-
1
-
-
0001199533
-
Chemical aspects of selective toxicity
-
Albert, A., Chemical aspects of selective toxicity. Nature, 182, 421-423 (1958).
-
(1958)
Nature
, vol.182
, pp. 421-423
-
-
Albert, A.1
-
2
-
-
0025188612
-
In vitro hydrolysis of steroid acid ester derivatives of prednisolone in plasma of different species
-
Al-Habet, S. M. H. and Lee, H. J., In vitro hydrolysis of steroid acid ester derivatives of prednisolone in plasma of different species. J. Pharm. Sci., 79, 916-918 (1990).
-
(1990)
J. Pharm. Sci.
, vol.79
, pp. 916-918
-
-
Al-Habet, S.M.H.1
Lee, H.J.2
-
3
-
-
0000136353
-
Antiinflammatory steroids
-
Wolfe, M. E. (Ed). John Wiley & Sons, Inc.
-
Avery, M. A. and Woolfrey, J. R., Antiinflammatory steroids: Wolfe, M. E. (Ed). Medicinal Chemistry and Drug Discovery, John Wiley & Sons, Inc., pp. 281-376 (1997).
-
(1997)
Medicinal Chemistry and Drug Discovery
, pp. 281-376
-
-
Avery, M.A.1
Woolfrey, J.R.2
-
4
-
-
0022454697
-
The effects of new local anti-inflammatory steroids on leucocyte migration and prostanoid liberation in rats
-
Bird, J., Lay, J. C. and Lee, H. J., The effects of new local anti-inflammatory steroids on leucocyte migration and prostanoid liberation in rats. J. Pharm. Pharmacol., 38, 589-594 (1986a).
-
(1986)
J. Pharm. Pharmacol.
, vol.38
, pp. 589-594
-
-
Bird, J.1
Lay, J.C.2
Lee, H.J.3
-
5
-
-
0023027129
-
Topical anti-inflammatory activity of esters of steroid-21-oic acids
-
Bird, J., Kim, H. P. and Lee, H. J., Topical anti-inflammatory activity of esters of steroid-21-oic acids. Steroids, 47, 35-45 (1986).
-
(1986)
Steroids
, vol.47
, pp. 35-45
-
-
Bird, J.1
Kim, H.P.2
Lee, H.J.3
-
6
-
-
0020510098
-
Specificity and inhibition of glucocorticoid-induced macrocortin secretion from rat peritoneal macrophages
-
Blackwell, G. J., Specificity and inhibition of glucocorticoid-induced macrocortin secretion from rat peritoneal macrophages. Br. J. Pharmacol., 79, 587-594 (1983).
-
(1983)
Br. J. Pharmacol.
, vol.79
, pp. 587-594
-
-
Blackwell, G.J.1
-
7
-
-
0020673689
-
Structure-activity relationships in the antiinflammatory steroids: A pattern-recognition approach
-
Bodor, N., Harget, A. J. and Philip, E. W., Structure-activity relationships in the antiinflammatory steroids: A pattern-recognition approach. J. Med. Chem., 26, 318-328 (1983).
-
(1983)
J. Med. Chem.
, vol.26
, pp. 318-328
-
-
Bodor, N.1
Harget, A.J.2
Philip, E.W.3
-
8
-
-
0000445323
-
Chemical and biological factors in the activity of adrenocortical steroids
-
Bush, I. E., Chemical and biological factors in the activity of adrenocortical steroids. Pharmacol. Rev., 14, 374-392 (1962).
-
(1962)
Pharmacol. Rev.
, vol.14
, pp. 374-392
-
-
Bush, I.E.1
-
9
-
-
0018844783
-
Effects of a new glucocorticoid, deflazacort on pituitary-adrenal function in man: A comparison with prednisolone
-
Criscuolo, D., Fraioli, F. and Bonifacio, V., Effects of a new glucocorticoid, deflazacort on pituitary-adrenal function in man: a comparison with prednisolone. Int. J. Clin. Pharmacol. Ther. Toxicol., 18, 37-41 (1980).
-
(1980)
Int. J. Clin. Pharmacol. Ther. Toxicol.
