecker, C.5    Germain, R.N.6
  • 3
    • 73949138471 scopus 로고    scopus 로고
    • Early CD4(+) T cell help prevents partial CD8(+) T cell exhaustion and promotes maintenance of Herpes Simplex Virus 1 latency
    • 10.4049/jimmunol.0902373, 3298035, 19949087
    • Frank GM, Lepisto AJ, Freeman ML, Sheridan BS, Cherpes TL, Hendricks RL. Early CD4(+) T cell help prevents partial CD8(+) T cell exhaustion and promotes maintenance of Herpes Simplex Virus 1 latency. J Immunol 2010, 184:277-286. 10.4049/jimmunol.0902373, 3298035, 19949087.
    • (2010) J Immunol , vol.184 , pp. 277-286
    • Frank, G.M.1    Lepisto, A.J.2    Freeman, M.L.3    Sheridan, B.S.4    Cherpes, T.L.5    Hendricks, R.L.6
  • 4
    • 18844476793 scopus 로고    scopus 로고
    • A central role for CD4(+) T cells and RANTES in virus-induced central nervous system inflammation and demyelination
    • 10.1128/JVI.74.3.1415-1424.2000, 111476, 10627552
    • Lane TE, Liu MT, Chen BP, Asensio VC, Samawi RM, Paoletti AD, Campbell IL, Kunkel SL, Fox HS, Buchmeier MJ. A central role for CD4(+) T cells and RANTES in virus-induced central nervous system inflammation and demyelination. J Virol 2000, 74:1415-1424. 10.1128/JVI.74.3.1415-1424.2000, 111476, 10627552.
    • (2000) J Virol , vol.74 , pp. 1415-1424
    • Lane, T.E.1    Liu, M.T.2    Chen, B.P.3    Asensio, V.C.4    Samawi, R.M.5    Paoletti, A.D.6    Campbell, I.L.7    Kunkel, S.L.8    Fox, H.S.9    Buchmeier, M.J.10
  • 5
    • 70849099812 scopus 로고    scopus 로고
    • CD8(+) T lymphocyte mobilization to virus-infected tissue requires CD4(+) T-cell help
    • 10.1038/nature08511, 2789415, 19898495
    • Nakanishi Y, Lu B, Gerard C, Iwasaki A. CD8(+) T lymphocyte mobilization to virus-infected tissue requires CD4(+) T-cell help. Nature 2009, 462:510-513. 10.1038/nature08511, 2789415, 19898495.
    • (2009) Nature , vol.462 , pp. 510-513
    • Nakanishi, Y.1    Lu, B.2    Gerard, C.3    Iwasaki, A.4
  • 6
    • 40049101044 scopus 로고    scopus 로고
    • CD4 T cells are required for CD8 T cell survival during both primary and memory recall responses
    • Novy P, Quigley M, Huang X, Yang Y. CD4 T cells are required for CD8 T cell survival during both primary and memory recall responses. J Immunol 2007, 179:8243-8251.
    • (2007) J Immunol , vol.179 , pp. 8243-8251
    • Novy, P.1    Quigley, M.2    Huang, X.3    Yang, Y.4
  • 7
    • 79251535587 scopus 로고    scopus 로고
    • CD4+ T cells modulate expansion and survival but not functional properties of effector and memory CD8+ T cells induced by malaria sporozoites
    • 10.1371/journal.pone.0015948, 3014941, 21245909
    • Overstreet MG, Chen YC, Cockburn IA, Tse SW, Zavala F. CD4+ T cells modulate expansion and survival but not functional properties of effector and memory CD8+ T cells induced by malaria sporozoites. PLoS One 2011, 6:e15948. 10.1371/journal.pone.0015948, 3014941, 21245909.
    • (2011) PLoS One , vol.6
    • Overstreet, M.G.1    Chen, Y.C.2    Cockburn, I.A.3    Tse, S.W.4    Zavala, F.5
  • 8
    • 84857826936 scopus 로고    scopus 로고
    • CD4 T cells promote CD8 T cell immunity at the priming and effector site during viral encephalitis
    • 10.1128/JVI.06797-11, 3302259, 22205741
    • Phares TW, Stohlman SA, Hwang M, Min B, Hinton DR, Bergmann CC. CD4 T cells promote CD8 T cell immunity at the priming and effector site during viral encephalitis. J Virol 2012, 86:2416-2427. 10.1128/JVI.06797-11, 3302259, 22205741.
    • (2012) J Virol , vol.86 , pp. 2416-2427
    • Phares, T.W.1    Stohlman, S.A.2    Hwang, M.3    Min, B.4    Hinton, D.R.5    Bergmann, C.C.6
  • 9
    • 0034123842 scopus 로고    scopus 로고
    • The role of CD4(+) T helper cells in the cytotoxic T lymphocyte response to HIV-1
    • 10.1016/S0952-7915(00)00103-5, 10899028
    • Altfeld M, Rosenberg ES. The role of CD4(+) T helper cells in the cytotoxic T lymphocyte response to HIV-1. Curr Opin Immunol 2000, 12:375-380. 10.1016/S0952-7915(00)00103-5, 10899028.
