New aspects of the phosphatase VHZ revealed by a high-resolution structure with vanadate and substrate screening

Biochemistry

Volumn 51, Issue 49, 2012, Pages 9869-9879

  Kuznetsov, Vyacheslav I ^a   Hengge, Alvan C ^a   Johnson, Sean J ^a  

^a UTAH STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE; HIGH-RESOLUTION STRUCTURES; PHOSPHORYLATED PEPTIDES; PHOSPHOTYROSINE; PROTEIN-TYROSINE PHOSPHATASE; SCREENING ANALYSIS; SEQUENCE SIMILARITY; STRUCTURAL COMPARISON; STRUCTURAL ELEMENTS; SUBSTRATE RECOGNITION;

AMINO ACIDS; PEPTIDES; PHOSPHORYLATION;

PHOSPHATASES;

PEPTIDE; PHOSPHOSERINE; PHOSPHOTHREONINE; PHOSPHOTYROSINE; PROTEIN TYROSINE PHOSPHATASE; VANADIC ACID;

ARTICLE; CATALYSIS; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME CONFORMATION; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SUBSTRATE; HUMAN; HYDROLYSIS; MOLECULAR RECOGNITION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SCREENING; STRUCTURE ANALYSIS;

BASE SEQUENCE; CRYSTALLIZATION; DNA PRIMERS; HYDROGEN BONDING; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PROTEIN TYROSINE PHOSPHATASES; SUBSTRATE SPECIFICITY; VANADATES;

EID: 84870872419     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi300908y     Document Type: Article

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