, vol.18
, pp. 37-41
-
-
Criscuolo, D.1
Fraioli, F.2
Bonifacio, V.3
-
10
-
-
0016931550
-
Steroid structure and steroid activity
-
Elks, J., Steroid structure and steroid activity. Br. J. Dermatol., 94, 2-13 (1976).
-
(1976)
Br. J. Dermatol.
, vol.94
, pp. 2-13
-
-
Elks, J.1
-
11
-
-
0018755280
-
2 inhibitor which prevents prostaglandin generation
-
2 inhibitor which prevents prostaglandin generation. Nature, 278, 456-459 (1979).
-
(1979)
Nature
, vol.278
, pp. 456-459
-
-
Flower, R.J.1
Blackwell, G.J.2
-
12
-
-
0013028130
-
Anti-inflammatory steroids
-
Verderame, M. (Ed), Boca Raton, Florida
-
Green, M. J. and Lutsky, B. N., Anti-inflammatory steroids: In handbook of Cardiovascular and anti-inflammatory agents, Verderame, M. (Ed), Boca Raton, Florida, 1986.
-
(1986)
Handbook of Cardiovascular and Anti-inflammatory Agents
-
-
Green, M.J.1
Lutsky, B.N.2
-
13
-
-
0024548602
-
A novel class of local anti-inflammatory steroids
-
2nd communication
-
Heiman, A. S., Kim, H. P., Taraporewala, I. B. and Lee, H. J., A novel class of local anti-inflammatory steroids. 2nd communication, Arzneim.-Forsch./Drug Res., 39, 362-267 (1989).
-
(1989)
Arzneim.-Forsch./Drug Res.
, vol.39
, pp. 362-1267
-
-
Heiman, A.S.1
Kim, H.P.2
Taraporewala, I.B.3
Lee, H.J.4
-
14
-
-
0025329249
-
New potent topical anti-inflammatory steroids with reduced side effects: Derivatives of steroid-16-carboxy esters
-
Heiman, A. S., Taraporewala, I. B., McLean, H. M., Hong, D. and Lee, H. J., New potent topical anti-inflammatory steroids with reduced side effects: derivatives of steroid-16-carboxy esters. J. Pharm. Sci., 79, 617-621 (1990).
-
(1990)
J. Pharm. Sci.
, vol.79
, pp. 617-621
-
-
Heiman, A.S.1
Taraporewala, I.B.2
McLean, H.M.3
Hong, D.4
Lee, H.J.5
-
15
-
-
0031009643
-
New steroidal anti-inflammatory antedrug
-
Heiman, A. S., Ko, D.-H., Chen, M. and Lee, H. J., New steroidal anti-inflammatory antedrug, Steroids, 62, 491-499 (1997).
-
(1997)
Steroids
, vol.62
, pp. 491-499
-
-
Heiman, A.S.1
Ko, D.-H.2
Chen, M.3
Lee, H.J.4
-
16
-
-
0032443703
-
New steroidal anti-inflammatory antedrugs bind to macrophage glucocorticoid receptors and inhibit nitric oxide generation
-
Heiman, A. S., Hickman, F., Ko, D.-H. and Lee, H. J., New steroidal anti-inflammatory antedrugs bind to macrophage glucocorticoid receptors and inhibit nitric oxide generation. Steroids, 63, 644-649 (1998).
-
(1998)
Steroids
, vol.63
, pp. 644-649
-
-
Heiman, A.S.1
Hickman, F.2
Ko, D.-H.3
Lee, H.J.4
-
17
-
-
76549251874
-
Proceedings of the Staff Meetings of the Mayo Clinic
-
Hench, P. S., Kendall, E. C., Slocumb, C. H. and Polley, H. F., Proceedings of the Staff Meetings of the Mayo Clinic. Arch. Int. Med., 85, 545-666 (1950).
-
(1950)
Arch. Int. Med.