    • (2000) Curr Opin Immunol , vol.12 , pp. 375-380
    • Altfeld, M.1    Rosenberg, E.S.2
  • 10
    • 0027971622 scopus 로고
    • CD4+ T cells are required to sustain CD8+ cytotoxic T-cell responses during chronic viral infection
    • 237269, 7966595
    • Matloubian M, Concepcion RJ, Ahmed R. CD4+ T cells are required to sustain CD8+ cytotoxic T-cell responses during chronic viral infection. J Virol 1994, 68:8056-8063. 237269, 7966595.
    • (1994) J Virol , vol.68 , pp. 8056-8063
    • Matloubian, M.1    Concepcion, R.J.2    Ahmed, R.3
  • 11
    • 0032416085 scopus 로고    scopus 로고
    • Viral immune evasion due to persistence of activated T cells without effector function
    • 10.1084/jem.188.12.2205, 2212420, 9858507
    • Zajac AJ, Blattman JN, Murali-Krishna K, Sourdive DJ, Suresh M, Altman JD, Ahmed R. Viral immune evasion due to persistence of activated T cells without effector function. J Exp Med 1998, 188:2205-2213. 10.1084/jem.188.12.2205, 2212420, 9858507.
    • (1998) J Exp Med , vol.188 , pp. 2205-2213
    • Zajac, A.J.1    Blattman, J.N.2    Murali-Krishna, K.3    Sourdive, D.J.4    Suresh, M.5    Altman, J.D.6    Ahmed, R.7
  • 13
    • 35648968689 scopus 로고    scopus 로고
    • PD-1 upregulation is associated with HBV-specific T cell dysfunction in chronic hepatitis B patients
    • 10.1016/j.molimm.2007.07.038, 17868872
    • Peng G, Li S, Wu W, Tan X, Chen Y, Chen Z. PD-1 upregulation is associated with HBV-specific T cell dysfunction in chronic hepatitis B patients. Mol Immunol 2008, 45:963-970. 10.1016/j.molimm.2007.07.038, 17868872.
    • (2008) Mol Immunol , vol.45 , pp. 963-970
    • Peng, G.1    Li, S.2    Wu, W.3    Tan, X.4    Chen, Y.5    Chen, Z.6
  • 14
    • 33947421722 scopus 로고    scopus 로고
    • Dysfunction and functional restoration of HCV-specific CD8 responses in chronic hepatitis C virus infection
    • 10.1002/hep.21541, 17326153
    • Penna A, Pilli M, Zerbini A, Orlandini A, Mezzadri S, Sacchelli L, Missale G, Ferrari C. Dysfunction and functional restoration of HCV-specific CD8 responses in chronic hepatitis C virus infection. Hepatology 2007, 45:588-601. 10.1002/hep.21541, 17326153.
    • (2007) Hepatology , vol.45 , pp. 588-601
    • Penna, A.1    Pilli, M.2    Zerbini, A.3    Orlandini, A.4    Mezzadri, S.5    Sacchelli, L.6    Missale, G.7    Ferrari, C.8
  • 15
    • 78149484173 scopus 로고    scopus 로고
    • Enhanced antiviral T cell function in the absence of B7-H1 is insufficient to prevent persistence but exacerbates axonal bystander damage during viral encephalomyelitis
    • 10.4049/jimmunol.1001984, 3159959, 20876353
    • Phares TW, Stohlman SA, Hinton DR, Atkinson R, Bergmann CC. Enhanced antiviral T cell function in the absence of B7-H1 is insufficient to prevent persistence but exacerbates axonal bystander damage during viral encephalomyelitis. J Immunol 2010, 185:5607-5618. 10.4049/jimmunol.1001984, 3159959, 20876353.
    • (2010) J Immunol , vol.185 , pp. 5607-5618
    • Phares, T.W.1    Stohlman, S.A.2    Hinton, D.R.3    Atkinson, R.4    Bergmann, C.C.5
  • 16
    • 57349091154 scopus 로고    scopus 로고
    • Memory CD4+ T-cell-mediated protection from lethal coronavirus encephalomyelitis
    • 10.1128/JVI.01267-08, 2593339, 18842712
    • Savarin C, Bergmann CC, Hinton DR, Ransohoff RM, Stohlman SA. Memory CD4+ T-cell-mediated protection from lethal coronavirus encephalomyelitis. J Virol 2008, 82:12432-12440. 10.1128/JVI.01267-08, 2593339, 18842712.
