Search for new tools to combat Gram-negative resistant bacteria among amine derivatives of 5-arylidenehydantoin

Bioorganic and Medicinal Chemistry

Volumn 21, Issue 1, 2013, Pages 135-145

  Handzlik, Jadwiga ^a,c   Szymańska, Ewa ^a   Alibert, Sandrine ^b,c   Chevalier, Jacqueline ^b   Otrȩbska, Ewa ^a,c   Pȩkala, Elzbieta ^a   Pagès, Jean Marie ^b,c   Kieć Kononowicz, Katarzyna ^a,c  

^a JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE   (Poland)

^b Aix Marseille University   (France)

^c COST Action BM0701 ^*  (Belgium)

Author keywords

AcrAB TolC; Arylidenehydantoin; Arylideneimidazolidine 2,4 dione; Efflux pump; Enterobacter aerogenes; Multidrug resistance

Indexed keywords

5 (4 CHLOROBENZYLIDENE) 3 (OXIRAN 2 YLMETHYL)IMIDAZOLIDINE 2,4 DIONE; 5 (4 METHOXYBENZYLIDENE) 3 (2 HYDROXY 3 (4 METHYLPIPERAZIN 1 YL)PROPYL)IMIDAZOLIDINE 2,4 DIONE; 5 (4 METHOXYBENZYLIDENE) 3 (2 HYDROXY 3 (4 PIPERAZIN 1 YL)PROPYL)IMIDAZOLIDINE 2,4 DIONE; 5 (4 METHOXYBENZYLIDENE) 3 (OXIRAN 2 YLMETHYL)IMIDAZOLIDINE 2,4 DIONE; 5 ARYLIDENE 3 (OXIRAN 2 YLMETHYL)IMIDAZOLIDINE 2,4 DIONE DERIVATIVE; 5 ARYLIDENEHYDANTOIN DERIVATIVE; 5 BENZYLIDENE 3 (OXIRAN 2 YLMETHYL)IMIDAZOLIDINE 2,4 DIONE; ANTIINFECTIVE AGENT; CHLORAMPHENICOL; HYDANTOIN DERIVATIVE; NALIDIXIC ACID; QUINOLINE DERIVATIVE; SPARFLOXACIN; UNCLASSIFIED DRUG;

ALKYLATION; ANTIBACTERIAL ACTIVITY; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL STRAIN; CONTROLLED STUDY; DRUG SCREENING; DRUG SYNTHESIS; ENTEROBACTER AEROGENES; GENE OVEREXPRESSION; ION TRANSPORT; KNOEVENAGEL CONDENSATION; MICROWAVE RADIATION; MINIMUM INHIBITORY CONCENTRATION; MITSUNOBU REACTION; MOLECULAR MODEL; NONHUMAN; STRUCTURE ACTIVITY RELATION;

AMINES; ANTI-BACTERIAL AGENTS; DRUG RESISTANCE, MULTIPLE, BACTERIAL; ENTEROBACTER AEROGENES; ENTEROBACTERIACEAE INFECTIONS; HUMANS; HYDANTOINS; MODELS, MOLECULAR;

ENTEROBACTER AEROGENES; NEGIBACTERIA;

EID: 84870875143     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2012.10.053     Document Type: Article

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