, vol.85
, pp. 545-666
-
-
Hench, P.S.1
Kendall, E.C.2
Slocumb, C.H.3
Polley, H.F.4
-
18
-
-
0021989421
-
Synthesis of a new anti-inflammatory steroidal acid ester: Methyl 11β-hydroxy-3,20-dioxo-1,4-pregnadien-21-oate
-
Khalil, M. A., Lay, J. C. and Lee, H. J., Synthesis of a new anti-inflammatory steroidal acid ester: methyl 11β-hydroxy-3,20-dioxo-1,4-pregnadien-21-oate. J. Pharm. Sci., 74, 180-183 (1985).
-
(1985)
J. Pharm. Sci.
, vol.74
, pp. 180-183
-
-
Khalil, M.A.1
Lay, J.C.2
Lee, H.J.3
-
19
-
-
0002104784
-
New antiinflammatory steroids: [17α,16α-d]-isoxazoline derivatives of prednisolone and 9α-fluoroprednisolone
-
Khalil, M. A., Maponya, M. F., Ko, D.-H., You, Z. and Lee, H. J., New antiinflammatory steroids: [17α,16α-d]-isoxazoline derivatives of prednisolone and 9α-fluoroprednisolone. J. Med. Chem. Res. 6, 52-60 (1996).
-
(1996)
J. Med. Chem. Res.
, vol.6
, pp. 52-60
-
-
Khalil, M.A.1
Maponya, M.F.2
Ko, D.-H.3
You, Z.4
Lee, H.J.5
-
20
-
-
0028225668
-
Colonic mucosa-specific pro-antedrugs for oral treatment of ulcerative colitis: Design, synthesis and fate of methyl 20-glucopyranosyloxyprednisolonates
-
Kimura, T, Yamaguchi, T., Usuki, K., Kurosaki, Y., Nakayama, T., Fujiwara, Y., Matsuda, Y., Unno, K. and Suzuki, T., Colonic mucosa-specific pro-antedrugs for oral treatment of ulcerative colitis: design, synthesis and fate of methyl 20-glucopyranosyloxyprednisolonates. J. Control. Release, 30, 125-135 (1994).
-
(1994)
J. Control. Release
, vol.30
, pp. 125-135
-
-
Kimura, T.1
Yamaguchi, T.2
Usuki, K.3
Kurosaki, Y.4
Nakayama, T.5
Fujiwara, Y.6
Matsuda, Y.7
Unno, K.8
Suzuki, T.9
-
21
-
-
0000506441
-
New anti-inflammatory steroids: [17α,16α-d]-3′-hydroxy-iminoformylisoxazoline derivatives of prednisolone and 9α-fluoroprednisolone
-
Ko, D.-H., Maponya, M. F., Khalil, M.A., You, Z. and Lee, H. J., New anti-inflammatory steroids: [17α,16α-d]-3′-hydroxy-iminoformylisoxazoline derivatives of prednisolone and 9α-fluoroprednisolone. J. Med. Chem. Res. 7, 313-323 (1997).
-
(1997)
J. Med. Chem. Res.
, vol.7
, pp. 313-323
-
-
Ko, D.-H.1
Maponya, M.F.2
Khalil, M.A.3
You, Z.4
Lee, H.J.5
-
22
-
-
0022341856
-
Hydrolysis of methyl steroid 21-oates and acetyl steroid 21-ols by rat liver microsomes
-
Kumari, D. and Lee, H. J., Hydrolysis of methyl steroid 21-oates and acetyl steroid 21-ols by rat liver microsomes. Drug Metab. Desp., 13, 627-629 (1985).
-
(1985)
Drug Metab. Desp.
, vol.13
, pp. 627-629
-
-
Kumari, D.1
Lee, H.J.2
-
23
-
-
0028970008
-
New steroidal antiinflammatory antedrugs: Steroidal [17α,16α-d]-3′-carethoxyisoxazolines
-
Kwon, T., Heiman, A. S., Oriaku, E. T., Yoon, K. and Lee, H. J., New steroidal antiinflammatory antedrugs: steroidal [17α,16α-d]-3′-carethoxyisoxazolines. J. Med. Chem., 38, 1048-1051 (1995).