    • (2008) J Virol , vol.82 , pp. 12432-12440
    • Savarin, C.1    Bergmann, C.C.2    Hinton, D.R.3    Ransohoff, R.M.4    Stohlman, S.A.5
  • 17
    • 39749155148 scopus 로고    scopus 로고
    • CD4 T cells contribute to virus control and pathology following central nervous system infection with neurotropic mouse hepatitis virus
    • 10.1128/JVI.01762-07, 2258904, 18094171
    • Stohlman SA, Hinton DR, Parra B, Atkinson R, Bergmann CC. CD4 T cells contribute to virus control and pathology following central nervous system infection with neurotropic mouse hepatitis virus. J Virol 2008, 82:2130-2139. 10.1128/JVI.01762-07, 2258904, 18094171.
    • (2008) J Virol , vol.82 , pp. 2130-2139
    • Stohlman, S.A.1    Hinton, D.R.2    Parra, B.3    Atkinson, R.4    Bergmann, C.C.5
  • 18
    • 0024347818 scopus 로고
    • T-cell-mediated clearance of mouse hepatitis virus strain JHM from the central nervous system
    • 250860, 2542613
    • Sussman MA, Shubin RA, Kyuwa S, Stohlman SA. T-cell-mediated clearance of mouse hepatitis virus strain JHM from the central nervous system. J Virol 1989, 63:3051-3056. 250860, 2542613.
    • (1989) J Virol , vol.63 , pp. 3051-3056
    • Sussman, M.A.1    Shubin, R.A.2    Kyuwa, S.3    Stohlman, S.A.4
  • 19
    • 0025047026 scopus 로고
    • Effective clearance of mouse hepatitis virus from the central nervous system requires both CD4+ and CD8+ T cells
    • 247935, 2166833
    • Williamson JS, Stohlman SA. Effective clearance of mouse hepatitis virus from the central nervous system requires both CD4+ and CD8+ T cells. J Virol 1990, 64:4589-4592. 247935, 2166833.
    • (1990) J Virol , vol.64 , pp. 4589-4592
    • Williamson, J.S.1    Stohlman, S.A.2
  • 20
    • 0033568030 scopus 로고    scopus 로고
    • Inverted immunodominance and impaired cytolytic function of CD8+ T cells during viral persistence in the central nervous system
    • Bergmann CC, Altman JD, Hinton D, Stohlman SA. Inverted immunodominance and impaired cytolytic function of CD8+ T cells during viral persistence in the central nervous system. J Immunol 1999, 163:3379-3387.
    • (1999) J Immunol , vol.163 , pp. 3379-3387
    • Bergmann, C.C.1    Altman, J.D.2    Hinton, D.3    Stohlman, S.A.4
  • 21
    • 31544476315 scopus 로고    scopus 로고
    • Coronavirus infection of the central nervous system: host-virus stand-off
    • 10.1038/nrmicro1343, 16415928
    • Bergmann CC, Lane TE, Stohlman SA. Coronavirus infection of the central nervous system: host-virus stand-off. Nat Rev Microbiol 2006, 4:121-132. 10.1038/nrmicro1343, 16415928.
    • (2006) Nat Rev Microbiol , vol.4 , pp. 121-132
    • Bergmann, C.C.1    Lane, T.E.2    Stohlman, S.A.3
  • 22
    • 66949159493 scopus 로고    scopus 로고
    • Target-dependent B7-H1 regulation contributes to clearance of central nervous system infection and dampens morbidity
    • 10.4049/jimmunol.0803557, 2909606, 19380790
    • Phares TW, Ramakrishna C, Parra GI, Epstein A, Chen L, Atkinson R, Stohlman SA, Bergmann CC. Target-dependent B7-H1 regulation contributes to clearance of central nervous system infection and dampens morbidity. J Immunol 2009, 182:5430-5438. 10.4049/jimmunol.0803557, 2909606, 19380790.
    • (2009) J Immunol , vol.182 , pp. 5430-5438
    • Phares, T.W.1    Ramakrishna, C.2    Parra, G.I.3    Epstein, A.4    Chen, L.5    Atkinson, R.6    Stohlman, S.A.7    Bergmann, C.C.8
  • 23
    • 38949145795 scopus 로고    scopus 로고
    • Induction of class I antigen processing components in oligodendroglia and microglia during viral encephalomyelitis
    • 10.1002/glia.20625, 18205173
    • Malone KE, Stohlman SA, Ramakrishna C, Macklin W, Bergmann CC. Induction of class I antigen processing components in oligodendroglia and microglia during viral encephalomyelitis. Glia 2008, 56:426-435. 10.1002/glia.20625, 18205173.
    • (2008) Glia , vol.56 , pp. 426-435
    • Malone, K.E.1    Stohlman, S.A.2    Ramakrishna, C.3    Macklin, W.4    Bergmann, C.C.5
  • 24
    • 33745714786 scopus 로고    scopus 로고
    • Pathogenic role for virus-specific CD4 T cells in mice with coronavirus-induced acute encephalitis
    • 10.2353/ajpath.2006.051308, 1698761, 16816374
    • Anghelina D, Pewe L, Perlman S. Pathogenic role for virus-specific CD4 T cells in mice with coronavirus-induced acute encephalitis. Am J Pathol 2006, 169:209-222. 10.2353/ajpath.2006.051308, 1698761, 16816374.
