Macrolactonolides: A novel class of anti-inflammatory compounds

Bioorganic and Medicinal Chemistry

Volumn 21, Issue 1, 2013, Pages 321-332

  Tomašković, Linda ^a   Komac, Marijana ^a   Makaruha Stegić, Oresta ^a,b   Munić, Vesna ^a   Ralić, Jovica ^a   Stanić, Barbara ^a,d   Banjanac, Mihailo ^a   Marković, Stribor ^a,c   Hrvačić, Boška ^a   Čipčić Paljetak, Hana ^a,e   Padovan, Jasna ^a   Glojnarić, Ines ^a   Eraković Haber, Vesna ^a   Mesić, Milan ^a   Merćep, Mladen ^a,d  

^a GLAXOSMITHKLINE   (United Kingdom)

^b Xellia Pharmaceuticals   (Croatia)

^c UNIVERSITY OF ZAGREB   (Croatia)

^d Children Hospital Srebrnjak   (Croatia)

^e UNIVERSITY OF ZAGREB   (Croatia)

Author keywords

Anti inflammatory activity; Glucocorticoid; Macrolide

Indexed keywords

ANTIINFLAMMATORY AGENT; AZITHROMYCIN; BECLOMETASONE DIPROPIONATE; CORTICOSTERONE; DESOXIMETASONE; DEXAMETHASONE; FLUMETASONE; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HYDROCORTISONE; INTERLEUKIN 10; INTERLEUKIN 12P70; INTERLEUKIN 13; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 3; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; INTERLEUKIN 8; ISOFLUPREDONE; MACROLACTONOLIDE DERIVATIVE; MACROLIDE; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; METHYLPREDNISOLONE; MONOCYTE CHEMOTACTIC PROTEIN 1; PARAMETHASONE; PREDNISOLONE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBACTERIAL ACTIVITY; ANTIINFLAMMATORY ACTIVITY; AREA UNDER THE CURVE; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG DESIGN; DRUG HALF LIFE; DRUG RECEPTOR BINDING; DRUG RETENTION; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; HYDROGENATION; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; LIGAND BINDING; LUNG LAVAGE; MALE; MAXIMUM PLASMA CONCENTRATION; MICHAEL ADDITION; MINIMUM INHIBITORY CONCENTRATION; MOUSE; NONHUMAN; RAT; STRUCTURE ACTIVITY RELATION; THIN LAYER CHROMATOGRAPHY; TIME TO MAXIMUM PLASMA CONCENTRATION;

ANIMALS; ANTI-INFLAMMATORY AGENTS; ASTHMA; CARBOXYLIC ACIDS; CELL LINE; DRUG DESIGN; GLUCOCORTICOIDS; MACROLIDES; MALE; MICE; MICE, INBRED BALB C; RATS; RATS, INBRED BN; STEROIDS;

RATTUS;

EID: 84870873252     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2012.10.036     Document Type: Article

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