-
(1995)
J. Med. Chem.
, vol.38
, pp. 1048-1051
-
-
Kwon, T.1
Heiman, A.S.2
Oriaku, E.T.3
Yoon, K.4
Lee, H.J.5
-
24
-
-
0016419897
-
Synthesis of novel anti-inflammatory steroids
-
Laurent, H., Gerhards, E. and Weichert, R., Synthesis of novel anti-inflammatory steroids. Angew. Chem. Int. Ed. Engl., 14, 65-69 (1975).
-
(1975)
Angew. Chem. Int. Ed. Engl.
, vol.14
, pp. 65-69
-
-
Laurent, H.1
Gerhards, E.2
Weichert, R.3
-
25
-
-
0020037486
-
Anti-inflammatory steroids without pituitary adrenal suppression
-
Lee, H. J. and Soliman, M. R. I., Anti-inflammatory steroids without pituitary adrenal suppression. Science, 215, 989-991 (1982).
-
(1982)
Science
, vol.215
, pp. 989-991
-
-
Lee, H.J.1
Soliman, M.R.I.2
-
26
-
-
0021706638
-
Antedrug: A conceptual basis for safer antiinflammatory steroids
-
Lee, H. J., Khalil, M. A. and Lee, J. W., Antedrug: A conceptual basis for safer antiinflammatory steroids. Drugs Expl. Clin. Res., 10, 835-844 (1984).
-
(1984)
Drugs Expl. Clin. Res.
, vol.10
, pp. 835-844
-
-
Lee, H.J.1
Khalil, M.A.2
Lee, J.W.3
-
27
-
-
0022297908
-
Binding of ester and amide epimers of 20-dihydro-prednisolonic acid to cytosol receptors and their acute pharmacological activities in rats
-
Lee, J. W. and Lee, H. J., Binding of ester and amide epimers of 20-dihydro-prednisolonic acid to cytosol receptors and their acute pharmacological activities in rats. J. Steroid. Biochem., 23, 943-948 (1985).
-
(1985)
J. Steroid. Biochem.
, vol.23
, pp. 943-948
-
-
Lee, J.W.1
Lee, H.J.2
-
28
-
-
0000695294
-
New steroidal anti-inflammatory drugs
-
Rainsford, K.D. & Velo, G. P. (Eds.)
-
Lee, H. J., Heiman, A. S. and Taraporewala, B., New steroidal anti-inflammatory drugs: Rainsford, K.D. & Velo, G. P. (Eds.). New developments in antirheumatic therapy, vol. III. pp. 153-186 (1989).
-
(1989)
New Developments in Antirheumatic Therapy
, vol.3
, pp. 153-186
-
-
Lee, H.J.1
Heiman, A.S.2
Taraporewala, B.3
-
29
-
-
0001481109
-
Recent advances in prodrugs and antedrugs
-
September
-
Lee, H. J., You, Z., Ko, D.-H. and McLean, H. M., Recent advances in prodrugs and antedrugs. Curr. Opinion in Drug Discov. Dev. September vol. 1, No. 2, 235-244 (1998a).
-
(1998)
Curr. Opinion in Drug Discov. Dev.
, vol.1
, Issue.2
, pp. 235-244
-
-
Lee, H.J.1
You, Z.2
Ko, D.-H.3
McLean, H.M.4
-
30
-
-
0031725758
-
New steroidal antiinflammatory agents: Prednisolone derivatives with a isoxazoline fusion at the 16- and 17-carbons and an alkyl carbonylate at the 16α-position
-
Lee, H. J., You, Z., Ko, D.-H. and Yoon, K. J., New steroidal antiinflammatory agents: prednisolone derivatives with a isoxazoline fusion at the 16- and 17-carbons and an alkyl carbonylate at the 16α-position. Drug Exptl. Clin. Res., 24 (2), 57-66 (1998b).
-
(1998)
Drug Exptl. Clin. Res.
, vol.24
, Issue.2
, pp. 57-66
-
-
Lee, H.J.1
You, Z.2
Ko, D.-H.3
Yoon, K.J.4
-
31
-
-
0008590343
-
Conversion of steroid-17-yl glyoxals to epimeric glycolic esters
-
Lewbart, M. L. and Mattox, V. R., Conversion of steroid-17-yl glyoxals to epimeric glycolic esters. J. Org. Chem., 28, 1779-1786 (1963).