    • (2006) Am J Pathol , vol.169 , pp. 209-222
    • Anghelina, D.1    Pewe, L.2    Perlman, S.3
  • 25
    • 1642306942 scopus 로고    scopus 로고
    • B7-H1 determines accumulation and deletion of intrahepatic CD8(+) T lymphocytes
    • 10.1016/S1074-7613(04)00050-0, 15030776
    • Dong H, Zhu G, Tamada K, Flies DB, van Deursen JM, Chen L. B7-H1 determines accumulation and deletion of intrahepatic CD8(+) T lymphocytes. Immunity 2004, 20:327-336. 10.1016/S1074-7613(04)00050-0, 15030776.
    • (2004) Immunity , vol.20 , pp. 327-336
    • Dong, H.1    Zhu, G.2    Tamada, K.3    Flies, D.B.4    van Deursen, J.M.5    Chen, L.6
  • 26
    • 0022446017 scopus 로고
    • Pathogenicity of antigenic variants of murine coronavirus JHM selected with monoclonal antibodies
    • 252994, 3701929
    • Fleming JO, Trousdale MD, El-Zaatari FA, Stohlman SA, Weiner LP. Pathogenicity of antigenic variants of murine coronavirus JHM selected with monoclonal antibodies. J Virol 1986, 58:869-875. 252994, 3701929.
    • (1986) J Virol , vol.58 , pp. 869-875
    • Fleming, J.O.1    Trousdale, M.D.2    El-Zaatari, F.A.3    Stohlman, S.A.4    Weiner, L.P.5
  • 28
    • 79952374885 scopus 로고    scopus 로고
    • Factors supporting intrathecal humoral responses following viral encephalomyelitis
    • 10.1128/JVI.02260-10, 3067923, 21191015
    • Phares TW, Marques CP, Stohlman SA, Hinton DR, Bergmann CC. Factors supporting intrathecal humoral responses following viral encephalomyelitis. J Virol 2011, 85:2589-2598. 10.1128/JVI.02260-10, 3067923, 21191015.
    • (2011) J Virol , vol.85 , pp. 2589-2598
    • Phares, T.W.1    Marques, C.P.2    Stohlman, S.A.3    Hinton, D.R.4    Bergmann, C.C.5
  • 29
    • 79953222926 scopus 로고    scopus 로고
    • Highly activated cytotoxic CD8 T cells express protective IL-10 at the peak of coronavirus-induced encephalitis
    • 10.4049/jimmunol.1003292, 3063297, 21317392
    • Trandem K, Zhao J, Fleming E, Perlman S. Highly activated cytotoxic CD8 T cells express protective IL-10 at the peak of coronavirus-induced encephalitis. J Immunol 2011, 186:3642-3652. 10.4049/jimmunol.1003292, 3063297, 21317392.
    • (2011) J Immunol , vol.186 , pp. 3642-3652
    • Trandem, K.1    Zhao, J.2    Fleming, E.3    Perlman, S.4
  • 30
    • 84865321249 scopus 로고    scopus 로고
    • Oligodendroglia are limited in type I interferon induction and responsiveness in vivo
    • 10.1002/glia.22375, 22736486
    • Kapil P, Butchi NB, Stohlman SA, Bergmann CC. Oligodendroglia are limited in type I interferon induction and responsiveness in vivo. Glia 2012, 60:1555-1566. 10.1002/glia.22375, 22736486.
    • (2012) Glia , vol.60 , pp. 1555-1566
    • Kapil, P.1    Butchi, N.B.2    Stohlman, S.A.3    Bergmann, C.C.4
  • 32
    • 67649217469 scopus 로고    scopus 로고
    • IL-21 is required to control chronic viral infection
    • 10.1126/science.1174182, 2830017, 19423777
    • Elsaesser H, Sauer K, Brooks DG. IL-21 is required to control chronic viral infection. Science 2009, 324:1569-1572. 10.1126/science.1174182, 2830017, 19423777.
    • (2009) Science , vol.324 , pp. 1569-1572
    • Elsaesser, H.1    Sauer, K.2    Brooks, D.G.3
  • 33
    • 67649234772 scopus 로고    scopus 로고
    • IL-21R on T cells is critical for sustained functionality and control of chronic viral infection
    • 10.1126/science.1172815, 19478140
    • Frohlich A, Kisielow J, Schmitz I, Freigang S, Shamshiev AT, Weber J, Marsland BJ, Oxenius A, Kopf M. IL-21R on T cells is critical for sustained functionality and control of chronic viral infection. Science 2009, 324:1576-1580. 10.1126/science.1172815, 19478140.
    • (2009) Science , vol.324 , pp. 1576-1580
    • Frohlich, A.1    Kisielow, J.2    Schmitz, I.3    Freigang, S.4    Shamshiev, A.T.5    Weber, J.6    Marsland, B.J.7    Oxenius, A.8    Kopf, M.9
  • 34
    • 79952753925 scopus 로고    scopus 로고
    • Intrinsic IL-21 signaling is critical for CD8 T cell survival and memory formation in response to vaccinia viral infection
    • 10.4049/jimmunol.1003009, 3059504, 21257966
    • Novy P, Huang X, Leonard WJ, Yang Y. Intrinsic IL-21 signaling is critical for CD8 T cell survival and memory formation in response to vaccinia viral infection. J Immunol 2011, 186:2729-2738. 10.4049/jimmunol.1003009, 3059504, 21257966.
    • (2011) J Immunol , vol.186 , pp. 2729-2738
    • Novy, P.1    Huang, X.2    Leonard, W.J.3    Yang, Y.4
  • 35
    • 67649203681 scopus 로고    scopus 로고
    • A vital role for interleukin-21 in the control of a chronic viral infection
    • 10.1126/science.1175194, 2736049, 19443735
    • Yi JS, Du M, Zajac AJ. A vital role for interleukin-21 in the control of a chronic viral infection. Science 2009, 324:1572-1576. 10.1126/science.1175194, 2736049, 19443735.
    • (2009) Science , vol.324 , pp. 1572-1576
    • Yi, J.S.1    Du, M.2    Zajac, A.J.3
  • 36
    • 34547643598 scopus 로고    scopus 로고
    • Distinct regulation of MHC molecule expression on astrocytes and microglia during viral encephalomyelitis
    • 10.1002/glia.20538, 17600339
    • Hamo L, Stohlman SA, Otto-Duessel M, Bergmann CC. Distinct regulation of MHC molecule expression on astrocytes and microglia during viral encephalomyelitis. Glia 2007, 55:1169-1177. 10.1002/glia.20538, 17600339.
    • (2007) Glia , vol.55 , pp. 1169-1177
    • Hamo, L.1    Stohlman, S.A.2    Otto-Duessel, M.3    Bergmann, C.C.4
  • 37
    • 33144463727 scopus 로고    scopus 로고
    • Preferential infection of mature dendritic cells by mouse hepatitis virus strain JHM
    • 10.1128/JVI.80.5.2506-2514.2006, 1395395, 16474157
    • Zhou H, Perlman S. Preferential infection of mature dendritic cells by mouse hepatitis virus strain JHM. J Virol 2006, 80:2506-2514. 10.1128/JVI.80.5.2506-2514.2006, 1395395, 16474157.
    • (2006) J Virol , vol.80 , pp. 2506-2514
    • Zhou, H.1    Perlman, S.2
  • 39
    • 33646506651 scopus 로고    scopus 로고
    • Deleterious role of IFNgamma in a toxic model of central nervous system demyelination
    • 10.2353/ajpath.2006.050799, 1606575, 16651614
    • Mana P, Linares D, Fordham S, Staykova M, Willenborg D. Deleterious role of IFNgamma in a toxic model of central nervous system demyelination. Am J Pathol 2006, 168:1464-1473. 10.2353/ajpath.2006.050799, 1606575, 16651614.
    • (2006) Am J Pathol , vol.168 , pp. 1464-1473
    • Mana, P.1    Linares, D.2    Fordham, S.3    Staykova, M.4    Willenborg, D.5
  • 40
    • 0031063399 scopus 로고    scopus 로고
    • The effects of interferon-gamma on the central nervous system
    • 10.1007/BF02740619, 9170099
    • Popko B, Corbin JG, Baerwald KD, Dupree J, Garcia AM. The effects of interferon-gamma on the central nervous system. Mol Neurobiol 1997, 14:19-35. 10.1007/BF02740619, 9170099.
    • (1997) Mol Neurobiol , vol.14 , pp. 19-35
    • Popko, B.1    Corbin, J.G.2    Baerwald, K.D.3    Dupree, J.4    Garcia, A.M.5
  • 41
    • 49649116172 scopus 로고    scopus 로고
    • CD8+ T lymphocytes control murine cytomegalovirus replication in the central nervous system of newborn animals
    • Bantug GR, Cekinovic D, Bradford R, Koontz T, Jonjic S, Britt WJ. CD8+ T lymphocytes control murine cytomegalovirus replication in the central nervous system of newborn animals. J Immunol 2008, 181:2111-2123.
    • (2008) J Immunol , vol.181 , pp. 2111-2123
    • Bantug, G.R.1    Cekinovic, D.2    Bradford, R.3    Koontz, T.4    Jonjic, S.5    Britt, W.J.6
  • 42
    • 0026554713 scopus 로고
    • Anti-CD8 impairs clearance of herpes simplex virus from the nervous system: implications for the fate of virally infected neurons
    • 10.1084/jem.175.5.1337, 2119218, 1314887
    • Simmons A, Tscharke DC. Anti-CD8 impairs clearance of herpes simplex virus from the nervous system: implications for the fate of virally infected neurons. J Exp Med 1992, 175:1337-1344. 10.1084/jem.175.5.1337, 2119218, 1314887.