-
(1963)
J. Org. Chem.
, vol.28
, pp. 1779-1786
-
-
Lewbart, M.L.1
Mattox, V.R.2
-
32
-
-
71849104860
-
Protein measurement with the Folin phenol reagent
-
Lowry, O. H., Rosebrough, N. J., Farr, A. L. and Randall, R. J., Protein measurement with the Folin phenol reagent. J. Biol. Chem., 193, 265-275 (1951).
-
(1951)
J. Biol. Chem.
, vol.193
, pp. 265-275
-
-
Lowry, O.H.1
Rosebrough, N.J.2
Farr, A.L.3
Randall, R.J.4
-
33
-
-
0015102877
-
Synthesis of steroids containing the α-keto acid sidechain
-
Monder, C., Synthesis of steroids containing the α-keto acid sidechain. Steroids, 18, 187-194 (1971).
-
(1971)
Steroids
, vol.18
, pp. 187-194
-
-
Monder, C.1
-
34
-
-
0017181158
-
Partial purification of rabbit aorta contracting substance-releasing factor and inhibition of its activity by anti-inflammatory steroids
-
Nijkamp, F. P., Flower, R. J., Moncado, S. and Vane, J. R., Partial purification of rabbit aorta contracting substance-releasing factor and inhibition of its activity by anti-inflammatory steroids, Nature, 263, 479-482 (1976).
-
(1976)
Nature
, vol.263
, pp. 479-482
-
-
Nijkamp, F.P.1
Flower, R.J.2
Moncado, S.3
Vane, J.R.4
-
35
-
-
0021743881
-
Systemic effects of chronically administered methyl prednisolonate and methyl 17-deoxyprednisolonate
-
Olejniczak, E. and Lee, H. J., Systemic effects of chronically administered methyl prednisolonate and methyl 17-deoxyprednisolonate. Steroids, 43, 657-662, (1984).
-
(1984)
Steroids
, vol.43
, pp. 657-662
-
-
Olejniczak, E.1
Lee, H.J.2
-
36
-
-
0002469339
-
Locally active corticoids: Structure activity relationships
-
Wilson, L. and Marks, R. (Eds.) Livingstone, Edingburgh, U.K.
-
Phillips, G. H., Locally active corticoids: structure activity relationships. In Wilson, L. and Marks, R. (Eds.). Mechanism of topical coticoid activity. Livingstone, Edingburgh, U.K., pp. 1-18, 1976.
-
(1976)
Mechanism of Topical Coticoid Activity
, pp. 1-18
-
-
Phillips, G.H.1
-
37
-
-
0002469339
-
Mechanism of topical corticosteroid activity
-
London
-
Phillips, G. H., Mechanism of topical corticosteroid activity. Glaxo symposium, London, 1976.
-
(1976)
Glaxo Symposium
-
-
Phillips, G.H.1
-
38
-
-
0019423008
-
Corticoids and cultured human epidermal keratinocytes: Specific intracellular binding and clinical efficacy
-
Ponec, M., Kempenaar, J. A. and Kloet, E. R., Corticoids and cultured human epidermal keratinocytes: specific intracellular binding and clinical efficacy. J. Invest. Dermatol., 76, 211-214 (1981).
-
(1981)
J. Invest. Dermatol.
, vol.76
, pp. 211-214
-
-
Ponec, M.1
Kempenaar, J.A.2
Kloet, E.R.3
-
39
-
-
0343530553
-
Anti-inflammatory steroid
-
Scherer, R. A. and Whitehouse, M. W. (Eds.)
-
Popper, T. L. and Watnick, A. S., Anti-inflammatory steroid: Scherer, R. A. and Whitehouse, M. W. (Eds.). Anti-i nflammatory Agents-Chemistry and Pharmacology, vol. 1, pp. 245-294 (1974).
-
(1974)
Anti-i Nflammatory Agents-Chemistry and Pharmacology
, vol.1
, pp. 245-294
-
-
Popper, T.L.1
Watnick, A.S.2
-
40
-
-
0345284792
-
Comparative efficacy of topical anti-inflammatory corticosteroids
-
Schlagel, C.A., Comparative efficacy of topical anti-inflammatory corticosteroids. J. Pharm. Sci., 54, 335-354 (1965).