    • (1992) J Exp Med , vol.175 , pp. 1337-1344
    • Simmons, A.1    Tscharke, D.C.2
  • 43
    • 0034094220 scopus 로고    scopus 로고
    • The role of CD8(+) T cells and major histocompatibility complex class I expression in the central nervous system of mice infected with neurovirulent Sindbis virus
    • 10.1128/JVI.74.13.6117-6125.2000, 112110, 10846095
    • Kimura T, Griffin DE. The role of CD8(+) T cells and major histocompatibility complex class I expression in the central nervous system of mice infected with neurovirulent Sindbis virus. J Virol 2000, 74:6117-6125. 10.1128/JVI.74.13.6117-6125.2000, 112110, 10846095.
    • (2000) J Virol , vol.74 , pp. 6117-6125
    • Kimura, T.1    Griffin, D.E.2
  • 44
    • 3242677841 scopus 로고    scopus 로고
    • Role of CD8+ T cells in control of West Nile virus infection
    • 10.1128/JVI.78.15.8312-8321.2004, 446114, 15254203
    • Shrestha B, Diamond MS. Role of CD8+ T cells in control of West Nile virus infection. J Virol 2004, 78:8312-8321. 10.1128/JVI.78.15.8312-8321.2004, 446114, 15254203.
    • (2004) J Virol , vol.78 , pp. 8312-8321
    • Shrestha, B.1    Diamond, M.S.2
  • 46
    • 33749324118 scopus 로고    scopus 로고
    • Reinvigorating exhausted HIV-specific T cells via PD-1-PD-1 ligand blockade
    • 10.1084/jem.20061800, 2118103, 17000870
    • Freeman GJ, Wherry EJ, Ahmed R, Sharpe AH. Reinvigorating exhausted HIV-specific T cells via PD-1-PD-1 ligand blockade. J Exp Med 2006, 203:2223-2227. 10.1084/jem.20061800, 2118103, 17000870.
    • (2006) J Exp Med , vol.203 , pp. 2223-2227
    • Freeman, G.J.1    Wherry, E.J.2    Ahmed, R.3    Sharpe, A.H.4
  • 48
    • 39849088117 scopus 로고    scopus 로고
    • Restoration of HCV-specific T cell functions by PD-1/PD-L1 blockade in HCV infection: effect of viremia levels and antiviral treatment
    • 10.1016/j.jhep.2007.12.014, 18280607
    • Urbani S, Amadei B, Tola D, Pedrazzi G, Sacchelli L, Cavallo MC, Orlandini A, Missale G, Ferrari C. Restoration of HCV-specific T cell functions by PD-1/PD-L1 blockade in HCV infection: effect of viremia levels and antiviral treatment. J Hepatol 2008, 48:548-558. 10.1016/j.jhep.2007.12.014, 18280607.
    • (2008) J Hepatol , vol.48 , pp. 548-558
    • Urbani, S.1    Amadei, B.2    Tola, D.3    Pedrazzi, G.4    Sacchelli, L.5    Cavallo, M.C.6    Orlandini, A.7    Missale, G.8    Ferrari, C.9
  • 49
    • 49649111913 scopus 로고    scopus 로고
    • B7-H1 restricts neuroantigen-specific T cell responses and confines inflammatory CNS damage: implications for the lesion pathogenesis of multiple sclerosis
    • 10.1002/eji.200738071, 18421793
    • Ortler S, Leder C, Mittelbronn M, Zozulya AL, Knolle PA, Chen L, Kroner A, Wiendl H. B7-H1 restricts neuroantigen-specific T cell responses and confines inflammatory CNS damage: implications for the lesion pathogenesis of multiple sclerosis. Eur J Immunol 2008, 38:1734-1744. 10.1002/eji.200738071, 18421793.
    • (2008) Eur J Immunol , vol.38 , pp. 1734-1744
    • Ortler, S.1    Leder, C.2    Mittelbronn, M.3    Zozulya, A.L.4    Knolle, P.A.5    Chen, L.6    Kroner, A.7    Wiendl, H.8
  • 50
    • 84864321408 scopus 로고    scopus 로고
    • CD4(+) T cells rely on a cytokine gradient to control intracellular pathogens beyond sites of antigen presentation
    • 10.1016/j.immuni.2012.05.015, 22727490
    • Muller AJ, Filipe-Santos O, Eberl G, Aebischer T, Spath GF, Bousso P. CD4(+) T cells rely on a cytokine gradient to control intracellular pathogens beyond sites of antigen presentation. Immunity 2012, 37:147-157. 10.1016/j.immuni.2012.05.015, 22727490.
    • (2012) Immunity , vol.37 , pp. 147-157
    • Muller, A.J.1    Filipe-Santos, O.2    Eberl, G.3    Aebischer, T.4    Spath, G.F.5    Bousso, P.6
  • 51
    • 33846327273 scopus 로고    scopus 로고
    • Absence of perforin expression confers axonal protection despite demyelination
    • 10.1016/j.nbd.2006.10.001, 1857307, 17112732
    • Howe CL, Adelson JD, Rodriguez M. Absence of perforin expression confers axonal protection despite demyelination. Neurobiol Dis 2007, 25:354-359. 10.1016/j.nbd.2006.10.001, 1857307, 17112732.
    • (2007) Neurobiol Dis , vol.25 , pp. 354-359
    • Howe, C.L.1    Adelson, J.D.2    Rodriguez, M.3
  • 53
    • 18744390313 scopus 로고    scopus 로고
    • Viral expression of CCL2 is sufficient to induce demyelination in RAG1-/- mice infected with a neurotropic coronavirus
    • 10.1128/JVI.79.11.7113-7120.2005, 1112157, 15890951
    • Kim TS, Perlman S. Viral expression of CCL2 is sufficient to induce demyelination in RAG1-/- mice infected with a neurotropic coronavirus. J Virol 2005, 79:7113-7120. 10.1128/JVI.79.11.7113-7120.2005, 1112157, 15890951.
    • (2005) J Virol , vol.79 , pp. 7113-7120
    • Kim, T.S.1    Perlman, S.2
  • 54
    • 77951494843 scopus 로고    scopus 로고
    • Monocytes regulate T cell migration through the glia limitans during acute viral encephalitis
    • 10.1128/JVI.00051-10, 2863800, 20200240
    • Savarin C, Stohlman SA, Atkinson R, Ransohoff RM, Bergmann CC. Monocytes regulate T cell migration through the glia limitans during acute viral encephalitis. J Virol 2010, 84:4878-4888. 10.1128/JVI.00051-10, 2863800, 20200240.
    • (2010) J Virol , vol.84 , pp. 4878-4888
    • Savarin, C.1    Stohlman, S.A.2    Atkinson, R.3    Ransohoff, R.M.4    Bergmann, C.C.5
  • 55
    • 84857976072 scopus 로고    scopus 로고
    • Inflammatory monocytes damage the hippocampus during acute picornavirus infection of the brain
    • 10.1186/1742-2094-9-50, 3368782, 22405261
    • Howe CL, Lafrance-Corey RG, Sundsbak RS, Lafrance SJ. Inflammatory monocytes damage the hippocampus during acute picornavirus infection of the brain. J Neuroinflammation 2012, 9:50. 10.1186/1742-2094-9-50, 3368782, 22405261.
    • (2012) J Neuroinflammation , vol.9 , pp. 50
    • Howe, C.L.1    Lafrance-Corey, R.G.2    Sundsbak, R.S.3    Lafrance, S.J.4
  • 56
    • 80052246111 scopus 로고    scopus 로고
    • Infiltrating monocytes trigger EAE progression, but do not contribute to the resident microglia pool
    • 10.1038/nn.2887, 21804537
    • Ajami B, Bennett JL, Krieger C, McNagny KM, Rossi FM. Infiltrating monocytes trigger EAE progression, but do not contribute to the resident microglia pool. Nat Neurosci 2011, 14:1142-1149. 10.1038/nn.2887, 21804537.
    • (2011) Nat Neurosci , vol.14 , pp. 1142-1149
    • Ajami, B.1    Bennett, J.L.2    Krieger, C.3    McNagny, K.M.4    Rossi, F.M.5
  • 58
    • 0029592005 scopus 로고
    • Activation of the inducible form of nitric oxide synthase in the brains of patients with multiple sclerosis
    • 10.1073/pnas.92.26.12041, 40292, 8618840
    • Bagasra O, Michaels FH, Zheng YM, Bobroski LE, Spitsin SV, Fu ZF, Tawadros R, Koprowski H. Activation of the inducible form of nitric oxide synthase in the brains of patients with multiple sclerosis. Proc Natl Acad Sci U S A 1995, 92:12041-12045. 10.1073/pnas.92.26.12041, 40292, 8618840.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 12041-12045
    • Bagasra, O.1    Michaels, F.H.2    Zheng, Y.M.3    Bobroski, L.E.4    Spitsin, S.V.5    Fu, Z.F.6    Tawadros, R.7    Koprowski, H.8
  • 59
    • 0027973242 scopus 로고
    • Induction of nitric oxide synthase in demyelinating regions of multiple sclerosis brains
    • 10.1002/ana.410360515, 7526776
    • Bo L, Dawson TM, Wesselingh S, Mork S, Choi S, Kong PA, Hanley D, Trapp BD. Induction of nitric oxide synthase in demyelinating regions of multiple sclerosis brains. Ann Neurol 1994, 36:778-786. 10.1002/ana.410360515, 7526776.