-
(1965)
J. Pharm. Sci.
, vol.54
, pp. 335-354
-
-
Schlagel, C.A.1
-
41
-
-
0019907613
-
Glucocorticoid-specific binding: Structure-activity relationship
-
Shroot, B., Caron, J. C. and Ponec, M., Glucocorticoid-specific binding: Structure-activity relationship. Br. J. Dermatol., 107 (suppl 23), 30-34 (1982).
-
(1982)
Br. J. Dermatol.
, vol.107
, Issue.23 SUPPL.
, pp. 30-34
-
-
Shroot, B.1
Caron, J.C.2
Ponec, M.3
-
42
-
-
0019465972
-
Local antiinflammatory activity of acid ester derivatives of prednisolone
-
Soliman, M. R. I. and Lee, H. J., Local antiinflammatory activity of acid ester derivatives of prednisolone. Res. Commun. Pathol. Pharmacol., 33, 357-360 (1981).
-
(1981)
Res. Commun. Pathol. Pharmacol.
, vol.33
, pp. 357-360
-
-
Soliman, M.R.I.1
Lee, H.J.2
-
43
-
-
0024496817
-
A novel class of local anti-inflammatory steroids. 1st communication
-
Taraporewala, I. B., Kim, H. B., Heiman, A. S. and Lee, H. J., A novel class of local anti-inflammatory steroids. 1st communication, Arzneim.-Forsch. / Drug Res., 39, 21-25 (1989).
-
(1989)
Arzneim.-Forsch. / Drug Res.
, vol.39
, pp. 21-25
-
-
Taraporewala, I.B.1
Kim, H.B.2
Heiman, A.S.3
Lee, H.J.4
-
44
-
-
0018695570
-
Synthesis and anti-inflammatory properties of Budesonide, a new non-halogenated glucocorticoid with high local activity
-
Thalen, A. and Brattsand, E., Synthesis and anti-inflammatory properties of Budesonide, a new non-halogenated glucocorticoid with high local activity. Arzneim-Forsch Drug Res., 29 (II), 687-690 (1979).
-
(1979)
Arzneim-Forsch Drug Res.
, vol.29
, Issue.2
, pp. 687-690
-
-
Thalen, A.1
Brattsand, E.2
-
45
-
-
0013806318
-
A bioassay for the concomitant assessment of the antiphlogistic and thymolytic activities of topically applied corticosteroid
-
Tonneli, G., Thiabault, L. and Ringler, J., A bioassay for the concomitant assessment of the antiphlogistic and thymolytic activities of topically applied corticosteroid. Endocrinol., 77, 625-634 (1965).
-
(1965)
Endocrinol.
, vol.77
, pp. 625-634
-
-
Tonneli, G.1
Thiabault, L.2
Ringler, J.3
-
46
-
-
0028970020
-
Suppression of the Mattox rearrangement of 16α-cyanoprednisolones in acid: Synthesis of methyl 16α-prednisolonecarboxylates
-
You, Z., Khalil, M. A., Ko, D.-H. and Lee, H. J., Suppression of the Mattox rearrangement of 16α-cyanoprednisolones in acid: synthesis of methyl 16α-prednisolonecarboxylates. Tetrahedron Lett., 36(19), 3303-3306 (1995).
-
(1995)
Tetrahedron Lett.
, vol.36
, Issue.19
, pp. 3303-3306
-
-
You, Z.1
Khalil, M.A.2
Ko, D.-H.3
Lee, H.J.4
-
47
-
-
0030056342
-
One step conversion of highly dipolarophilic olefins to α-hydroxy-β-cyanoadducts with metal fulminate
-
You, Z. and Lee, H. J., One step conversion of highly dipolarophilic olefins to α-hydroxy-β-cyanoadducts with metal fulminate. Tetrahedron Lett., 37(8), 1165-1168 (1996).
-
(1996)
Tetrahedron Lett.
, vol.37
, Issue.8
, pp. 1165-1168
-
-
You, Z.1
Lee, H.J.2
|