    • (1994) Ann Neurol , vol.36 , pp. 778-786
    • Bo, L.1    Dawson, T.M.2    Wesselingh, S.3    Mork, S.4    Choi, S.5    Kong, P.A.6    Hanley, D.7    Trapp, B.D.8
  • 60
    • 0028868821 scopus 로고
    • Expression of the inducible isoform of nitric oxide synthase in the central nervous system of mice correlates with the severity of actively induced experimental allergic encephalomyelitis
    • 10.1016/0165-5728(95)00114-H, 7499486
    • Okuda Y, Nakatsuji Y, Fujimura H, Esumi H, Ogura T, Yanagihara T, Sakoda S. Expression of the inducible isoform of nitric oxide synthase in the central nervous system of mice correlates with the severity of actively induced experimental allergic encephalomyelitis. J Neuroimmunol 1995, 62:103-112. 10.1016/0165-5728(95)00114-H, 7499486.
    • (1995) J Neuroimmunol , vol.62 , pp. 103-112
    • Okuda, Y.1    Nakatsuji, Y.2    Fujimura, H.3    Esumi, H.4    Ogura, T.5    Yanagihara, T.6    Sakoda, S.7
  • 61
    • 0029052310 scopus 로고
    • Local nitric oxide production in viral and autoimmune diseases of the central nervous system
    • 10.1073/pnas.92.12.5312, 41684, 7539914
    • Hooper DC, Ohnishi ST, Kean R, Numagami Y, Dietzschold B, Koprowski H. Local nitric oxide production in viral and autoimmune diseases of the central nervous system. Proc Natl Acad Sci U S A 1995, 92:5312-5316. 10.1073/pnas.92.12.5312, 41684, 7539914.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 5312-5316
    • Hooper, D.C.1    Ohnishi, S.T.2    Kean, R.3    Numagami, Y.4    Dietzschold, B.5    Koprowski, H.6
  • 62
    • 0030560858 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase gene expression and enzyme activity correlate with disease activity in murine experimental autoimmune encephalomyelitis
    • 10.1016/S0165-5728(96)00147-6, 8982114
    • Cross AH, Keeling RM, Goorha S, San M, Rodi C, Wyatt PS, Manning PT, Misko TP. Inducible nitric oxide synthase gene expression and enzyme activity correlate with disease activity in murine experimental autoimmune encephalomyelitis. J Neuroimmunol 1996, 71:145-153. 10.1016/S0165-5728(96)00147-6, 8982114.
    • (1996) J Neuroimmunol , vol.71 , pp. 145-153
    • Cross, A.H.1    Keeling, R.M.2    Goorha, S.3    San, M.4    Rodi, C.5    Wyatt, P.S.6    Manning, P.T.7    Misko, T.P.8
  • 63
    • 0025874048 scopus 로고
    • Peroxynitrite-induced membrane lipid peroxidation: the cytotoxic potential of superoxide and nitric oxide
    • 10.1016/0003-9861(91)90224-7, 1654835
    • Radi R, Beckman JS, Bush KM, Freeman BA. Peroxynitrite-induced membrane lipid peroxidation: the cytotoxic potential of superoxide and nitric oxide. Arch Biochem Biophys 1991, 288:481-487. 10.1016/0003-9861(91)90224-7, 1654835.
    • (1991) Arch Biochem Biophys , vol.288 , pp. 481-487
    • Radi, R.1    Beckman, J.S.2    Bush, K.M.3    Freeman, B.A.4
  • 64
    • 0025730414 scopus 로고
    • Peroxynitrite oxidation of sulfhydryls. The cytotoxic potential of superoxide and nitric oxide
    • Radi R, Beckman JS, Bush KM, Freeman BA. Peroxynitrite oxidation of sulfhydryls. The cytotoxic potential of superoxide and nitric oxide. J Biol Chem 1991, 266:4244-4250.
    • (1991) J Biol Chem , vol.266 , pp. 4244-4250
    • Radi, R.1    Beckman, J.S.2    Bush, K.M.3    Freeman, B.A.4
  • 65
    • 0029959717 scopus 로고    scopus 로고
    • DNA strand breakage and activation of poly-ADP ribosyltransferase: a cytotoxic pathway triggered by peroxynitrite
    • 10.1016/0891-5849(96)00170-0, 8902531
    • Szabo C. DNA strand breakage and activation of poly-ADP ribosyltransferase: a cytotoxic pathway triggered by peroxynitrite. Free Radic Biol Med 1996, 21:855-869. 10.1016/0891-5849(96)00170-0, 8902531.
    • (1996) Free Radic Biol Med , vol.21 , pp. 855-869
    • Szabo, C.1
  • 67
    • 0033854596 scopus 로고    scopus 로고
    • Coronavirus-induced demyelination occurs in the absence of inducible nitric oxide synthase
    • 10.1128/JVI.74.16.7683-7686.2000, 112293, 10906226
    • Wu GF, Pewe L, Perlman S. Coronavirus-induced demyelination occurs in the absence of inducible nitric oxide synthase. J Virol 2000, 74:7683-7686. 10.1128/JVI.74.16.7683-7686.2000, 112293, 10906226.
    • (2000) J Virol , vol.74 , pp. 7683-7686
    • Wu, G.F.1    Pewe, L.2    Perlman, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.